!direction	-1
!num_genes	260
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	17beta-estradiol
!ligand_id	CHEBI:16469
!cell_type	U2OS osteosarcoma cell line
!organism	human
!end_metadata
S100A10	-0.204791
VIM	-0.191389
TPM1	-0.171614
MT2A	-0.157785
LAPTM4B	-0.149912
SRI	-0.148339
TMSB10	-0.147118
GJA1	-0.128624
EEF1A2	-0.120864
DBI	-0.105345
NNMT	-0.103197
GPRC5A	-0.099536
KRT18	-0.096608
KRT81	-0.093104
MT1H	-0.081891
MT1X	-0.065331
SOD1	-0.063812
ANXA2	-0.063191
MAGED1	-0.062506
S100A2	-0.061207
RPL23	-0.061087
SFN	-0.058406
ID1	-0.058099
CLU	-0.058005
MFAP2	-0.056085
SLC38A2	-0.055295
CYR61	-0.052323
CAPNS1	-0.050342
RPL12	-0.049521
PRMT1	-0.047392
ANXA10	-0.046924
IMPDH2	-0.046885
KRT17	-0.046856
RPL18	-0.046480
LDHB	-0.045662
RPL19	-0.045482
RPS25	-0.045192
ARL4C	-0.044865
LDHA	-0.044291
BMP4	-0.043920
ATP5B	-0.043143
TPI1	-0.042202
GPX4	-0.042195
EEF1D	-0.042073
NPM1	-0.042022
ENC1	-0.041833
RPL13A	-0.041317
TPT1	-0.041205
YBX3	-0.041185
RPS14	-0.040865
RPS12	-0.040615
FHL1	-0.040115
LOXL1	-0.039366
SHC1	-0.039194
TUBB	-0.038967
SNRPD2	-0.038581
RPL17	-0.038548
RPS11	-0.038056
CLDND1	-0.038028
RPS26	-0.037834
APEX1	-0.037811
RPL35	-0.037684
FKBP1A	-0.037279
PGK1	-0.036930
SOX4	-0.036591
RPL10A	-0.036070
ALPP	-0.035896
TUBB3	-0.035574
BMP5	-0.035529
FBN2	-0.035506
EIF2AK1	-0.035457
RPL28	-0.034612
SERF2	-0.034351
VAPA	-0.034152
UCP2	-0.033824
EIF4A1	-0.033542
RPL34	-0.033341
PODXL	-0.033269
RPL36A	-0.032900
RPS7	-0.032146
MYL12B	-0.031597
TRIM28	-0.031584
DYSF	-0.031030
LAMP1	-0.030833
MN1	-0.030766
BANF1	-0.030478
COL4A1	-0.029983
RPL32	-0.029819
FSCN1	-0.029746
SERPINE1	-0.029603
RPS15A	-0.028815
HMGN2	-0.028369
CD63	-0.028350
EIF4B	-0.028334
RPS18	-0.027771
SH3BP4	-0.027602
FTH1	-0.027501
SARAF	-0.027073
RPS27	-0.026929
RANBP1	-0.026874
TMEM258	-0.026775
PHB2	-0.026659
NGFRAP1	-0.026434
THY1	-0.026299
ABLIM1	-0.026123
YWHAZ	-0.025851
SLC25A5	-0.025635
ANXA5	-0.025627
RAB13	-0.025607
NIPSNAP1	-0.025576
RPS27L	-0.025462
RPS6	-0.025329
PPM1D	-0.025300
CNN3	-0.024976
IER3	-0.024948
HSPD1	-0.024718
HIST1H2BK	-0.024698
EMP3	-0.024286
LASP1	-0.024218
RAB31	-0.024082
COL1A1	-0.023997
RPL7A	-0.023972
TGM2	-0.023639
TNFRSF1A	-0.023549
KLK6	-0.023527
SNAI2	-0.023522
S100A6	-0.023384
LOXL2	-0.023307
RPS8	-0.023212
TGIF1	-0.023085
TRAM1	-0.023007
CCT4	-0.022978
GNB2L1	-0.022829
RPL6	-0.022420
NDUFB4	-0.022229
PRAME	-0.022135
SLC12A7	-0.022118
VAT1	-0.022014
CHD4	-0.021985
MXRA7	-0.021582
RCN1	-0.021538
RPL9	-0.021358
CSDE1	-0.021306
KRT8	-0.021075
SSR2	-0.020931
HIF1A	-0.020870
H3F3B	-0.020670
IFNGR2	-0.020355
NCL	-0.020172
TPM2	-0.020070
DBN1	-0.019854
CCNG1	-0.019708
NME4	-0.019617
PABPC4	-0.019594
H1FX	-0.019401
SERPINH1	-0.019325
CTDSP2	-0.019272
HNRNPC	-0.019271
RPS23	-0.019261
TUBB4B	-0.019247
CNBP	-0.019171
SLC6A8	-0.019108
LGALS3	-0.019101
UQCR10	-0.019088
RPS29	-0.018796
ATP5J2	-0.018747
STAT3	-0.018622
MSN	-0.018503
PSME1	-0.018493
ANP32A	-0.018480
TSPO	-0.018360
HIST1H2AC	-0.018334
SLC18A3	-0.017933
CTSA	-0.017892
GNAI1	-0.017844
SFRP1	-0.017792
ATP5O	-0.017761
KHDRBS1	-0.017737
MXI1	-0.017700
SNRPD3	-0.017582
PDGFC	-0.017567
UQCRQ	-0.017512
PEBP1	-0.017470
GPX1	-0.017459
GLRX	-0.017458
RAP2B	-0.017406
RPL15	-0.017342
DFNA5	-0.017340
TRAM2	-0.017213
TNNT1	-0.017161
COTL1	-0.017147
USP22	-0.016979
CARHSP1	-0.016967
TNS3	-0.016933
TPST2	-0.016885
H2BFS	-0.016878
LAPTM4A	-0.016729
RPS9	-0.016690
MAGED2	-0.016681
SUMO3	-0.016562
COL5A1	-0.016529
CNIH1	-0.016460
MKNK2	-0.016359
HADHB	-0.016290
WNT5A	-0.016284
LTBP2	-0.016227
YBX1	-0.016179
TIMM8B	-0.016071
GNG5	-0.016029
NME1	-0.016016
CALM3	-0.015986
COX5B	-0.015973
RPL24	-0.015791
PAFAH1B3	-0.015689
CDK2AP1	-0.015686
CCNI	-0.015655
ATP5I	-0.015645
PSMG2	-0.015643
PTP4A1	-0.015607
HMGN1	-0.015560
AKAP12	-0.015402
STAU1	-0.015369
LGALS1	-0.015360
TUFT1	-0.015348
POLR2E	-0.015346
NONO	-0.015322
CTBP1	-0.015313
CERS2	-0.015312
RPL8	-0.015225
PAICS	-0.015200
HIST1H2BD	-0.015191
EDIL3	-0.015143
TMSB15A	-0.015121
INHBA	-0.015078
BSG	-0.014967
DRAP1	-0.014927
PPT1	-0.014914
SPARC	-0.014889
H1F0	-0.014639
HBP1	-0.014615
TBL1X	-0.014566
TLR4	-0.014545
RPLP2	-0.014528
EPHB4	-0.014474
CRYAB	-0.014367
SRP14	-0.014311
TXNIP	-0.014257
S100A11	-0.014223
PDXK	-0.014164
BTF3	-0.014091
TIMP1	-0.014047
NDN	-0.014039
ETHE1	-0.013956
EIF4A2	-0.013951
RAC1	-0.013923
ECHS1	-0.013831
MTHFD1	-0.013725
CPSF1	-0.013674
HMGB3	-0.013636
FOXN3	-0.013603