!direction	-1
!num_genes	173
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Estradiol
!smiles	CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
!drugbank_id	DB00783
!pubchem_cid	5757
!cell_type	Endothelial cells (cultured umbilical vein endothelial cells) - treated with 1 nmol/L estradiol for 24 hours
!organism	human
!end_metadata
RPS25	-0.085019
RPL6	-0.071620
TUBA1A	-0.070447
CNN3	-0.066072
RASSF3	-0.060392
HAPLN3	-0.059344
RPL39	-0.059275
KIAA0485	-0.059160
ZNF598	-0.057000
RPL27	-0.056643
RPL38	-0.056428
MYH16	-0.055038
EIF3H	-0.052059
AQP9	-0.051969
RPL34	-0.049923
RPS4Y1	-0.049569
CCL2	-0.049130
HNRNPH1	-0.048559
RPL24	-0.047482
COX7A2	-0.047183
PDGFA	-0.046573
ITGAV	-0.046434
EIF3E	-0.045848
LAPTM4A	-0.045197
RPS13	-0.045017
C6orf62	-0.044976
RND3	-0.044759
APP	-0.044397
GJA1	-0.044184
CRIM1	-0.044062
GNG11	-0.043919
USMG5	-0.043801
RAB13	-0.043763
RPL23	-0.042832
RPS14P3	-0.042165
IAH1	-0.041622
PARK7	-0.041557
RPS29	-0.041437
EFNA1	-0.040795
SRP14	-0.040515
NUMBL	-0.040212
ESM1	-0.040093
ATP1B1	-0.039409
CRACR2B	-0.039138
SEC22B	-0.039086
IRF2BPL	-0.038206
MORF4L1	-0.037214
FRMD7	-0.036500
NPM1	-0.036350
RPS4X	-0.036254
YWHAG	-0.035959
MAFF	-0.035177
AKAP12	-0.035063
RALA	-0.034706
EGR1	-0.034337
SEP15	-0.033917
RPL22	-0.033646
RPS21	-0.032947
B2M	-0.032830
PPP1CB	-0.032630
RPL5	-0.032604
LOC340085	-0.032530
ND6	-0.031637
TM4SF1	-0.031421
SRGAP2C	-0.031351
PSMA4	-0.031188
LOC100996255	-0.031171
PLS3	-0.030782
NACAP1	-0.030706
EBNA1BP2	-0.030693
GNG10	-0.030274
TBCA	-0.030141
VMP1	-0.029983
CDY1	-0.029978
RIN2	-0.029593
SLC30A2	-0.029393
NME7	-0.029309
HGFAC	-0.029048
RPL14	-0.028949
MYL12A	-0.028493
YWHAE	-0.028121
EMC6	-0.028065
C8orf4	-0.028001
ADM	-0.027855
NACA	-0.027815
NDUFC2	-0.027293
RPS3A	-0.027226
CALM2	-0.026946
RSL24D1	-0.026845
GOLGA8H	-0.026798
SUMO4	-0.026710
EOGT	-0.026650
DAP3	-0.026545
PPP1CC	-0.026181
LOC100289333	-0.026091
LINC00094	-0.025979
PCDHGA8	-0.025949
RPL9	-0.025898
UQCRB	-0.025881
MYL6	-0.025876
RPL22L1	-0.025828
NDUFA4	-0.025165
ARGLU1	-0.025145
ATG3	-0.024885
UNC50	-0.024646
RNF11	-0.024613
CDH13	-0.024571
LINC00880	-0.024479
SMURF2	-0.024389
ATPIF1	-0.024115
COCH	-0.024064
WSB2	-0.023981
ZNF490	-0.023935
HIST1H4C	-0.023933
TMA7	-0.023822
RAB1A	-0.023493
MSH3	-0.023451
TMSB15A	-0.023324
CHP1	-0.023242
NUCKS1	-0.023230
HMGN1	-0.023085
HOXB2	-0.023013
TCF7	-0.022994
TNPO1	-0.022796
ANXA1	-0.022636
RPL36AL	-0.022615
TOMM20	-0.022551
GAS5	-0.022419
PPP3CA	-0.022317
GADD45A	-0.022278
NPTN	-0.022244
STMN1	-0.022187
C17orf58	-0.022152
DDX21	-0.022147
ANXA2P2	-0.022045
H1FOO	-0.022026
PTCHD1	-0.021877
RPSA	-0.021731
SRGN	-0.021634
SSBP3-AS1	-0.021591
SEC11A	-0.021577
PCMTD1	-0.021525
TFPI	-0.021480
SKP1	-0.021454
EEF1B2	-0.021340
KLF10	-0.021212
XPOT	-0.021194
RNH1	-0.021088
NOP58	-0.021014
SF3B5	-0.020887
WTAP	-0.020826
EIF2S2	-0.020774
RPS7	-0.020739
PLIN3	-0.020723
NARS	-0.020687
CLDN19	-0.020639
MAP1B	-0.020523
DSTNP2	-0.020518
ZNF320	-0.020465
MYCT1	-0.020432
ANXA7	-0.020428
YWHAQ	-0.020402
SUMO2	-0.020316
RPS15A	-0.020253
C6orf48	-0.020077
UFSP1	-0.020074
BLOC1S2	-0.020036
DUSP26	-0.019890
RPL27A	-0.019768
FTH1	-0.019763
MRPL17	-0.019737
NAP1L1	-0.019679
ANXA2	-0.019656