!direction	-1
!num_genes	252
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	Metformin
!smiles	CN(C)C(=N)N=C(N)N
!drugbank_id	DB00331
!pubchem_cid	4091
!cell_type	liver
!organism	mouse
!end_metadata
INMT	-0.174434
CYP2F1	-0.130843
PHYH	-0.124357
SCD	-0.093576
HPD	-0.092332
CES1	-0.090407
CA3	-0.084228
SLC27A2	-0.077724
GNMT	-0.076537
HERPUD1	-0.076004
GSTP1	-0.073359
EPHX2	-0.073213
GSTA5	-0.071979
RETSAT	-0.071461
PIGR	-0.070785
SLC27A5	-0.068288
AADAC	-0.066394
TAT	-0.063699
PON1	-0.060343
HSD11B1	-0.059591
TMEM205	-0.059257
UGT2B7	-0.057417
SERPINA6	-0.056786
CYP4A22	-0.055849
C8G	-0.054523
TTC36	-0.054176
NDUFA13	-0.053875
LPIN1	-0.053579
EPHX1	-0.052610
AZGP1	-0.052315
ACAD11	-0.052271
CYP1A2	-0.050057
SLC10A1	-0.049825
SERPINF1	-0.049074
ALAS1	-0.047922
APOA2	-0.046298
AKR1C4	-0.046216
GHR	-0.044576
ERRFI1	-0.044554
MBL2	-0.044507
OAT	-0.042100
C8A	-0.041151
UPB1	-0.040489
SORD	-0.040004
CDO1	-0.039833
CYP2C8	-0.039416
ECH1	-0.039385
NUDT7	-0.039290
UPP2	-0.038533
HEBP1	-0.037255
REEP6	-0.037140
BNIP3	-0.036872
CCRN4L	-0.036689
AHCY	-0.036451
EIF4A2	-0.036312
NDRG2	-0.035508
GLS2	-0.035308
VKORC1	-0.035179
UGT2B17	-0.035023
GABARAPL1	-0.035000
APOH	-0.034738
CYP4V2	-0.034317
PPP1R3G	-0.034165
KLF15	-0.033774
ACAA2	-0.033666
ACAT1	-0.033633
PLG	-0.033458
UGT2A3	-0.033369
FXYD1	-0.033088
PROC	-0.032957
ETNPPL	-0.032787
ACADM	-0.032529
HAAO	-0.032362
PGRMC1	-0.032261
GSTM5	-0.032059
KLKB1	-0.031836
LIPC	-0.031685
HRSP12	-0.031262
SLCO1B3	-0.031155
UGT2B28	-0.030884
RGN	-0.030099
CYP8B1	-0.029508
DUSP1	-0.029474
PYGL	-0.029348
MARC1	-0.029097
CFHR1	-0.029096
G6PC	-0.028701
MARC2	-0.028612
FAH	-0.028589
ALB	-0.028494
HSD17B6	-0.028484
PPARA	-0.028088
TTPA	-0.027574
DBP	-0.027524
LYZ	-0.027233
TMBIM6	-0.026848
AFM	-0.026766
PHLDA1	-0.026157
SLC37A4	-0.026124
ALDH3A2	-0.026104
NDUFA4	-0.025866
FAU	-0.025762
PIPOX	-0.025667
ACSM1	-0.025169
MAOB	-0.025159
SDHB	-0.025146
LCAT	-0.025142
CSAD	-0.025088
CISD1	-0.025008
FDX1	-0.024932
CMBL	-0.024876
PIM3	-0.024564
CEBPA	-0.024534
ACTG1	-0.024453
ABCC3	-0.024378
PXMP2	-0.024301
RGS16	-0.024231
CTH	-0.024153
ECI1	-0.024147
ACSL1	-0.024087
BLVRB	-0.024067
OTC	-0.024037
GSTA3	-0.023891
THRSP	-0.023666
SLC2A2	-0.023395
HPN	-0.023310
UGT3A1	-0.022933
ISCU	-0.022910
ABHD14B	-0.022833
PEX11A	-0.022610
SARDH	-0.022519
PBLD	-0.022509
SUCLG1	-0.022463
GLO1	-0.022345
PPAP2B	-0.022334
CEBPB	-0.022305
ADH4	-0.022149
PSMA4	-0.022007
SEC14L2	-0.021751
GPLD1	-0.021497
HAGH	-0.021487
RBP4	-0.021476
ETFA	-0.021416
CYP4F12	-0.021280
CTSS	-0.020952
COX4I1	-0.020948
AMY2A	-0.020840
ALDH1L1	-0.020632
GPCPD1	-0.020062
AGXT	-0.020013
SAA2-SAA4	-0.019952
APOE	-0.019847
DPYS	-0.019818
SLC38A3	-0.019674
ALDH9A1	-0.019525
HADH	-0.019414
ITM2B	-0.019298
ANGPTL3	-0.019296
ABCD3	-0.019034
AOX1	-0.018907
CYP27A1	-0.018888
GSTZ1	-0.018845
TMPRSS6	-0.018473
ATP5A1	-0.018136
CCBL2	-0.018115
BHLHE40	-0.017892
KHK	-0.017651
ABCC2	-0.017547
FTCD	-0.017353
GLUL	-0.017295
C6	-0.017197
GPNMB	-0.017190
F13B	-0.017118
LPL	-0.017096
GAMT	-0.016921
ARL6IP1	-0.016708
PEX7	-0.016508
CREG1	-0.016477
TTC39C	-0.016376
CYB5A	-0.016355
ITIH1	-0.016354
GCHFR	-0.016296
NIT2	-0.016287
ECHS1	-0.016221
UQCR11	-0.016160
RAB30	-0.016111
ADH1C	-0.016045
AMACR	-0.015875
ACOX1	-0.015826
HIBADH	-0.015807
CHPT1	-0.015801
DCXR	-0.015766
AK2	-0.015709
CA2	-0.015692
GCH1	-0.015628
TYROBP	-0.015593
ABAT	-0.015566
CCS	-0.015504
SERPINC1	-0.015413
PTTG1	-0.015279
MMP12	-0.015273
DHRS4	-0.015122
STBD1	-0.015118
RPL8	-0.015075
GJB1	-0.015069
NR1I3	-0.015069
NDUFB9	-0.015053
G0S2	-0.015017
HAO1	-0.015009
CAT	-0.014958
ALDH7A1	-0.014840
ETFB	-0.014690
GSTK1	-0.014644
CD74	-0.014605
DGAT2	-0.014546
SLC47A1	-0.014431
CYP4F8	-0.014404
METTL7A	-0.014360
NDUFA6	-0.014220
HSD3B1	-0.014219
COL18A1	-0.014133
NDUFV3	-0.014074
UQCRC1	-0.013944
SLC17A2	-0.013919
BRI3	-0.013733
HAL	-0.013609
NFKBIA	-0.013480
HSD17B10	-0.013463
CHDH	-0.013461
CYP7B1	-0.013312
SLC7A2	-0.013094
PSAP	-0.013088
HSD17B2	-0.013088
SELENBP1	-0.013053
MLXIPL	-0.012992
SEMA4G	-0.012888
PPP1R3B	-0.012687
IDH1	-0.012661
C11orf54	-0.012608
HINT2	-0.012587
ATRAID	-0.012574
CLEC7A	-0.012529
GYS2	-0.012488
AKR7A2	-0.012452
ASPG	-0.012324
CYP7A1	-0.012246
COQ10B	-0.012237
DHDH	-0.012231
NIPSNAP1	-0.012150
ALDH8A1	-0.012142
CST3	-0.012133
TSC22D1	-0.012113