!direction	-1
!num_genes	233
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Heroin
!smiles	CC(=O)OC1C=CC2C3CC4=C5C2(C1OC5=C(C=C4)OC(=O)C)CCN3C
!drugbank_id	DB01452
!pubchem_cid	5462328
!cell_type	striatum, day 13 withdrawal
!organism	mouse
!end_metadata
PMCH	-0.261079
SLC6A13	-0.118738
SLC13A4	-0.101164
SLC6A12	-0.099551
C1QL2	-0.093408
PTGDS	-0.083588
S100A5	-0.083216
STK32C	-0.082457
TNNT1	-0.076428
GBX2	-0.068053
ZIC1	-0.066227
PRKCD	-0.064022
HLA-DQA1	-0.057712
ND5	-0.056992
GAL	-0.056674
S100B	-0.054385
ISL1	-0.053504
IGF2	-0.053265
IGSF1	-0.052928
SERPING1	-0.052512
C2	-0.051644
AEBP1	-0.050074
HSPA5	-0.046870
SLC17A6	-0.046784
THBD	-0.046665
RPS25	-0.046298
CALB2	-0.045288
TSR3	-0.044448
CRYAB	-0.044277
RGS16	-0.044099
AGT	-0.043206
FAM180A	-0.041817
PRR7	-0.040524
H1F0	-0.040197
HLA-DRB5	-0.040130
CD74	-0.040111
CHPF	-0.039836
KLK6	-0.039503
SLC6A3	-0.038763
DOK3	-0.037208
OGN	-0.036388
PAM16	-0.036126
KLK8	-0.035985
SLC22A6	-0.035881
TOP2B	-0.035540
EMP2	-0.034443
CLDN5	-0.034306
OXT	-0.034201
AVP	-0.034084
FIBCD1	-0.033690
GLUL	-0.033530
LIN7C	-0.033469
HMGCS2	-0.033269
GPR17	-0.033206
ST13	-0.033199
UNC5B	-0.032970
DCN	-0.032699
KLHL13	-0.032422
ITIH3	-0.032390
EGR2	-0.031892
PTGIS	-0.031344
TATDN2	-0.031266
YWHAE	-0.031229
SLC3A2	-0.031104
ECEL1	-0.031009
COX7B	-0.030593
VPS4B	-0.030433
S100A8	-0.030220
TTYH2	-0.029862
STK32B	-0.029650
GATM	-0.029416
RESP18	-0.029319
NDN	-0.029236
SLC12A5	-0.028803
S100A6	-0.028699
NTNG1	-0.028402
SP8	-0.028229
CACYBP	-0.028225
VAT1L	-0.028161
IDI1	-0.027898
SLC47A1	-0.027628
USMG5	-0.027256
ITIH2	-0.027101
CCT5	-0.027059
CGA	-0.026687
AGPAT3	-0.026494
SPP1	-0.026322
PHYHIPL	-0.026143
NGB	-0.025663
PTPN1	-0.025404
S100A10	-0.025286
FOXC2	-0.025115
SLC25A4	-0.025100
EMP3	-0.024940
PET100	-0.024651
RANBP3L	-0.024640
RET	-0.024506
GJB2	-0.024414
FAM196B	-0.024291
BGN	-0.024268
TMEFF1	-0.024076
HIST1H2BM	-0.024037
CTSS	-0.023579
PFKFB3	-0.023259
SEPP1	-0.023184
RASD2	-0.023142
H3F3C	-0.023004
CCT7	-0.022686
SDF2L1	-0.022585
HIST1H2BF	-0.022255
SMARCA5	-0.022239
LRP1	-0.022218
PLA2G7	-0.022115
HIST1H1C	-0.022039
VAPB	-0.022024
OMP	-0.022005
SUGT1	-0.021907
ITGA10	-0.021862
HEBP1	-0.021861
GPX3	-0.021851
HAPLN2	-0.021743
SLC27A3	-0.021593
B9D2	-0.021528
IDO1	-0.021219
PAM	-0.021160
C15orf59	-0.021028
YWHAQ	-0.020846
OTUD6B	-0.020803
EFNB1	-0.020760
CDC123	-0.020738
HIST4H4	-0.020677
ZFP1	-0.020648
RPE65	-0.020645
TSPYL4	-0.020505
NONO	-0.020501
ACTB	-0.020472
C1orf110	-0.020470
FMOD	-0.020444
NKX6-2	-0.020181
GAL3ST1	-0.020089
FRMD7	-0.020087
HIST2H4B	-0.020053
PCNA	-0.019838
HIST1H2BN	-0.019792
NKX2-1	-0.019757
FAM103A1	-0.019714
HLA-DQB1	-0.019700
SNAPC1	-0.019629
RSPRY1	-0.019526
ZBTB8OS	-0.019454
CDHR1	-0.019438
ASGR1	-0.019424
GABRA3	-0.019419
HSPB1	-0.019379
NEU2	-0.019373
TEX2	-0.019188
SOX2	-0.019112
SNCG	-0.018848
ESYT3	-0.018829
NOL7	-0.018694
GPR68	-0.018670
RAPGEF3	-0.018631
PDIA4	-0.018570
FIG4	-0.018493
GAL3ST4	-0.018433
TMIE	-0.018395
EIF4EBP1	-0.018312
SCARF2	-0.018260
WNT2	-0.018256
HOXB8	-0.018235
C17orf70	-0.018204
GPC3	-0.018128
C7orf55	-0.018063
PMPCB	-0.018062
ATP6V1C2	-0.017975
AMIGO2	-0.017930
FRS3	-0.017923
HIST1H2AM	-0.017887
EVPL	-0.017772
HIST1H2BK	-0.017764
ITGB4	-0.017711
HIST1H4K	-0.017690
MMP14	-0.017673
C8B	-0.017663
SCRG1	-0.017661
MCCC1	-0.017623
ARL4D	-0.017617
SLC35D3	-0.017586
PDLIM2	-0.017555
NPY2R	-0.017374
SPHK1	-0.017369
NGFR	-0.017340
FHDC1	-0.017332
BDH2	-0.017323
HSD11B1	-0.017299
OSBPL11	-0.017256
CYP2S1	-0.017239
GJB6	-0.017224
ADRBK1	-0.017193
FRMD4B	-0.017092
PSPC1	-0.016952
TSPAN3	-0.016916
BFSP2	-0.016822
RXFP3	-0.016814
IL18BP	-0.016798
TXNDC12	-0.016791
HIST1H2BL	-0.016772
RGS14	-0.016735
DDAH2	-0.016726
SYTL4	-0.016697
HIST1H2BG	-0.016670
SPRY2	-0.016658
BICC1	-0.016562
DGKK	-0.016449
UACA	-0.016441
SPON1	-0.016415
FOXA1	-0.016345
BCAS2	-0.016322
ADCY8	-0.016320
IRS2	-0.016311
RNF166	-0.016284
DYNLL2	-0.016261
TUBB2B	-0.016071
ATF5	-0.016064
MRPL18	-0.016021
NUPR1	-0.015979
HIST1H3I	-0.015943
P2RY1	-0.015870
RPL18A	-0.015798
PCDHB16	-0.015681
EDF1	-0.015675
LAPTM4B	-0.015619
ADAMTS2	-0.015611