!direction	-1
!num_genes	280
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Heroin
!smiles	CC(=O)OC1C=CC2C3CC4=C5C2(C1OC5=C(C=C4)OC(=O)C)CCN3C
!drugbank_id	DB01452
!pubchem_cid	5462328
!cell_type	striatum, day 24 withdrawal
!organism	mouse
!end_metadata
CSHL1	-0.432028
TTR	-0.297175
PRL	-0.295017
S100A5	-0.189033
NTN5	-0.129343
SLC17A7	-0.091965
NRN1	-0.088422
MYL4	-0.088415
C8orf46	-0.082831
SOX18	-0.077812
CDHR1	-0.072407
OMP	-0.071928
HBB	-0.069447
CCK	-0.066639
R3HDM2	-0.055915
TMEM178A	-0.047574
CA4	-0.047365
C2orf40	-0.045918
PLIN4	-0.044571
CLDN5	-0.043083
NPTX1	-0.043066
ERBB2IP	-0.042534
NEUROD2	-0.041422
ALAS2	-0.041376
AVP	-0.040525
IPCEF1	-0.040162
STAC2	-0.039542
TCAP	-0.038631
STMN1	-0.038158
GALNT9	-0.037767
TNNT1	-0.037437
STX1A	-0.037435
ACER2	-0.037294
CCL21	-0.036869
RASL11B	-0.036375
ELTD1	-0.036183
PCMTD2	-0.036164
TBR1	-0.036160
CPNE9	-0.035309
PTPRB	-0.034200
TH	-0.033857
FOXQ1	-0.033161
CNIH3	-0.033027
TSHZ3	-0.032453
KPNB1	-0.032381
FEZF2	-0.031715
MEDAG	-0.031570
NPPA	-0.031560
TEX40	-0.030780
PTGES3	-0.029609
XDH	-0.029272
NRIP3	-0.029075
SOX17	-0.029045
BHLHE22	-0.028340
SCGN	-0.028298
SLC30A3	-0.028116
CTGF	-0.027880
TNNC1	-0.027867
NECAB3	-0.027545
MMRN2	-0.027128
AQP1	-0.027045
FLT1	-0.026860
GATA2	-0.026830
VPS26B	-0.026473
ESAM	-0.026188
TRIM59	-0.026092
WFDC2	-0.025605
CRHBP	-0.025521
SLC6A3	-0.025474
COX2	-0.025125
H1F0	-0.024964
SELK	-0.024858
VAPA	-0.024713
EDN1	-0.024562
MLIP	-0.024535
SOWAHB	-0.024397
OLFML2B	-0.024210
ST18	-0.024108
KIAA1462	-0.024057
CCDC3	-0.023757
VWF	-0.023700
CHRD	-0.023625
MYL9	-0.023596
ATP6	-0.023571
VHL	-0.023201
NR4A2	-0.023059
ATP1B1	-0.022828
SPTSSA	-0.022755
CALB2	-0.022701
CPNE4	-0.022617
PSMD14	-0.022395
TEK	-0.022395
C17orf96	-0.022350
RASSF3	-0.022157
CHST8	-0.022129
NDUFB9	-0.022120
OTX1	-0.022081
DCTN1	-0.021970
CGA	-0.021841
PLTP	-0.021630
SEPT9	-0.021607
SLC2A1	-0.021507
MAF	-0.021370
TMEM108	-0.021326
RPRM	-0.021292
OLFM1	-0.021015
HS3ST2	-0.020994
DKK3	-0.020969
SATB1	-0.020735
OVOL2	-0.020702
TPPP	-0.019654
OTOP2	-0.019611
NFIX	-0.019588
ENPP2	-0.019585
CHRM3	-0.019555
SP7	-0.019549
PDLIM1	-0.019539
LBP	-0.019506
ACTA2	-0.019383
CD93	-0.019229
IGSF21	-0.018939
HAPLN4	-0.018894
JDP2	-0.018889
CBLN1	-0.018765
TMEM125	-0.018725
NCALD	-0.018554
TRHDE	-0.018551
IGFBP6	-0.018351
KLF2	-0.018341
KRT14	-0.018061
APCDD1	-0.017840
LINGO1	-0.017761
LHFP	-0.017682
HOMER2	-0.017678
DKKL1	-0.017525
TMEM204	-0.017510
HEPACAM	-0.017396
ISLR2	-0.017116
PLEKHA2	-0.017096
HSPB3	-0.017063
CCKBR	-0.017056
PRSS35	-0.016954
SEL1L3	-0.016765
KLHL40	-0.016741
FAIM3	-0.016732
FMN1	-0.016663
GJA4	-0.016627
CXCL12	-0.016557
ADAMTS19	-0.016548
ARHGAP15	-0.016543
EMX1	-0.016528
CYFIP2	-0.016504
NUDCD2	-0.016500
ATP5A1	-0.016387
PVALB	-0.016369
LRG1	-0.016329
LY6E	-0.016283
KCNAB3	-0.016247
IGF2	-0.016194
ATRNL1	-0.016153
MS4A15	-0.016092
ST8SIA5	-0.016078
TUBA1A	-0.016029
MYRIP	-0.015993
RAMP2	-0.015949
CHMP5	-0.015933
CALML4	-0.015891
TRIM37	-0.015871
TUBA8	-0.015839
LPAR1	-0.015783
COL24A1	-0.015729
RASL10A	-0.015696
GNA12	-0.015608
RGMA	-0.015589
PAMR1	-0.015548
PRSS12	-0.015509
SERPINI1	-0.015507
PAK1	-0.015507
LCT	-0.015503
ENG	-0.015491
MKX	-0.015416
RFNG	-0.015416
GFAP	-0.015373
ENC1	-0.015314
NOSTRIN	-0.015231
ALOX12B	-0.015213
CADPS2	-0.015162
PLS3	-0.015156
SNX7	-0.015129
GLTSCR2	-0.015124
IGFBP2	-0.015076
TRH	-0.015057
TANC1	-0.015006
MPPED1	-0.014995
IGFN1	-0.014969
LGR5	-0.014897
DDB1	-0.014854
GCA	-0.014839
SORBS3	-0.014729
C10orf54	-0.014614
STARD8	-0.014574
BCAS2	-0.014551
PIDD	-0.014544
FHIT	-0.014544
PRICKLE1	-0.014535
SLAIN1	-0.014524
ADCY4	-0.014496
TBX1	-0.014464
DAPK2	-0.014410
RGS5	-0.014345
NXPH4	-0.014281
SEC11C	-0.014281
S100A9	-0.014271
PGLYRP1	-0.014254
PLSCR3	-0.014244
FRZB	-0.014236
SYT13	-0.014218
ITM2A	-0.014206
SLIT1	-0.014125
MYLK	-0.014101
SLC26A4	-0.014089
COL5A1	-0.014069
KCNMB4	-0.014046
TBX21	-0.014042
UBE2QL1	-0.014027
ARHGEF19	-0.013916
OSBPL5	-0.013872
HKDC1	-0.013862
EHHADH	-0.013763
MAL	-0.013744
ICAM2	-0.013708
DLGAP1	-0.013704
LTBP4	-0.013677
KCNC4	-0.013642
OPTC	-0.013632
RELL1	-0.013630
KCNN4	-0.013615
GARNL3	-0.013559
VASN	-0.013474
ANKRD46	-0.013455
FXYD5	-0.013358
FHAD1	-0.013303
TPBG	-0.013279
TIE1	-0.013279
AGPAT3	-0.013219
HLA-DQB1	-0.013216
R3HDM4	-0.013202
CAV1	-0.013172
SLC39A10	-0.013132
DYNLT3	-0.013119
MOBP	-0.013054
CCDC109B	-0.013053
GPR21	-0.013004
CD74	-0.012984
IGFBP5	-0.012936
SEMA4C	-0.012888
NDRG1	-0.012879
ST6GALNAC2	-0.012875
RSPO3	-0.012816
NAP1L3	-0.012785
PECAM1	-0.012771
ACY3	-0.012749
MYO1F	-0.012741
VIP	-0.012722
ATP2A3	-0.012699
TPRN	-0.012693
WNT10A	-0.012691
TSPAN17	-0.012654
FLVCR2	-0.012645
PAIP2	-0.012639
LTV1	-0.012637
PICALM	-0.012632
MEX3D	-0.012631
HDAC7	-0.012562
DCT	-0.012551
WFDC1	-0.012545
LEPREL4	-0.012520
TF	-0.012512
ATP13A5	-0.012500
OPALIN	-0.012426