!direction	-1
!num_genes	370
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!drug_name	orotic acid
!smiles	C1=C(NC(=O)NC1=O)C(=O)O
!pubchem_cid	967
!cell_type	Livers ( from inbred Kyotos - fed a diet with 1% orotic acid) - 3 Day
!organism	rat
!end_metadata
PABPC4	-0.265529
CLU	-0.187755
KNG1	-0.178577
APOE	-0.173784
COMT	-0.155384
MPC1	-0.144635
GC	-0.141585
MGST1	-0.126494
ITIH3	-0.123596
PIGR	-0.120638
UBC	-0.112815
FABP1	-0.112611
PCBD1	-0.110482
APOH	-0.106660
ACAA2	-0.101974
AGT	-0.100935
RPS29	-0.098480
INSIG1	-0.097969
PON1	-0.097515
CYP1A2	-0.097171
ADH1C	-0.097132
SOD1	-0.095485
THRSP	-0.094273
MGST3	-0.093552
GPX1	-0.093122
BHMT	-0.092679
COX3	-0.091442
ATP6	-0.091290
AMBP	-0.089547
C9	-0.084398
F2	-0.082524
HPX	-0.080472
HPD	-0.080017
HSD11B1	-0.079811
GAMT	-0.079106
GSTM5	-0.078591
ARG1	-0.078369
F10	-0.075670
RPS12	-0.075187
ITIH4	-0.075163
PPIA	-0.073050
HRSP12	-0.072755
FBP1	-0.071678
ZFP36L1	-0.071148
SULT2A1	-0.070018
RPS21	-0.069507
PEMT	-0.067894
PAH	-0.065167
PCK1	-0.064421
AHCY	-0.063242
TAT	-0.062845
GSTA5	-0.062578
POMP	-0.062485
RPS16	-0.061258
SDC4	-0.061014
SULT1E1	-0.060138
CA3	-0.058747
EPHX1	-0.058426
APOM	-0.058112
ALDH2	-0.058018
HMGCS1	-0.057639
CTH	-0.057341
PCYT2	-0.057067
KHK	-0.056941
COX4I1	-0.055730
APOA1	-0.055255
BSG	-0.055038
HMGCS2	-0.054548
NDUFB2	-0.054269
ACADM	-0.054186
B2M	-0.053461
SORD	-0.053138
RPS13	-0.051735
CFB	-0.051706
TECR	-0.051621
AFM	-0.051611
ALDH1L1	-0.051250
TTR	-0.050904
COX8A	-0.050857
TPI1	-0.049375
ERRFI1	-0.049076
FTH1	-0.048531
CPS1	-0.048524
HAO2	-0.046357
RPS25	-0.045713
GNMT	-0.045562
RPL27	-0.045411
CYP2E1	-0.045348
RPL22	-0.044539
GSTM1	-0.043894
ATP5H	-0.043618
APOC4	-0.043279
ECHS1	-0.042514
NDUFB9	-0.041951
GHR	-0.041788
PAICS	-0.041157
COX2	-0.040862
SEPP1	-0.040553
HAAO	-0.039872
LDHA	-0.039539
SLC37A4	-0.039038
CDO1	-0.037620
FGG	-0.036722
DAO	-0.035906
SULT1B1	-0.035789
GJB1	-0.035674
GSTO1	-0.035392
CTSS	-0.035301
FAU	-0.034818
AKR1D1	-0.034806
CAT	-0.034615
ACTB	-0.033640
NDUFC1	-0.033559
APCS	-0.033487
OAZ1	-0.032482
SCD	-0.031934
KYNU	-0.031828
PGRMC1	-0.031792
HSPD1	-0.031744
MIF	-0.031689
PSAP	-0.031546
RBP4	-0.031515
UGT2B28	-0.031393
VTN	-0.031390
FMO1	-0.031386
HIBADH	-0.031303
SLC25A5	-0.031113
APOB	-0.030870
DBI	-0.030687
FAH	-0.030572
ASGR1	-0.030390
FTL	-0.029579
PHB2	-0.029535
DDT	-0.029527
GPX4	-0.029399
CSAD	-0.029312
PXMP2	-0.029300
TPT1	-0.029202
SPP2	-0.029096
COX6A1	-0.028802
CD81	-0.028488
COX7B	-0.028336
RPL27A	-0.027937
TDO2	-0.027007
LCAT	-0.026995
SLC22A1	-0.026768
PPP2R5A	-0.026473
UGT2B17	-0.026253
RPS27L	-0.026055
ND1	-0.025934
HSPE1	-0.025816
LAMP2	-0.025709
PPDPF	-0.025202
NDUFB4	-0.024623
MAOB	-0.024608
ACOX2	-0.024399
SLCO2A1	-0.024283
BAAT	-0.024191
PSMB2	-0.024136
NDUFA3	-0.024078
CTSH	-0.024056
NDUFA6	-0.024040
GLUL	-0.023927
SLC22A7	-0.023880
PGK1	-0.023796
TTC36	-0.023750
TMEM47	-0.023613
RPL37	-0.023558
MARC2	-0.023227
FABP6	-0.023194
TST	-0.023186
GOT2	-0.023157
ABCB11	-0.023093
ST6GAL1	-0.023058
CLEC4F	-0.022998
ACLY	-0.022756
HSP90AA1	-0.022719
MDH2	-0.022601
YBX1	-0.022484
CST3	-0.022480
GAPDH	-0.022409
CTDSP1	-0.022364
HSD17B13	-0.022312
LAMP1	-0.022132
MGST2	-0.021983
NEDD8	-0.021933
RPS8	-0.021604
ACSL1	-0.021549
ABCC6	-0.021515
AQP9	-0.021476
RPL28	-0.021310
CYB5A	-0.021215
ABAT	-0.021115
DIO1	-0.021084
SERPINA3	-0.020823
IDH1	-0.020769
CISH	-0.020620
IGFBP1	-0.020384
GLUD1	-0.020286
GRN	-0.020233
BDH1	-0.020141
QDPR	-0.019965
GAA	-0.019939
ALDH7A1	-0.019901
ACADL	-0.019528
PPIF	-0.019468
APOA4	-0.019162
ALDOB	-0.019079
CPQ	-0.018932
AVPR1A	-0.018714
OPLAH	-0.018563
FUCA1	-0.018422
RPL39	-0.018279
PTGR1	-0.018260
DUSP1	-0.018118
CD63	-0.018065
DHCR7	-0.017896
HSD17B10	-0.017769
ATP6V0C	-0.017694
SNRNP70	-0.017666
PROC	-0.017610
KMO	-0.017580
AK3	-0.017535
ADH5	-0.017520
PDK2	-0.017368
JUN	-0.017366
NDUFA4	-0.017364
ALAD	-0.017175
ACSL5	-0.017136
PSMB5	-0.017045
DCAF11	-0.016663
SERPING1	-0.016472
CTSB	-0.016445
PDYN	-0.016439
DECR1	-0.016162
RPS3	-0.016138
HSD17B4	-0.016118
IFITM3	-0.016082
SIGMAR1	-0.015822
GSTK1	-0.015701
PRDX1	-0.015589
COX7A2	-0.015393
RGN	-0.015363
CP	-0.015192
KLF9	-0.015184
CYC1	-0.015159
RPL30	-0.015144
RPL13A	-0.014893
NDUFV3	-0.014849
SLC6A13	-0.014688
MBL2	-0.014614
PSMB4	-0.014611
NDUFV2	-0.014552
AQP8	-0.014546
RAF1	-0.014501
PSME1	-0.014428
PEBP1	-0.014294
RPL18A	-0.014283
DNAJA1	-0.014263
MSMO1	-0.014230
GABARAPL2	-0.014120
PRODH2	-0.013987
NDUFB10	-0.013908
HSD3B7	-0.013713
CTSD	-0.013701
PRKCG	-0.013566
HAGH	-0.013454
CYP51A1	-0.013387
RPS14	-0.013380
CDC37	-0.013299
SERPINA10	-0.013272
HIGD2A	-0.013251
ACADS	-0.013204
ATRN	-0.013179
ABHD14B	-0.013171
ENPP3	-0.013170
EHHADH	-0.013102
GNE	-0.013030
TTPA	-0.013029
PARK7	-0.012979
SERPINA6	-0.012892
RPS7	-0.012862
RPL5	-0.012845
CYP27A1	-0.012797
TSC22D1	-0.012786
APMAP	-0.012723
RPL9	-0.012691
COPZ1	-0.012655
CITED2	-0.012524
GCKR	-0.012373
SDS	-0.012356
DHFR	-0.012321
GRB2	-0.012268
EGR1	-0.012245
ATP5F1	-0.012034
GNAS	-0.011999
HNRNPAB	-0.011961
NQO1	-0.011919
MAOA	-0.011795
ALB	-0.011726
CNBP	-0.011668
RPL23	-0.011646
PLIN2	-0.011404
RPS23	-0.011292
GSTM2	-0.011228
PSMD2	-0.011212
RPL12	-0.011211
BCKDHA	-0.011065
SLC25A10	-0.010996
NDUFB3	-0.010988
HSD17B12	-0.010904
FCGRT	-0.010889
OAT	-0.010749
CA5A	-0.010731
PYGL	-0.010524
SLC25A30	-0.010480
LEP	-0.010461
PPP1CA	-0.010440
TMEM53	-0.010409
SLC28A2	-0.010361
ACAT2	-0.010336
PLG	-0.010335
GCHFR	-0.010290
DPYS	-0.010251
CD82	-0.010173
HADHB	-0.010057
RABAC1	-0.009929
RPS6	-0.009873
RBP1	-0.009803
RXRG	-0.009791
NR1H3	-0.009772
DDC	-0.009721
PRDX6	-0.009704
SLC41A2	-0.009684
ENPP2	-0.009681
RPL19	-0.009641
FGB	-0.009533
RPL31	-0.009495
C1QB	-0.009439
GPT	-0.009292
HMGA1	-0.009167
PROS1	-0.009156
RPL26	-0.009146
PTP4A1	-0.009136
ARFGAP2	-0.009110
AES	-0.009098
FOXA2	-0.009053
AMACR	-0.009004
RPS9	-0.008968
MFGE8	-0.008941
HNRNPU	-0.008939
CD151	-0.008932
CFP	-0.008856
CNN3	-0.008822
ITGB1	-0.008749
ATP5A1	-0.008681
CSNK2B	-0.008651
ACAT1	-0.008612
SUOX	-0.008535
RBCK1	-0.008527
KCNH3	-0.008464
TRAP1	-0.008398
ASGR2	-0.008367
GRB14	-0.008263
NDUFAB1	-0.008163
HNRNPF	-0.008070
CHKA	-0.008068
PTP4A2	-0.008061
RPL10A	-0.008047
SPR	-0.008015