!direction	-1
!num_genes	251
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	17beta-estradiol
!ligand_id	CHEBI:16469
!cell_type	U2OS osteosarcoma cell line
!organism	human
!end_metadata
TPM1	-0.151612
VIM	-0.139842
RPS27A	-0.133789
S100A10	-0.121582
SRI	-0.104946
GJA1	-0.102040
RPL8	-0.101370
TMSB10	-0.101255
CYR61	-0.099926
ANXA2	-0.098256
GPRC5A	-0.097011
NNMT	-0.094847
RPL34	-0.091521
KRT18	-0.086649
HSPB1	-0.081624
LDHB	-0.079874
RPL36A	-0.077321
LDHA	-0.077032
SLC38A2	-0.067497
RPS3	-0.066531
ID1	-0.065483
DBI	-0.064748
SOD1	-0.064369
GPR56	-0.061217
HNRNPA1	-0.060472
FKBP1A	-0.057480
RPL5	-0.055427
ACTB	-0.055208
HIF1A	-0.051862
ANXA10	-0.051783
SFN	-0.050722
KRT81	-0.050033
CLU	-0.049339
ARL4C	-0.048738
S100A2	-0.048513
RPS12	-0.048453
HSP90AA1	-0.047750
CAPNS1	-0.047499
PKM	-0.047400
FTH1	-0.047013
HSPD1	-0.046809
BMP5	-0.046377
RAB31	-0.044820
EEF1D	-0.044434
FHL1	-0.043982
HSP90AB1	-0.043804
NDN	-0.043718
RPL12	-0.043252
PTOV1	-0.043044
ANXA1	-0.042593
HSPA8	-0.042547
NGFRAP1	-0.041812
IMPDH2	-0.041653
CALM3	-0.041616
INHBA	-0.041429
SOX4	-0.039468
DUSP1	-0.038890
RPS10	-0.038534
RPS15A	-0.038529
RPS21	-0.038464
CITED2	-0.037419
MXRA7	-0.037188
EEF1B2	-0.037027
TRIM28	-0.037014
RPL14	-0.036459
FBN2	-0.036243
TPI1	-0.035932
GSTP1	-0.035815
MAGED1	-0.035671
SNAI2	-0.035140
RPL7	-0.034920
RPL13	-0.034868
NPC2	-0.034758
CD63	-0.034229
SH3BP4	-0.033953
RPL37	-0.033763
AP2M1	-0.033178
KRT8	-0.033130
TPT1	-0.033053
SGK1	-0.032969
RPLP2	-0.032786
ENO1	-0.032346
MFAP2	-0.032248
PPA1	-0.031972
CCT3	-0.031946
MXI1	-0.031760
RPS26	-0.031033
NIPSNAP1	-0.030706
NCL	-0.030669
EIF2AK1	-0.030643
CDK4	-0.030537
FHL2	-0.030514
PRMT1	-0.030176
VAPA	-0.030139
CADM1	-0.030041
SPTAN1	-0.029954
MGST3	-0.029850
CORO1C	-0.029590
CALM2	-0.029500
KLK6	-0.029425
ALCAM	-0.029200
NME4	-0.029050
RPL4	-0.028936
RPL30	-0.028750
ENC1	-0.028124
LAPTM4A	-0.028044
FLNA	-0.027883
TAGLN2	-0.027772
CNN3	-0.027726
TUBB4B	-0.027689
RPS27	-0.027438
TUBB	-0.027310
APEX1	-0.027146
GNB2L1	-0.026967
NME1	-0.026899
LAMB3	-0.026736
RPL13A	-0.026717
RPL22	-0.026675
S100A6	-0.026420
CYP26B1	-0.026304
QARS	-0.026226
BANF1	-0.025988
VTI1B	-0.025885
NONO	-0.025768
UQCRQ	-0.025718
WNT5A	-0.025623
BMP4	-0.025555
YBX3	-0.025381
IRAK1	-0.024777
H1FX	-0.024684
MAGED2	-0.024396
SPARC	-0.024116
PDGFC	-0.024014
MYH9	-0.023846
FAU	-0.023620
MT1H	-0.023579
GPX4	-0.023475
CSE1L	-0.023453
RCN1	-0.023452
EIF3E	-0.022917
RANBP1	-0.022604
SFRP1	-0.022471
POLR2E	-0.022396
VAT1	-0.022295
RPL36	-0.022270
DDAH1	-0.022219
FLNC	-0.022171
RPL27	-0.022124
UCP2	-0.022092
RPS7	-0.022090
PEA15	-0.021782
PON2	-0.021536
CSRP1	-0.021502
HDGF	-0.021345
SMS	-0.021319
PPM1D	-0.021301
CD81	-0.021300
ECHS1	-0.021290
SERPINE1	-0.021215
SEPT9	-0.021044
TRAM1	-0.020981
MTCH2	-0.020917
KRT17	-0.020914
PRNP	-0.020881
EXT1	-0.020846
CNN1	-0.020786
COL4A1	-0.020714
MTHFD1	-0.020682
TAF6	-0.020678
RPL11	-0.020543
RPS27L	-0.020529
CAV1	-0.020528
LGALS3	-0.020519
MYC	-0.020501
GLTSCR2	-0.020480
P4HB	-0.020369
GRSF1	-0.020256
AHCY	-0.020243
EMP3	-0.020128
BCL2L1	-0.020114
SNRPD2	-0.020099
ABLIM1	-0.020075
CHD4	-0.020061
SNRPF	-0.020055
RPL19	-0.019949
ERP29	-0.019779
ANXA5	-0.019566
SF1	-0.019475
LDOC1	-0.019446
CCT2	-0.019416
CPSF1	-0.019335
RAP2B	-0.019310
TPM2	-0.019270
RPS25	-0.019130
VDAC3	-0.019103
GALNT2	-0.019021
HNRNPA2B1	-0.018797
TUBB3	-0.018796
FUT8	-0.018743
CCNI	-0.018681
SHC1	-0.018656
MBOAT7	-0.018193
FIBP	-0.018156
TGIF1	-0.018114
DFNA5	-0.018109
RTN4	-0.018095
TNS3	-0.018058
DSTN	-0.018039
NPM1	-0.018026
PSAP	-0.017868
EIF4A1	-0.017848
LTBP2	-0.017842
RNASET2	-0.017827
PRAME	-0.017802
PHC1	-0.017650
GNAI1	-0.017516
ACTN4	-0.017502
TMED9	-0.017404
MTCH1	-0.017331
GRB10	-0.017242
PFN1	-0.017237
GSTM2	-0.017199
S100A11	-0.017154
RPS9	-0.017051
IL18	-0.017033
LASP1	-0.016897
PGK1	-0.016812
PABPC4	-0.016774
YWHAH	-0.016720
ZNF395	-0.016709
PHB2	-0.016704
CCNG1	-0.016646
TMEM258	-0.016614
PFKM	-0.016602
ZYX	-0.016592
TSPO	-0.016552
TXN	-0.016494
RPL29	-0.016493
ATP5B	-0.016482
COTL1	-0.016248
RAB13	-0.016015
ARF3	-0.016010
ZFP36L1	-0.015881
RCN2	-0.015846
PPP3CA	-0.015746
SNRPA	-0.015743
ATIC	-0.015719
BAI2	-0.015707
PAM	-0.015682
ERBB2IP	-0.015598
ME2	-0.015585