!direction	-1
!num_genes	333
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Nilotinib
!smiles	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
!drugbank_id	DB04868
!pubchem_cid	644241
!cell_type	K562 cells
!organism	human
!end_metadata
NMU	-0.137738
MYC	-0.123566
VIM	-0.123350
LDHA	-0.115663
ASNS	-0.104556
IARS	-0.101242
ODC1	-0.096526
CHCHD2	-0.096425
CYCS	-0.095138
HNRNPA2B1	-0.092340
SOCS2	-0.092176
MTHFD2	-0.088239
GARS	-0.083555
H2BFS	-0.082427
ACTG1	-0.080759
ALDOA	-0.075721
RAN	-0.071891
LAPTM4B	-0.070796
TRIB3	-0.070698
SAMSN1	-0.069610
ENO1	-0.066181
DDIT4	-0.065096
HIST1H1C	-0.065033
SMYD3	-0.064693
IFITM2	-0.064607
PPA1	-0.063194
PRDX1	-0.062073
WARS	-0.061539
HINT1	-0.061121
NHP2	-0.060505
TMSB10	-0.060242
IFITM1	-0.060117
DDX21	-0.060003
MIF	-0.059303
NME1	-0.058483
TARS	-0.057869
MAT2A	-0.056677
ATF4	-0.056343
HSPA5	-0.055095
CTSH	-0.055028
KARS	-0.054495
GAPDH	-0.054076
VAPA	-0.053940
HNRNPAB	-0.053404
PFN1	-0.052602
PTMA	-0.052601
ATP5B	-0.052489
RSL24D1	-0.052190
NCL	-0.051652
CCT5	-0.050621
NPM1	-0.049229
CNBP	-0.049227
HSPD1	-0.049199
RAP1B	-0.049161
VDAC2	-0.048504
SLC7A5	-0.047577
YARS	-0.046986
NDUFAB1	-0.046765
H2AFZ	-0.046513
SNRPD2	-0.046417
XPOT	-0.046393
SARS	-0.046378
ACTB	-0.046266
SLIRP	-0.044845
NARS	-0.044761
TCEA1	-0.044256
MRPL3	-0.043891
NDUFS6	-0.043014
MCTS1	-0.042828
CD24	-0.042281
IFITM3	-0.042245
DDX5	-0.041651
CEBPB	-0.041472
PRDX4	-0.041262
GGCT	-0.041121
HIST1H4C	-0.040898
CFL1	-0.040887
SLC38A2	-0.040259
ATP5F1	-0.039462
SNRPG	-0.039116
DDX39A	-0.039044
LDHB	-0.038836
PGAM1	-0.038626
CMTM6	-0.037874
HSP90AB1	-0.037717
PTP4A2	-0.037057
EIF1	-0.036771
DLD	-0.036758
NDUFC2	-0.036401
SET	-0.036059
LYPLA1	-0.035625
LRPPRC	-0.035593
PHB2	-0.035570
C1QBP	-0.035441
PIM1	-0.034174
SNRPA1	-0.033849
SLC25A5	-0.033793
S100A11	-0.033620
GHITM	-0.033501
PRKCB	-0.033351
REXO2	-0.033286
CD69	-0.033272
HSPA9	-0.033135
HIST1H2BE	-0.032925
COX8A	-0.032914
POLR2G	-0.032487
MDH2	-0.031957
MDH1	-0.031811
PTGES3	-0.031756
AARS	-0.031732
ANXA1	-0.031596
PARK7	-0.031555
PTBP1	-0.031535
BHLHE40	-0.031381
SNRPD3	-0.031372
PPP1CC	-0.031223
EEF1B2	-0.031052
MYB	-0.031021
CAB39	-0.030915
ERH	-0.030887
CARS	-0.030830
LRRC47	-0.030798
EIF2S2	-0.030433
CTSC	-0.030194
RANBP1	-0.029835
CCNB1IP1	-0.029777
NOP10	-0.029677
HHEX	-0.029634
EIF4A1	-0.029625
RPS14P3	-0.029621
MRPS30	-0.029561
AMIGO2	-0.029539
UQCRFS1	-0.029507
PSMG1	-0.029482
TRA2B	-0.029297
NFE2L2	-0.029111
CKS1B	-0.029073
SRSF3	-0.029056
HAX1	-0.028752
C14orf2	-0.028223
IDH1	-0.028057
CLIC1	-0.027618
NQO2	-0.027602
LSM8	-0.027584
SMNDC1	-0.027443
AURKAIP1	-0.027313
DNAJC12	-0.027240
SEH1L	-0.027116
FAM60A	-0.026880
EIF3G	-0.026671
NDUFAF4	-0.026523
ZMPSTE24	-0.026249
SNRPF	-0.026063
AHCY	-0.025865
ARPC5L	-0.025700
HIRA	-0.025562
COX5A	-0.025490
YBX1	-0.025413
CCND2	-0.025399
PPIA	-0.025315
UFD1L	-0.025242
PRDX6	-0.025160
SSBP1	-0.025156
GAGE3	-0.025112
PGK1	-0.025099
FBL	-0.025015
OLA1	-0.024803
ARL4A	-0.024803
EIF4H	-0.024715
CCT4	-0.024679
HIST1H2BF	-0.024657
TUBB4B	-0.024651
CSNK2B	-0.024460
RAB27A	-0.024367
SRSF2	-0.024351
RPS16	-0.024338
ETFA	-0.024323
NDUFA13	-0.024182
RBMX	-0.024133
GLRX2	-0.024100
JTB	-0.024075
UBE2E1	-0.023952
MRPL15	-0.023944
ZNF706	-0.023877
UQCR11	-0.023673
NSA2	-0.023480
TUFM	-0.023469
RFC4	-0.023403
TXN	-0.023345
EGR1	-0.023299
DBF4	-0.023293
MAGEA3	-0.023265
CCT6A	-0.023127
ACTN4	-0.023103
FXYD5	-0.022986
SHMT2	-0.022895
UQCRQ	-0.022887
HMGB1	-0.022832
EIF4A3	-0.022778
CFAP20	-0.022672
DHX15	-0.022650
HSPE1	-0.022605
TUBB	-0.022573
SNRPB	-0.022557
FH	-0.022513
EIF3I	-0.022449
PSMA6	-0.022432
EDF1	-0.022427
MRPS35	-0.022341
SCD	-0.022340
ATIC	-0.022306
SLC25A6	-0.022201
SEC11A	-0.022177
MARS	-0.022176
HSPA14	-0.022169
TAF9	-0.022062
GTF3A	-0.021871
TPI1	-0.021851
MSN	-0.021840
CCT7	-0.021804
MTIF2	-0.021785
EIF4EBP1	-0.021599
PRMT1	-0.021499
NAE1	-0.021457
GTF2A2	-0.021392
HSD17B12	-0.021367
RPL26	-0.021336
H3F3B	-0.021313
DNAJC2	-0.021282
SPCS1	-0.021220
NHP2L1	-0.021199
VDAC1	-0.021134
TBPL1	-0.021082
FAM129A	-0.020985
SDF2L1	-0.020899
DYNLL1	-0.020867
EEF1D	-0.020866
PAICS	-0.020825
UQCRH	-0.020748
HERPUD1	-0.020669
NT5C2	-0.020628
UTP11L	-0.020605
SLC39A14	-0.020599
OPHN1	-0.020459
CELF2	-0.020440
CCT8	-0.020414
CENPU	-0.020379
SNRPD1	-0.020278
UTP6	-0.020216
NUP107	-0.020180
MAD2L1	-0.020164
EEF2	-0.020097
TRIAP1	-0.020072
RBM15	-0.020070
SERBP1	-0.020012
PSMA3	-0.019951
TMED2	-0.019947
RAC1	-0.019888
NDUFB4	-0.019768
UGP2	-0.019758
COCH	-0.019749
NOLC1	-0.019725
CBFB	-0.019684
CCT3	-0.019638
TIMM13	-0.019629
PPIB	-0.019600
HIST1H2AC	-0.019559
TBCA	-0.019555
MYL12B	-0.019507
RHOG	-0.019480
PHGDH	-0.019451
C14orf166	-0.019398
SFPQ	-0.019368
CISD1	-0.019356
STRAP	-0.019342
SYNGR3	-0.019342
SAE1	-0.019301
RAB11FIP1	-0.019185
BZW2	-0.019171
TOMM20	-0.019094
IMPDH2	-0.019032
LRRC59	-0.019009
POLR2H	-0.018991
GDF15	-0.018842
GPX4	-0.018780
GSTO1	-0.018780
UAP1	-0.018780
KRT18	-0.018761
UBE2N	-0.018734
SLC2A3	-0.018668
DKC1	-0.018635
TUBA1C	-0.018498
MAGEA6	-0.018397
NDUFV1	-0.018392
ATP5L	-0.018369
AGPAT5	-0.018282
UBE2S	-0.018281
PPIH	-0.018177
MTHFD1	-0.018165
POP7	-0.018151
FADS1	-0.018136
YRDC	-0.018020
CUTA	-0.018019
FNTA	-0.017963
MAPK6	-0.017944
HADHB	-0.017707
CAP1	-0.017686
TMED5	-0.017673
PBK	-0.017667
SRSF7	-0.017643
NAP1L1	-0.017594
MCM6	-0.017551
MAK16	-0.017545
SRP9	-0.017539
RPS29	-0.017538
AP2S1	-0.017523
IRAK1	-0.017510
IMP3	-0.017484
EMP3	-0.017418
ECHS1	-0.017417
CCDC59	-0.017366
RPS26	-0.017313
DDIT3	-0.017296
CTH	-0.017239
EIF3D	-0.017195
EZH2	-0.017193
ATP6V0B	-0.017134
NEDD8	-0.017117
PRR13	-0.017071
POGK	-0.017046
HIST1H2BK	-0.017012
ALG8	-0.017007
NDUFA1	-0.016984