!direction	-1
!num_genes	431
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Fasudil
!smiles	C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3
!pubchem_cid	3547
!cell_type	Forebrain astrocytes - 6 Hours
!organism	mouse
!end_metadata
PES1	-0.053659
XBP1	-0.050422
TRMT61A	-0.050267
PLEKHG2	-0.049854
SNX33	-0.047608
PDLIM7	-0.046710
CHAC1	-0.045121
RIN1	-0.044698
ZNF655	-0.043757
TSC22D1	-0.043653
LDOC1L	-0.041821
TMEM185B	-0.041337
AP1M1	-0.041333
EXOC8	-0.041243
COMMD5	-0.041234
GPR123	-0.041156
IRF2BP1	-0.041155
JAGN1	-0.040927
ZFP41	-0.040541
DBP	-0.040486
HEXIM1	-0.040142
ORAI3	-0.039417
RIPK1	-0.039044
ORAI1	-0.038775
SOX21	-0.038732
C17orf70	-0.038355
FAM58A	-0.037623
PGPEP1	-0.037240
ZYX	-0.037232
WNT7A	-0.037210
ORAOV1	-0.036831
GLDN	-0.036762
N6AMT1	-0.036684
SH3BP5L	-0.036680
TULP4	-0.036623
MUM1	-0.036499
SUV420H2	-0.036423
POLRMT	-0.036177
ZC2HC1A	-0.036169
PRKD2	-0.036089
LENG9	-0.035694
DUS1L	-0.035663
ZNF436	-0.035603
TMEM177	-0.035453
ARMC6	-0.035238
NUDT18	-0.035135
SLX4	-0.035076
TRIP6	-0.035049
SPRED1	-0.035030
RNPEPL1	-0.034884
SSX2IP	-0.034688
WBP1L	-0.034664
SCG2	-0.034314
LBH	-0.034306
TMEM186	-0.034091
NUDT22	-0.034077
SSU72	-0.034013
FAM167A	-0.034001
SRM	-0.033945
LZTS2	-0.033660
RBM4B	-0.033550
FADD	-0.033505
SUCNR1	-0.033402
C14orf119	-0.033379
TPRN	-0.033270
RGMA	-0.033154
SMARCAD1	-0.032960
PKP2	-0.032958
NUPR1	-0.032890
C17orf80	-0.032620
SPSB2	-0.032607
PRR14	-0.032591
UACA	-0.032374
EXOSC1	-0.032310
ZFP30	-0.032110
OTX1	-0.031983
DNAJB12	-0.031978
ZNF672	-0.031972
DNAJC30	-0.031896
FAM53C	-0.031748
PTX3	-0.031673
MTAP	-0.031580
STARD5	-0.031534
FAM49A	-0.031526
PPP1R11	-0.031446
GSPT2	-0.031404
ALKBH7	-0.031355
BCL7A	-0.031321
SIN3A	-0.031231
DOK5	-0.031116
MED8	-0.031078
OVCA2	-0.031014
FPGS	-0.030964
SAP30L	-0.030919
BTBD11	-0.030864
LIMK2	-0.030803
RAB34	-0.030791
FZR1	-0.030725
ABCG4	-0.030561
KAT5	-0.030461
PCGF1	-0.030338
AP5S1	-0.030255
KCTD21	-0.030229
SLC4A1AP	-0.030206
SRXN1	-0.030003
ZDHHC12	-0.029852
MKNK2	-0.029687
CCDC101	-0.029673
ATMIN	-0.029555
NAE1	-0.029551
WIPF1	-0.029464
TNFRSF1A	-0.029312
CSRP2BP	-0.029306
CASKIN2	-0.029305
MRPS7	-0.029123
RABIF	-0.029107
ZFPM1	-0.029045
COA4	-0.028913
TMEM199	-0.028847
DPP3	-0.028838
GTF2H2	-0.028833
SLC22A23	-0.028824
ZFP90	-0.028772
PREB	-0.028746
BET1L	-0.028719
ADRA2A	-0.028718
HSPB1	-0.028684
DGKG	-0.028652
PUS7L	-0.028612
LYPLA2	-0.028605
SPHK1	-0.028572
IRGM	-0.028427
C14orf79	-0.028337
CPT2	-0.028281
NR2F1	-0.028125
TAB1	-0.028088
LRFN3	-0.028081
RCAN1	-0.028049
ARL11	-0.028048
METTL3	-0.027965
ABCF3	-0.027941
B3GALT6	-0.027912
RPUSD4	-0.027876
SLC39A13	-0.027734
FAM111A	-0.027697
PSMG2	-0.027673
EIF4EBP1	-0.027629
SLC38A2	-0.027592
AFTPH	-0.027532
NME6	-0.027520
ATP10A	-0.027412
AGAP1	-0.027404
MYD88	-0.027397
STK17B	-0.027378
ARHGAP23	-0.027370
GPR146	-0.027315
SNX21	-0.027301
OXLD1	-0.027239
BCS1L	-0.027234
STX5	-0.027218
VEZF1	-0.027216
HSPA2	-0.027168
ARFGAP1	-0.027159
RAD1	-0.027100
RELA	-0.027099
BCL6	-0.026985
PQLC1	-0.026932
RXRB	-0.026891
IRF9	-0.026864
CCDC181	-0.026853
LDB1	-0.026822
FAM53A	-0.026818
TBC1D13	-0.026730
FZD2	-0.026719
PARD6A	-0.026661
YEATS4	-0.026652
MSTO1	-0.026471
AGFG1	-0.026408
MRPS22	-0.026400
TFB1M	-0.026331
HSPA8	-0.026324
SYBU	-0.026300
CHRAC1	-0.026292
CSNK1G3	-0.026275
SLC25A45	-0.026272
PQLC2	-0.026249
GEMIN4	-0.026197
MAST2	-0.026150
ORC5	-0.026112
IARS	-0.026028
CC2D1A	-0.025980
ZMYND8	-0.025979
ARHGAP17	-0.025962
DHX32	-0.025953
RRP15	-0.025881
FJX1	-0.025784
PALD1	-0.025782
NUDT16L1	-0.025703
CREB3	-0.025701
FBXO28	-0.025700
EEF1E1	-0.025615
CCDC28B	-0.025607
TGFB3	-0.025553
MYO9B	-0.025552
SLC35C1	-0.025549
OTX2	-0.025530
NUPL2	-0.025522
TEFM	-0.025514
PCSK7	-0.025471
HYAL2	-0.025394
FBXO21	-0.025387
OSBPL2	-0.025303
SLC52A2	-0.025281
PPP1R26	-0.025205
CSNK1E	-0.025202
CSK	-0.025140
ZBTB22	-0.025086
MAP6	-0.025040
SYTL2	-0.025007
HPS6	-0.025005
POLR1E	-0.024992
CSNK2A2	-0.024981
DCUN1D4	-0.024927
C1orf50	-0.024848
KAT8	-0.024824
PLEKHM1	-0.024801
LSM8	-0.024764
CBX8	-0.024719
BTBD6	-0.024661
RNMTL1	-0.024631
DDIT3	-0.024624
MAT2A	-0.024619
HSF1	-0.024582
MAVS	-0.024561
EPT1	-0.024557
GTF2H4	-0.024523
GNAZ	-0.024477
NPRL2	-0.024459
STARD8	-0.024417
CCDC85B	-0.024394
NOL12	-0.024379
ZNF585A	-0.024363
AREL1	-0.024357
METTL1	-0.024345
PNPLA2	-0.024294
RAB11FIP5	-0.024237
MRM1	-0.024234
FAM203A	-0.024166
AIMP2	-0.024158
PRMT5	-0.024152
KIAA0226	-0.024133
VGF	-0.024041
ZFP3	-0.024012
IGF2BP2	-0.024001
PIGX	-0.023995
PANK4	-0.023936
PUS3	-0.023929
CTAGE5	-0.023924
PAQR7	-0.023919
CAMTA2	-0.023899
PDCD10	-0.023858
LSM10	-0.023790
EXO5	-0.023736
IRF3	-0.023715
TBL2	-0.023710
SKIDA1	-0.023659
RAB33B	-0.023657
SERTAD1	-0.023655
H6PD	-0.023634
BID	-0.023610
AARS	-0.023603
POLR3B	-0.023576
FAM107B	-0.023556
ANAPC4	-0.023552
RPAIN	-0.023499
TRIM28	-0.023499
SERTM1	-0.023463
ING4	-0.023443
TMEM261	-0.023418
SLC8B1	-0.023401
FUBP1	-0.023382
ELOVL1	-0.023374
SMAP2	-0.023248
DOLK	-0.023235
ARFGAP2	-0.023235
THAP11	-0.023220
WASF1	-0.023135
CFAP97	-0.023126
C2orf42	-0.023072
GAS8	-0.023066
SWAP70	-0.023057
DIS3L	-0.023035
RAB29	-0.023028
NT5M	-0.022988
FAM98A	-0.022985
RHOBTB2	-0.022953
NUDT7	-0.022914
NLK	-0.022908
GIPC1	-0.022900
MRPL12	-0.022894
TMEM53	-0.022874
NAV1	-0.022866
RARS2	-0.022861
ZFYVE21	-0.022812
RSAD1	-0.022795
SALL2	-0.022793
ZPR1	-0.022780
NDUFAF1	-0.022695
C17orf85	-0.022669
CTNS	-0.022668
SHH	-0.022658
FAM214B	-0.022646
AVPI1	-0.022616
GID8	-0.022596
CDKN2AIPNL	-0.022565
LY96	-0.022552
SLC26A6	-0.022532
ECD	-0.022524
UNC45A	-0.022499
MINA	-0.022479
IQGAP2	-0.022453
SIGMAR1	-0.022444
ENTPD4	-0.022432
NOP56	-0.022371
COX15	-0.022353
ARHGEF18	-0.022352
DTX2	-0.022343
INTS3	-0.022331
PPARGC1A	-0.022316
CDAN1	-0.022301
SF3A1	-0.022298
MTHFD2	-0.022259
DMAP1	-0.022181
EIF2B4	-0.022160
RUFY1	-0.022142
CDKN1A	-0.022140
PUF60	-0.022140
GPR85	-0.022069
TLK1	-0.022063
CCDC94	-0.022063
MTERF4	-0.022034
MLST8	-0.022023
GARS	-0.022014
DOK1	-0.021956
GBX2	-0.021938
SMIM12	-0.021898
MAPK14	-0.021885
TSEN2	-0.021875
AP4B1	-0.021875
BAG4	-0.021873
BLMH	-0.021821
LRRK1	-0.021819
SLAIN2	-0.021785
TJP2	-0.021784
COL4A2	-0.021779
WISP2	-0.021771
PIK3C3	-0.021771
GUCD1	-0.021748
VPS33B	-0.021728
LRRN3	-0.021725
C17orf62	-0.021704
SEPHS2	-0.021677
SUOX	-0.021665
SNX15	-0.021635
E2F6	-0.021633
SAC3D1	-0.021626
DDX27	-0.021620
SURF2	-0.021612
RAPGEF3	-0.021582
RPP25L	-0.021575
TMEM214	-0.021561
THAP7	-0.021560
GFER	-0.021478
TRIP10	-0.021421
SOX9	-0.021419
RCE1	-0.021411
TIGD2	-0.021402
ID4	-0.021399
KIF3C	-0.021394
SDHAF1	-0.021368
RHBDD3	-0.021288
SLC35B4	-0.021280
UBAP2	-0.021263
RILPL1	-0.021248
FAM50A	-0.021208
ERCC4	-0.021200
FAM57A	-0.021196
IPO13	-0.021194
DIRAS2	-0.021184
CDK5RAP1	-0.021174
C18orf8	-0.021121
C3orf38	-0.021103
P2RY1	-0.021064
KEAP1	-0.021054
INTS12	-0.021053
RAB3A	-0.021043
SMAD2	-0.021040
GTF2E1	-0.021039
ATG5	-0.021038
NOA1	-0.021008
FIZ1	-0.021001
PGP	-0.020987
MRPL55	-0.020986
PPCS	-0.020984
DIRAS1	-0.020977
MORC2	-0.020969
HILPDA	-0.020966
NUP93	-0.020966
GATA2	-0.020897
STAC	-0.020890
CDV3	-0.020854
RNF40	-0.020844
AXIN2	-0.020807
TRIM56	-0.020806
GALE	-0.020778
DOLPP1	-0.020750
CDK20	-0.020738
UBLCP1	-0.020726
ARMCX2	-0.020725
RNF34	-0.020723
TRIM8	-0.020699
GORASP1	-0.020654
MOB3A	-0.020637
LRWD1	-0.020628
C19orf44	-0.020620
MAPKAPK3	-0.020601
MIDN	-0.020558
SLC9A1	-0.020555
ARHGAP44	-0.020529
DNAJA3	-0.020515
IRGQ	-0.020510