!direction	-1
!num_genes	242
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Heroin
!smiles	CC(=O)OC1C=CC2C3CC4=C5C2(C1OC5=C(C=C4)OC(=O)C)CCN3C
!drugbank_id	DB01452
!pubchem_cid	5462328
!cell_type	striatum, day 1 treatment
!organism	mouse
!end_metadata
S100A5	-0.298164
OMP	-0.132686
CDHR1	-0.119630
ND6	-0.108205
SLC6A13	-0.057768
CALB2	-0.057649
PMCH	-0.053376
ARC	-0.052066
TH	-0.048571
SLC6A3	-0.041340
TRH	-0.040415
SP8	-0.039449
PRKCD	-0.037468
AEBP1	-0.036647
PCP2	-0.036280
GNG4	-0.034201
HSPA5	-0.032565
EGR2	-0.032397
NPAS4	-0.031616
PCP4	-0.030641
ND1	-0.027241
EMP2	-0.027114
JUNB	-0.026097
HLA-DRB5	-0.023907
SLC13A4	-0.023720
S100A6	-0.023398
BGN	-0.023308
ZIC1	-0.022806
REC8	-0.022580
DRD2	-0.022564
FRZB	-0.022369
ARHGAP33	-0.022270
NPPA	-0.022189
CRTC2	-0.022124
ECEL1	-0.022085
PFKFB3	-0.022075
SMARCA5	-0.022064
DDB1	-0.021799
DCN	-0.021768
ND5	-0.021513
CACYBP	-0.021320
TOP2B	-0.021293
SERPING1	-0.020877
DLX1	-0.020733
ITGB4	-0.020714
KCNE2	-0.020517
GATA4	-0.020234
SCGN	-0.019637
SHB	-0.019540
RAPGEF3	-0.019409
OLAH	-0.019207
HLA-DQA1	-0.018936
PRKRIR	-0.018717
C14orf80	-0.018669
SLC6A12	-0.018588
DOK3	-0.018572
CD74	-0.018508
HMGB4	-0.018319
PLEKHD1	-0.018181
SIX6	-0.018068
C11orf74	-0.017944
KLK6	-0.017743
TROAP	-0.017664
YWHAQ	-0.017622
CTSD	-0.017582
WIPF2	-0.017557
OPALIN	-0.017543
NKAIN4	-0.017526
SLC22A7	-0.017196
FRMD7	-0.017196
SERPINB8	-0.017155
TNNT1	-0.017020
C17orf70	-0.016962
OTOS	-0.016959
OTOP2	-0.016937
AMT	-0.016902
GFAP	-0.016845
TSPAN13	-0.016689
GPR68	-0.016533
SOX8	-0.016497
PLOD1	-0.016389
GPR153	-0.016188
FGF23	-0.016181
BSX	-0.016144
DLX2	-0.015986
OGN	-0.015963
ST6GALNAC2	-0.015889
LZTS1	-0.015759
FNDC4	-0.015475
FPR2	-0.015455
FAM101B	-0.015454
TPT1	-0.015444
ZDHHC5	-0.015422
IGSF1	-0.015355
CNP	-0.015324
SNAI3	-0.015304
SPRTN	-0.015197
LZIC	-0.015029
TCTA	-0.014985
FOXA1	-0.014917
FAM216B	-0.014915
GLTP	-0.014886
EGR4	-0.014708
SYNDIG1L	-0.014692
NDRG4	-0.014688
UBE2B	-0.014667
PRL	-0.014646
PRPSAP1	-0.014643
KLHL36	-0.014639
EOMES	-0.014576
GAMT	-0.014530
ZNF14	-0.014473
CMBL	-0.014420
RAB37	-0.014417
SERPINB13	-0.014393
ARID3B	-0.014327
FOS	-0.014318
RGS14	-0.014304
RAD21	-0.014301
ZNF319	-0.014291
TNFSF11	-0.014282
CRYAB	-0.014278
KCNJ2	-0.014262
ITGAL	-0.014244
COPB1	-0.014234
C3orf83	-0.014199
USP28	-0.014162
GNG11	-0.014157
FDXACB1	-0.014041
DIO2	-0.013976
LAG3	-0.013938
SCN1A	-0.013925
SNAPC1	-0.013889
EBF3	-0.013872
SOCS1	-0.013840
SPNS1	-0.013798
TMEM50A	-0.013795
AQP1	-0.013730
HIST1H4K	-0.013712
FREM3	-0.013593
CACNA2D1	-0.013592
IL33	-0.013569
CHI3L1	-0.013567
TFAP4	-0.013562
JUND	-0.013559
ATF5	-0.013493
CYP2S1	-0.013491
PAM	-0.013452
PBK	-0.013440
DDAH2	-0.013420
PTPN5	-0.013341
RIBC1	-0.013326
EIF1AY	-0.013284
ARG2	-0.013232
OR6C74	-0.013152
JAM3	-0.013135
BDH2	-0.013127
PLA2G2D	-0.013114
TJP1	-0.013104
C2orf74	-0.013079
FIBCD1	-0.013062
KCNB1	-0.013042
RIN3	-0.012978
RHBDL2	-0.012967
SCN4B	-0.012926
URB2	-0.012916
PI15	-0.012891
KLHL13	-0.012880
FABP7	-0.012878
RGS8	-0.012865
TRIM59	-0.012848
FAM64A	-0.012739
AKAP8	-0.012738
SERPINH1	-0.012708
ARL4D	-0.012688
CDC37	-0.012682
MICU3	-0.012669
NDP	-0.012634
MYO7A	-0.012589
SLC26A1	-0.012580
SDF2L1	-0.012576
C21orf91	-0.012513
LECT1	-0.012511
ZBTB7A	-0.012482
DUSP1	-0.012471
LIN7C	-0.012471
ZFP1	-0.012470
DYNLRB2	-0.012441
ATP13A5	-0.012412
EPHA4	-0.012408
CFP	-0.012406
OGFOD3	-0.012404
PAM16	-0.012395
DGAT1	-0.012380
CCT5	-0.012377
PCYT1A	-0.012358
C2	-0.012299
COL9A2	-0.012256
PRRG3	-0.012240
EFNA2	-0.012209
LAP3	-0.012183
ALDH1A2	-0.012159
C3	-0.012141
STON2	-0.012138
SIL1	-0.012112
ICOS	-0.012039
TMEM262	-0.012038
KRT26	-0.012037
PER2	-0.012012
RBM24	-0.012009
NFAM1	-0.011999
KCNJ11	-0.011992
GNB2L1	-0.011961
LIPT1	-0.011959
TREML2	-0.011933
KCNE1L	-0.011931
SALL3	-0.011907
PSMA3	-0.011862
SEMA4G	-0.011829
EFNB1	-0.011789
TCF23	-0.011770
GATM	-0.011713
CAPZA1	-0.011706
RHCG	-0.011693
TNS1	-0.011685
MS4A15	-0.011667
PAX6	-0.011665
RASD1	-0.011654
TEKT1	-0.011632
RBBP8NL	-0.011602
FOXB1	-0.011556
MOG	-0.011555
TAS2R41	-0.011552
MYH14	-0.011546
RASD2	-0.011539
GPX6	-0.011535
GTSF1	-0.011520
C8B	-0.011452
FAM196B	-0.011450
ZNF462	-0.011445
PLEKHO1	-0.011440
WFDC8	-0.011371