!direction	-1
!num_genes	276
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	PubChemCID:5757
!cell_type	MCF7cells
!organism	human
!end_metadata
SLC2A3	-0.132827
CDH10	-0.099070
PLEKHS1	-0.098286
VTCN1	-0.095239
SGCE	-0.094627
GJA1	-0.088988
NDRG1	-0.086386
SIGLEC6	-0.072982
ZNF175	-0.072672
EPAS1	-0.067224
SPNS2	-0.059075
PAPSS2	-0.058800
BCAS1	-0.058589
INHBB	-0.056417
SERPINE2	-0.055920
CEMIP	-0.055912
S100A9	-0.055132
MMP10	-0.055030
ELF3	-0.053588
ACTA2	-0.052651
PYGL	-0.050884
SPATS2L	-0.050878
NTN4	-0.049149
LAMB1	-0.049079
CTGF	-0.048376
VGLL1	-0.047518
RDX	-0.046422
STC1	-0.044823
TMEM45B	-0.043179
LIMCH1	-0.041670
NPHP3	-0.041140
S100P	-0.041028
ADM	-0.040695
KRT24	-0.040328
TNFRSF21	-0.039975
WNT10B	-0.039730
HEY1	-0.039523
EFHD1	-0.038884
GDF15	-0.038847
RFTN1	-0.038518
DIRC3	-0.037216
LINC00294	-0.037082
CAV1	-0.036884
KIAA1147	-0.036696
ZNF91	-0.036309
MIR21	-0.036179
DNASE1	-0.036081
NELL2	-0.036005
SAT1	-0.035613
MFSD6	-0.035205
ANKRD37	-0.035119
CREB3L2	-0.035070
ACAD11	-0.034957
NT5C2	-0.034794
IRF1	-0.034707
CDK6	-0.033793
PXDN	-0.033543
GABRP	-0.033464
ATP1B1	-0.033336
FAM214A	-0.033182
PRKCA	-0.033174
DRAM1	-0.032983
PRICKLE2	-0.032930
MT1X	-0.032842
UBA5	-0.032772
GABBR2	-0.032744
MOB3B	-0.032265
PKIA	-0.032226
TSPAN3	-0.031791
DHRS3	-0.031751
NXPH1	-0.031456
LHFP	-0.031265
LYN	-0.031201
STAMBPL1	-0.031083
TMEM123	-0.030937
CAV2	-0.030220
IRS1	-0.030218
S100A4	-0.030183
PROM1	-0.029990
MAN1A1	-0.029482
CITED2	-0.029399
MALL	-0.029217
TPBG	-0.029171
PSMB10	-0.029134
ASPH	-0.028782
GALNT12	-0.028770
TGFBI	-0.028410
CYP1B1	-0.028326
ERO1L	-0.028141
PGM1	-0.028038
LMO2	-0.028031
LXN	-0.028005
GCNT1	-0.027665
OLFML3	-0.027592
PAM	-0.027297
TIGD2	-0.027084
MAB21L3	-0.026966
DOCK11	-0.026626
ZFP36L2	-0.026481
FURIN	-0.026457
NR4A2	-0.026355
UGDH	-0.026117
BNIP3L	-0.025952
ST3GAL4	-0.025600
TMC4	-0.025163
PMEPA1	-0.025120
FOSB	-0.024756
PKP2	-0.024754
ALDOC	-0.024680
PCGF5	-0.024638
CAMK2N1	-0.024627
LARP6	-0.024606
HBEGF	-0.024469
ATXN1	-0.024434
SH3YL1	-0.024414
MPZL2	-0.024385
CDH3	-0.024304
MAP7D2	-0.024279
KCNS3	-0.024276
TSPAN5	-0.023920
FAM13A	-0.023856
VASN	-0.023806
GPR126	-0.023798
BBX	-0.023594
EDARADD	-0.023294
PLOD2	-0.023115
TTC31	-0.023107
SH3GL3	-0.022988
HES2	-0.022978
PTGFRN	-0.022955
HMCN1	-0.022805
TPM2	-0.022796
MT1A	-0.022699
INHA	-0.022582
EGLN3	-0.022482
MBNL2	-0.022478
PPP2R2A	-0.022376
FAM189A1	-0.022375
BAIAP2L1	-0.022367
FGD3	-0.022301
C8orf4	-0.022289
IGFBP5	-0.022284
WNT5A	-0.022258
ARNT2	-0.022246
QSOX1	-0.022240
IGFBP3	-0.022221
HK2	-0.022014
PRPS1	-0.021921
GOLM1	-0.021902
GPR160	-0.021899
FAM105A	-0.021868
IGF2BP2	-0.021852
COBLL1	-0.021822
ERC2	-0.021809
LPP	-0.021799
LIN7A	-0.021774
VSIG10L	-0.021676
CTNND2	-0.021648
GLRX	-0.021508
PDLIM5	-0.021507
SASH1	-0.021497
TFAP2A	-0.021399
PCGF1	-0.021351
RAPGEF4	-0.021331
PEG10	-0.021284
TCP11L1	-0.021256
SNORD12C	-0.021216
VAMP8	-0.021135
BCAS3	-0.021072
SLC41A2	-0.021051
MT2A	-0.021047
CUEDC1	-0.020986
STK39	-0.020932
COPS7B	-0.020842
CYSRT1	-0.020808
NMI	-0.020794
TRIP10	-0.020790
DDB2	-0.020784
WBP1	-0.020783
MLPH	-0.020600
TSPAN9	-0.020594
TMPRSS2	-0.020499
CCNO	-0.020496
LINC01293	-0.020403
ZNF185	-0.020361
SSFA2	-0.020344
SLC2A14	-0.020335
ALDH1A3	-0.020328
TSPAN15	-0.020305
FHL2	-0.020265
SH3BP4	-0.020260
SESTD1	-0.020229
IDH1	-0.020195
ITPRIPL2	-0.020032
RRAGD	-0.019974
BCL6	-0.019966
SNORD89	-0.019937
BACE2	-0.019933
BASP1	-0.019931
UPK2	-0.019879
LAPTM4A	-0.019796
IL12A	-0.019791
TANC2	-0.019763
RNF145	-0.019761
RILPL2	-0.019727
KIAA1210	-0.019698
ENPP1	-0.019676
PFKFB3	-0.019465
METTL22	-0.019457
FNDC3B	-0.019452
SPIRE2	-0.019415
SCRN1	-0.019392
UNC13D	-0.019331
CCNYL1	-0.019291
CYB5A	-0.019263
IL1R1	-0.019256
SPATA18	-0.019070
MARCKS	-0.019003
CIR1	-0.019001
FZD2	-0.018971
GNG4	-0.018969
MTURN	-0.018944
SPRED1	-0.018924
COL5A2	-0.018852
ITGB6	-0.018843
CXCR4	-0.018836
ATP8B4	-0.018817
LOC100129550	-0.018754
NDRG2	-0.018701
ZKSCAN1	-0.018661
CABLES1	-0.018632
FTH1	-0.018566
TRIP12	-0.018503
NPNT	-0.018433
RRAS	-0.018432
SCUBE2	-0.018334
TMEM131	-0.018301
KCNK2	-0.018291
MT1F	-0.018290
VEGFC	-0.018279
DIO2	-0.018274
B4GALT5	-0.018260
ANKRD13A	-0.018253
SERPINA11	-0.018227
PTMA	-0.018208
AUP1	-0.018190
PROM2	-0.018188
TRPC1	-0.018180
LYPD6B	-0.018172
ITGA5	-0.018147
CCDC115	-0.018136
F2RL1	-0.018114
SDCBP	-0.018060
PARP4	-0.018041
ANXA1	-0.018039
MEIS1	-0.018034
PDE4D	-0.018021
YPEL3	-0.018016
PRCP	-0.017997
ELL2	-0.017995
SH2D4A	-0.017915
SORL1	-0.017788
SPACA6P	-0.017730
GLIPR2	-0.017695
ABCA4	-0.017589
ADA	-0.017588
YPEL2	-0.017588
ST3GAL1	-0.017577
NBEA	-0.017541
NAV2	-0.017537
ACSL3	-0.017524
WWC2	-0.017491
ABCC3	-0.017433
SMCO4	-0.017380
HDHD1	-0.017379
PLCB1	-0.017379