!direction	-1
!num_genes	250
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Curcumin
!smiles	COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
!pubchem_cid	969516
!cell_type	U937 cell line (monocyte)
!organism	human
!end_metadata
HSPA1A	-0.228763
BCL2A1	-0.123016
HERPUD1	-0.112492
ATF4	-0.109028
EEF1B2	-0.093378
PLIN2	-0.084795
HMOX1	-0.084228
MMP7	-0.082186
CXCR4	-0.078973
DNAJB9	-0.078970
HSPE1	-0.075809
RGS2	-0.073215
CTSH	-0.070732
HSP90AA1	-0.070222
DNAJB1	-0.069602
SRXN1	-0.067938
LASP1	-0.066374
HSP90AB1	-0.065582
EGR2	-0.064212
RPS8	-0.063953
HSPA8	-0.063755
ATF3	-0.060001
CKS2	-0.059709
HSPB1	-0.057833
CITED2	-0.057633
SSR2	-0.056934
DNAJA1	-0.054682
TM4SF1	-0.053976
HSPH1	-0.053155
FABP5	-0.052307
TMEM123	-0.050992
JUN	-0.049733
CCL7	-0.049691
IER3	-0.049616
HSPA5	-0.049604
ABHD3	-0.049127
MT2A	-0.048051
ARPC1B	-0.047898
SRP9	-0.047825
PTGES3	-0.045871
DUSP5	-0.045614
HMGN2	-0.045424
CD83	-0.043836
DEDD2	-0.043558
TMEM258	-0.043146
TDP2	-0.042675
NSMAF	-0.041541
RPL36	-0.041517
LINC00657	-0.041395
BAG3	-0.039613
SEC61B	-0.039438
ZFAND2A	-0.039381
DEK	-0.039092
FLNA	-0.039017
MT1X	-0.038777
SLC38A2	-0.038248
MAFF	-0.038078
LITAF	-0.037753
LRIF1	-0.037705
ACSL1	-0.037613
IFITM2	-0.036415
FNIP2	-0.036302
PIM1	-0.036260
LSM7	-0.036139
AQP9	-0.035424
CHIC2	-0.035314
PMAIP1	-0.034832
MT1E	-0.034104
DUSP1	-0.034057
RPS25	-0.033792
PPP1R15A	-0.033647
HNRNPK	-0.033619
MGAT1	-0.033460
CHSY1	-0.033351
CNBP	-0.032489
SNRPB2	-0.032269
DBI	-0.032245
FGR	-0.032140
MYL12A	-0.032071
STARD3NL	-0.031891
TRIB3	-0.031848
PLEK	-0.031773
HK2	-0.031465
MANF	-0.031339
VIMP	-0.030923
C19orf10	-0.030870
PRDX4	-0.030434
UBB	-0.030173
WDR82	-0.029780
THBD	-0.029775
ISG15	-0.029354
AHSA1	-0.029138
SLC7A11	-0.029097
ATP6V1G1	-0.029090
SLC17A5	-0.029083
SEP15	-0.029065
RPL26	-0.028716
RAB1A	-0.028059
IDH1	-0.027883
H1F0	-0.027807
P4HB	-0.027589
HIST1H2BK	-0.027537
MAPK6	-0.027533
MTHFD2	-0.026915
IER5	-0.026480
MNDA	-0.026370
CD164	-0.026277
UBE2L6	-0.026258
COA6	-0.026201
SELK	-0.026158
OSBPL8	-0.025982
RPS26	-0.025865
OSTC	-0.025791
TCEB1	-0.025760
TBCA	-0.025438
TGFBR1	-0.025173
LAMTOR5	-0.024891
MT1H	-0.024883
TDO2	-0.024811
SLBP	-0.024720
CAPNS1	-0.024539
SRP19	-0.024458
DTX3L	-0.024453
DPM1	-0.024386
DENND5A	-0.024326
PPP1R15B	-0.024321
PSMC6	-0.024298
RPL11	-0.024205
SERTAD2	-0.024136
NDUFAB1	-0.024094
CCR1	-0.024042
CHMP5	-0.024008
ATP5B	-0.023893
TTYH3	-0.023661
SMAP1	-0.023486
CSGALNACT2	-0.023362
EIF2A	-0.023349
DUSP6	-0.023312
HSPA13	-0.023283
CCT3	-0.023282
CYTIP	-0.023271
CTSS	-0.023190
FAU	-0.023169
ARPC3	-0.023135
CKS1B	-0.023037
EEF2	-0.023009
NDEL1	-0.022964
PPIB	-0.022873
ARF4	-0.022753
NME1	-0.022733
TNFSF15	-0.022698
HSPA6	-0.022581
NPC1	-0.022509
EIF3E	-0.022325
OLIG1	-0.022167
PSMB8	-0.022147
GORASP2	-0.022105
CEBPB	-0.022104
YRDC	-0.022020
UBE2Q2	-0.021993
DUT	-0.021938
RPS13	-0.021875
PCNA	-0.021681
FKBP1A	-0.021609
B4GALT5	-0.021433
DLD	-0.021396
CBX3	-0.021205
LBR	-0.021134
HIST1H2AC	-0.021099
YWHAG	-0.021091
MID1IP1	-0.020913
RAN	-0.020873
CLEC5A	-0.020799
TXNRD1	-0.020765
GSR	-0.020754
COX7A2	-0.020713
RARS	-0.020685
RNF4	-0.020649
KLF6	-0.020574
MX2	-0.020536
MYADM	-0.020047
TUBB3	-0.020021
SLC25A6	-0.020008
TOMM20	-0.020003
ITGA6	-0.019964
IARS	-0.019710
GPX4	-0.019658
SNRPB	-0.019465
SARAF	-0.019421
EIF1	-0.019400
RNF149	-0.019373
GABARAPL2	-0.019246
IFI6	-0.019173
PARP4	-0.019158
BTG1	-0.019152
CXCL3	-0.019149
TRMT5	-0.018961
AIDA	-0.018937
PPP4C	-0.018916
RRM2	-0.018815
HSPD1	-0.018809
CXCL2	-0.018802
MOB4	-0.018766
GCLM	-0.018705
MRPL18	-0.018682
NAMPT	-0.018663
IFITM1	-0.018646
XPOT	-0.018590
NPTN	-0.018541
PSMA6	-0.018527
CACYBP	-0.018518
DYNC1I2	-0.018464
TUBB4B	-0.018445
ADO	-0.018295
ZNF267	-0.018293
RNH1	-0.018250
METTL9	-0.018143
NFE4	-0.018076
NHP2	-0.017988
MT1HL1	-0.017876
SLC1A5	-0.017812
UBL5	-0.017734
BRI3	-0.017733
MGAT2	-0.017664
ZC3HAV1	-0.017580
SNRPG	-0.017500
MS4A4A	-0.017444
TOP2B	-0.017280
ENOPH1	-0.017277
DNAJB11	-0.017264
CNEP1R1	-0.017154
PNRC1	-0.017150
TTC19	-0.017046
GOLGA4	-0.016961
ITPA	-0.016882
PPP1R18	-0.016877
FCAR	-0.016875
GFPT1	-0.016870
MIS12	-0.016765
KPNA2	-0.016670
PYGL	-0.016571
EIF1B	-0.016550
NACAP1	-0.016511
GCLC	-0.016484
PSMB9	-0.016470
TMED2	-0.016376
EFR3A	-0.016259
OXSR1	-0.016204
HSP90B1	-0.016065
IFNGR2	-0.016052