!direction	-1
!num_genes	280
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Heroin
!smiles	CC(=O)OC1C=CC2C3CC4=C5C2(C1OC5=C(C=C4)OC(=O)C)CCN3C
!drugbank_id	DB01452
!pubchem_cid	5462328
!cell_type	striatum, day 15 withdrawal
!organism	mouse
!end_metadata
TTR	-0.864982
SLC17A7	-0.142175
C2orf40	-0.084386
C8orf46	-0.082589
MYL4	-0.082530
CCK	-0.082232
NRN1	-0.079239
SLC30A3	-0.073489
TBR1	-0.067335
CDHR1	-0.063411
WFDC2	-0.062920
NTN5	-0.060297
SOSTDC1	-0.059975
NEUROD2	-0.049439
STMN1	-0.048554
STX1A	-0.047098
CSHL1	-0.045939
NR4A2	-0.044505
FEZF2	-0.043902
KCNE2	-0.039805
FOLR1	-0.037216
TMEM178A	-0.036191
KL	-0.035449
RPRM	-0.033820
TNNC1	-0.033661
PRL	-0.032724
C17orf96	-0.031365
CCDC3	-0.029869
IPCEF1	-0.029459
CNIH3	-0.029218
CORT	-0.029049
SOWAHB	-0.028939
OLFM1	-0.028697
VIP	-0.028305
CLDN2	-0.028180
NPTX1	-0.028058
GALNT9	-0.026600
HSPB3	-0.026574
DKKL1	-0.026466
S100A5	-0.026288
AQP1	-0.026113
IGFBP2	-0.025700
HKDC1	-0.025621
TEX40	-0.025396
CCKBR	-0.024875
CCL21	-0.024834
RASL10A	-0.024831
NECAB3	-0.024811
RASL11B	-0.024213
CTGF	-0.024041
STAC2	-0.023486
WNT10A	-0.023353
KIAA1239	-0.022970
SLC26A4	-0.022127
MPPED1	-0.020247
SLC13A4	-0.020123
GRP	-0.020019
MEDAG	-0.019821
TCAP	-0.019654
IGFN1	-0.019626
MAS1	-0.019624
ENPP2	-0.019318
TSHZ3	-0.019244
MAF	-0.018987
FAM81A	-0.018847
LINGO1	-0.018652
BHLHE22	-0.018598
FAM19A1	-0.018459
ARHGAP15	-0.018403
NCALD	-0.018368
IGSF21	-0.018347
CRHBP	-0.018209
HLA-DRB5	-0.018046
PRSS12	-0.017859
SSTR2	-0.017784
CD74	-0.017518
S100A10	-0.017459
IGFBP6	-0.017220
HOMER2	-0.017098
TSPYL4	-0.016599
SLC16A8	-0.016465
ST8SIA5	-0.016409
ENC1	-0.016399
TTC9B	-0.016181
SEPT9	-0.015884
GLUL	-0.015720
SERPINI1	-0.015665
FRZB	-0.015665
OTX1	-0.015593
SYT13	-0.015533
ADCYAP1	-0.015273
RSPO3	-0.015145
ND5	-0.015083
RAPGEFL1	-0.014716
MAPK11	-0.014626
FHL2	-0.014550
NUPR1	-0.014448
RRAS2	-0.014414
UNC13B	-0.014218
KRT12	-0.014192
CRTAC1	-0.014077
MLIP	-0.013712
GARNL3	-0.013303
HLA-DQA1	-0.013264
HS3ST2	-0.013243
IL22RA1	-0.013163
MEF2C	-0.013079
SIDT1	-0.012992
GNG4	-0.012960
EID1	-0.012814
GCA	-0.012684
PDZRN3	-0.012508
DKK3	-0.012445
OMP	-0.012408
OTX2	-0.012382
CPNE9	-0.012297
CADPS2	-0.012202
EXT1	-0.012195
LGALS1	-0.012166
BMP3	-0.012132
PDE1A	-0.011936
PLIN4	-0.011683
CHGB	-0.011454
UBE2QL1	-0.011439
LYPD6B	-0.011412
PTPRT	-0.011302
CCL17	-0.011270
R3HDM2	-0.011174
CBLN2	-0.011109
COL24A1	-0.011006
FAM131A	-0.010985
CALML4	-0.010974
SOX18	-0.010903
OVOL2	-0.010887
SATB1	-0.010810
HLA-DQB1	-0.010809
HS3ST1	-0.010784
FAAH	-0.010778
PAMR1	-0.010681
KCNC4	-0.010610
STARD8	-0.010607
TUBA8	-0.010541
FXYD7	-0.010523
DOC2A	-0.010512
PRSS35	-0.010482
TPPP	-0.010462
IGF2	-0.010462
SOX5	-0.010434
TRIM54	-0.010353
ALOX12B	-0.010351
DLGAP1	-0.010236
RSPO2	-0.010157
RASGEF1C	-0.010099
COL5A1	-0.010067
TRHDE	-0.010040
SV2B	-0.009971
SOBP	-0.009866
ARNT2	-0.009846
MKX	-0.009835
CPNE4	-0.009763
B4GALT4	-0.009638
COL8A1	-0.009526
GPR22	-0.009521
HAPLN4	-0.009502
PDLIM1	-0.009457
CHRD	-0.009381
OTOP2	-0.009367
BTBD10	-0.009300
VSNL1	-0.009205
MSX1	-0.009197
SERINC2	-0.009194
CPLX2	-0.009074
ID2	-0.009073
ADAMTSL2	-0.009055
CD6	-0.009036
TMEM108	-0.008968
KCNV1	-0.008957
LDB2	-0.008922
GOPC	-0.008917
PTPRU	-0.008848
KLHL40	-0.008846
GOLGA7B	-0.008806
RNF115	-0.008769
DIO2	-0.008655
ALDH3A1	-0.008593
CACNA2D1	-0.008478
SLC39A10	-0.008475
VPS26B	-0.008464
E2F1	-0.008385
KHDRBS3	-0.008309
SERPING1	-0.008302
C2orf82	-0.008258
SLC6A7	-0.008233
SCHIP1	-0.008224
CA10	-0.008093
CHMP4B	-0.008067
SLC23A3	-0.007993
KCNMB4	-0.007983
MICU3	-0.007941
LRFN2	-0.007936
AEBP1	-0.007920
THBD	-0.007878
OR5AC2	-0.007859
NFIX	-0.007801
APBA2	-0.007684
PNMT	-0.007676
COL4A1	-0.007609
STEAP1	-0.007582
BOK	-0.007578
CYFIP2	-0.007574
ASPG	-0.007548
TSPAN17	-0.007544
FXYD5	-0.007541
PLS3	-0.007528
RAD51AP2	-0.007526
AKR1C3	-0.007430
PGM2L1	-0.007412
PDIA4	-0.007308
PAK1	-0.007280
KLK6	-0.007252
SCUBE1	-0.007248
OLFM2	-0.007212
CA4	-0.007168
HK1	-0.007147
PRKAR1B	-0.007141
PRKCG	-0.007118
TUBB4A	-0.007117
GPX2	-0.007111
TMEM125	-0.007095
SLC6A3	-0.007093
NTNG2	-0.007081
RDH5	-0.007041
GNG2	-0.007041
TFAP2D	-0.006992
CAPN6	-0.006980
FBXW7	-0.006976
LTK	-0.006971
SCGN	-0.006939
PCOLCE	-0.006908
CELSR1	-0.006907
CCND1	-0.006904
PLEKHA2	-0.006892
LGR5	-0.006844
CDYL2	-0.006821
SOCS3	-0.006815
CIRBP	-0.006796
CDKN1A	-0.006787
TEKT1	-0.006772
PPM1E	-0.006741
RSU1	-0.006726
CORO1A	-0.006712
NEUROD1	-0.006708
SPRN	-0.006705
TMEM145	-0.006690
DHCR24	-0.006652
KIAA1549L	-0.006627
FGF3	-0.006624
WISP1	-0.006623
PCP2	-0.006606
C6orf222	-0.006590
LLGL2	-0.006560
KLHL14	-0.006539
PRICKLE1	-0.006535
SHISA4	-0.006531
POC1A	-0.006530
C1orf115	-0.006524
C6orf15	-0.006485
TCF19	-0.006485
BDNF	-0.006472
MAPRE3	-0.006472
COX7A1	-0.006433
ZBTB7A	-0.006415
TMEM184C	-0.006390
EXTL1	-0.006363
CHST8	-0.006352
TNR	-0.006350
FGF5	-0.006346
AK5	-0.006341
PHOSPHO1	-0.006329
OVOS2	-0.006306