!direction	-1
!num_genes	267
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!gene	PDK1
!cell	BrafV600E (Pten/-::Pdk1+/+)
!perturbation	Knockout
!disease	Melanoma
!end_metadata
HIST1H2AB	-0.056621
EBF2	-0.055306
CSN3	-0.055224
FOXS1	-0.053884
COL26A1	-0.053444
MEOX2	-0.049656
MXD3	-0.049212
KDM5D	-0.049100
HIST1H2AA	-0.048618
RAD54L	-0.048526
STRA6	-0.046456
KIF18B	-0.045353
CDCA8	-0.045352
GDF10	-0.045017
HIST1H2AM	-0.044917
BRIP1	-0.044817
KIF11	-0.044592
HIST1H2AH	-0.044252
SPC25	-0.043325
MCM3	-0.043112
IQGAP3	-0.042650
HIST1H2AJ	-0.042183
CENPM	-0.041942
MEOX1	-0.041397
LUM	-0.041354
KIF23	-0.041236
CDCA2	-0.040851
KCNAB2	-0.040644
SKA3	-0.040401
CCL11	-0.040365
ARHGEF39	-0.040264
TPMT	-0.040242
CEP55	-0.039715
RAD54B	-0.039700
HIST1H2AG	-0.039326
AMN	-0.039112
ASPM	-0.039070
MNS1	-0.039029
SLC15A2	-0.038880
TRPC3	-0.038874
FANCI	-0.038822
KRT8	-0.038765
SOX8	-0.038553
KIAA0101	-0.038403
RRM2	-0.038311
POLE	-0.038203
FANCD2	-0.038055
ESCO2	-0.038011
ERCC6L	-0.038000
ARG1	-0.037942
PLK1	-0.037840
NUP210	-0.037655
CDCA3	-0.037403
KIF2C	-0.037316
COL28A1	-0.037293
CCNE2	-0.036931
PRC1	-0.036820
STMN2	-0.036586
MCM10	-0.036534
CHTF18	-0.036485
KIF22	-0.036485
MCM5	-0.036323
FIGNL1	-0.036114
DEPDC1B	-0.035853
SIGLEC1	-0.035542
BIRC5	-0.035416
FAM132B	-0.035113
CHAF1B	-0.034772
CENPI	-0.034723
CCNB1	-0.034689
KIF4A	-0.034642
ASPHD2	-0.034489
CLDN1	-0.034391
KRT27	-0.034129
CDC20	-0.033999
PLXDC1	-0.033514
KRT71	-0.033482
SPDL1	-0.033399
COL15A1	-0.033159
C1QTNF2	-0.032765
TOP2A	-0.032752
SP7	-0.032451
PIF1	-0.032410
KLK10	-0.032275
RBL1	-0.032107
PTX3	-0.032061
PIDD	-0.032016
CDCA7	-0.031532
ISLR2	-0.031455
ASF1B	-0.031279
HEYL	-0.031114
CKAP2L	-0.031041
IL4I1	-0.031022
CENPP	-0.030892
CENPN	-0.030878
KBTBD6	-0.030724
SRPX	-0.030645
FAM64A	-0.030446
DLGAP5	-0.030397
CCDC80	-0.030338
WNT4	-0.030325
AURKA	-0.030288
PBK	-0.030242
TPX2	-0.030031
MELK	-0.029953
CRTAC1	-0.029872
NCAPH	-0.029845
PHF19	-0.029510
BUB1B	-0.029482
NCAPD2	-0.029467
DLX1	-0.029391
RAD51AP1	-0.029270
HIST2H2AB	-0.029088
CCL17	-0.029054
DCK	-0.029047
CENPH	-0.028902
F2RL3	-0.028847
HJURP	-0.028839
WDHD1	-0.028717
RAPGEF6	-0.028539
CLEC11A	-0.028424
PLK4	-0.028423
MCM2	-0.028230
GPR34	-0.028210
HIST2H2AC	-0.028194
FAM20C	-0.028189
HIRIP3	-0.028133
GINS3	-0.028118
SLC2A6	-0.028094
FBN2	-0.028070
INCENP	-0.027833
TNFRSF18	-0.027739
NCMAP	-0.027558
CX3CR1	-0.027476
SERINC2	-0.027356
OAS2	-0.027239
RAMP1	-0.027104
ST8SIA2	-0.027041
TICAM2	-0.026651
STMN1	-0.026616
ROR2	-0.026616
SFRP1	-0.026436
GPATCH11	-0.026395
CXCL14	-0.026230
IRF7	-0.026161
SERPINB2	-0.026158
KRT34	-0.026107
SMPDL3B	-0.025878
LMNB1	-0.025783
MS4A8	-0.025779
NAT8B	-0.025752
C14orf80	-0.025691
RASL11A	-0.025672
FAM111A	-0.025643
CCL5	-0.025559
CDCA5	-0.025549
POLD1	-0.025532
CTSW	-0.025431
CDC25C	-0.025418
MIS18BP1	-0.025324
UBE2T	-0.025282
TBX2	-0.025199
CLIC6	-0.025081
SH2D2A	-0.024834
PHF11	-0.024783
GPR183	-0.024711
TK1	-0.024711
TCF19	-0.024710
LTB	-0.024498
MCM7	-0.024456
GPC3	-0.024432
PKMYT1	-0.024260
SVEP1	-0.024251
CD3G	-0.024244
FGD2	-0.024174
SERPINB4	-0.024049
RNASE6	-0.023950
MRVI1	-0.023937
COL9A2	-0.023936
H1FX	-0.023896
HELB	-0.023781
CD180	-0.023774
SLAMF9	-0.023766
ATP12A	-0.023653
MYLK	-0.023584
CHAF1A	-0.023569
NDN	-0.023562
MYCL	-0.023553
LOX	-0.023535
NMRAL1	-0.023528
CENPA	-0.023395
FOLR2	-0.023280
ADAMTS18	-0.023265
C8orf46	-0.023250
IL18R1	-0.023231
RNASE2	-0.023225
GTSE1	-0.023182
ZWILCH	-0.023179
MAD2L1	-0.023124
TNFSF13B	-0.023095
KIAA1755	-0.023061
BMP3	-0.023041
DRP2	-0.022976
ZBTB46	-0.022919
RRM1	-0.022847
KRTDAP	-0.022795
RASGRP3	-0.022767
H2AFX	-0.022664
RPA2	-0.022663
ACTA2	-0.022660
KRT73	-0.022557
KANK4	-0.022532
TUBE1	-0.022513
ZCWPW1	-0.022513
SOSTDC1	-0.022495
SCG2	-0.022422
ANXA4	-0.022413
CRYBA4	-0.022362
RASL12	-0.022360
LMNB2	-0.022317
CLSPN	-0.022217
FOXM1	-0.022175
CD3D	-0.022160
TRIM62	-0.022160
FLYWCH2	-0.022127
VSIG4	-0.022046
DMP1	-0.021993
RPTN	-0.021881
ANKRD61	-0.021869
ZNF365	-0.021867
KIRREL3	-0.021838
SERPINI1	-0.021794
GDPD5	-0.021758
NDC80	-0.021756
PSMB9	-0.021683
NEURL1	-0.021613
KANK1	-0.021602
DIO3	-0.021597
DPP4	-0.021575
ESPL1	-0.021571
SEC14L2	-0.021518
FCHO1	-0.021463
PDGFRB	-0.021458
RGS14	-0.021446
ISG15	-0.021413
HPGD	-0.021377
PHGDH	-0.021348
RNASE1	-0.021345
YDJC	-0.021343
ADAM12	-0.021296
CDT1	-0.021287
GJB3	-0.021235
FGF1	-0.021202
CD3E	-0.021168
PRELP	-0.021144
PNLIP	-0.021133
MVD	-0.021129
PSMC3IP	-0.021118
CYP2S1	-0.021038
IL36RN	-0.021016
LRRC15	-0.020992
PTPRO	-0.020932
TONSL	-0.020930
CALN1	-0.020826
KRT86	-0.020770
C1orf112	-0.020735
HLA-DOA	-0.020689