!direction	-1
!num_genes	324
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Doxycycline
!smiles	CC1C2C(C3C(C(=O)C(=C(N)O)C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)N(C)C)O
!drugbank_id	DB00254
!pubchem_cid	5281011
!cell_type	C33KD2 cells
!organism	human
!end_metadata
BIRC8	-0.093563
SAGE1	-0.063423
CHCHD10	-0.061318
ZNF483	-0.059218
CRISP3	-0.057229
TRMT112	-0.051628
CLCA1	-0.051143
KIN	-0.050620
ACADS	-0.046432
TYMS	-0.045870
GLI1	-0.045523
ARG1	-0.044817
HIST1H4B	-0.043780
SPTSSB	-0.043121
SUSD5	-0.042081
CLIC3	-0.041936
C10orf25	-0.041320
FGF23	-0.041199
C11orf85	-0.040933
SLC22A14	-0.040709
NOD2	-0.040654
KRT8P41	-0.039591
CD72	-0.038287
LOC100996579	-0.038029
KCNS3	-0.037796
CCNE2	-0.037213
HIST1H4C	-0.036704
TMEM123	-0.036684
SLC38A4	-0.036444
LMNTD1	-0.036350
IL12B	-0.035938
TMEM129	-0.035789
LINC01192	-0.035746
RAET1E	-0.035521
GNPDA1	-0.034998
USP27X	-0.034965
PLD6	-0.034901
USP11	-0.034772
LOC100507468	-0.034626
BEX1	-0.034499
DHX29	-0.034480
SP8	-0.033585
C3orf20	-0.032953
VASP	-0.032639
ZNF772	-0.032593
BAI1	-0.032157
IGKV1D-8	-0.032044
CDK2AP1	-0.031989
LPAR1	-0.031811
LOC100996425	-0.031651
CBR3-AS1	-0.031508
FBXO38	-0.031211
CPED1	-0.030944
CAMKV	-0.030761
CHIT1	-0.030628
BEX2	-0.030611
NCAM2	-0.030568
CACNG6	-0.030522
SUMO3	-0.030470
HAND2	-0.030466
RTN2	-0.030364
CCL18	-0.030268
AP4S1	-0.030111
RAB38	-0.029814
DMKN	-0.029803
ZNF22	-0.029780
PADI1	-0.029743
DDX6	-0.029735
SMARCD1	-0.029677
CDIPT-AS1	-0.029670
EDIL3	-0.029589
GPR85	-0.029553
MDK	-0.029441
LOC100130256	-0.029358
CHD8	-0.029240
PPDPF	-0.029201
MAGEA10	-0.029150
ZBTB38	-0.029050
TMC3	-0.028884
HIST1H1E	-0.028659
MYO3A	-0.028623
UBE2M	-0.028578
SNORA76C	-0.028526
ADORA2B	-0.028519
IGKV1D-13	-0.028426
SLC6A12	-0.028390
KCNF1	-0.028102
SAMSN1	-0.028067
PCBP3	-0.027884
NDUFAF7	-0.027793
IGDCC3	-0.027571
LPGAT1	-0.027520
WBSCR28	-0.027317
FLJ37201	-0.027218
MUC1	-0.027164
GNAI2	-0.027110
SRGN	-0.026966
OGDHL	-0.026833
SHCBP1L	-0.026833
FADS1	-0.026685
LOC100130156	-0.026493
PTPLAD2	-0.026483
DCT	-0.026475
APOB	-0.026367
KEL	-0.026360
LINC00116	-0.026278
ANKRD34A	-0.025997
LUZP2	-0.025872
EOMES	-0.025555
NR4A3	-0.025487
H1F0	-0.025461
FBXL12	-0.025293
FAM213A	-0.025260
CRABP2	-0.025213
DVL2	-0.025192
PNRC1	-0.025178
ASB11	-0.025035
ZNF362	-0.025023
PPAP2A	-0.024939
EFCAB2	-0.024664
ZNF580	-0.024654
DMRT2	-0.024622
MEIS2	-0.024593
LINC00844	-0.024545
FADS6	-0.024495
LOC100507311	-0.024408
PABPC4	-0.024397
EMC6	-0.024309
MYL10	-0.024264
FRAT1	-0.024183
MPI	-0.024157
C12orf42	-0.024154
KRT5	-0.024009
DNM2	-0.024009
CD300LD	-0.023906
HORMAD1	-0.023896
EIF2B5	-0.023864
INHBB	-0.023834
TMEM63B	-0.023492
CBX3	-0.023447
HIST1H1C	-0.023423
C7orf31	-0.023344
PRR14	-0.023315
GINS1	-0.023280
NUCKS1	-0.023180
TM4SF19	-0.023134
LOC441052	-0.023111
LOC727916	-0.023058
PVRL2	-0.023055
VBP1	-0.022996
LOC100506242	-0.022952
REPIN1	-0.022945
PLEK2	-0.022929
CLEC4C	-0.022924
CST9L	-0.022916
PP12708	-0.022815
ECSCR	-0.022749
GAS6	-0.022720
GNG11	-0.022634
OR1A1	-0.022595
AKR1E2	-0.022567
ZKSCAN7	-0.022532
CYBA	-0.022462
LGR5	-0.022448
ACTR3	-0.022429
PIGP	-0.022336
HAUS4	-0.022321
PALLD	-0.022287
TAF13	-0.022257
AAED1	-0.022257
KIAA1652	-0.022233
EBAG9	-0.022163
ELAC1	-0.022148
LOC101927811	-0.022118
KRT6C	-0.022009
HIST1H4D	-0.021960
GPR35	-0.021956
PDE8B	-0.021909
HBP1	-0.021861
SQRDL	-0.021854
DUSP3	-0.021853
EFCAB6	-0.021837
AMZ1	-0.021802
PRO2852	-0.021781
SMNDC1	-0.021762
CTGF	-0.021760
ENDOU	-0.021754
RNF220	-0.021683
MARCKS	-0.021674
LOC283454	-0.021668
LRRTM3	-0.021642
TAC1	-0.021625
PNPLA4	-0.021525
SRPK1	-0.021496
SUGT1P3	-0.021469
PHC1	-0.021437
MFSD3	-0.021387
SCGB1D1	-0.021380
PNRC2	-0.021368
DACT2	-0.021349
ZNF701	-0.021330
LHX6	-0.021295
SLC26A8	-0.021272
LOC90834	-0.021216
COMT	-0.021215
QTRT1	-0.021213
THBS2	-0.021187
SALL1	-0.021123
CADM2	-0.021109
ADCK1	-0.021094
CNTFR	-0.021084
FAM222B	-0.021080
TMC5	-0.021037
CAPN3	-0.021036
GAFA2	-0.021015
NSA2	-0.020997
EHHADH	-0.020917
KLRG1	-0.020871
CPA2	-0.020847
DCTN6	-0.020753
L1TD1	-0.020675
C20orf141	-0.020675
NUDT10	-0.020626
CCL2	-0.020609
SETD6	-0.020607
ZNF503-AS1	-0.020556
HPCA	-0.020515
EML1	-0.020462
NNT	-0.020454
CEP41	-0.020432
LOC100130264	-0.020427
FBN1	-0.020412
NGFRAP1	-0.020400
KCNJ16	-0.020397
TCN1	-0.020393
PLEKHG4	-0.020374
POLR2I	-0.020361
HDDC3	-0.020361
RAET1K	-0.020357
LTBR	-0.020355
C10orf67	-0.020322
LTBP1	-0.020316
PKIB	-0.020307
EIF1B-AS1	-0.020280
LAIR1	-0.020254
SEC31B	-0.020208
INSL4	-0.020199
SLC34A3	-0.020155
DLAT	-0.020148
ALB	-0.020131
SYNPR	-0.020096
SIDT1	-0.020062
LRRCC1	-0.020003
GABARAP	-0.019959
XDH	-0.019943
DIRAS3	-0.019898
SPANXD	-0.019875
FAM134B	-0.019867
CYTL1	-0.019865
DCP1B	-0.019843
ARHGEF16	-0.019814
PLEKHA7	-0.019803
CLDND2	-0.019740
LCLAT1	-0.019739
PCDHA11	-0.019715
ARNTL2	-0.019703
ATXN2L	-0.019691
CENPA	-0.019647
TTTY4C	-0.019647
NEFH	-0.019647
TIMM21	-0.019644
CNGA1	-0.019636
CYP27A1	-0.019634
HOXC11	-0.019633
SPTY2D1-AS1	-0.019618
HIST1H4H	-0.019598
PDE4A	-0.019590
FKBP11	-0.019584
C7orf60	-0.019577
SLCO1A2	-0.019566
SDPR	-0.019545
A2M	-0.019542
KIAA0319L	-0.019482
CBLC	-0.019449
CPXM2	-0.019438
CHST12	-0.019428
RAB40B	-0.019421
PDE6H	-0.019414
CALM3	-0.019413
TMEM45B	-0.019368
KDM4D	-0.019360
GDF5	-0.019316
RTN3	-0.019274
CNRIP1	-0.019235
LARS2	-0.019227
CRLF2	-0.019224
AMDHD1	-0.019183
PROSER2-AS1	-0.019154
HS3ST3A1	-0.019135
RARB	-0.019126
C3orf18	-0.019115
KLHL24	-0.019078
DPP8	-0.019070
NSG1	-0.019055
GRP	-0.019005
RWDD2B	-0.019003
PRAMEF17	-0.018976
ZNF594	-0.018959
RAB42	-0.018796
ZSWIM2	-0.018770
GNA13	-0.018754
PBX1	-0.018665
LOC100128816	-0.018651
GPR19	-0.018599
AGPAT3	-0.018565
DUSP6	-0.018551
C11orf87	-0.018534
FST	-0.018531
GMPR	-0.018530
PSD	-0.018492
TYRP1	-0.018470
CHST15	-0.018454
TMED7	-0.018424
WT1	-0.018422