!direction	-1
!num_genes	147
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	MLN4924
!smiles	C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=O)N
!pubchem_cid	73014187
!cell_type	A375 melanoma cell line - 1 Hour
!organism	human
!end_metadata
UBC	-0.236939
ND6	-0.210536
MRPL33	-0.111926
RPS2	-0.107580
ATP6	-0.092411
ATP6V0B	-0.076428
MT1HL1	-0.061169
SNRPF	-0.060402
LSM7	-0.052855
RPS13	-0.051721
DYNLL1	-0.050587
RPL41	-0.050102
RPS20	-0.048836
COX1	-0.048567
LASP1	-0.047732
RPL18	-0.046006
DKK1	-0.045980
RPS18	-0.044465
EEF1B2	-0.042229
SLIRP	-0.042222
RPS26	-0.041684
RPS10	-0.040300
GGCT	-0.040195
MTHFD1	-0.040029
PSMA4	-0.039650
ID3	-0.039395
RPL28	-0.038639
EIF2A	-0.038492
TUBA1B	-0.037808
ARPC3	-0.036786
CDC20	-0.036745
PCID2	-0.036577
RPL7	-0.036129
S100A2	-0.035886
USP11	-0.035763
COX2	-0.035709
UBB	-0.035365
KARS	-0.035319
ATP6V0C	-0.035246
RPL24	-0.035080
RPS27	-0.034651
UFD1L	-0.034575
UBA52	-0.034424
RPL26L1	-0.033372
S100A10	-0.032915
PABPC3	-0.032522
RPL12	-0.032438
SYAP1	-0.032344
FAM35A	-0.032255
TMEM147	-0.031757
PDCD10	-0.031324
RPS6	-0.031205
CCDC12	-0.030981
SLC12A7	-0.030642
RPL32	-0.030581
ILK	-0.030073
MAD2L2	-0.030039
HSP90AB1	-0.029766
CHCHD1	-0.029723
OVOS2	-0.029248
DDB1	-0.029104
MED10	-0.028971
RPL21	-0.028316
RPL6	-0.028093
RPL11	-0.027733
HMGB2	-0.027721
ACTG1	-0.027473
RPL36AL	-0.027371
UBA2	-0.027278
LAP3	-0.027255
SPDL1	-0.027086
ITPA	-0.026756
PTS	-0.026378
MRPL24	-0.026180
PSMA2	-0.026065
TUBA1C	-0.025885
COX14	-0.025861
ICT1	-0.025628
PRMT1	-0.025545
EIF3L	-0.025529
PDHX	-0.024779
ZCRB1	-0.024602
SNRPA1	-0.024508
FAM136A	-0.024278
RPS15A	-0.024144
KPNA2	-0.024104
HSBP1	-0.023770
RPLP1	-0.023736
POLR3K	-0.023590
NACA	-0.023513
UQCRH	-0.023361
SMC2	-0.023147
PEBP1	-0.023122
LYPLA2	-0.023044
NAT10	-0.022888
RPL5	-0.022633
ERLIN1	-0.022491
CFL1	-0.022402
MANSC1	-0.022288
PPA1	-0.022231
MAGEA6	-0.022171
SHFM1	-0.022100
H2AFZ	-0.022007
GANAB	-0.021228
COX3	-0.021054
CLIC4	-0.020718
PIH1D1	-0.020683
LAMTOR1	-0.020560
HADHB	-0.020432
PSMB6	-0.020215
SEC13	-0.020062
AAMP	-0.019976
SLC34A3	-0.019506
RAD21	-0.019371
PFN1	-0.019262
TPT1	-0.019216
CENPM	-0.019195
LAMTOR5	-0.019077
NOB1	-0.019050
ID1	-0.018886
UFC1	-0.018616
RPL29	-0.018569
TTC19	-0.018516
KIAA0894	-0.018490
MAGEA5	-0.018321
TMEM14B	-0.018207
USMG5	-0.018061
DDX3X	-0.018054
RPL10A	-0.018000
SPARC	-0.017980
SLC26A11	-0.017873
ATP5J	-0.017849
RILPL2	-0.017716
HIST1H4C	-0.017669
CPSF4	-0.017648
ATP5B	-0.017645
NDUFB10	-0.017519
MSN	-0.017498
OST4	-0.017239
RPL23AP32	-0.017220
UBE2Q2	-0.017189
RAN	-0.017031
CAMLG	-0.016991
RPSA	-0.016985
NSUN2	-0.016856
EPHA2	-0.016716
RPP25L	-0.016701