!direction	-1
!num_genes	377
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	PD173074
!smiles	CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C
!pubchem_cid	1401
!cell_type	MGHU3 bladder cancer cells
!organism	human
!end_metadata
FAM111B	-0.050167
TCN1	-0.050140
XRCC2	-0.049863
PBK	-0.048446
CLSPN	-0.048372
DTL	-0.047803
DSCC1	-0.046428
HIST1H3B	-0.045759
BRCA1	-0.045052
WDHD1	-0.044691
POLE2	-0.044310
SPRED1	-0.043908
HIST1H1B	-0.043861
PRIM1	-0.043744
RAD51AP1	-0.043624
BLM	-0.043621
CDK1	-0.043321
CDC45	-0.043264
TRIP13	-0.043260
HIST1H2BM	-0.043158
CENPK	-0.042788
MELK	-0.042634
PLK4	-0.042620
RAD51	-0.042543
CDCA7	-0.042409
RFC3	-0.041984
WDR76	-0.041962
GINS2	-0.041878
KIF15	-0.041846
MCM8	-0.041651
CCNE2	-0.041633
RRM2	-0.041565
MCM6	-0.041565
MMS22L	-0.041539
SPC25	-0.041468
MCM10	-0.041437
DDIAS	-0.041400
RBL1	-0.041185
CKAP2L	-0.040814
MAD2L1	-0.040801
KIAA1524	-0.040762
TYMS	-0.040734
RFC4	-0.040727
MND1	-0.040319
KIF23	-0.040197
C18orf54	-0.040148
NCAPH	-0.040094
CDC6	-0.040071
ORC1	-0.040049
GINS1	-0.039835
CHEK1	-0.039760
FANCI	-0.039757
EXO1	-0.039649
TTK	-0.039590
STIL	-0.039445
SGOL1	-0.039412
KIF14	-0.039392
NCAPG2	-0.039226
NUF2	-0.039122
CCNA2	-0.039094
KIF11	-0.039075
PRC1	-0.039066
HJURP	-0.038922
HIST1H2AB	-0.038376
HIST1H2BB	-0.038249
GSDMC	-0.038195
CDC7	-0.038194
CCNE1	-0.038193
HMMR	-0.037891
CMSS1	-0.037825
ATAD5	-0.037782
ANLN	-0.037708
CENPH	-0.037528
SHCBP1	-0.037493
CENPE	-0.037451
RRM1	-0.037414
MYBL2	-0.037311
TIPIN	-0.037304
CDC25A	-0.037279
ORC6	-0.037239
CDKN3	-0.037050
FOXM1	-0.036910
TLR4	-0.036809
CEP78	-0.036781
NDC80	-0.036762
SPC24	-0.036564
CENPI	-0.036383
PLK1	-0.036372
TOP2A	-0.036188
BRIP1	-0.035805
HIST1H3A	-0.035785
KIF20B	-0.035724
CDCA5	-0.035673
DLGAP5	-0.035458
TICRR	-0.035451
SPDL1	-0.035253
SKA1	-0.035136
BUB1	-0.035098
DEPDC1	-0.035012
KIF4A	-0.034989
SMC2	-0.034959
HELLS	-0.034913
KIF2C	-0.034908
DUSP6	-0.034807
LMNB1	-0.034724
MCM7	-0.034711
ASF1B	-0.034704
FANCD2	-0.034697
MTFR2	-0.034508
CEP55	-0.034314
E2F7	-0.034304
ECT2	-0.034292
HIST1H2AK	-0.034268
AGPAT9	-0.034244
CDCA2	-0.034091
ARHGAP11A	-0.033959
TEX30	-0.033866
AUNIP	-0.033836
AURKA	-0.033778
CASC5	-0.033766
ITGA2	-0.033759
KNTC1	-0.033728
SASS6	-0.033691
DIAPH3	-0.033686
KNSTRN	-0.033572
ASPM	-0.033555
ERCC6L	-0.033541
CCNB1	-0.033507
MKI67	-0.033482
FIGNL1	-0.033480
POLQ	-0.033479
DHRS9	-0.033460
TPX2	-0.033342
ESCO2	-0.033291
MCM4	-0.033221
BRCA2	-0.033174
KIF18A	-0.032992
MCM5	-0.032959
TACC3	-0.032888
NCAPD3	-0.032858
HIST1H3F	-0.032717
DSN1	-0.032692
CDCA8	-0.032516
POLA2	-0.032512
DNA2	-0.032348
NUSAP1	-0.032335
HIST1H4D	-0.032183
FBXO5	-0.032182
PRR11	-0.032136
RAD54L	-0.032085
UBE2T	-0.032016
MCM2	-0.031979
SGOL2	-0.031950
KRT6A	-0.031902
SLC16A1	-0.031655
ZWINT	-0.031629
MYEOV	-0.031441
SPRED2	-0.031356
GPSM2	-0.031245
OIP5	-0.031221
C5orf34	-0.031212
ADCY3	-0.031211
TK1	-0.031134
DEPDC1B	-0.031029
HIST2H4A	-0.031008
HIST2H4B	-0.031008
KIAA0101	-0.030875
RAD54B	-0.030779
HIST1H2AJ	-0.030689
MNS1	-0.030595
LYAR	-0.030464
CENPF	-0.030277
VRK1	-0.030251
CENPW	-0.030150
CIT	-0.030150
RFC2	-0.030123
POLA1	-0.030074
HIST1H4A	-0.030053
FANCB	-0.030044
CENPU	-0.029867
LIN9	-0.029835
KIFC1	-0.029804
CCNB2	-0.029765
DCLRE1B	-0.029720
NEIL3	-0.029676
CHAF1B	-0.029580
SACS	-0.029562
FEN1	-0.029548
CHRNA5	-0.029460
NEK2	-0.029389
TUBG1	-0.029079
HIST1H2AI	-0.029077
UBE2C	-0.029055
IL18	-0.028986
ATAD2	-0.028834
MCM3	-0.028672
MSH2	-0.028634
GINS4	-0.028592
ARHGAP11B	-0.028316
HIST1H3C	-0.028300
RACGAP1	-0.028289
RTTN	-0.028216
ETV4	-0.028203
FANCG	-0.028184
CYP24A1	-0.028128
RFC5	-0.028002
TMPO	-0.027975
PSAT1	-0.027844
MPHOSPH9	-0.027814
GSG2	-0.027634
CDCA3	-0.027631
UBE2S	-0.027629
CENPL	-0.027622
HIST1H2BI	-0.027544
PADI4	-0.027459
GTSE1	-0.027441
HIST2H2AB	-0.027439
EZH2	-0.027330
HIST1H4L	-0.027244
AURKB	-0.027232
C4orf46	-0.027221
CD44	-0.027107
PARPBP	-0.027103
C17orf53	-0.027056
CKS2	-0.027049
HIST1H2AL	-0.027008
GINS3	-0.026807
FAM83D	-0.026805
CCNF	-0.026797
POLD3	-0.026715
MDC1	-0.026653
SERPINB3	-0.026650
HIST1H2BF	-0.026626
HIST1H3G	-0.026599
DONSON	-0.026483
NETO2	-0.026474
ZNF850	-0.026465
PKMYT1	-0.026376
LOC81691	-0.026328
RFWD3	-0.026265
EME1	-0.026213
CDCA4	-0.026156
FANCA	-0.026114
ERRFI1	-0.025996
HMGB2	-0.025824
ANP32E	-0.025810
ESPL1	-0.025727
IQGAP3	-0.025701
PSMC3IP	-0.025519
ZRANB3	-0.025516
GJC1	-0.025513
HIST1H2AH	-0.025457
KPNA2	-0.025439
SLC25A19	-0.025374
PLEK2	-0.025370
MTBP	-0.025354
CEACAM1	-0.025282
LRRC8C	-0.025274
RAD18	-0.025208
MIS18A	-0.025134
NUP107	-0.025103
TMEM106C	-0.025094
CNTN1	-0.025091
CKS1B	-0.025020
MYC	-0.024999
MTHFD1	-0.024983
KIF18B	-0.024950
CENPA	-0.024884
NCAPD2	-0.024848
HIST1H2BH	-0.024712
RIBC2	-0.024696
ITGB5	-0.024669
CTNNAL1	-0.024665
RANBP1	-0.024504
CCND1	-0.024473
PNP	-0.024453
RNASEH2A	-0.024397
NRP2	-0.024347
NUP155	-0.024330
PHF19	-0.024209
ITGA6	-0.024103
SLC1A3	-0.024098
CHEK2	-0.024053
TIMELESS	-0.023979
HIST1H2AM	-0.023978
HIRIP3	-0.023960
PPP4R4	-0.023922
POLR1E	-0.023850
SLC25A15	-0.023815
ZGRF1	-0.023813
NDC1	-0.023771
TROAP	-0.023673
RUVBL1	-0.023576
POLR3G	-0.023503
MRTO4	-0.023400
C19orf48	-0.023331
TTF2	-0.023330
PROCR	-0.023222
CAD	-0.023006
POLE	-0.022953
SUV39H1	-0.022819
TMEM194A	-0.022766
CCDC34	-0.022677
HIST1H2AE	-0.022625
ANXA10	-0.022622
DNMT1	-0.022616
MASTL	-0.022597
RPA2	-0.022590
USP1	-0.022465
IPO4	-0.022460
KIF24	-0.022441
TUBA4A	-0.022429
TMEM109	-0.022389
HIST1H1D	-0.022351
MB21D1	-0.022306
CEP128	-0.022288
S100A2	-0.022283
PAICS	-0.022272
HIST1H4B	-0.022270
HAL	-0.022266
EXOSC2	-0.022152
EXOSC8	-0.022137
S100A3	-0.022132
MYBL1	-0.022072
OXCT1	-0.022048
C1orf112	-0.022031
CENPM	-0.022017
SNORD28	-0.021989
TUBA1B	-0.021918
SUV39H2	-0.021909
PPAT	-0.021897
CTPS1	-0.021889
PLA2G4A	-0.021854
RPGRIP1L	-0.021847
BARD1	-0.021677
SFXN2	-0.021648
HSPA4L	-0.021603
DTYMK	-0.021565
KIF22	-0.021526
CEP152	-0.021496
OSGEPL1	-0.021483
PRPS2	-0.021460
SAAL1	-0.021420
UCK2	-0.021418
CDK2	-0.021413
HAUS8	-0.021314
RAB23	-0.021186
IL7R	-0.021093
HIST1H2BL	-0.021087
SLC20A1	-0.021061
CKAP2	-0.021016
TOPBP1	-0.020975
SCML1	-0.020953
BAG2	-0.020936
CENPQ	-0.020919
H2AFZ	-0.020879
ITGB3BP	-0.020863
BIRC5	-0.020830
PRNP	-0.020826
SMC4	-0.020805
BNIP3	-0.020764
ZNF485	-0.020640
TMC7	-0.020609
CDT1	-0.020599
DUT	-0.020551
NASP	-0.020538
H2AFX	-0.020515
CHAC2	-0.020506
MYO19	-0.020504
IKBIP	-0.020460
ZNF367	-0.020351
TYRO3	-0.020235
CHAF1A	-0.020205
SFXN1	-0.020196
HIST1H3H	-0.020189
NUP93	-0.020189
HIST1H3I	-0.020142