!direction	-1
!num_genes	422
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!cell_type	MCF7cells
!pert_name	ICI-182,780(Fulvestrant)
!pert_id	PubChemCID:104741
!organism	human
!pert_type	chemical
!end_metadata
MYBL1	-0.059100
CDH26	-0.054705
MCM10	-0.051999
DTL	-0.050518
CDC6	-0.047097
CENPU	-0.046244
DDIAS	-0.044315
PGR	-0.043846
CDH26	-0.043279
RAMP3	-0.043215
DTL	-0.042721
BLM	-0.042482
CDC6	-0.042452
RBM24	-0.042368
MGP	-0.042306
NEIL3	-0.042108
CDC45	-0.041300
CCNE2	-0.041256
EGR3	-0.041146
CXCL12	-0.040013
MCM10	-0.039387
RMST	-0.038358
DSCC1	-0.037886
GINS2	-0.037717
BRCA2	-0.037604
EXO1	-0.037596
PGR	-0.037571
TYMS	-0.037519
SPC25	-0.037387
RAD54L	-0.037227
WDR76	-0.037086
GINS4	-0.037047
HELLS	-0.037005
WDHD1	-0.036805
ZNF367	-0.036726
PDZK1	-0.036339
SGK3	-0.036021
CALCR	-0.035995
FANCI	-0.035851
RAD51AP1	-0.035847
UHRF1	-0.035713
LINC01016	-0.035701
SYTL5	-0.035630
ORC1	-0.035614
PLK4	-0.035573
RRM2	-0.035484
CXCL12	-0.035460
TCF19	-0.035299
FANCI	-0.035202
BRCA2	-0.035115
CENPU	-0.034992
IGSF1	-0.034884
CENPI	-0.034875
MTFR2	-0.034861
C18orf54	-0.034792
BRCA1	-0.034580
ANLN	-0.034498
RRM2	-0.034426
TMPRSS3	-0.034400
CDC25A	-0.034389
PLK4	-0.034354
RBL1	-0.034283
FANCI	-0.034102
MND1	-0.034047
MYBL2	-0.033978
ESPL1	-0.033956
BUB1	-0.033874
CDC25A	-0.033841
CEP128	-0.033744
WDHD1	-0.033499
CAV1	-0.033492
CDCA5	-0.033481
ELOVL2	-0.033429
CENPM	-0.033407
AURKB	-0.033299
SYTL5	-0.033288
TK1	-0.033280
POLQ	-0.033183
OIP5	-0.033175
SDK2	-0.033135
TK1	-0.033129
CDCA7	-0.033070
MKI67	-0.032982
E2F7	-0.032953
FHL1	-0.032931
SPC24	-0.032902
MCM10	-0.032899
AGR2	-0.032886
C1orf226	-0.032840
NCAPH	-0.032692
IL17RB	-0.032692
MNS1	-0.032548
SHCBP1	-0.032523
KLK11	-0.032495
CASC5	-0.032480
ATAD2	-0.032475
RBP7	-0.032365
WDHD1	-0.032291
MCM5	-0.032222
MCM4	-0.032144
SKA3	-0.032050
FEN1	-0.032005
AURKB	-0.031999
NPY5R	-0.031955
ASCL1	-0.031933
CHEK1	-0.031843
CENPU	-0.031790
CEP55	-0.031699
CDK1	-0.031688
CENPK	-0.031675
RAD51	-0.031661
CDK1	-0.031507
PBK	-0.031496
MKI67	-0.031400
CENPI	-0.031330
PRSS23	-0.031316
TMEM64	-0.031305
CHEK1	-0.031231
GREB1	-0.031139
KIF15	-0.031106
TICRR	-0.031049
PKIB	-0.030979
TYMS	-0.030843
C5orf34	-0.030791
SERPINA3	-0.030771
KIF2C	-0.030673
C8orf46	-0.030632
FHL1	-0.030595
RAB31	-0.030583
MKI67	-0.030515
GINS3	-0.030486
MKI67	-0.030419
JAK2	-0.030372
CCNE2	-0.030352
ATAD2	-0.030245
BIRC5	-0.030244
TRIP13	-0.030156
SGOL1	-0.030151
LINC00673	-0.030147
ESPL1	-0.030067
C1orf112	-0.029992
PKIB	-0.029862
CDCA3	-0.029847
CAV1	-0.029824
COL21A1	-0.029799
KIAA0101	-0.029770
DEPDC1	-0.029735
CDCA2	-0.029711
RAB31	-0.029696
TMEM194A	-0.029661
NDC80	-0.029646
GTSE1	-0.029621
SFXN2	-0.029547
CHAF1A	-0.029268
SGK1	-0.029229
GINS3	-0.029189
COL12A1	-0.029187
HELLS	-0.029076
RAB31	-0.029020
POLE2	-0.029012
FOXM1	-0.028985
CCNA2	-0.028900
CDT1	-0.028857
NUSAP1	-0.028801
HELLS	-0.028688
ATAD2	-0.028661
NCAPG2	-0.028613
SYTL4	-0.028610
ATAD2	-0.028596
E2F1	-0.028588
FANCD2	-0.028539
MELK	-0.028533
POLQ	-0.028510
SPAG5	-0.028414
CCDC150	-0.028405
CEP152	-0.028333
MCM4	-0.028269
MAD2L1	-0.028244
ANLN	-0.028216
CDC25C	-0.028184
ASF1B	-0.028171
UBE2C	-0.028147
LIG1	-0.028139
NCAPG	-0.028091
E2F8	-0.028074
SLC39A8	-0.028045
TOP2A	-0.028018
ELOVL2	-0.028006
CHEK1	-0.027967
HJURP	-0.027905
CENPN	-0.027659
CLSPN	-0.027610
E2F2	-0.027506
CENPE	-0.027500
CENPW	-0.027499
CDCA8	-0.027497
FEN1	-0.027472
MCM5	-0.027366
MCM2	-0.027359
PRSS23	-0.027321
PCNA	-0.027300
CDK1	-0.027282
BRIP1	-0.027279
BRCA1	-0.027220
POLA2	-0.027177
C1QTNF6	-0.027120
KIF23	-0.027095
WDR76	-0.027085
NEK2	-0.027035
GMNN	-0.026982
TOP2A	-0.026971
NUF2	-0.026903
KIF18B	-0.026772
BUB1B	-0.026742
JAK2	-0.026721
CDK1	-0.026663
HELLS	-0.026573
LOC81691	-0.026525
RFC3	-0.026452
ADCY1	-0.026442
H2AFX	-0.026440
NCAPG	-0.026438
MTFR2	-0.026311
SPDL1	-0.026300
IGSF1	-0.026284
RFC4	-0.026207
ZGRF1	-0.026170
WHSC1	-0.026149
AGR3	-0.026128
SYNPO2	-0.026066
OLFM1	-0.025954
KIF2C	-0.025923
FIGNL1	-0.025876
BRIP1	-0.025863
FBXO5	-0.025853
MCM4	-0.025784
DNA2	-0.025709
TTK	-0.025667
ERCC6L	-0.025636
COL12A1	-0.025634
FAM111B	-0.025607
IQGAP3	-0.025605
FANCA	-0.025567
TYMS	-0.025535
PCP4	-0.025483
CIT	-0.025454
C4orf46	-0.025421
BTG3	-0.025420
BUB1	-0.025410
CDC7	-0.025388
UBE2T	-0.025323
BTG3	-0.025318
ORC6	-0.025316
CDCA3	-0.025284
DEPDC1	-0.025261
FAM161A	-0.025165
TMEM194A	-0.025114
CHEK2	-0.025065
MSMB	-0.025014
GINS1	-0.024964
FAM83D	-0.024868
BARD1	-0.024863
RFC5	-0.024800
CEP152	-0.024800
SKA1	-0.024745
TAF5	-0.024724
MASTL	-0.024720
CENPF	-0.024703
AREG	-0.024645
FANCA	-0.024552
KNTC1	-0.024535
SLC39A8	-0.024523
IL17RB	-0.024456
IGFBP4	-0.024456
SLC39A8	-0.024420
C9orf40	-0.024334
CTSD	-0.024285
SMC2	-0.024145
FABP5	-0.024143
SLC1A2	-0.024131
KIF11	-0.024075
TACC3	-0.024025
POLD3	-0.024018
KIF18A	-0.024010
LOC389831	-0.023981
CENPN	-0.023977
PRIM1	-0.023967
NEK2	-0.023948
MCM3	-0.023915
C3orf70	-0.023760
COL12A1	-0.023759
ARHGEF28	-0.023751
DEPDC1	-0.023739
CHRNA5	-0.023708
RNASEH2A	-0.023701
WISP2	-0.023650
DEPDC1	-0.023638
STMN1	-0.023634
CHAF1B	-0.023631
MSMB	-0.023622
TIMELESS	-0.023591
CCNA2	-0.023529
PTPRG-AS1	-0.023485
ANKRD32	-0.023470
MAD2L1	-0.023419
TPX2	-0.023413
IL17RB	-0.023362
ASPM	-0.023332
RECQL4	-0.023300
MCM7	-0.023297
HIST1H4C	-0.023285
NUSAP1	-0.023280
KCNK5	-0.023267
CTNNAL1	-0.023251
PRC1	-0.023235
SKP2	-0.023232
RERG	-0.023226
OVOS2	-0.023205
RRM1	-0.023200
LHX2	-0.023175
CENPF	-0.023137
RERG	-0.023124
PLK1	-0.023096
PLK4	-0.023070
FIGNL1	-0.023048
LOC389831	-0.023045
DSN1	-0.022957
FANCB	-0.022899
CENPH	-0.022845
DLGAP5	-0.022795
PMAIP1	-0.022790
ZWILCH	-0.022721
PKMYT1	-0.022710
DENND1A	-0.022693
KIF23	-0.022531
ATRNL1	-0.022527
RMI2	-0.022509
CDC25A	-0.022495
GLA	-0.022438
TMEM107	-0.022420
GSG2	-0.022415
SERPINA1	-0.022409
PARPBP	-0.022373
MCM6	-0.022335
NASP	-0.022320
PHLDA1	-0.022318
CKAP2L	-0.022297
EME1	-0.022295
TMEM64	-0.022293
TMEM164	-0.022262
DUT	-0.022230
CENPJ	-0.022198
DHFR	-0.022150
KIAA1524	-0.022131
CENPA	-0.022100
KIF14	-0.022032
BMP5	-0.022029
CA2	-0.022023
KIF14	-0.021868
CENPQ	-0.021861
MYB	-0.021855
ARHGAP36	-0.021854
FHL1	-0.021823
GTSE1	-0.021801
CDK2	-0.021781
CYP24A1	-0.021696
CDKN3	-0.021658
RBL1	-0.021583
CDC20	-0.021565
BARD1	-0.021553
CDK2	-0.021550
KIF4A	-0.021521
AGR2	-0.021462
FAM64A	-0.021452
ADCY1	-0.021429
FANCD2	-0.021425
CKS1B	-0.021417
SGOL2	-0.021357
TMEM164	-0.021348
PTGES	-0.021108
CDKN2C	-0.021101
PAQR4	-0.021100
NRM	-0.021085
ARHGAP11A	-0.021073
LOC81691	-0.021023
CDT1	-0.021021
TUBB	-0.021005
CENPN	-0.020992
CALCR	-0.020979
MCM8	-0.020973
PHF19	-0.020958
CDCA7	-0.020932
GPX8	-0.020907
TMEM164	-0.020893
MCM4	-0.020848
LRR1	-0.020821
COCH	-0.020815
THSD4	-0.020812
CDKN3	-0.020802
EP300-AS1	-0.020794
TUBB	-0.020778
TMEM201	-0.020771
FKBP5	-0.020767
RFC2	-0.020765
SOX3	-0.020761
KIFC1	-0.020744
C18orf54	-0.020705
HMMR	-0.020680
TOP2A	-0.020664
EPS15L1	-0.020607
LMNB2	-0.020560
CBX5	-0.020548
AUNIP	-0.020510
DONSON	-0.020505
TIAM1	-0.020473
STIL	-0.020466
NUP62CL	-0.020447
DHFR	-0.020432
ZWINT	-0.020388
GREB1	-0.020376
MCM7	-0.020350
PSMC3IP	-0.020345