!direction	-1
!num_genes	279
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	NICKEL CHLORIDE
!smiles	Cl[Ni]Cl
!pubchem_cid	24385
!cell_type	H4-II-E-C3 LIVER-derived cell line - 40 uM
!organism	rat
!end_metadata
FABP1	-0.069765
BAAT	-0.062331
ITIH4	-0.048732
GDF15	-0.046890
TM4SF20	-0.046428
DIXDC1	-0.044943
ANGPTL3	-0.042855
RAPGEF4	-0.042838
HAO1	-0.042236
ITIH2	-0.040202
TCEAL1	-0.039122
HMGCS2	-0.039010
LGALS2	-0.038146
TAP2	-0.037951
PFKFB1	-0.037205
ACKR4	-0.037173
SWI5	-0.036858
OLFML3	-0.036549
VTN	-0.036361
PDZK1	-0.035936
CCNG1	-0.035850
SERPIND1	-0.035593
ZMYND10	-0.035348
PIK3C2G	-0.035141
ALDOB	-0.034302
TAF15	-0.033872
ALOXE3	-0.033676
DDC	-0.033137
SPPL2A	-0.032056
CHGA	-0.031863
TPRKB	-0.031760
MIA3	-0.031586
RGS7	-0.031302
CLCNKB	-0.030795
C9	-0.030621
PCYOX1	-0.030596
IL18	-0.030474
PKM	-0.030145
SLC7A7	-0.029641
PIP5KL1	-0.029397
ANKRD44	-0.029349
SULT4A1	-0.029308
C5	-0.029102
ZNF335	-0.028880
FGA	-0.028706
GLIPR1	-0.028649
ZNF143	-0.028619
PAX4	-0.028363
FMN1	-0.028065
LRP5	-0.028027
PLK2	-0.027939
ID2	-0.027831
MFSD10	-0.027810
MSH3	-0.027777
APH1A	-0.027628
FGF21	-0.027573
FAM180A	-0.027549
SPSB4	-0.027325
MUC13	-0.027241
ABCA4	-0.026956
KCNH1	-0.026956
DAPL1	-0.026868
ANKS4B	-0.026815
MORN5	-0.026750
COL3A1	-0.026564
XPNPEP2	-0.026531
YIPF2	-0.026504
HSPA2	-0.026463
TCF19	-0.026390
RBM48	-0.026389
TAS2R1	-0.026332
TVP23A	-0.026242
DIO2	-0.026156
CAMKMT	-0.026145
EMILIN2	-0.025976
C11orf82	-0.025917
CIDEC	-0.025883
COL7A1	-0.025758
GGT7	-0.025646
MAL2	-0.025616
ST6GALNAC3	-0.025550
LCK	-0.025547
UGCG	-0.025486
HES2	-0.025448
USP29	-0.025405
PIK3R3	-0.025380
SPATA13	-0.025371
FABP2	-0.025355
ANO1	-0.025278
JMJD8	-0.025203
SULT1B1	-0.025191
APBB3	-0.025128
ARHGAP4	-0.024988
NR5A2	-0.024916
CDKN2B	-0.024908
NDC80	-0.024793
SLC38A7	-0.024768
CYSLTR1	-0.024724
GLRX	-0.024674
HPD	-0.024670
DMKN	-0.024628
DHX9	-0.024584
TRIM17	-0.024521
ANKRD9	-0.024518
ALPK2	-0.024422
UMOD	-0.024411
LPXN	-0.024381
DYRK3	-0.024328
NACC1	-0.024318
SAP25	-0.024279
DMPK	-0.024220
ARHGEF16	-0.024217
C12orf68	-0.024164
UBXN8	-0.024161
KNG1	-0.024125
CELSR3	-0.024109
APOBEC1	-0.024100
GTSE1	-0.024073
SPP2	-0.024018
PPAP2B	-0.023997
SLC2A2	-0.023944
CIDEB	-0.023874
ABCC6	-0.023805
PRSS21	-0.023696
NEU2	-0.023544
LAP3	-0.023529
GNMT	-0.023526
ST3GAL3	-0.023451
S1PR1	-0.023450
FKBP9	-0.023440
MYLK	-0.023439
TRIM45	-0.023379
PIDD	-0.023296
WFDC1	-0.023291
TTC12	-0.023048
POC1B	-0.022982
LAPTM4A	-0.022872
FMR1	-0.022859
MAP2K6	-0.022824
GPS2	-0.022775
PLA2G2D	-0.022750
ADIPOR2	-0.022736
NR1I3	-0.022682
TYW3	-0.022631
STK36	-0.022629
MEF2B	-0.022535
HEXIM1	-0.022490
HPGDS	-0.022401
CPT1B	-0.022395
TOB1	-0.022386
CRYAB	-0.022382
CTRC	-0.022319
SEC16B	-0.022295
THOC6	-0.022278
TNC	-0.022274
SORBS2	-0.022182
CXADR	-0.022139
FAM102B	-0.022131
GDPD1	-0.022119
RIMS3	-0.022090
ABCG4	-0.021960
IFI44	-0.021899
DLX5	-0.021865
PLA2G10	-0.021806
LPAR6	-0.021781
ZFP36	-0.021773
TRA2A	-0.021755
PTGFRN	-0.021734
ARHGEF26	-0.021732
LACTB	-0.021732
CHST10	-0.021726
PGPEP1	-0.021723
CYTH1	-0.021718
CNTN3	-0.021716
NUBPL	-0.021713
TCAIM	-0.021713
PPP1R17	-0.021694
DNAJB13	-0.021637
ARL14EP	-0.021490
HSD17B13	-0.021439
CYSLTR2	-0.021439
ZBTB9	-0.021427
ZHX2	-0.021422
TGM2	-0.021372
PIGR	-0.021317
SLAMF9	-0.021304
NDNL2	-0.021236
HSDL1	-0.021209
TTC30B	-0.021163
PGAM2	-0.021083
CLSTN3	-0.021066
RGN	-0.021056
CRP	-0.020946
CACNB4	-0.020928
MFAP2	-0.020910
GGACT	-0.020907
C8B	-0.020899
RPS6KA5	-0.020896
SLC10A3	-0.020870
WDR5B	-0.020869
KRT23	-0.020866
CLN6	-0.020857
EPS8L2	-0.020827
CXCR2	-0.020801
CLN3	-0.020745
CHTF8	-0.020738
IL2RB	-0.020719
ESYT3	-0.020671
BPIFA2	-0.020603
KCNH3	-0.020601
CCNA1	-0.020540
CPPED1	-0.020495
GPR19	-0.020416
RUFY1	-0.020415
PPY	-0.020403
MYOM2	-0.020369
RAB5C	-0.020352
RAB25	-0.020302
DOK3	-0.020294
CABYR	-0.020285
ITIH1	-0.020279
PLAG1	-0.020264
CPZ	-0.020261
PDZD2	-0.020211
GLRX3	-0.020143
UNC13C	-0.020132
TMEM59L	-0.020105
NUFIP2	-0.020055
MMP17	-0.020033
TNFAIP8	-0.020026
TTLL7	-0.020015
MAP1A	-0.019967
GLUL	-0.019931
GDF9	-0.019917
FAM46B	-0.019882
EML2	-0.019800
MTMR7	-0.019794
RABL3	-0.019777
CYBRD1	-0.019765
GALR1	-0.019759
ACRV1	-0.019744
CREM	-0.019708
BAK1	-0.019655
PIGH	-0.019611
CLDN2	-0.019566
MEIS2	-0.019549
GHR	-0.019523
TGFB3	-0.019512
ZNF846	-0.019509
PEX10	-0.019497
ZNF518A	-0.019495
PRDM11	-0.019490
ACBD5	-0.019473
CORO1A	-0.019461
WBSCR28	-0.019437
ABCA1	-0.019431
SCNN1A	-0.019397
CRTC3	-0.019385
MORN1	-0.019376
GNPDA2	-0.019350
NFE2L2	-0.019346
BPIFB2	-0.019337
FBXO15	-0.019336
SLC38A5	-0.019315
CCL4	-0.019287
TFCP2L1	-0.019262
EFHD1	-0.019242
HTATSF1	-0.019242
CFP	-0.019212
PTK2B	-0.019208
ELMO3	-0.019135
CXCR3	-0.019131
BBS9	-0.019115
VIP	-0.019096
SH3BGRL	-0.019067
LEO1	-0.019051
CALML4	-0.018996
FAM129A	-0.018982
ZCCHC9	-0.018979