!direction	-1
!num_genes	243
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	17beta-estradiol
!ligand_id	CHEBI:16469
!cell_type	U2OS osteosarcoma cell line
!organism	human
!end_metadata
VIM	-0.175962
ANXA2	-0.168613
S100A2	-0.138373
MT2A	-0.135921
HSPA8	-0.135440
CYR61	-0.126640
HN1	-0.107962
TMSB10	-0.103890
HSPB1	-0.097039
CAPN2	-0.090163
KRT18	-0.083488
LDHA	-0.083334
HSPD1	-0.079693
HSP90AA1	-0.076514
HMGA1	-0.076173
ACTB	-0.074098
SFN	-0.073554
HSP90AB1	-0.072836
FKBP1A	-0.063655
GPR56	-0.062209
ENO1	-0.059495
SRI	-0.058983
IRAK1	-0.058149
EIF4A1	-0.055773
LDHB	-0.054200
INHBA	-0.050246
CORO1C	-0.048204
PKM	-0.046853
RPS17	-0.045887
RPL7	-0.045267
MT1X	-0.045198
ODC1	-0.043611
YWHAZ	-0.042725
LAMB3	-0.042123
ANXA1	-0.040286
TIMP1	-0.039585
TYMS	-0.039046
RANBP1	-0.038534
TGM2	-0.037791
TPM1	-0.037780
NME1	-0.037601
CALM2	-0.037419
NNMT	-0.037140
CA2	-0.036089
CCT3	-0.034782
FLNC	-0.034754
TUBB	-0.033676
RHOC	-0.033436
RPL24	-0.033426
UPP1	-0.033330
MXRA7	-0.033222
FHL2	-0.033156
RPL22	-0.032952
IMPDH2	-0.032853
ANXA5	-0.032536
AXL	-0.032344
GLRX	-0.031676
PCBP1	-0.031610
FBN2	-0.031430
CALB2	-0.031251
CTGF	-0.030686
HIF1A	-0.030551
HNRNPA1	-0.030396
CAPNS1	-0.030314
EXT1	-0.030214
CSRP1	-0.029856
NPM1	-0.029776
RPS21	-0.029118
RPL5	-0.029067
SNAPC1	-0.028812
RTN4	-0.028725
H2AFZ	-0.028680
MT1H	-0.028670
RPS12	-0.028322
NCOR2	-0.027936
GADD45A	-0.027564
EIF3E	-0.027428
CLIC1	-0.027355
SOD1	-0.027004
PPA1	-0.026941
SERPINE1	-0.026908
DUSP1	-0.026814
CAP1	-0.026763
CCT2	-0.026622
ID1	-0.026328
KRT81	-0.026322
PDHB	-0.026212
ZFP36L1	-0.026170
TPI1	-0.025633
HSPH1	-0.025610
PEA15	-0.025529
CAPRIN1	-0.025482
DDX21	-0.025458
APEX1	-0.025379
KRT17	-0.024784
TJP1	-0.024539
CCT4	-0.023957
SFPQ	-0.023421
DDAH1	-0.023400
SARAF	-0.023210
GNAI3	-0.023189
PDGFC	-0.022639
SOX4	-0.022437
RAN	-0.022365
PSMD2	-0.022343
HMGB1	-0.022341
KRT8	-0.022297
ALCAM	-0.022222
GDI2	-0.021892
RPL13A	-0.021492
PPP4R1	-0.021467
SLC38A2	-0.021000
RAB31	-0.020917
HNRNPAB	-0.020713
PODXL	-0.020610
RND3	-0.020444
CKS2	-0.020414
GNB2L1	-0.020332
FABP5	-0.020304
VDAC3	-0.020277
DSTN	-0.019869
ID3	-0.019862
PSMG2	-0.019647
RPL19	-0.019576
FHL1	-0.019334
ATIC	-0.019255
S100A11	-0.019244
RALB	-0.019023
TUBB4B	-0.018938
KLK6	-0.018810
NONO	-0.018742
GPRC5A	-0.018595
PAICS	-0.018568
CDK4	-0.018520
SRSF2	-0.018430
ADSL	-0.018359
TXNRD1	-0.018318
DKC1	-0.018234
LBR	-0.018213
BCL2L1	-0.018185
NHP2L1	-0.018183
MYH9	-0.018056
CCT8	-0.018045
MYC	-0.017886
ABCE1	-0.017833
CBX1	-0.017612
VDAC1	-0.017528
ZYX	-0.017527
CTPS1	-0.017513
NDN	-0.017450
HNRNPA2B1	-0.017413
ATP5B	-0.017320
CCT6A	-0.017307
RPS24	-0.017306
EIF4G2	-0.017236
CLTC	-0.017197
SHFM1	-0.017195
DFNA5	-0.017042
MGST3	-0.017011
GJA1	-0.016997
SUCLG1	-0.016973
KLF10	-0.016789
PGK1	-0.016785
RPS15A	-0.016762
BHLHE40	-0.016723
IL7R	-0.016698
NACA	-0.016586
USP14	-0.016380
DLC1	-0.016331
PCNA	-0.016303
COL4A1	-0.016215
SOX9	-0.016108
KTN1	-0.016108
NOP56	-0.016102
SMS	-0.016037
PON2	-0.016000
NCL	-0.015935
ANXA10	-0.015922
GALNT2	-0.015888
PTGES3	-0.015807
LIMS1	-0.015794
SRM	-0.015757
MTHFD1	-0.015751
HNRNPM	-0.015705
PRMT1	-0.015704
BANF1	-0.015704
IPO7	-0.015581
ITGA3	-0.015570
IER2	-0.015494
S100A6	-0.015478
TARDBP	-0.015472
KARS	-0.015240
SFRP1	-0.015171
RPL37A	-0.015132
CDC20	-0.014955
HSPE1	-0.014893
ATP1A1	-0.014881
H2AFY	-0.014876
RPL36A	-0.014761
ANP32A	-0.014712
ARL6IP5	-0.014684
YBX3	-0.014671
RAC1	-0.014574
RNPS1	-0.014567
RPS13	-0.014498
CNN3	-0.014442
MRPL3	-0.014438
PHB	-0.014386
PTOV1	-0.014330
TAF6	-0.014284
TNPO1	-0.014284
LTA4H	-0.014275
SEMA3B	-0.014268
PRDX4	-0.014259
KHDRBS1	-0.014247
ATXN10	-0.014223
EEF1D	-0.014182
MBOAT7	-0.014161
WNT5A	-0.014153
SEPT7	-0.014110
EIF4B	-0.014075
CTNNAL1	-0.013850
PRNP	-0.013799
MTCH2	-0.013750
FUT8	-0.013686
SH3BGRL3	-0.013652
YWHAH	-0.013633
DYNLL1	-0.013615
TSTA3	-0.013562
MCM2	-0.013515
SELT	-0.013508
MTCH1	-0.013462
RPL12	-0.013385
SQLE	-0.013380
FLNA	-0.013312
CD151	-0.013282
EDN1	-0.013247
POLR2B	-0.013148
CYCS	-0.013115
WBSCR22	-0.013100
HIST1H2AC	-0.013091
XRCC6	-0.013077
CSTB	-0.013064