!direction	-1
!num_genes	297
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Heroin
!smiles	CC(=O)OC1C=CC2C3CC4=C5C2(C1OC5=C(C=C4)OC(=O)C)CCN3C
!drugbank_id	DB01452
!pubchem_cid	5462328
!cell_type	striatum, day 12 treatment
!organism	mouse
!end_metadata
OXT	-0.125764
FOS	-0.124200
PMCH	-0.115313
S100A5	-0.112791
HCRT	-0.111901
EGR2	-0.108672
SLC13A4	-0.102224
ARC	-0.097633
ND6	-0.094751
SLC6A13	-0.080378
STMN1	-0.066779
R3HDM2	-0.060771
RXRG	-0.060548
ND4L	-0.060532
KIAA1462	-0.060141
HLA-DQA1	-0.057254
OMP	-0.052848
AEBP1	-0.052635
NR4A2	-0.052422
NDRG4	-0.050640
MXI1	-0.049221
PTGDS	-0.048937
SLC6A12	-0.048560
ST13	-0.048118
THBD	-0.047315
CRYAB	-0.045949
SPARCL1	-0.045487
VPS26B	-0.045163
HLA-DRB5	-0.044056
SERPING1	-0.043677
CALB2	-0.043483
GLUL	-0.042780
FAM180A	-0.041598
ARNTL	-0.041136
CHMP5	-0.040499
PAIP2	-0.038935
PCMTD2	-0.038074
VAPA	-0.037664
IGF2	-0.037341
GPR17	-0.035936
TRIM59	-0.035842
IDO1	-0.035300
CRYBG3	-0.035102
CD74	-0.034695
NTN5	-0.034503
HLA-DQB1	-0.034206
ARHGAP33	-0.033318
HSPE1	-0.033266
DOK3	-0.033004
EFNB2	-0.032632
AGPAT3	-0.032231
VHL	-0.032221
EGR4	-0.031493
WNT2	-0.030595
ARPC2	-0.030335
PGRMC1	-0.030326
TRRAP	-0.030318
TOMM70A	-0.029855
SLC22A6	-0.029796
ERBB2IP	-0.029787
S100B	-0.029358
DCN	-0.028961
RASGEF1A	-0.028743
CYFIP2	-0.028520
GJB2	-0.028116
TPPP	-0.027947
MMP23B	-0.027856
CLSPN	-0.027726
SDHD	-0.027451
PCP4	-0.027006
OGN	-0.027000
RPL18A	-0.026911
FAM171A1	-0.026885
TMEM178A	-0.026744
DUSP1	-0.026193
BGN	-0.026078
ADAM9	-0.025981
MAP2K1	-0.025958
TUBA1A	-0.025608
HSPA8	-0.024468
SLAIN1	-0.024243
SNAPC1	-0.024181
OTUD6B	-0.024073
GRAMD4	-0.023794
TRA2A	-0.023705
C8orf46	-0.023480
SLC35D3	-0.023459
ACADSB	-0.023277
SNX3	-0.023246
GNG11	-0.023237
NUPR1	-0.023061
TJP1	-0.022604
LPAR1	-0.022518
RGS9	-0.022368
TBC1D19	-0.022337
PRELP	-0.022285
EMP1	-0.022191
ITIH2	-0.021933
GPR88	-0.021849
P4HA1	-0.021456
SELK	-0.021454
SYNDIG1L	-0.021424
MAP1LC3B	-0.021417
PCDH20	-0.021251
IDH3A	-0.021212
ARHGEF26	-0.021028
RGMA	-0.020935
CHORDC1	-0.020879
SLC47A1	-0.020719
BHLHE22	-0.020678
RRAS2	-0.020567
CCNG2	-0.020530
C1QL2	-0.020479
FFAR3	-0.020323
GPR6	-0.020263
ST8SIA2	-0.020262
ST8SIA3	-0.020218
CACNG4	-0.019968
C15orf61	-0.019835
PDCD5	-0.019737
RANBP3L	-0.019717
EGR1	-0.019589
PLA2G7	-0.019574
NKX2-1	-0.019419
TRHR	-0.019361
DUSP11	-0.019359
PMPCB	-0.019305
CD93	-0.019279
PRPSAP2	-0.019071
FXYD5	-0.019054
SPHK1	-0.018941
IGSF1	-0.018930
RBM14	-0.018927
PTPRA	-0.018836
ISL1	-0.018813
MYL4	-0.018792
OTOF	-0.018677
CRYZL1	-0.018663
ABLIM2	-0.018661
GJB1	-0.018655
PTPN1	-0.018636
DDIT4L	-0.018584
ID4	-0.018542
RASSF8	-0.018538
ATP5A1	-0.018531
NDUFA5	-0.018447
SPTSSA	-0.018415
OMD	-0.018407
NSUN7	-0.018347
GBX2	-0.018297
DND1	-0.018221
PLTP	-0.018189
LIN7C	-0.018145
ETV5	-0.018069
PCOLCE	-0.018029
FOSB	-0.018025
CACNG3	-0.017909
GCLC	-0.017854
LHFPL2	-0.017825
HSPB1	-0.017722
PSMD14	-0.017651
NDUFB9	-0.017628
NPAS4	-0.017581
LHFPL5	-0.017542
RER1	-0.017394
IGFBP2	-0.017318
IRGM	-0.017296
DZANK1	-0.017144
CDHR1	-0.017094
HTR1D	-0.017083
GPM6A	-0.017054
TXNDC12	-0.017017
ME1	-0.016992
RYR1	-0.016968
PAM16	-0.016947
TNFRSF25	-0.016893
ITGA10	-0.016890
FYCO1	-0.016850
NDUFAF5	-0.016821
FOXC1	-0.016791
S100A10	-0.016706
KRT14	-0.016645
MEIS2	-0.016619
NEU2	-0.016617
RARB	-0.016557
PICALM	-0.016528
ZNF442	-0.016471
HTT	-0.016445
NAP1L5	-0.016346
HSP90B1	-0.016288
KCTD12	-0.016260
CAPRIN1	-0.016223
ARHGEF19	-0.016111
PTGES3	-0.016051
EMP2	-0.016035
PLEKHA3	-0.015993
OR1N2	-0.015978
LRRTM3	-0.015942
SERPINH1	-0.015927
COX2	-0.015922
INSC	-0.015897
C17orf70	-0.015883
DRD2	-0.015849
SLC20A1	-0.015748
IGFBP5	-0.015736
FMOD	-0.015727
IST1	-0.015714
RPE65	-0.015705
FOXG1	-0.015656
SFR1	-0.015589
CLDN5	-0.015556
BMS1	-0.015555
ABHD17C	-0.015460
FTL	-0.015437
PHOX2A	-0.015356
BCAS2	-0.015314
NAP1L3	-0.015264
ATP6	-0.015245
CFP	-0.015208
KLF2	-0.015107
PF4	-0.015096
AVP	-0.015096
VIT	-0.015076
NRP1	-0.015030
EVL	-0.014984
USP28	-0.014981
AK4	-0.014934
KPNB1	-0.014932
FKBP2	-0.014914
CCKBR	-0.014829
TPT1	-0.014728
PDLIM7	-0.014686
SLC23A2	-0.014630
HMHA1	-0.014604
RIC8B	-0.014597
HUWE1	-0.014585
FGFBP1	-0.014582
PHEX	-0.014544
PARP8	-0.014538
ZFP36L1	-0.014479
TMEM64	-0.014457
IFITM3	-0.014445
ZNF780A	-0.014435
OPN1LW	-0.014409
RGS10	-0.014370
OLFM3	-0.014367
IRX6	-0.014341
PDIA4	-0.014275
CCT5	-0.014261
YTHDF3	-0.014219
CCAR1	-0.014141
HPRT1	-0.014111
SPAST	-0.014066
ENO1	-0.014044
FAM216B	-0.014044
SLC52A3	-0.014043
NRN1	-0.014014
SOGA3	-0.013976
GADD45A	-0.013956
BDP1	-0.013949
ALCAM	-0.013904
CDK2AP2	-0.013877
FH	-0.013821
NETO2	-0.013811
SERPIND1	-0.013796
CYP1B1	-0.013738
STX1A	-0.013705
HIST1H2BJ	-0.013694
SLC39A10	-0.013691
CTSK	-0.013686
ADCY4	-0.013678
PDP1	-0.013648
TEK	-0.013637
GAB1	-0.013636
PIN4	-0.013609
ST8SIA4	-0.013605
CA4	-0.013604
MRO	-0.013595
OSBPL8	-0.013562
NKX6-2	-0.013543
ECI2	-0.013540
SUGCT	-0.013525
SDF2L1	-0.013519
EDNRB	-0.013499
CALR	-0.013447
SEPT8	-0.013431
AGO4	-0.013425
JOSD2	-0.013419
DDT	-0.013418
PRICKLE1	-0.013409
TXNRD1	-0.013395
GDI2	-0.013376
HSP90AA1	-0.013363
CA13	-0.013327
LEAP2	-0.013289
PDE10A	-0.013280
BCAP31	-0.013203