!direction	-1
!num_genes	223
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Estradiol
!smiles	CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
!drugbank_id	DB00783
!pubchem_cid	5757
!cell_type	MCF-7 breast cancer cells - 24 Hours
!organism	human
!end_metadata
MME	-0.144071
ACKR3	-0.065854
FAM110B	-0.061480
EFEMP1	-0.061300
HCAR3	-0.059634
CERK	-0.057687
TNS3	-0.056581
CTGF	-0.056004
PDE8B	-0.055326
BLNK	-0.055170
TSPAN12	-0.053286
NELL2	-0.053160
ST6GALNAC5	-0.052547
TNFRSF11B	-0.052268
IL1R1	-0.051999
SASH1	-0.050112
PLK2	-0.049840
GRB14	-0.049352
CLSTN2	-0.048938
PMP22	-0.048474
SEMA3E	-0.048393
CTNND2	-0.048323
MATN2	-0.047214
UPK1A	-0.047144
LMCD1	-0.046704
PALMD	-0.046431
DRAM1	-0.046344
RPRM	-0.046093
HERC6	-0.044013
KIAA0922	-0.043724
NBEA	-0.043579
CSGALNACT1	-0.042774
SPON2	-0.042556
ELF5	-0.042005
RNASE4	-0.041967
RASGRP1	-0.040666
BIK	-0.040509
NR3C1	-0.040468
IER3	-0.039469
EFNA1	-0.039399
TIMP3	-0.038865
SLIT2	-0.038760
MCOLN3	-0.037842
CALML5	-0.037291
PSD3	-0.036725
ABCG1	-0.036410
SLC24A3	-0.036315
SIK1	-0.035768
KCNN2	-0.035405
ATP8A2	-0.035355
RHOBTB1	-0.035313
LAMB1	-0.035043
RNF144A	-0.034995
BAMBI	-0.034972
PARP11	-0.034840
LIMA1	-0.034764
ABLIM3	-0.034447
CEACAM6	-0.034388
CD55	-0.034204
PXDC1	-0.034098
KYNU	-0.034005
AUTS2	-0.033828
SPRY1	-0.033775
SERPINB1	-0.033633
ITPR1	-0.033586
NUPR1	-0.033289
ELF3	-0.033288
GAREM	-0.033246
ABCB4	-0.033066
HEY1	-0.032954
NUAK1	-0.032780
CAMK2N1	-0.032393
PTPN13	-0.032167
NLK	-0.031616
ANXA3	-0.031298
FAM105A	-0.031280
ATF3	-0.031126
CXCR4	-0.031080
CLGN	-0.031071
ATP8A1	-0.030833
GPR143	-0.030693
ARID5B	-0.030541
TMEM135	-0.030404
GALNT10	-0.030387
EFHD1	-0.030353
SEPP1	-0.030288
TOX3	-0.030236
CTF1	-0.029960
SH3BP4	-0.029800
ATP2B1	-0.029697
ERBB4	-0.029615
CSTA	-0.029354
TBX3	-0.029315
HIST1H2AE	-0.029221
CLMN	-0.029040
ZNF571	-0.029017
AMPD1	-0.028671
ZNF280D	-0.028606
FAM131A	-0.028598
HIST1H2BG	-0.028515
EFNB2	-0.028466
CBFA2T3	-0.028445
FGF13	-0.028403
HIST1H2AC	-0.028253
NEK11	-0.028182
FBN2	-0.028015
SYCP2	-0.027951
ARHGAP5	-0.027889
RAB26	-0.027792
ANXA2P1	-0.027524
ABCC5	-0.027274
ZDHHC7	-0.026932
SHROOM2	-0.026925
CLDN9	-0.026922
CPEB1	-0.026898
TSPAN1	-0.026878
BCAR3	-0.026841
SLC52A1	-0.026692
RFTN1	-0.026529
SPRY2	-0.026469
RND3	-0.026435
LDLRAD4	-0.026219
MBOAT2	-0.026218
GSAP	-0.026104
SIDT1	-0.026078
BMP7	-0.025853
N4BP3	-0.025788
SELENBP1	-0.025532
PCDH8	-0.025508
CCNG2	-0.025405
HIST1H2AM	-0.025314
MB	-0.025278
KLHL5	-0.025272
GABRR2	-0.024942
TPK1	-0.024930
TGFB3	-0.024852
PDZRN3	-0.024776
STON1	-0.024660
KIAA0513	-0.024615
AHNAK2	-0.024554
FAM134B	-0.024492
ARNT2	-0.024467
OSBP2	-0.024398
PLIN2	-0.024376
KCNJ8	-0.024353
ANG	-0.024018
TLE2	-0.023891
KIF3B	-0.023883
HDAC5	-0.023742
BTBD7	-0.023572
THBS1	-0.023570
GBP2	-0.023534
KRT23	-0.023442
SLMO1	-0.023405
KAL1	-0.023402
CTRC	-0.023329
CRY2	-0.023326
PLBD1	-0.023288
LARP6	-0.023256
PIN1P1	-0.023199
BCL6	-0.023167
MARK1	-0.023157
ACADSB	-0.023134
ERMAP	-0.023070
EYA2	-0.023005
LIN7A	-0.022991
FKBP10	-0.022961
PPAP2C	-0.022958
CLIC5	-0.022913
RMND1	-0.022908
FAM186A	-0.022905
RNF32	-0.022675
MSMB	-0.022635
FAM53B	-0.022582
CA11	-0.022535
GNAI1	-0.022466
UTRN	-0.022447
TGFBI	-0.022442
THNSL2	-0.022430
RPS6KC1	-0.022355
FOXO1	-0.022323
NVL	-0.022323
TESK2	-0.022220
TFAP4	-0.022160
KIAA1107	-0.022055
AMIGO2	-0.021983
MCTP1	-0.021960
MLLT3	-0.021932
FAM149A	-0.021921
NCAM2	-0.021901
TOM1	-0.021884
LPHN2	-0.021687
MSX2	-0.021666
ERBB2	-0.021663
ATP9A	-0.021640
CDH3	-0.021607
CEMIP	-0.021591
MAP4K4	-0.021586
LRRC8E	-0.021551
TGIF1	-0.021527
ZXDB	-0.021459
CBX6	-0.021457
SGCG	-0.021426
RAB20	-0.021352
CRIPT	-0.021333
HIST1H2AG	-0.021298
TFPI	-0.021293
RNF43	-0.021289
CDH18	-0.021288
GPR126	-0.021285
PCSK6	-0.021187
PTK6	-0.021159
LINC00963	-0.021142
HIST1H1C	-0.021110
HIST1H3H	-0.021030
LIMCH1	-0.020963
PODXL	-0.020960
LRRC49	-0.020948
DOCK4	-0.020888
HIST1H2BC	-0.020811
KLHL24	-0.020797
FYCO1	-0.020711
ZMIZ1	-0.020685