!direction	-1
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	MK-886
!smiles	CC(C)C1=CC2=C(C=C1)N(C(=C2SC(C)(C)C)CC(C)(C)C(=O)O)CC3=CC=C(C=C3)Cl
!pubchem_cid	3651377
!cell_type	H720 cell line(lung cancer)
!organism	human
!end_metadata
RPS10	-0.120463
TUBA1A	-0.101691
RPL36A	-0.101571
RPS18	-0.098288
RPL23A	-0.097400
RPL30	-0.096715
RPL39	-0.095779
RPS20	-0.095211
RPL24	-0.093788
RPS13	-0.092707
PSMD10	-0.091763
RPLP0	-0.091333
RPL9	-0.091122
RPL12	-0.088903
RPL41	-0.088688
RPL32	-0.086988
RPS29	-0.086625
TPT1	-0.086378
RPL8	-0.085649
RPS4X	-0.084988
UBC	-0.084751
GAPDH	-0.084620
COX2	-0.084176
RPL34	-0.084145
RPL36	-0.084055
RPL13A	-0.083654
RPS7	-0.082670
RPL19	-0.082435
RPSA	-0.080990
RPL3	-0.080559
RPS2	-0.079865
TUBA1B	-0.079096
RPS3	-0.077626
RPL27	-0.077393
RPL4	-0.077131
HSPA8	-0.076193
TUBA1C	-0.075181
USMG5	-0.075092
RPS3A	-0.074938
PARK7	-0.074842
MIF	-0.073457
FAU	-0.073408
RPL35	-0.072712
RPL21	-0.071814
SNRPD2	-0.071647
RPS6	-0.070684
RPL6	-0.070483
MRFAP1	-0.070448
NDUFS6	-0.070393
HSP90AA1	-0.069163
RPS16	-0.068864
RPL17	-0.068214
HMGN2	-0.067922
H2AFZ	-0.067206
YBX1	-0.067051
RPL7A	-0.066541
EEF1G	-0.066081
PPIA	-0.065817
COX6C	-0.065726
EEF1B2	-0.064498
OAZ1	-0.064448
ACTB	-0.063465
RPS23	-0.062506
RPS5	-0.062406
COX7A2	-0.061617
EEF1A1	-0.061212
NME1	-0.061167
RPS17	-0.061051
ACTG1	-0.058957
UQCRH	-0.058560
RAN	-0.058026
RPS8	-0.057894
UBA52	-0.057824
HMGN3	-0.057593
RPS15	-0.057439
RPS25	-0.057140
TUBB	-0.057010
YWHAQ	-0.056918
SUMO2	-0.056824
SNRPG	-0.056814
CHCHD2	-0.056710
FTL	-0.055898
ATG4A	-0.055624
RPS11	-0.055293
LDHA	-0.055128
TUBB2A	-0.053805
PPA1	-0.053712
RPS14P3	-0.053221
PRDX1	-0.052851
RPS21	-0.052723
EEF2	-0.052637
ATP5L	-0.051862
FTH1P5	-0.051526
NDUFB5	-0.050969
RPL11	-0.050730
LSM7	-0.050435
SLC25A5	-0.050389
SLC25A3	-0.050363
RPS19	-0.050109
TBCA	-0.050046
RPL13	-0.049968
ERH	-0.049907
ANP32B	-0.049576
RPL35A	-0.049570
RPS27	-0.049511
RPS26	-0.048633
RPL10A	-0.048473
SHFM1	-0.048269
RPLP1	-0.048191
UBE2S	-0.047978
NDUFB9	-0.047875
COX7C	-0.047144
SOD1	-0.047136
SRP14	-0.046960
HSP90AB1	-0.046737
SNHG5	-0.046322
NDUFAB1	-0.046097
TMA7	-0.045348
NDUFA4	-0.045169
TUBB3	-0.045131
PTMA	-0.045013
RPS12	-0.044871
PSMA6	-0.044587
SRP9	-0.044563
RPL28	-0.044372
BEX1	-0.044173
HMGB1	-0.044115
FTH1	-0.044092
RPL5	-0.043979
TRMT112	-0.043754
RPS9	-0.043213
GNB2L1	-0.043151
TUBB4B	-0.042961
NGFRAP1	-0.042956
SNHG6	-0.042888
NDUFA13	-0.042729
COX4I1	-0.042567
RPL36AL	-0.042245
RPL37A	-0.042205
HINT1	-0.042074
COX6B1	-0.042041
CFL1	-0.041745
NPM1	-0.041426
DBI	-0.041300
SLIRP	-0.041282
KARS	-0.041277
PTTG1	-0.041156
RPS24	-0.040926
RPL31	-0.040806
HSPB1	-0.040674
C12orf57	-0.040573
JTB	-0.040399
RPL22	-0.040074
ATP5H	-0.039965
H3F3B	-0.039931
PPIB	-0.039835
FBL	-0.039812
NACA	-0.039705
UQCRQ	-0.039161
RPA3	-0.039088
ODC1	-0.038875
TUBB2B	-0.038616
COX8A	-0.038480
DYNLL1	-0.038420
NAE1	-0.037727
COX6A1	-0.037626
RPL22L1	-0.037525
SNRPB	-0.036880
GPX4	-0.036849
C14orf166	-0.036540
HSPE1	-0.036431
TMEM14B	-0.036279
DEK	-0.036254
POLR2J	-0.036238
ATP5J	-0.036170
CCT2	-0.036147
MLLT11	-0.036064
NDUFA12	-0.035808
NHP2	-0.035279
CALM2	-0.034746
MRPL36	-0.034642
YWHAG	-0.034493
RPL29	-0.034384
CCT7	-0.034148
NOP10	-0.034073
RPL7L1	-0.033990
LAPTM4B	-0.033973
RPS27A	-0.033917
DYNLT1	-0.033898
PSMB3	-0.033881
HMGN1	-0.033647
ACAT2	-0.033622
CKS2	-0.033443
CD24	-0.033296
HNRNPA1	-0.033059
FAM96A	-0.033020
RPL27A	-0.032940
PTGES3	-0.032939
ATP5E	-0.032893
CCT3	-0.032851
RFC4	-0.032757
GTF3C6	-0.032723
TMEM14A	-0.032607
DPYSL2	-0.032582
MMADHC	-0.032551
PABPC3	-0.032472
DDX39A	-0.032405
KIAA0101	-0.032360
ATP5G3	-0.032041
C14orf2	-0.031985
KPNA2	-0.031979
GLO1	-0.031942
MAGEA3	-0.031890
COX5B	-0.031845
HNRNPK	-0.031627
RPL7	-0.031530
TMEM14C	-0.031518
UQCRB	-0.031446
TFF3	-0.031247
EIF1	-0.031209
RPL18	-0.031080
TMEM258	-0.030937
VDAC2	-0.030931
EIF3H	-0.030891
PRDX4	-0.030861
ARPC1A	-0.030697
SUB1	-0.030687
EIF3L	-0.030557
CBX1	-0.030546
SNRPD3	-0.030454
SLC25A6	-0.030394
ENO1	-0.030368
ANXA2	-0.030222
PSMB1	-0.030095
DNAJB11	-0.029945
MRPL3	-0.029868
CCT5	-0.029824
FDFT1	-0.029715
UQCRFS1	-0.029573
PSMD14	-0.029465
RPL38	-0.029342
SSR4	-0.029302
PGAM1	-0.029298
TOMM20	-0.029288
CUTA	-0.029154
VBP1	-0.029141
TMSB10	-0.029113
PHB2	-0.028935
SEC11C	-0.028930
RPL23	-0.028827
PPP1CC	-0.028626
UCHL1	-0.028592
GGCT	-0.028522
MAGEA6	-0.028467
HSBP1	-0.028450
PSMB4	-0.028341
NSA2	-0.028286
PCNA	-0.028244
SNRPF	-0.028239
ALDOA	-0.028190
GMNN	-0.028156
NDUFB11	-0.028154
RPL15	-0.028122
RPN2	-0.027999
LBR	-0.027861
FAM96B	-0.027803
RPS15A	-0.027767
TRMT5	-0.027543
OST4	-0.027457
ATP5A1	-0.027372
PBK	-0.027369
MRPS24	-0.027339
ATP5B	-0.027140
HIST1H2BK	-0.027087
RPLP2	-0.026942
PSMD2	-0.026896
PTPLAD1	-0.026818
GTF3A	-0.026779
NEDD8	-0.026745
NAP1L1	-0.026502
DUT	-0.026494
MZT2A	-0.026489
MTCH1	-0.026399
ATP6V0B	-0.026318
AP2M1	-0.026263
LAPTM4A	-0.025969
COX7B	-0.025827
RPL14	-0.025618
FABP5	-0.025465
RPL26	-0.025442
RPL37	-0.025297
EIF4A1	-0.025277
APEX1	-0.025223
DHX15	-0.025175
PDCD10	-0.025065
DNAJA1	-0.025050
SF3B5	-0.024964
NDUFA1	-0.024938
POMP	-0.024874
MRPL33	-0.024837
NDUFA11	-0.024715
FDPS	-0.024693
TYMS	-0.024690
PRDX5	-0.024550
NDUFB2	-0.024518
UBE2E3	-0.024380
SERF2	-0.024303
CYC1	-0.024165
ATP5F1	-0.024069
PSMG2	-0.024036
EIF2A	-0.023945
TMEM123	-0.023924
BOLA3	-0.023888
CSNK2B	-0.023883
TCEB2	-0.023789
NPTN	-0.023727
VDAC3	-0.023664
ZWINT	-0.023482
MRPS33	-0.023478
ATP5J2	-0.023373
SEC11A	-0.023364
ARL6IP1	-0.023274
RTN4	-0.023239
ATF4	-0.023167
CCT8	-0.023165
UXT	-0.023141
TRA2B	-0.023113
GNG5	-0.023091
SRSF9	-0.023026
HSPD1	-0.023025
BTF3	-0.022911
ARPC3	-0.022878
MGST1	-0.022874
RPS14	-0.022819
DAD1	-0.022762
PSMC5	-0.022714
POLR2H	-0.022520
DDX5	-0.022483
MT2A	-0.022397
RPS28	-0.022322
ILF2	-0.022214
PFDN5	-0.022120
SEP15	-0.022061
HMGB2	-0.022012
EPCAM	-0.021998
GPI	-0.021981
C1orf43	-0.021966
ATP5I	-0.021960
PFN2	-0.021789
CDK2AP1	-0.021782
TALDO1	-0.021666
HNRNPAB	-0.021656
UFC1	-0.021468
NONO	-0.021453
DYNC1I2	-0.021450
IARS	-0.021443
PABPC1	-0.021440
C20orf24	-0.021420
PSMA4	-0.021413
NARS	-0.021386
CCT6A	-0.021324
CDK4	-0.021303
IFI30	-0.021256
EIF3E	-0.021229
B2M	-0.021227
METTL5	-0.021225
IGFBP2	-0.021116
UQCR11	-0.021114
HES6	-0.020983
PIGP	-0.020847
MRPL18	-0.020821
PRDX2	-0.020817
EIF3K	-0.020760
ATP6	-0.020744
ATRAID	-0.020738
COL4A5	-0.020726
SRSF2	-0.020619
HNRNPA2B1	-0.020559
SEC61B	-0.020481
SNX3	-0.020457
MAGEA12	-0.020381
APOA1BP	-0.020339
ADI1	-0.020317
UBE2C	-0.020314
HUWE1	-0.020259
UBA2	-0.020155
MRPL51	-0.020138
GHITM	-0.019981
CFAP20	-0.019959
PSMC1	-0.019956
TPI1	-0.019941
SEC61G	-0.019929
SF3B6	-0.019874
TDP2	-0.019825
GABARAP	-0.019815
NUSAP1	-0.019693
SSB	-0.019690
RRM2	-0.019677
NOL7	-0.019675
UCHL3	-0.019656
PSMB5	-0.019560
SNRPD1	-0.019560
CLIC1	-0.019504
YWHAB	-0.019496
MDH2	-0.019466
FIS1	-0.019441
GSTO1	-0.019433
ROMO1	-0.019363
UFD1L	-0.019327
NDUFB4	-0.019315
PLP2	-0.019298
NCBP2-AS2	-0.019241
UBE2T	-0.019236
OCIAD2	-0.019223
ATP5C1	-0.019158
POLR2G	-0.019135
HNRNPA0	-0.019073
CDIPT	-0.019047
ENOPH1	-0.019024
PSMA1	-0.018983
LSM4	-0.018980
GABARAPL2	-0.018947
CMC2	-0.018766
YWHAZ	-0.018756
SSR2	-0.018730
UBL5	-0.018700
PSMG1	-0.018638
CKS1B	-0.018607
CCT4	-0.018596
HAUS1	-0.018595
CNBP	-0.018565
BZW2	-0.018559
CBX3	-0.018543
MZT2B	-0.018537
TXNL4A	-0.018531
MSMO1	-0.018361
STARD7	-0.018351
CYCS	-0.018211
EMC4	-0.018201
MCUR1	-0.018127
NDUFV2	-0.018126
PHB	-0.018008
HDAC2	-0.017961
CKB	-0.017951
OAT	-0.017936
MTHFD2	-0.017844
CETN3	-0.017832
MYL6	-0.017770
EIF4A2	-0.017764
POP7	-0.017672
MEA1	-0.017664
HNRNPC	-0.017639
ERP29	-0.017624
NDUFB8	-0.017600
RPL26L1	-0.017575
CALM1	-0.017565
MYL12B	-0.017506
NDUFA8	-0.017468
CPSF3	-0.017424
ATP5O	-0.017389
RRM1	-0.017347
HIF1A	-0.017315
SNRPE	-0.017307
COX1	-0.017305
SRM	-0.017277
CCNG1	-0.017259
ATIC	-0.017252
RSL24D1	-0.017252
LINC00493	-0.017234
PSMA2	-0.017227
EDF1	-0.017174
NDUFB1	-0.017136
CD63	-0.017125
AP2S1	-0.017112
GNAS	-0.017099
PNMA1	-0.017089
PSMC6	-0.017084
TMEM106C	-0.017049
TMEM205	-0.017020
FEN1	-0.017019
PSMB7	-0.016969
AHCY	-0.016939
ATP6V1F	-0.016939
SPCS1	-0.016866
TMX1	-0.016864
PSMD8	-0.016842
PDLIM1	-0.016828
CHMP2A	-0.016828
GARS	-0.016793
SERBP1	-0.016759
PTRHD1	-0.016702
HNRNPH1	-0.016584
MRPL47	-0.016573
MDH1	-0.016525
MRPL15	-0.016503
MCM7	-0.016476
AMZ2	-0.016363
PCBP1	-0.016344
LGALS3BP	-0.016338
NDUFC2	-0.016337