!direction	-1
!num_genes	181
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Lubiprostone
!smiles	CCCCC(C1(CCC2C(O1)CC(=O)C2CCCCCCC(=O)O)O)(F)F
!drugbank_id	DB01046
!pubchem_cid	656719
!cell_type	NA
!organism	mouse
!end_metadata
GSDMC	-0.132712
DNASE1	-0.124586
CTRB2	-0.114967
CELA2A	-0.098455
CELA1	-0.095767
OAT	-0.093099
PLA2G4C	-0.082551
PRSS2	-0.077642
CPB1	-0.076777
CPA1	-0.076721
PNLIP	-0.075817
RETNLB	-0.071737
LCT	-0.063087
CELA3B	-0.062589
GPX2	-0.062254
OLFM4	-0.062067
HSPA8	-0.059980
USMG5	-0.058035
HIST1H2BI	-0.056423
NAALADL1	-0.054086
C15orf48	-0.053006
CLPS	-0.052477
COL3A1	-0.049071
CEL	-0.048988
HSPD1	-0.046544
CLCA1	-0.044907
ANXA4	-0.044803
CTRL	-0.044017
AADAC	-0.040505
PNLIPRP2	-0.039906
EIF4A2	-0.039316
REG4	-0.038272
HSP90B1	-0.037315
AOC1	-0.037284
SPINK4	-0.036443
HSP90AA1	-0.034960
PCNA	-0.033092
PMP22	-0.032372
HSPA5	-0.032292
LPCAT3	-0.031159
CUBN	-0.030561
PSMB7	-0.030249
CYP2C9	-0.030193
REG1B	-0.029817
HSPH1	-0.029173
ATP5J	-0.028143
PGAM1	-0.027777
NTS	-0.027330
PNLIPRP1	-0.027020
MANF	-0.026950
GHITM	-0.026418
RFK	-0.026249
SCIN	-0.025932
CD74	-0.025601
SERP1	-0.025586
IL33	-0.025169
ACAT1	-0.024556
CYP4F12	-0.024345
CYP4V2	-0.023841
PPIA	-0.023744
SNX3	-0.023697
AGR2	-0.023673
ADAMDEC1	-0.023393
ACTG2	-0.023305
LAP3	-0.022927
CHORDC1	-0.022915
PGD	-0.022242
CYP2C18	-0.022115
RNASE1	-0.021828
LDHA	-0.021399
DUSP6	-0.021166
CLRN3	-0.020932
PGK1	-0.020712
CKB	-0.020673
PLS1	-0.020445
CGREF1	-0.020396
ACSL5	-0.020250
MUC2	-0.020221
CYP2B6	-0.020077
AAMDC	-0.020075
YWHAQ	-0.019895
HSP90AB1	-0.019892
CEACAM1	-0.019881
CTNNB1	-0.019812
COX7A1	-0.019489
MGAT4C	-0.019452
DNAJA1	-0.019439
CPS1	-0.019336
NDUFV3	-0.019270
RNF5	-0.019261
ELF3	-0.019178
SPARC	-0.018881
HNF4G	-0.018650
TVP23B	-0.018631
MINOS1	-0.018594
TUBA1A	-0.018555
NDUFA9	-0.018406
BST1	-0.018336
C14orf2	-0.018249
CLDN15	-0.018235
KPNA2	-0.018192
TPI1	-0.018155
NDUFC1	-0.017990
MME	-0.017953
PPP4C	-0.017826
LGALS2	-0.017779
TALDO1	-0.017771
CASP1	-0.017727
BANF1	-0.017704
NDUFS7	-0.017688
ERO1L	-0.017688
RAN	-0.017564
ARF1	-0.017378
DYNLL1	-0.017095
HSPE1	-0.017012
EMG1	-0.016976
GSTK1	-0.016925
NDUFA8	-0.016917
UQCRFS1	-0.016798
IL13RA1	-0.016688
TRIM31	-0.016667
NDUFB6	-0.016532
MYL9	-0.016515
DDC	-0.016481
ME1	-0.016428
FTL	-0.016261
AZIN1	-0.016232
TSC22D1	-0.016202
MAOB	-0.016152
SERF2	-0.016044
ATP5J2	-0.015970
PRDX1	-0.015789
DDX17	-0.015578
RPS27L	-0.015542
MIEN1	-0.015529
MEP1A	-0.015529
IMMP1L	-0.015525
TAX1BP3	-0.015506
PLBD1	-0.015503
TMEM208	-0.015318
SKP1	-0.015244
RETSAT	-0.015227
MAOA	-0.015225
COL6A3	-0.015011
GIP	-0.014986
ATP6V0E1	-0.014946
COL4A1	-0.014807
C18orf32	-0.014696
ASAH2	-0.014567
NDUFB5	-0.014444
COPZ1	-0.014407
EMC2	-0.014399
NADK	-0.014302
SLC7A7	-0.014277
NDUFA3	-0.014272
SRSF1	-0.014148
KITLG	-0.014137
PSMB5	-0.014129
DSC2	-0.013987
PDHA1	-0.013985
LGALS1	-0.013746
CASP7	-0.013721
PGRMC1	-0.013656
COA3	-0.013609
SSR3	-0.013572
CA4	-0.013546
IGSF23	-0.013449
SLC5A12	-0.013441
CLINT1	-0.013314
GPX1	-0.013265
NSFL1C	-0.013227
C11orf86	-0.013199
NDUFA4	-0.013184
DBI	-0.013162
SCP2	-0.013155
HLA-DQB1	-0.013050
UQCR11	-0.013019
MCFD2	-0.013017
MORF4L2	-0.013000
KLHL9	-0.012963
NDUFS8	-0.012945