!direction	-1
!num_genes	229
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Irinotecan
!smiles	CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
!drugbank_id	DB00762
!pubchem_cid	60838
!cell_type	stomach
!organism	rat
!end_metadata
UPK1B	-0.069541
ATP8B1	-0.053123
GPM6A	-0.050812
PTF1A	-0.050738
CCL11	-0.047955
UBN2	-0.041635
SLC39A8	-0.041333
DDX6	-0.040202
ASPRV1	-0.039808
SPRR3	-0.038272
BHLHA15	-0.037985
FAM46C	-0.037687
ZBTB41	-0.037089
CYP19A1	-0.036748
PLCXD3	-0.035065
SPINK5	-0.034848
PROC	-0.034753
MIA3	-0.034267
HDC	-0.033642
PRKAA2	-0.033436
MSLN	-0.032453
ACP1	-0.031842
REG3A	-0.031671
TMED5	-0.030946
TMED6	-0.030627
ARHGAP5	-0.030222
STON2	-0.030140
ITGA1	-0.030076
KRT78	-0.030027
ENTPD5	-0.029377
SLPI	-0.029296
BNC1	-0.028962
TPR	-0.028831
WDFY1	-0.028826
HSD17B7	-0.028816
MIS12	-0.028724
PYCR1	-0.028300
GFM1	-0.027445
MRC1	-0.027346
TMEM258	-0.027240
GGH	-0.027091
CDC73	-0.026953
HSD17B3	-0.026931
NIPBL	-0.026807
STEAP4	-0.026660
CFB	-0.026561
CCND2	-0.026372
TNFAIP8	-0.026211
RNF152	-0.026146
EVI5	-0.026094
LPP	-0.025985
CCKAR	-0.025743
ZDHHC20	-0.025637
FASTKD5	-0.025593
LPAR6	-0.025495
LYZ	-0.025403
VNN1	-0.025382
EMG1	-0.025363
WASF2	-0.025311
RAPGEF2	-0.025000
COX16	-0.024924
RAB27A	-0.024626
ALDH6A1	-0.024618
VPS37A	-0.024592
POSTN	-0.024542
CD53	-0.024530
ARID4A	-0.024424
ID3	-0.024309
PON3	-0.024276
FAM3B	-0.024180
AASS	-0.024150
ALOX5AP	-0.024065
HIST1H2BG	-0.024043
CHORDC1	-0.023842
SERPINI1	-0.023817
IMP3	-0.023790
FGFBP1	-0.023745
SCFD1	-0.023722
CPNE3	-0.023697
KPRP	-0.023672
USO1	-0.023644
CFH	-0.023613
FAR1	-0.023423
SLC18A2	-0.023346
LOX	-0.023292
UXT	-0.023225
TET2	-0.023171
CPED1	-0.023091
SF3B6	-0.023051
CHD1	-0.022973
RPRM	-0.022945
SLC38A5	-0.022838
COA4	-0.022833
CRABP2	-0.022735
RND3	-0.022710
COL4A3BP	-0.022699
BMPR1A	-0.022551
KIF5B	-0.022531
CASP3	-0.022473
MTRF1	-0.022472
VPS41	-0.022438
DUOX2	-0.022438
KLK8	-0.022238
H2AFJ	-0.022237
GMFG	-0.022183
SERP1	-0.022173
OSTC	-0.022063
ANKRD37	-0.022056
ELOVL6	-0.022039
SHH	-0.022023
GRP	-0.022011
SLC4A4	-0.021895
ADHFE1	-0.021846
TIMM17A	-0.021827
SUMO1	-0.021804
TSN	-0.021776
BCCIP	-0.021756
MSRB1	-0.021683
ABCC4	-0.021679
SF3B5	-0.021667
FCHSD2	-0.021629
ADK	-0.021613
PHIP	-0.021563
LY96	-0.021486
KLK3	-0.021466
IWS1	-0.021401
WDR92	-0.021384
CCR1	-0.021344
WDR61	-0.021322
GNMT	-0.021312
PSMA2	-0.021308
ARG1	-0.021294
MED21	-0.021204
PRKAR2B	-0.021165
AKIRIN2	-0.021121
MRPL42	-0.021117
ARFRP1	-0.021044
DNAJB11	-0.021037
PPP6R3	-0.021031
APOA1	-0.021022
DTWD2	-0.020922
TMEM27	-0.020916
DMKN	-0.020908
SMU1	-0.020843
PNLIPRP1	-0.020779
ATP6V1H	-0.020748
F13A1	-0.020746
ROMO1	-0.020698
MRPS28	-0.020603
HRSP12	-0.020563
PGGT1B	-0.020527
CNFN	-0.020505
PPP1R12A	-0.020457
EFCAB14	-0.020375
PPARG	-0.020375
KRT12	-0.020351
SNRPD1	-0.020338
HDHD3	-0.020322
CDK7	-0.020254
DENND5B	-0.020233
SERPINB12	-0.020209
ARID4B	-0.020188
GLIPR1	-0.020183
SRP19	-0.020170
TMEM45B	-0.020137
DPM3	-0.020132
TRIM25	-0.020054
CETN2	-0.020037
EMCN	-0.019995
SMIM7	-0.019984
MAGT1	-0.019940
XRN2	-0.019900
ERGIC2	-0.019872
TAB2	-0.019752
STOML2	-0.019752
ARL6IP5	-0.019726
PDGFRA	-0.019720
PAPOLA	-0.019716
SSR2	-0.019695
NUDCD2	-0.019677
PBDC1	-0.019676
SEC24D	-0.019661
LSM10	-0.019631
ATP5L	-0.019610
LRP6	-0.019504
GDAP2	-0.019484
ABCE1	-0.019452
PSMD14	-0.019441
SRP9	-0.019438
SPCS2	-0.019424
RPA3	-0.019352
EML4	-0.019295
SDF4	-0.019188
ATRX	-0.019116
SERPING1	-0.019063
NEDD1	-0.019054
SSSCA1	-0.019026
ENPP3	-0.019023
TMEM161B	-0.019004
ELP2	-0.018997
SEC22A	-0.018933
THRSP	-0.018868
ZNF451	-0.018862
BDH2	-0.018847
UGDH	-0.018800
ELOVL4	-0.018800
DHPS	-0.018737
CADPS2	-0.018731
C1GALT1	-0.018691
SCG5	-0.018667
ATPIF1	-0.018657
LYRM4	-0.018643
PPAT	-0.018636
CA5B	-0.018634
ATXN7	-0.018604
RASA1	-0.018586
MED8	-0.018569
PTDSS1	-0.018557
RRP8	-0.018452
HEATR5A	-0.018412
GSTA3	-0.018369
UNC50	-0.018354
C1QA	-0.018303
TCTEX1D2	-0.018293
SLC16A7	-0.018284
ERCC6L2	-0.018246
ITGB7	-0.018227
PTHLH	-0.018215
EBP	-0.018212