!direction	-1
!num_genes	283
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!gene	SIRT1
!cell	Liver
!perturbation	SIRT1 activator, SRT2104
!disease	Standard diet - 1.33 g drug per kg of chow
!end_metadata
LCN2	-0.098197
BHMT	-0.087478
SOCS3	-0.068613
CLPX	-0.065956
CHAC1	-0.062914
LRFN3	-0.057401
S100A8	-0.057021
ARNTL	-0.055203
S100A9	-0.054592
GADD45A	-0.053517
CXCL2	-0.053180
HSPB1	-0.052432
RSAD2	-0.049304
GJA4	-0.049013
NFIL3	-0.048131
FOXQ1	-0.047843
GADD45G	-0.047169
SAA1	-0.046487
BCL3	-0.045533
PLIN4	-0.045467
TJP3	-0.044389
ELOVL3	-0.043174
ETNPPL	-0.042903
AQP4	-0.042762
CDKN1A	-0.042339
INSIG2	-0.041494
LNX2	-0.041316
CRELD2	-0.040376
PLIN5	-0.039850
INSC	-0.038920
FAM107B	-0.038506
MREG	-0.037920
ATF3	-0.037652
RCAN1	-0.037492
RELL1	-0.037174
SRRM4	-0.036881
DUSP8	-0.036380
ISG15	-0.036304
CFD	-0.036160
GSTA5	-0.036033
AVPR1A	-0.035337
HCAR2	-0.035097
LGALSL	-0.035039
NANS	-0.034896
PID1	-0.034650
DCAF11	-0.034650
LENG9	-0.034505
CTSV	-0.034469
GCLC	-0.034324
LRTM1	-0.034068
HSPA5	-0.033982
SLC2A1	-0.033135
EIF1AX	-0.033105
GLDC	-0.032803
APOA4	-0.032588
GMPPB	-0.032559
DDX28	-0.032287
PLXNA2	-0.032272
SLC16A6	-0.031441
JUND	-0.031311
TMEM102	-0.031189
DEXI	-0.030888
DDC	-0.030878
DDIT4	-0.030741
CA14	-0.030672
SLC30A1	-0.030575
SYVN1	-0.030507
CYP2U1	-0.030465
RHOB	-0.030339
BCKDHB	-0.030059
PRMT6	-0.029972
GADD45B	-0.029922
IGFBP1	-0.029825
ST5	-0.029712
PGPEP1	-0.029474
THBD	-0.029133
LBP	-0.028853
LGALS1	-0.028352
SLC30A10	-0.028296
SEPT9	-0.028092
USP18	-0.027988
VPS37B	-0.027874
TREH	-0.027866
C8orf4	-0.027829
SGK1	-0.027563
ARHGEF19	-0.027536
PDK4	-0.027511
DHX58	-0.027463
LIPA	-0.027287
KDM6B	-0.026934
MPP6	-0.026839
SH3BP2	-0.026838
MEGF9	-0.026814
SNX24	-0.026714
IMPACT	-0.026599
ID3	-0.026457
PPP1R3B	-0.026324
S100A10	-0.026269
HOXA5	-0.026145
ZBTB22	-0.025965
TDO2	-0.025711
CMPK2	-0.025619
DMBT1	-0.025612
HDHD3	-0.025497
PLXNA1	-0.025422
HILPDA	-0.025359
ALG12	-0.025318
TJP2	-0.025009
AHCTF1	-0.024991
LASP1	-0.024912
LRG1	-0.024778
HIST1H3B	-0.024725
CCNG2	-0.024686
MED24	-0.024661
COX18	-0.024508
PPP1R3C	-0.024350
KLF2	-0.024330
FAM134B	-0.024310
HIST1H4J	-0.024171
NDRG1	-0.024124
KRAS	-0.024105
CHKA	-0.024085
DNAJB1	-0.024037
SEC24D	-0.023966
WFDC2	-0.023864
ETS2	-0.023856
TP53INP1	-0.023685
TMEM125	-0.023444
SMAP1	-0.023443
TUBB4B	-0.023442
CD93	-0.023415
MTNR1A	-0.023398
ZFHX2	-0.023390
PTEN	-0.023282
FBF1	-0.023219
ATXN10	-0.023194
CRYL1	-0.023115
AASS	-0.023057
C11orf54	-0.023021
OSBPL11	-0.022928
RTN4RL1	-0.022905
TMEM167B	-0.022835
BLOC1S4	-0.022767
COG8	-0.022718
SLC16A10	-0.022703
GNA11	-0.022661
SPON2	-0.022595
NGFR	-0.022563
LSM7	-0.022446
GNG5	-0.022381
KLF9	-0.022377
STAB2	-0.022366
SAA2-SAA4	-0.022339
SLC45A3	-0.022336
SRP9	-0.022191
SLC35B1	-0.022186
MRPS15	-0.022182
PALLD	-0.022172
RALB	-0.022128
OSGIN1	-0.021988
EFNB1	-0.021900
PNO1	-0.021882
HDC	-0.021874
MAP3K6	-0.021817
CRTC2	-0.021778
CRYGN	-0.021707
FPGS	-0.021641
FBXO31	-0.021625
PLIN2	-0.021620
PTPRB	-0.021600
BOLA3	-0.021581
NAGS	-0.021545
C19orf80	-0.021528
TUBB6	-0.021523
LHFPL2	-0.021457
MIDN	-0.021383
TSR3	-0.021266
SDS	-0.021254
SLC15A3	-0.021225
ELAVL1	-0.021205
INO80B	-0.021201
SLC17A8	-0.021197
BTG1	-0.021196
LTV1	-0.021159
DDX50	-0.021143
ARL4A	-0.021135
OSBPL8	-0.021109
C1QBP	-0.021054
SPSB4	-0.020959
AMY2A	-0.020930
FAIM	-0.020857
MRPS35	-0.020851
METTL9	-0.020729
PJA2	-0.020654
ACBD3	-0.020640
NAT8	-0.020605
QRSL1	-0.020577
FAM195A	-0.020513
SEMA4B	-0.020489
OBP2B	-0.020483
STAT3	-0.020479
HELZ2	-0.020471
ATP1B1	-0.020416
MRAP	-0.020376
DDX52	-0.020375
DPM2	-0.020373
TEK	-0.020365
FNDC3B	-0.020354
DLD	-0.020297
HAPLN3	-0.020288
DAPK3	-0.020257
STARD13	-0.020246
SLC30A6	-0.020189
HIST1H4F	-0.020182
HR	-0.020162
CCDC90B	-0.020043
SELK	-0.020040
TPST2	-0.020013
FEN1	-0.020010
NR2C2AP	-0.019995
USP33	-0.019985
DCUN1D4	-0.019936
CCDC151	-0.019932
SLC10A3	-0.019921
ENPP6	-0.019912
DERL3	-0.019881
DCTN6	-0.019814
LLGL2	-0.019786
KIAA1456	-0.019765
H2AFX	-0.019765
ACAT1	-0.019751
C3orf38	-0.019750
PPARGC1A	-0.019729
SGPL1	-0.019724
SECISBP2	-0.019723
SATB1	-0.019689
PLS3	-0.019603
EPT1	-0.019550
SNX8	-0.019522
SQRDL	-0.019512
ADH4	-0.019506
ADPRH	-0.019485
STX18	-0.019478
WDR53	-0.019474
WNT2	-0.019446
SOWAHB	-0.019443
GFM2	-0.019431
FAIM3	-0.019428
ABCD1	-0.019427
TK2	-0.019420
C9orf142	-0.019399
UBAC2	-0.019365
FAM219B	-0.019321
NUPL2	-0.019288
LRP11	-0.019221
GHITM	-0.019217
ITPK1	-0.019180
STX5	-0.019153
CLDN1	-0.019144
TTPA	-0.019109
ZFPL1	-0.019107
ODF3B	-0.019066
TMIE	-0.019036
TMED3	-0.018986
CYP4F8	-0.018958
TMED2	-0.018937
KRT18	-0.018934
PLIN3	-0.018895
CDK2AP2	-0.018865
RNF186	-0.018809
ACP2	-0.018733
LMO4	-0.018732
GBF1	-0.018731
RAD54L2	-0.018703
SDHAF1	-0.018679
SEC61B	-0.018657
RAB32	-0.018641
SDSL	-0.018624
UQCC2	-0.018590
MAP1LC3B	-0.018579
HPDL	-0.018573
ST3GAL1	-0.018561
BLOC1S3	-0.018550