!direction	-1
!num_genes	335
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Heroin
!smiles	CC(=O)OC1C=CC2C3CC4=C5C2(C1OC5=C(C=C4)OC(=O)C)CCN3C
!drugbank_id	DB01452
!pubchem_cid	5462328
!cell_type	striatum, day 3 treatment
!organism	mouse
!end_metadata
ND4L	-0.122372
GLUL	-0.108019
C2orf40	-0.106211
STMN1	-0.090096
MXI1	-0.086448
SOSTDC1	-0.085821
WFDC2	-0.082932
SLC13A4	-0.074614
PMCH	-0.073197
MAP2K1	-0.072199
IL22RA1	-0.072133
CTSS	-0.070130
SLC17A6	-0.069922
SLC12A5	-0.069037
IDO1	-0.066528
TTR	-0.065549
NDUFB4	-0.064344
NDRG4	-0.063344
TNNT1	-0.062519
RASGEF1A	-0.062094
KPNA3	-0.059608
SLC6A13	-0.059280
IGF2	-0.057770
SLC6A12	-0.056686
KIAA1462	-0.055561
VAPA	-0.055075
ENPP2	-0.054087
PIN4	-0.053965
INTS8	-0.052361
IGFBP2	-0.051530
NDUFA5	-0.050814
SDHD	-0.050197
USMG5	-0.050076
CD34	-0.049958
CDC123	-0.049285
TIMP1	-0.049223
CRYBG3	-0.049155
CHMP5	-0.048485
NRN1	-0.047806
H3F3C	-0.047310
GOPC	-0.046653
KCNE2	-0.046225
ACTA2	-0.045967
OXT	-0.045956
FOLR1	-0.045777
HLA-DQA1	-0.045704
IMPA1	-0.045577
C1QL2	-0.045371
DDX3X	-0.045301
CLDN2	-0.045198
S100B	-0.045050
PTPRA	-0.044503
GRAMD4	-0.044087
TRRAP	-0.043974
TJP1	-0.043905
CD74	-0.043645
GBX2	-0.043136
OPALIN	-0.043041
R3HDM2	-0.042760
TRIM59	-0.042600
COX2	-0.042548
SFR1	-0.042262
SEC11C	-0.041400
CLDN5	-0.041247
HCRT	-0.040897
ARHGAP33	-0.040672
GPR88	-0.039971
MICU3	-0.039738
YWHAE	-0.038924
KL	-0.038451
NLGN1	-0.038168
SPARCL1	-0.038025
HSP90AA1	-0.037941
ST13	-0.036892
VHL	-0.036816
AVP	-0.036606
DIO2	-0.036401
COL8A1	-0.035869
CACYBP	-0.035635
VPS26B	-0.035363
TXNRD1	-0.035328
SOX18	-0.035186
BGN	-0.035090
OSBPL11	-0.035071
CYFIP2	-0.034944
THBD	-0.034808
HSPA5	-0.034659
RNF115	-0.034610
TUBA1A	-0.034536
GRP	-0.033415
SARNP	-0.033326
WNT2	-0.033269
NECAB1	-0.033148
NDUFB5	-0.033131
OTUD6B	-0.032830
NR4A2	-0.032782
ZBTB8OS	-0.032517
PLS3	-0.032379
SERPING1	-0.032252
TOMM70A	-0.032158
SLC7A6OS	-0.032077
GNB2L1	-0.031637
PLA2G7	-0.031595
EFNB2	-0.030846
GPM6B	-0.030756
SELK	-0.030729
IDI1	-0.030413
CD93	-0.030332
PSMD14	-0.030315
OTX2	-0.030300
CPNE9	-0.029979
PCDHB11	-0.029978
NPC2	-0.029972
ALCAM	-0.029934
B4GALT2	-0.029887
PGRMC1	-0.029868
PCDHB16	-0.029811
SLC35D3	-0.029378
MYL4	-0.029154
KPNB1	-0.029107
CETN2	-0.029035
TMEM184C	-0.028909
ISG15	-0.028782
ST6GALNAC2	-0.028747
SLC16A8	-0.028592
JAM3	-0.028574
TPPP	-0.028549
PENK	-0.028499
APCDD1	-0.028301
SLC3A2	-0.028252
DZANK1	-0.027861
DCN	-0.027853
KIAA0196	-0.027834
C16orf80	-0.027682
AEBP1	-0.027372
MSX1	-0.027347
RBM14	-0.027326
ATP5A1	-0.027259
PAIP2	-0.027216
HLA-DQB1	-0.027098
CYP26B1	-0.027089
EIF4G2	-0.026846
TBX1	-0.026815
CA4	-0.026785
HOXC4	-0.026716
PTRF	-0.026489
RER1	-0.026406
PDCD5	-0.026195
SPTSSA	-0.025835
EMP2	-0.025620
TEX2	-0.025618
KCNA4	-0.025452
PCNA	-0.025258
KLF2	-0.025184
IGFN1	-0.025135
MYL9	-0.025075
SNX3	-0.025061
CAMP	-0.024910
EMP1	-0.024760
EIF4B	-0.024682
BCAS2	-0.024643
SLC39A10	-0.024637
TBC1D8	-0.024546
PTPRB	-0.024477
ADRBK1	-0.024471
GHITM	-0.024362
SPON2	-0.024257
TMED2	-0.024250
CRYAB	-0.024217
MYH14	-0.024165
ZNF777	-0.024053
MGP	-0.024040
GJB2	-0.023998
LMBR1	-0.023970
CD72	-0.023810
LPAR1	-0.023706
HSD17B14	-0.023497
SH3RF2	-0.023374
SOX2	-0.023205
OGN	-0.023126
FBLIM1	-0.023073
CRYM	-0.023018
OLAH	-0.022929
ZNF710	-0.022898
PHF12	-0.022891
RASSF3	-0.022827
ZBED3	-0.022792
KLHL13	-0.022721
VPS4B	-0.022685
NOL7	-0.022624
RNPC3	-0.022581
STX1A	-0.022483
ZNF442	-0.022391
S100A10	-0.022380
NTNG1	-0.022373
SLC23A2	-0.022309
PIGT	-0.022276
GLTSCR2	-0.022183
TREML2	-0.022099
RGS5	-0.022069
PTCHD1	-0.021920
GBP4	-0.021879
EAPP	-0.021799
RNF112	-0.021677
EMC7	-0.021645
UBE2N	-0.021562
RGS16	-0.021458
IFITM3	-0.021426
PPP1R14A	-0.021399
RASGRP2	-0.021397
TSC1	-0.021380
GTF2B	-0.021235
FH	-0.021161
TBC1D19	-0.021153
LGALS3BP	-0.021090
BAG5	-0.021047
ID3	-0.020887
NDUFB9	-0.020874
OR4C3	-0.020827
HECTD1	-0.020778
FAM131A	-0.020729
COX20	-0.020686
VAT1	-0.020640
TTL	-0.020560
RWDD4	-0.020539
TMEM203	-0.020496
C12orf65	-0.020484
MRPL13	-0.020370
NAP1L5	-0.020190
ACADSB	-0.020112
NDN	-0.020070
RXRG	-0.019988
SHB	-0.019980
AKR1E2	-0.019948
TEX38	-0.019911
BEGAIN	-0.019900
S100A13	-0.019872
LMO2	-0.019864
OMD	-0.019840
LRRC4C	-0.019733
SUCLA2	-0.019640
TXNDC12	-0.019627
LAPTM4B	-0.019623
INPP5J	-0.019590
SLC38A4	-0.019581
ABCD3	-0.019544
KCTD12	-0.019528
NDUFAF5	-0.019498
IGSF1	-0.019455
DRD2	-0.019403
HSPG2	-0.019396
MCCC1	-0.019336
EVL	-0.019228
CAV1	-0.019114
CPEB2	-0.019080
F5	-0.019032
TM4SF20	-0.019015
RSPO2	-0.019015
CLTA	-0.019014
NKIRAS1	-0.018950
LHX8	-0.018912
ARPC2	-0.018843
RPE65	-0.018840
CABP7	-0.018721
PSTK	-0.018689
LAG3	-0.018653
MEIS2	-0.018628
GSTM1	-0.018540
SOX17	-0.018534
GSX2	-0.018428
EIF4E	-0.018427
KATNAL1	-0.018423
C11orf54	-0.018414
EIF3C	-0.018371
NKX2-1	-0.018360
RSU1	-0.018344
STEAP4	-0.018310
DDX50	-0.018309
FOXC1	-0.018234
LPGAT1	-0.018212
ZNF687	-0.017966
STK32B	-0.017944
CRYZL1	-0.017944
MYH11	-0.017936
RCN1	-0.017904
ST8SIA3	-0.017843
SLC25A35	-0.017843
NTRK3	-0.017804
TGFA	-0.017757
IRGC	-0.017575
CHP2	-0.017541
ITIH3	-0.017480
ARL5B	-0.017478
RGMA	-0.017457
PLTP	-0.017414
IST1	-0.017398
YWHAG	-0.017294
SRP72	-0.017211
ACTG2	-0.017211
TMEM251	-0.017190
MAVS	-0.017133
NDUFB10	-0.017127
NR1D2	-0.017121
MMP2	-0.017116
FOXQ1	-0.017066
SEMA4C	-0.017036
MEDAG	-0.017027
ATP6V1A	-0.016978
UACA	-0.016919
MIS12	-0.016908
PDAP1	-0.016804
NDUFB2	-0.016786
RINL	-0.016752
PRSS35	-0.016671
USP14	-0.016571
TPBGL	-0.016481
CALML4	-0.016447
FXR2	-0.016441
MRPL52	-0.016431
DYNLT3	-0.016420
MAP1LC3B	-0.016398
B4GALT4	-0.016389
S100A6	-0.016381
GNL2	-0.016313
PTPRT	-0.016301
ADAM9	-0.016301
ABCG5	-0.016296
EDN1	-0.016272
ABHD3	-0.016209
STEAP1	-0.016194
BANK1	-0.016180
SLCO1C1	-0.016156
SLC39A1	-0.016100
SMARCA5	-0.016075
ZDHHC5	-0.016056