!direction	-1
!num_genes	252
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	actinomycin D
!smiles	CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
!pubchem_cid	2019
!cell_type	A549 lung cancer cells
!organism	human
!end_metadata
UBC	-0.338846
SLC38A2	-0.247670
DKK1	-0.240458
ND2	-0.187946
ID1	-0.166218
DDIT4	-0.164273
AMIGO2	-0.162785
MIR21	-0.127964
COX2	-0.116427
TUBA1C	-0.107034
CEBPB	-0.099032
IRS2	-0.098740
ERRFI1	-0.094205
UBB	-0.088456
MAT2A	-0.085771
HERPUD1	-0.081697
C8orf4	-0.078213
TUBA1B	-0.075495
BTG1	-0.070327
IER3	-0.069444
TOB1	-0.068945
DUSP4	-0.066661
IRF2BPL	-0.065784
MTUS1	-0.063341
MAPK6	-0.063126
GCNT3	-0.062255
UQCRFS1	-0.062048
APEX1	-0.055081
TNFRSF1A	-0.052842
RPL39	-0.052309
KCNJ2	-0.052078
NTS	-0.052030
TRIB3	-0.051098
PKDCC	-0.048671
NRIP1	-0.048579
TSC22D1	-0.047040
DUSP1	-0.045802
SIK1	-0.045635
SRXN1	-0.044637
SLC7A5	-0.043538
IER2	-0.042800
CDKN1B	-0.042669
GARS	-0.041966
BASP1	-0.041288
PLK2	-0.039882
ALX1	-0.039737
FLRT3	-0.038994
ATF4	-0.038560
RHPN2	-0.038417
EIF1	-0.038213
FTL	-0.037071
BAMBI	-0.035763
ZFAND5	-0.034345
SGK223	-0.033977
RGS2	-0.033173
H3F3B	-0.033063
FAM107B	-0.032946
EDN1	-0.032532
ID3	-0.032513
NET1	-0.032191
CBX4	-0.032015
AHR	-0.031648
PTRH2	-0.031307
CCT2	-0.031275
PDK4	-0.031162
YWHAG	-0.031001
DDX5	-0.030680
RND3	-0.030608
PCBP1	-0.030578
IMP3	-0.030157
PDE4B	-0.029919
ZNF146	-0.029898
GPCPD1	-0.029632
YTHDF1	-0.029344
C1orf106	-0.029258
TUBA1A	-0.029066
TAF7	-0.028727
ADM	-0.028667
GOLPH3	-0.028627
PPP1R15B	-0.028248
PUM1	-0.028183
SEC24B	-0.027871
HSPA8	-0.027697
MMADHC	-0.027460
PPP1CC	-0.027080
PFKFB3	-0.027078
PCNA	-0.026963
NFKBIA	-0.026957
ELF3	-0.026915
SRP68	-0.026843
RAN	-0.026776
BHLHE40	-0.026509
TXNRD1	-0.026473
PSMC6	-0.025743
IRF2BP2	-0.025730
KLF10	-0.025517
GNL3	-0.025516
NOL11	-0.025443
CEBPZ	-0.025321
METTL23	-0.025296
NOB1	-0.025252
IER5	-0.025165
RNF139	-0.025110
C14orf119	-0.025058
NDUFAB1	-0.024975
LINC00473	-0.024814
XBP1	-0.024699
MRPL15	-0.024680
ZNF217	-0.024468
FAM46A	-0.024455
MRPL10	-0.024437
RARS	-0.024419
NEDD9	-0.024385
SRP19	-0.024308
RNF4	-0.024190
PTGS2	-0.024135
SSR2	-0.024125
SGK1	-0.023947
EIF2S2	-0.023758
NOP58	-0.023675
TRIM16	-0.023616
NR3C1	-0.023459
TGFBR2	-0.023389
PNRC1	-0.023378
DDX47	-0.023273
SEPHS2	-0.023028
TNS3	-0.022982
ARF6	-0.022749
LHX8	-0.022695
DHX32	-0.022603
CDK7	-0.022572
DNAJB1	-0.022564
AIMP2	-0.022526
RHOBTB1	-0.022504
HIF1A	-0.022476
MID1	-0.022403
ZNRF3	-0.022212
MYC	-0.022164
XPOT	-0.022107
ODC1	-0.022010
PTPRO	-0.021859
GDF15	-0.021705
YTHDF2	-0.021696
NNMT	-0.021530
SCAF8	-0.021493
RRS1	-0.021350
LINC00657	-0.021293
WAC	-0.021287
DNTTIP2	-0.021178
ZCCHC8	-0.021176
ADNP	-0.021117
COX1	-0.020889
DNAJB9	-0.020863
TUBB4B	-0.020805
ZNF281	-0.020715
MFHAS1	-0.020545
RSL24D1	-0.020544
GOLGA5	-0.020315
TRMT10C	-0.020033
MIS12	-0.020024
DDIT3	-0.019981
MRFAP1L1	-0.019907
PLA2G4A	-0.019821
TUBB	-0.019800
SHOC2	-0.019792
NCOA7	-0.019781
TSKU	-0.019611
HNRNPA1	-0.019422
KPNA2	-0.018995
RRAGA	-0.018861
PSMG2	-0.018858
NXT1	-0.018599
RNF19A	-0.018536
CTCF	-0.018522
VEZF1	-0.018492
RNF111	-0.018425
FAM220A	-0.018412
EIF4A3	-0.018407
TXNIP	-0.018330
TUBB2A	-0.018296
CEBPG	-0.018289
TIPARP	-0.018278
KLHDC2	-0.018199
GRAMD1B	-0.018159
RNF145	-0.018129
ZSWIM6	-0.018127
TJP1	-0.018059
AVPI1	-0.018048
SIRT1	-0.017993
CDC25B	-0.017864
PSMD12	-0.017794
HILPDA	-0.017788
TBK1	-0.017597
NDEL1	-0.017489
WDR82	-0.017330
C1orf131	-0.017290
TUBB3	-0.017246
RNF113A	-0.017206
FAM214A	-0.017199
SLC30A1	-0.017118
MLPH	-0.017042
RIN2	-0.017039
HHEX	-0.017004
SOX4	-0.016876
NFE2L2	-0.016760
ZFP36	-0.016747
GADD45A	-0.016733
CHSY1	-0.016731
ETF1	-0.016724
NPM1	-0.016688
MISP	-0.016575
SRSF7	-0.016524
PUM2	-0.016522
LINC00493	-0.016457
KANSL1	-0.016435
LDOC1L	-0.016416
PHF23	-0.016410
TRA2B	-0.016362
TSPYL5	-0.016350
IER5L	-0.016346
DNAJA1	-0.016345
KLF5	-0.016302
TOX3	-0.016275
RPL30	-0.016245
YTHDF3	-0.016202
RPL27	-0.016110
KRCC1	-0.016075
BIRC2	-0.016069
RSRC2	-0.016047
GTF2B	-0.016026
ID2	-0.016005
NUP35	-0.015985
ARCN1	-0.015978
ARF4	-0.015973
PLCXD1	-0.015956
DEDD2	-0.015941
NUFIP2	-0.015926
GNA13	-0.015900
FNDC3B	-0.015825
SLC3A2	-0.015798
EIF3A	-0.015785
CCDC12	-0.015760
SRP9	-0.015672
FADD	-0.015662
MEIS2	-0.015650
EIF4A2	-0.015648
ACBD3	-0.015630
GOLPH3L	-0.015605
LYSMD3	-0.015576
PPP1R8	-0.015540
SMNDC1	-0.015526
MPHOSPH10	-0.015496