!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!cell	MCF10A 
!perturbation	MEK1(S217S221) transfection
!gene	MAP2K1 (MEK1)
!entrez gene	5604
!disease	Breast cancer
!end_metadata
HRAS	0.455480
HSPB1	-0.145480
RRM2	0.126790
DEK	0.116029
KRT15	-0.103866
HSPA1A	0.095745
KRT16	-0.092952
H2AFZ	0.089105
MAFB	-0.087115
PTMA	0.085977
SNRPG	0.080899
IFITM3	0.079632
SNRPB	0.078134
PCNA	0.072356
TMSB10	-0.071493
HMGN2	0.069154
SPRR1B	-0.066076
HIST1H2BK	0.063975
NDUFA1	-0.063647
ISG15	0.061973
MTHFD1	0.061921
FXYD3	-0.061894
CSTA	-0.061525
HSPE1	0.061182
MAD2L1	0.060863
KIAA0101	0.060220
HSPA8	0.059547
ANP32B	0.059011
DSG3	-0.058896
RBBP7	0.058226
FLRT3	-0.058058
PRDX5	-0.056564
SLBP	0.056487
HSP90AA1	0.056208
DDX39A	0.055783
PNRC1	-0.055468
DDX21	0.055423
UHRF1	0.054409
BTG1	-0.054186
CES2	-0.053814
ZWINT	0.052784
UNG	0.052367
RPL26	-0.051828
ATP1B3	-0.051803
MCM2	0.051777
SNRPD2	0.051524
ACTN4	-0.050771
SFN	-0.050219
SLC25A6	-0.049710
UBA2	0.049398
AHNAK2	-0.048481
HMGN3	-0.048428
JUP	-0.047756
NCL	0.047527
NGFRAP1	-0.047519
CDK2AP1	0.046504
TUBA1B	0.046482
GMNN	0.046376
SUMO2	0.046201
COL17A1	-0.045490
MRFAP1	0.045422
MAL2	0.045167
IFIT1	0.044523
PABPC3	0.044504
NHP2	0.044431
FAM96A	0.044373
CCDC51	-0.044175
EIF4EBP1	0.043645
PTGES3	0.043593
CLCA2	-0.043572
RPS25	0.043431
H2BFS	0.043040
CAV1	-0.042979
RRM1	0.042697
MRPL3	0.042638
SERPINB5	-0.042597
NAE1	0.042516
OAZ1	0.042480
XPOT	0.042420
CCT3	0.042074
NEAT1	-0.041888
PSMG1	0.041272
AIM1	-0.041099
ODC1	0.040881
TUBA1C	0.040694
ITGA6	-0.040600
NME1	0.040368
S100A14	-0.040328
SRP9	0.040107
GOT2	0.039831
MIR22HG	-0.039689
TYMS	0.039337
DNMT1	0.039295
RAN	0.039274
IFITM2	0.039163
TUBB	0.039113
RGS2	-0.039001
TKT	-0.038999
TRMT112	0.038971
SNRPD3	0.038944
IARS	0.038931
LAP3	0.038745
S100A11	-0.038577
IL18	-0.038550
TCEAL4	-0.038545
GLO1	0.038144
CS	-0.037881
NOP58	0.037795
FBL	0.037548
RPL41	0.037074
EFEMP1	-0.036981
ENOPH1	0.036963
KRT5	-0.036884
CMSS1	0.036646
MAPK6	-0.035746
IFITM1	0.035606
GTF3A	0.035119
MCM7	0.035072
CD24	-0.034909
RPS14P3	-0.034898
NDUFB9	-0.034891
KRT10	-0.034877
SOD1	0.034624
GJB2	0.034200
KRT6B	-0.034156
MT2A	0.033984
MCM6	0.033974
S100A16	-0.033826
KPNB1	0.033767
ARL6IP5	-0.033734
ATF4	0.033689
HADHB	-0.033689
SNHG8	-0.033465
SET	0.033317
SULF2	-0.032954
HMGB1	0.032833
TRMT5	0.032770
TIMP1	0.032603
HNRNPAB	0.032505
SDCBP	-0.032503
MIR205HG	-0.032401
GABARAP	-0.032198
GSTP1	-0.032148
IFIT3	0.032146
PPL	-0.032132
SRSF2	0.032103
IRX3	-0.032081
UGP2	-0.031958
CCT6A	0.031920
PUS7	0.031712
GLUL	-0.031597
QARS	-0.031490
TOB1	-0.031460
ISCU	-0.031418
YWHAG	-0.031323
B2M	0.031268
YWHAZ	-0.031267
TUBB4B	0.031225
LGALS1	-0.031085
VDAC2	-0.031017
IFRD2	0.030898
NPM1	0.030894
CDH1	-0.030857
PARP1	0.030738
GPR87	-0.030679
C19orf33	-0.030644
SGK1	-0.030638
CDK4	0.030551
ATP5B	-0.030421
UFC1	0.030338
RPL22L1	0.030195
RFC4	0.030186
RPL30	0.030048
ASUN	0.029940
MCM3	0.029930
DHRS1	-0.029738
DUT	0.029653
RPL39	0.029602
RPL34	-0.029578
TOMM5	0.029535
JTB	0.029489
RPS5	0.029445
GARS	0.029425
C3	-0.029359
HLA-A	0.029224
MRPL17	0.029219
LDHB	0.029167
RPL9	0.029111
MYL6	-0.028990
CKS2	0.028868
HNRNPK	0.028747
WBP5	-0.028477
RPF2	0.028399
RPA2	0.028318
PRDX4	0.028316
SLPI	-0.028269
TMEM123	0.028223
CDKN1A	-0.028065
DHX15	0.028054
PTPLAD1	0.028013
SNHG19	-0.028003
SNAI2	-0.027958
CAPNS1	-0.027945
PSMD14	0.027925
ACTB	0.027916
SLC38A2	-0.027834
RPS13	0.027649
PNPT1	0.027506
PDLIM1	-0.027478
KPNA2	0.027446
MRPL51	-0.027419
DSC3	-0.027410
CHCHD10	-0.027394
SLC43A3	0.027393
FEN1	0.027387
RPL21	0.027343
TUBA4A	0.027308
RPL23A	0.027299
GGH	0.027249
CBWD1	0.027222
CCT2	0.027201
PLSCR1	0.027182
TGFBI	-0.027053
CCDC109B	0.027022
FABP5	0.027010
ADRB2	-0.027003
NDUFB5	-0.026994
TRIM22	0.026856
ND2	-0.026715
PTPLB	-0.026642
RPS3	0.026581
CAV2	-0.026531
MTHFD2	0.026431
CACYBP	0.026374
FKBP5	-0.026295
ZBTB16	-0.026235
ATIC	0.026175
FGFR3	-0.026123
TUBG1	0.026075
DTL	0.025976
HNRNPR	0.025957
ZNF367	0.025931
NAA50	0.025866
HAT1	0.025775
CDH3	-0.025690
CKS1B	0.025669
RNF138	0.025614
TRIM29	-0.025566
DEGS1	0.025533
C1orf116	-0.025427
UBE2T	0.025424
HSPD1	0.025338
CSE1L	0.025310
RPS10	0.025242
SERBP1	0.025169
ILF2	0.025147
POLR2K	0.025113
AKR1C3	-0.025026
EEF2	-0.025024
UBE2S	0.024961
SLC1A5	0.024926
ARPC3	0.024915
LMNB1	0.024911
MFAP5	-0.024818
KRT18	0.024810
DDR1	-0.024756
HSP90AB1	0.024745
AKR1C2	-0.024729
UQCRH	-0.024645
RPL14	0.024637
LBR	0.024568
SRP14	0.024535
TRA2B	0.024432
CBX3	0.024356
CECR5	0.024346
NOP10	0.024324
EEF1B2	0.024305
OAS1	0.024256
CCDC6	-0.024179
PRC1	0.024161
RPL6	-0.024096
POLE3	0.024095
SNRPD1	0.024090
ALDH9A1	-0.024066
RPL24	0.024058
COX8A	-0.024055
HMGB2	0.023951
ASS1	-0.023945
PRDX1	0.023883
KRT17	-0.023812
CTSD	-0.023756
TXNIP	-0.023750
C14orf166	0.023662
IFI16	0.023623
STAT1	0.023614
HIF1A	-0.023613
NCOA4	-0.023585
PM20D2	0.023486
TMA7	-0.023435
STOM	-0.023426
HDGF	0.023405
SLIRP	0.023314
AP2S1	0.023255
PDIA6	0.023223
AP3S1	-0.023170
PSAP	-0.023121
TMEM258	0.023120
LAMB3	-0.023099
NFE2L1	-0.022983
GRN	-0.022982
PPA1	0.022974
PEBP1	0.022942
LEPREL1	-0.022926
ADH5	-0.022894
PPIB	0.022863
IFI44L	0.022831
SHFM1	0.022830
TMEM97	0.022783
PPTC7	-0.022783
IRF6	-0.022777
RPSA	0.022731
CENPK	0.022708
TBCA	0.022650
SLC39A4	0.022643
ABCB10	0.022634
DLEU1	0.022612
SERPINB7	-0.022511
C1QBP	0.022451
UBE2E3	0.022437
SDC1	-0.022416
EIF1AX	0.022397
KCTD3	0.022394
VAMP8	-0.022377
HTRA1	-0.022354
CHP1	-0.022350
AJUBA	-0.022347
NOTCH2NL	-0.022280
RPS2	0.022264
SRM	0.022169
NOLC1	0.022156
IRAK1	0.022108
VARS2	-0.022077
ATAD2	0.022053
CCNE2	0.022033
COX7A2L	-0.022014
EXOSC8	0.021970
PSAT1	0.021927
YWHAE	0.021875
RPL11	0.021839
NDRG1	-0.021831
SEMA3F	-0.021800
GADD45A	-0.021753
RPL3	-0.021751
CHST2	-0.021739
SLC39A10	-0.021732
LINC00657	-0.021713
HS6ST2	0.021706
COA6	0.021705
UQCRC1	-0.021677
PAICS	0.021667
NFKBIA	-0.021667
COX6C	-0.021636
SHC1	-0.021613
ADAR	0.021581
MRPL32	0.021569
RAP1B	-0.021548
RPL15	-0.021470
MAOA	-0.021462
TAX1BP3	-0.021431
PSMB6	-0.021260
DTX3L	0.021203
KLK5	-0.021184
RARS	-0.021180
LYPLA1	0.021058
SUMO4	0.020994
RPS26	0.020976
NDFIP2	-0.020961
PGAM1	0.020925
IL20RB	-0.020919
SPCS1	0.020890
PFDN2	0.020887
HLA-C	0.020875
MKNK2	-0.020856
PTPN14	-0.020851
ID3	-0.020776
ORC6	0.020771
ATP6	0.020735
POLR2H	0.020706
CALM2	0.020671
RPS4X	0.020667
COX7A2	-0.020633
CCT7	0.020618
ABCE1	0.020612
NT5C3A	0.020589
NDUFS6	-0.020586
HMGN1	0.020585
MEA1	0.020579
TMEM14B	0.020552
TPX2	0.020548
KARS	0.020531
NAP1L1	0.020463
SSRP1	0.020462
KCTD12	0.020451
SSB	0.020359
ACTL6A	0.020337
NOC3L	0.020292
DST	-0.020287
TCEB1	0.020268
SRSF9	0.020257
CTPS1	0.020213
CEBPB	-0.020182
CEP55	0.020156
MMADHC	0.020138
KLF10	-0.020138
PIK3C2B	-0.020086
RABAC1	-0.020012
CD81	-0.019971
TGFBR3	-0.019772
S100A10	-0.019689
SNRPE	0.019686
RHOD	-0.019676
RAB9A	-0.019652
SESN1	-0.019647
PDCD4	-0.019605
MYBL2	0.019601
GYG1	0.019596
CD3EAP	0.019583
XRCC5	0.019568
LAMB1	-0.019565
RPS8	0.019531
RPL8	0.019526
PSMA1	0.019484
LAMA5	-0.019470
RAD21	0.019467
TCP1	0.019451
PPIL1	0.019442
SERTAD1	-0.019418
DNAJA1	0.019407
CDC123	0.019405
PKM	-0.019394
DUSP14	-0.019359
CST3	-0.019341
RPL12	-0.019321
NEK7	-0.019296
DNTTIP2	0.019282
FAM96B	-0.019262
ABHD17A	0.019249
RANBP1	0.019238
PHLDA2	0.019106
NNMT	0.019102
TPRKB	0.019084
AMZ2	-0.019059
CALR	0.019034
LIMK2	-0.018979
LDHA	0.018900
DONSON	0.018868
SH3BGRL	-0.018852
TP53I3	-0.018846
EIF3J	0.018830
CHAMP1	0.018658
RND3	-0.018655
CBX1	0.018652
TPI1	0.018607
KLF5	-0.018603
PTBP1	0.018589
NDUFA13	-0.018587
OST4	-0.018573
RAB7B	-0.018517
CHAC2	0.018464
GSTO1	0.018453
DDX60	0.018435
ERH	0.018370
EIF4A2	-0.018366
LAMTOR1	-0.018345
BCAP31	-0.018341
GLTSCR2	-0.018331
DHFR	0.018316
DNER	-0.018315
RAD51AP1	0.018306
DBF4	0.018214
BRI3BP	0.018209
SRSF7	0.018180
SLC25A5	-0.018150
HPRT1	0.018138
SLC22A5	-0.018043
ALDH18A1	0.018017
PET100	-0.017972
VPS51	-0.017964
NUDT15	0.017958
SNRNP25	0.017956
PTTG1IP	-0.017938
MSLN	-0.017934
ZMAT3	-0.017933
TSPAN13	0.017916
TRIM28	0.017891
PSMC1	0.017887
MSMO1	-0.017875
ATP1B1	-0.017861
CD109	-0.017854
TPT1	0.017853