!direction	-1
!num_genes	238
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Estradiol
!smiles	CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
!drugbank_id	DB00783
!pubchem_cid	5757
!cell_type	Uterus - single injection of 400 ug/kg - 2 Hours after treatment
!organism	mouse
!end_metadata
RPS19	-0.156835
GAS1	-0.100982
RPL7	-0.089980
ID2	-0.086787
HK1	-0.085062
APCDD1	-0.076815
RPS26	-0.076305
LAPTM4A	-0.074616
LSP1	-0.073633
RPS10	-0.073597
DCN	-0.070316
RPS5	-0.060317
APP	-0.058529
PLAT	-0.053587
RPS15A	-0.053462
RPL21	-0.052224
IFITM3	-0.051976
PLP2	-0.051714
KCTD12	-0.050451
CTDSP2	-0.050263
WDR92	-0.049487
HOXA11	-0.049107
LUM	-0.048206
S100A6	-0.047623
RPL10	-0.046459
SPARCL1	-0.046220
PLAC8	-0.045762
TUBB	-0.045301
FZD2	-0.044125
MYADM	-0.043646
PABPC1	-0.043421
MMP14	-0.043164
TSC22D1	-0.043111
PPIA	-0.043014
TUBA1A	-0.042349
GNB2L1	-0.041877
RPL28	-0.039804
RGS2	-0.039692
RPL7A	-0.039426
MYLK	-0.039370
RAC1	-0.039172
YPEL3	-0.038708
RPL3	-0.037433
RIN2	-0.037131
RPLP0	-0.037037
ISLR	-0.036976
SESN1	-0.036489
MYL12A	-0.036362
SOX17	-0.036233
ACAA2	-0.036092
TPT1	-0.035590
COL5A2	-0.035452
MXD4	-0.035291
LTBP4	-0.034908
NPM1	-0.034785
NREP	-0.034728
COL3A1	-0.034479
TXNIP	-0.033605
RPS12	-0.033464
MSX1	-0.033300
RPS11	-0.033300
MARVELD1	-0.033011
FAM101B	-0.032909
PGRMC1	-0.032892
IGFBP6	-0.032757
RPS3	-0.032592
SERPING1	-0.032501
RPL10A	-0.032140
FMO1	-0.031852
EID1	-0.031547
PNRC2	-0.031295
PRKCDBP	-0.031147
NDP	-0.031101
RNF167	-0.030683
B2M	-0.030676
LY6E	-0.030577
GABARAPL1	-0.030291
ARL6IP1	-0.030278
YBX1	-0.030216
COL1A1	-0.030140
CTSD	-0.030105
CNN3	-0.029802
MYH11	-0.029020
PENK	-0.028862
EEF2	-0.028736
DSTN	-0.028488
CST3	-0.028332
IGFBP3	-0.028288
ARHGEF25	-0.028218
S100A10	-0.027831
RPS24	-0.027650
SOX4	-0.027474
RABAC1	-0.027255
MAF1	-0.026910
ITM2B	-0.026865
RARRES2	-0.026838
PPIB	-0.026765
PTCH1	-0.026745
GNAI3	-0.026580
RAD21	-0.026532
LBP	-0.026440
SFRP2	-0.026022
RPL5	-0.025649
TXN	-0.025541
ISOC1	-0.025474
WFDC2	-0.025382
COL4A2	-0.025363
THY1	-0.025335
H1F0	-0.025328
POSTN	-0.025294
REV3L	-0.025103
LMO4	-0.024858
SDPR	-0.024623
DBP	-0.024589
ATPIF1	-0.024455
ANXA5	-0.024379
TCF4	-0.024160
MGP	-0.024131
ST5	-0.023963
ATP5A1	-0.023923
CCNB2	-0.023901
ANAPC11	-0.023452
COL1A2	-0.023332
TPI1	-0.023064
AKR1A1	-0.022995
LTA4H	-0.022969
COL6A1	-0.022930
H2AFZ	-0.022701
MDK	-0.022657
PDHA1	-0.022485
SLC25A4	-0.022248
ECH1	-0.022010
SERINC3	-0.021970
EFNB2	-0.021633
SH3BGRL	-0.021085
TAGLN	-0.021062
ANXA1	-0.021026
SERPINB6	-0.020926
BTG1	-0.020924
RAMP1	-0.020709
NDUFB5	-0.020660
GSTP1	-0.020620
TGFBI	-0.020612
LGALS1	-0.020311
ERGIC3	-0.020198
RPL27A	-0.020057
CALB1	-0.019978
TLE1	-0.019975
GDF10	-0.019926
TNFAIP8	-0.019862
DPT	-0.019861
CPE	-0.019798
PLTP	-0.019790
APOE	-0.019609
RNASE4	-0.019600
PLS3	-0.019514
TMEM176B	-0.019500
HDC	-0.019470
TUBA1B	-0.019311
COX7A2L	-0.019178
ITGB1	-0.019173
IL10RB	-0.019132
VKORC1	-0.019060
GSTO1	-0.019036
PAPSS1	-0.018980
ZFP36L1	-0.018890
RERE	-0.018857
RECK	-0.018852
NPNT	-0.018716
HIST1H1C	-0.018529
PCP4	-0.018459
ACTA1	-0.018425
COL4A1	-0.018396
PTGER4	-0.018338
TSPO	-0.018267
ATP5C1	-0.018261
WLS	-0.018118
SLMAP	-0.017986
CTSV	-0.017979
PSMC6	-0.017978
FSTL1	-0.017957
DAP	-0.017896
DBNDD2	-0.017784
VPS28	-0.017771
EIF4A2	-0.017725
MCAM	-0.017701
PCYOX1	-0.017675
GPC3	-0.017658
PPAP2B	-0.017646
DYNC1I1	-0.017519
GPAM	-0.017493
CBX6	-0.017493
SPARC	-0.017375
TGIF1	-0.017370
NUMA1	-0.017351
WDR6	-0.017350
GTF2I	-0.017212
CAPNS1	-0.017187
CD63	-0.017183
GAA	-0.017133
HCFC1R1	-0.016995
RPL6	-0.016982
RPL18	-0.016951
ZFAND6	-0.016871
C12orf57	-0.016860
ZBTB16	-0.016730
PSD	-0.016717
DNAJC10	-0.016662
CNPY2	-0.016600
FAM171A1	-0.016578
LAMP2	-0.016509
TRIM25	-0.016434
KRT19	-0.016375
ILK	-0.016361
HDAC5	-0.016317
RPS17	-0.016305
CLDN5	-0.016266
TBL1XR1	-0.016150
KITLG	-0.016127
PPIC	-0.016085
CPNE3	-0.016026
THRSP	-0.015991
STMN1	-0.015991
GPI	-0.015979
RPS27A	-0.015973
WNT5A	-0.015968
NFIX	-0.015966
ACTA2	-0.015898
FAM8A1	-0.015670
PHPT1	-0.015669
CITED2	-0.015640
CSRP2	-0.015625
TCF21	-0.015613
KCNJ8	-0.015611
AIMP1	-0.015600
VPS26B	-0.015562
CTNNB1	-0.015539
IRF6	-0.015475