!direction	-1
!num_genes	248
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	MEK inhibitor (MEKi : AZD6244)
!smiles	CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
!pubchem_cid	10127622
!cell_type	SW480 cancer cells
!organism	human
!end_metadata
DUSP6	-0.181157
EGR1	-0.122142
APCDD1	-0.074147
WNT5A	-0.063364
ASAP2	-0.061909
TNS4	-0.058267
DNAJB6	-0.057729
IER5	-0.056571
LINC00341	-0.056200
C16orf54	-0.055765
EDAR	-0.055507
DNMBP	-0.053944
EN2	-0.053911
FGF19	-0.053325
ETV5	-0.052733
NET1	-0.052227
IRF2BPL	-0.051813
DCUN1D3	-0.049482
ETV3	-0.049398
HOXB7	-0.048981
TNFRSF1B	-0.048958
ADORA2B	-0.046142
IER3	-0.045765
NDP	-0.044933
SMURF2	-0.044346
ALDH1A3	-0.044336
HOXA1	-0.042685
UBE2E3	-0.041338
MGAT5	-0.039484
NGFRAP1	-0.039266
SLC38A2	-0.039163
ILF2	-0.038930
MYL12A	-0.038822
TIPARP	-0.038470
PHLDA1	-0.038064
ID2	-0.037780
TLE3	-0.037697
ZIC2	-0.037231
IRS2	-0.037087
EPHA2	-0.036954
SLC39A10	-0.035899
PMEPA1	-0.035364
IER2	-0.035198
SPIN4	-0.035006
ARHGAP12	-0.034914
SAT1	-0.034558
PARP4	-0.034453
POC1B	-0.034424
LOC100130468	-0.033923
CDCA7L	-0.033860
HMGA1	-0.033673
IL17RD	-0.033386
TOPBP1	-0.033382
ORAI3	-0.033335
EVA1C	-0.033193
NGFR	-0.033013
SCAF8	-0.032979
CCND1	-0.032821
OSBPL3	-0.032204
DHCR24	-0.032053
GPRC5A	-0.031839
CTDSP1	-0.031805
SPRY2	-0.031667
SEPHS2	-0.031651
CPSF3	-0.031304
TBC1D4	-0.031282
SMARCD2	-0.031148
KLK6	-0.031065
SMNDC1	-0.031016
UBLCP1	-0.030942
LIMS3	-0.030805
DYNLL1	-0.030534
MCM4	-0.030528
AFAP1L2	-0.030513
TINAGL1	-0.030175
METTL9	-0.030103
B4GALT5	-0.030045
ALDH9A1	-0.029910
NIF3L1	-0.029781
RNF43	-0.029693
COX3	-0.029337
ELK3	-0.029176
APOBEC3C	-0.029038
AATF	-0.028853
KCNJ5	-0.028749
CPOX	-0.028655
IRF2BP2	-0.028513
ANXA6	-0.028175
IGFBP3	-0.027949
CALR	-0.027616
HOXB5	-0.027576
HSD17B11	-0.027542
PALD1	-0.027279
GPR137B	-0.027189
DHRS3	-0.027113
EIF5A2	-0.027088
DEPDC7	-0.027049
S100A16	-0.026642
PPP1CC	-0.026592
SNX9	-0.026577
IGFBP4	-0.026521
ZWINT	-0.026401
CLDN11	-0.026332
TMEM123	-0.026280
CTR9	-0.026260
PCBP1	-0.026214
LMNB1	-0.026159
SLC1A5	-0.025969
LASP1	-0.025947
IRS1	-0.025772
HOXA3	-0.025584
ARL4C	-0.025498
MRPL3	-0.025453
MYEOV	-0.025389
UNC50	-0.025314
TGFBI	-0.025244
PAX6	-0.025232
TMX3	-0.025203
GALNT4	-0.024970
HOXB8	-0.024593
KIAA0907	-0.024477
TIAM1	-0.024424
SYPL1	-0.024378
GLRX	-0.024360
CHCHD3	-0.024239
SLC16A1	-0.024233
SPRY4	-0.024109
RASSF3	-0.023754
ARHGEF3	-0.023747
PRF1	-0.023698
RAP2C	-0.023516
RACGAP1	-0.023501
MALL	-0.023450
HDAC4	-0.023438
CDC25B	-0.023437
HOXB3	-0.023409
PIM1	-0.023372
GSTO1	-0.023346
CHMP5	-0.023318
SHC1	-0.023277
SPRED2	-0.023183
CHST11	-0.023084
NDUFB3	-0.023007
CRY1	-0.022970
ITGB5	-0.022824
FANCL	-0.022814
ITGA6	-0.022791
KDM7A	-0.022673
FAT1	-0.022627
SH3KBP1	-0.022602
CKS1B	-0.022544
PTCH1	-0.022364
HOXB6	-0.022356
HIST1H2BK	-0.022353
CLCC1	-0.022343
APP	-0.022266
MRGBP	-0.022177
SLC7A7	-0.021967
HOXA10	-0.021889
SOWAHC	-0.021888
BMP7	-0.021705
ARHGEF18	-0.021702
JHDM1D-AS1	-0.021668
CTDSP2	-0.021618
SLC16A6	-0.021579
GPSM2	-0.021544
CXCR4	-0.021486
ACN9	-0.021481
SEC14L1	-0.021404
FAM102B	-0.021354
GJB1	-0.021331
SHQ1	-0.021253
CNEP1R1	-0.021246
SAV1	-0.021194
RAD21	-0.021162
SLC48A1	-0.021114
TMEM126A	-0.021048
HIF1A	-0.020799
SPRY4-IT1	-0.020756
UBA2	-0.020672
IRF2	-0.020666
NANOS1	-0.020549
RNF220	-0.020508
SERINC5	-0.020356
GLRX5	-0.020252
YWHAQ	-0.020215
AP1S2	-0.020205
FAM134A	-0.020074
SERPINE1	-0.019956
ZCCHC24	-0.019885
TMEM243	-0.019871
PHB2	-0.019854
DUSP5	-0.019844
B3GNT2	-0.019754
HSPE1	-0.019711
FUCA1	-0.019687
LPCAT2	-0.019681
JTB	-0.019675
TIMP1	-0.019642
APOBEC3B	-0.019574
DHX15	-0.019563
PDP1	-0.019451
MRPS24	-0.019436
LOC100288675	-0.019396
METAP1	-0.019384
GOLPH3L	-0.019376
HNRNPUL1	-0.019357
PTPRJ	-0.019303
TXNDC12	-0.019290
TNFRSF1A	-0.019208
FAM8A1	-0.019188
EPHA4	-0.019125
YAP1	-0.019120
CYB5B	-0.019012
VDR	-0.019005
C17orf96	-0.018908
DBF4	-0.018906
MAP3K1	-0.018876
FAM171B	-0.018869
SWI5	-0.018858
FAM60A	-0.018844
SEH1L	-0.018841
EBNA1BP2	-0.018784
PDGFA	-0.018764
LOC285074	-0.018675
THAP10	-0.018640
GLCE	-0.018632
NDC80	-0.018580
ZNF706	-0.018536
COA6	-0.018464
OXR1	-0.018397
CHCHD4	-0.018378
PIGW	-0.018378
TSPAN5	-0.018363
CTNNAL1	-0.018361
ACTL6A	-0.018269
RBL2	-0.018210
LINC00623	-0.018183
APOBEC3G	-0.018093
THAP1	-0.018066
LYRM1	-0.017977
TXNIP	-0.017914
PABPC3	-0.017888
SUMO2	-0.017886
PTPN12	-0.017882
MOAP1	-0.017880
MRPS6	-0.017819
SIMC1	-0.017810