!direction	-1
!num_genes	191
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	MLN4924
!smiles	C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=O)N
!pubchem_cid	73014187
!cell_type	A375 melanoma cell line - 2 Hours
!organism	human
!end_metadata
UBC	-0.386869
UBB	-0.147873
COX1	-0.126515
IER3	-0.115947
S100A11	-0.092776
SLC26A2	-0.085453
LGALS1	-0.078770
COX2	-0.075136
SLC20A1	-0.070331
SERPINA3	-0.066033
SPRY2	-0.063729
ND2	-0.063659
RPS29	-0.060975
EEF2	-0.060199
MT2A	-0.060055
DKK1	-0.057956
ID1	-0.051244
FAM96B	-0.051028
RPS26	-0.049002
ID3	-0.048452
DANCR	-0.048234
TIPARP	-0.048063
CFL1	-0.047956
TPT1	-0.047356
USMG5	-0.046550
PKD1P1	-0.046057
MRPS24	-0.043872
IER2	-0.041890
KARS	-0.041821
LAMTOR5	-0.040605
TRIM28	-0.040559
KRT18	-0.039612
ACTN4	-0.038723
PPIB	-0.038498
NEAT1	-0.037725
H2AFZ	-0.037485
PSMB3	-0.037373
RAB1B	-0.036815
CHCHD2	-0.036704
SH3BGRL3	-0.036331
TMEM258	-0.035376
DYNLT3	-0.033911
H1F0	-0.033683
SNHG5	-0.033547
SLC25A6	-0.032965
RPL7L1	-0.032805
CD63	-0.032651
RARS	-0.032342
DDB1	-0.031891
RCC2	-0.031555
HYOU1	-0.031209
INHBA	-0.030924
PTDSS1	-0.030645
SOX10	-0.030585
PKM	-0.030076
IRS2	-0.029313
CDC25B	-0.029209
PARK7	-0.028760
PFN1	-0.028730
IFITM3	-0.028189
EIF3H	-0.028109
SRSF9	-0.027965
ADRM1	-0.027686
RPL6	-0.027439
HIST1H4C	-0.027162
GABARAP	-0.027130
FKBP1A	-0.026256
TMX2	-0.026256
HMGN3	-0.025877
SSR4	-0.025792
ATP5E	-0.025723
SNRPE	-0.025617
MANF	-0.025040
PSMB4	-0.025027
RAP1B	-0.024473
COX7A2	-0.024446
ATP6V0B	-0.024307
DYNLL1	-0.024111
CDC37	-0.024054
COX3	-0.023947
AAMP	-0.023662
HOXC6	-0.023643
SIGMAR1	-0.023559
RPS14P3	-0.023444
RPS11	-0.023269
BZW2	-0.023146
IGFBP4	-0.023015
OST4	-0.022937
GPI	-0.022593
LINC01419	-0.022448
EMP3	-0.022095
SHFM1	-0.021916
LOXL4	-0.021692
HNRNPK	-0.021636
POLR2G	-0.021314
MALAT1	-0.021309
UQCRH	-0.021201
RPL36A	-0.021121
PRKAR1A	-0.020980
PRDX4	-0.020954
RPF2	-0.020837
TMSB10	-0.020803
TMBIM6	-0.020627
FXYD5	-0.020527
NHP2	-0.020475
CMSS1	-0.020329
EEF1B2	-0.020316
LAMTOR4	-0.020233
MAP7D1	-0.020077
NOB1	-0.020000
MLF2	-0.019907
YWHAQ	-0.019845
POLR2F	-0.019723
STRAP	-0.019687
LGALS3BP	-0.019633
KIFAP3	-0.019354
RPL22	-0.019318
RPL24	-0.019301
RABGGTB	-0.019195
PSMD3	-0.019055
TPI1	-0.019047
CPSF7	-0.019027
PEBP1	-0.018912
ZFAS1	-0.018725
KCNN4	-0.018597
SLC5A3	-0.018596
MSRB1	-0.018525
ISCU	-0.018484
ATP5O	-0.018442
PRPF8	-0.018253
P4HB	-0.017899
PHB2	-0.017803
CMTM7	-0.017797
COL4A2	-0.017789
NDUFB11	-0.017675
ANP32B	-0.017640
TNC	-0.017600
CS	-0.017525
SLC34A3	-0.017471
C12orf57	-0.017461
GABARAPL2	-0.017318
ADI1	-0.017222
ATP1A1	-0.017112
SLC7A5	-0.017108
PMPCA	-0.017027
BTF3	-0.016844
RAB5C	-0.016816
SNHG7	-0.016799
GAR1	-0.016685
UFSP2	-0.016667
LINC00657	-0.016637
EMC4	-0.016539
C14orf2	-0.016519
IL13RA2	-0.016354
ATP6V0C	-0.016348
ND6	-0.016301
MORF4L1	-0.016299
CDK2AP1	-0.016249
DDX21	-0.016215
DDB2	-0.016113
SNHG19	-0.016096
TTC19	-0.015991
HDGF	-0.015886
MYOF	-0.015852
C1orf131	-0.015821
DUSP10	-0.015820
RPL29	-0.015806
LAMP1	-0.015703
TUBA1A	-0.015624
HGS	-0.015590
GNL3	-0.015571
HAX1	-0.015546
OPHN1	-0.015365
RPS3A	-0.015241
NDUFA13	-0.015110
ATP1B1	-0.015105
UBE2E1	-0.015089
SPCS1	-0.015075
RCN1	-0.015064
ATXN10	-0.015052
TBCB	-0.015049
CFAP36	-0.015008
GNAS	-0.015000
EIF4A2	-0.014942
SNX17	-0.014820
PTRF	-0.014811
MYBL2	-0.014790
SRPR	-0.014741
TUBB4B	-0.014736
BSG	-0.014687
FST	-0.014673