!direction	-1
!num_genes	332
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!drug_name	orotic acid
!smiles	C1=C(NC(=O)NC1=O)C(=O)O
!pubchem_cid	967
!cell_type	Livers ( from outbred Wistars - fed a diet with 1% orotic acid) - 14 Day
!organism	rat
!end_metadata
VTN	-0.212745
RPS29	-0.167758
APOA2	-0.166874
RPL23	-0.160288
APOA1	-0.128968
RPS16	-0.122784
FGB	-0.118351
FTH1	-0.117740
PCK1	-0.109600
CDO1	-0.098971
ACAA2	-0.095773
CFB	-0.093816
RBP1	-0.086980
TPT1	-0.086684
SLC27A2	-0.084237
PAH	-0.080888
BAAT	-0.079421
INSIG1	-0.078672
AFM	-0.078476
SEPP1	-0.078101
ITIH3	-0.076510
RPS12	-0.075734
PLIN2	-0.073024
APOH	-0.071291
ALDH2	-0.070466
RPS13	-0.070403
PROS1	-0.069702
SERPING1	-0.069027
RPL31	-0.068149
SPP2	-0.067781
ATP5B	-0.067465
RPL12	-0.065899
KHK	-0.064637
SERPIND1	-0.064567
ARG1	-0.064387
LDHA	-0.063713
RPS27A	-0.062293
F2	-0.061178
GLUD1	-0.060850
TMEM205	-0.060507
HPX	-0.060351
B2M	-0.059966
APOM	-0.058930
ALDOB	-0.058836
RPL18A	-0.057376
CYB5A	-0.056756
METTL7B	-0.056736
PON1	-0.055930
RPL18	-0.054574
PGRMC1	-0.052441
RPL19	-0.052267
HSD11B1	-0.051893
CSAD	-0.051387
SLC10A1	-0.051199
AMBP	-0.051111
TARS	-0.050709
RPS21	-0.050004
ST6GAL1	-0.049591
HRSP12	-0.049211
DBI	-0.048541
RPL9	-0.047818
ERRFI1	-0.047184
TUBA1C	-0.047060
MIF	-0.043881
PTTG1IP	-0.043475
GHR	-0.043333
RPS4Y1	-0.042721
PROC	-0.042408
ACTG1	-0.042364
G6PC	-0.042259
C8B	-0.042089
ACLY	-0.040998
G0S2	-0.040533
RPSA	-0.040118
CPS1	-0.040061
RPL15	-0.040034
RPL4	-0.039983
BSG	-0.039253
BDH1	-0.039185
RPL28	-0.039158
SULT2A1	-0.038997
KYNU	-0.038936
HSP90AB1	-0.038584
TDO2	-0.037683
HAGH	-0.036942
HSD17B13	-0.035283
RPS11	-0.034680
APOC4	-0.034593
RPL26	-0.034538
GSTM5	-0.034201
SCD	-0.033948
RPS23	-0.033548
APCS	-0.033251
RPL24	-0.033134
C9	-0.032107
CTSC	-0.031985
TTPA	-0.031614
RPL11	-0.030977
RPL13A	-0.030856
RPL8	-0.030384
CAT	-0.029993
RPL5	-0.029962
RPS6	-0.029442
LIPC	-0.029403
PGK1	-0.029282
CST3	-0.028618
IGFALS	-0.028317
RPS9	-0.028223
RPS26	-0.028007
PSAP	-0.027852
ADK	-0.027647
RPS5	-0.027606
RGN	-0.027391
HMGCS2	-0.027359
APOA4	-0.027086
APOB	-0.026984
MST1	-0.026900
KLKB1	-0.026684
RPS15A	-0.026577
TECR	-0.026488
UGT2B17	-0.026187
SERPINA10	-0.026142
ALDH6A1	-0.026125
RPS7	-0.026111
ATP5C1	-0.025912
SULT1B1	-0.025789
RPS15	-0.025728
CTSS	-0.025648
DDC	-0.025478
PRDX1	-0.025014
SQLE	-0.024704
MTCH2	-0.024469
TTC36	-0.024466
MORF4L2	-0.024085
AK4	-0.024078
SDC4	-0.024071
SPINT2	-0.023980
RPL22	-0.023949
AGT	-0.023845
OAZ1	-0.023776
DPYS	-0.023679
HAAO	-0.023648
RPL17	-0.023602
NDUFA8	-0.023487
CPQ	-0.023347
CES1	-0.023312
OTC	-0.023251
ALAD	-0.023242
FTL	-0.023228
NR0B2	-0.022711
FN1	-0.022613
NUP88	-0.022357
SEC61B	-0.022032
DIO1	-0.022017
HNRNPK	-0.021622
IGF1	-0.021613
GNE	-0.021466
CTSB	-0.021176
MAOB	-0.020862
EPHX1	-0.020638
CD63	-0.020549
EIF5	-0.020476
SLC41A2	-0.020470
CTH	-0.020225
LAMP2	-0.020175
RPS8	-0.020055
DDX3X	-0.020038
FAU	-0.019805
UBR5	-0.019295
CP	-0.018986
RPL35	-0.018839
MPC1	-0.018649
RPL30	-0.018400
PAPSS2	-0.018272
CYP1A2	-0.018254
SLC6A13	-0.018248
MAN2B1	-0.018231
CPT2	-0.018125
MDH2	-0.018053
TALDO1	-0.017918
PPP1CA	-0.017907
RPS17	-0.017737
ETNK2	-0.017611
ENPP3	-0.017379
AUH	-0.017292
COX1	-0.017018
UGT2B28	-0.017017
ACADM	-0.016952
C11orf73	-0.016949
AGTR1	-0.016942
GSTA5	-0.016938
RPLP2	-0.016931
HPN	-0.016790
SCLY	-0.016765
RPS10	-0.016684
F9	-0.016643
FAAH	-0.016397
ACADL	-0.016363
XDH	-0.016180
ANAPC5	-0.015852
PXMP2	-0.015730
AADAT	-0.015695
RPS3	-0.015377
ITIH4	-0.015191
EEF1G	-0.015147
DDT	-0.015146
DDRGK1	-0.015015
DAO	-0.014824
PDAP1	-0.014816
NDUFB8	-0.014797
AGXT2	-0.014763
TMEM47	-0.014741
HSD3B7	-0.014704
MARC2	-0.014660
TMED2	-0.014499
C1QB	-0.014404
RPL27	-0.014333
IDH1	-0.014182
AZGP1	-0.014127
AMY2B	-0.014119
SLC2A2	-0.014096
ETFA	-0.013911
MAOA	-0.013478
HIBADH	-0.013423
COX7A2	-0.013406
IGFBP1	-0.013341
FGG	-0.013338
PPIA	-0.013180
NDUFB3	-0.013171
CTDSP1	-0.013165
SLC26A1	-0.013126
CLEC4F	-0.013068
HSPA8	-0.013063
YWHAB	-0.012993
SERPINA6	-0.012830
NR1H4	-0.012776
HACL1	-0.012729
ENO1	-0.012684
INHBE	-0.012604
RPN2	-0.012398
LITAF	-0.012212
COX5A	-0.012189
RPL10A	-0.012155
SLC25A3	-0.012131
EIF3B	-0.012097
FABP6	-0.012079
HSP90AA1	-0.012010
CA3	-0.011916
RPP21	-0.011894
GDA	-0.011882
SDCBP	-0.011860
TMEM59	-0.011792
DLST	-0.011742
FUCA1	-0.011741
PLG	-0.011551
NPM1	-0.011406
FAH	-0.011260
ZFAND6	-0.011216
HNRNPA2B1	-0.011177
PTGR1	-0.011056
FGA	-0.010991
MBL2	-0.010939
PTPLAD1	-0.010870
ATP5A1	-0.010846
TUBA1B	-0.010559
DDAH1	-0.010544
EIF4A2	-0.010515
GCKR	-0.010421
CXXC5	-0.010273
MAP3K1	-0.010267
ARF4	-0.010142
ATRN	-0.010112
H2AFZ	-0.010086
NPHP1	-0.010078
HSD17B12	-0.010036
DHFR	-0.010020
COPZ1	-0.010015
PIGR	-0.009997
CDC37	-0.009939
SLCO2A1	-0.009892
SUCLG1	-0.009870
PEMT	-0.009691
NR1H3	-0.009634
FAM160B1	-0.009631
RPL27A	-0.009606
CTBS	-0.009574
AVPR1A	-0.009528
GYS2	-0.009471
SIGMAR1	-0.009436
CPD	-0.009136
TAT	-0.009090
NDUFC2	-0.008998
CABIN1	-0.008910
SLC22A1	-0.008903
RPS25	-0.008797
FABP7	-0.008760
GNG5	-0.008742
AES	-0.008603
FCGRT	-0.008514
CTSH	-0.008423
PTPRF	-0.008423
CLUH	-0.008421
ALDH1L1	-0.008395
NME2	-0.008343
GABARAP	-0.008283
SLC16A1	-0.008279
YWHAH	-0.008234
TKT	-0.008220
CLTB	-0.008199
RABGGTB	-0.008170
BCKDHB	-0.008169
CEBPB	-0.008164
UNC50	-0.008157
AIFM1	-0.008073
GDI2	-0.008066
GTF2A2	-0.008041
GNB2L1	-0.008013
LAMTOR1	-0.008002
RPL21	-0.007946
NDUFV3	-0.007898
GABARAPL2	-0.007840
PPIF	-0.007820
COPB2	-0.007812
HSD17B10	-0.007796
ADIPOR2	-0.007772
NCKAP1	-0.007762
PSMC1	-0.007729
APLP2	-0.007728
INS	-0.007684
SQSTM1	-0.007659
CNPY2	-0.007635
BTG2	-0.007611