!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	4-Hydroxytamoxifen
!smiles	CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
!pubchem_cid	449459
!cell_type	MCF7 breast cancer cells - 100nM
!organism	human
!end_metadata
IER3	0.255885
PABPC3	-0.178117
NQO1	-0.177539
LDHA	0.160183
AGR2	0.146503
LCN2	-0.142421
TFF1	-0.135223
KPNA2	0.132784
SERPINA3	-0.126584
EEF1B2	0.121188
NACAP1	-0.120056
PRDX1	-0.114058
HIST1H4C	0.113164
KRT18	-0.109220
NFKBIA	-0.106066
TPD52L1	0.105061
LXN	-0.098758
LAPTM4A	0.091559
RPL41	-0.088191
TMEM64	0.087264
CSTA	-0.084179
RPL27	0.083571
UBC	-0.082854
COX2	-0.082700
IFIT1	0.081871
KRT19	0.079897
ATP6	-0.079103
ISOC1	0.075778
FBP1	-0.074826
RPL36A	0.072453
GGCT	0.072138
MIF	0.069807
RPS13	0.069385
COX6C	-0.067725
NHP2	0.067444
RPL30	-0.065876
COX8A	0.062928
RPS14P3	0.062544
HIF1A	0.062271
PTTG1	0.061476
S100P	-0.059965
TBCA	0.059765
SULF2	0.059436
CKS2	0.057366
ISG15	0.056882
MYL12A	0.056529
RPL24	0.056290
RPL21	0.056119
DPM1	0.054440
ARPC3	0.054350
RPS23	-0.054013
RPL34	-0.053409
CYC1	0.053234
HSPE1	0.053170
HLA-DRB1	0.052395
BAMBI	-0.051829
MALAT1	-0.050793
DYNLL1	0.050528
C14orf166	0.050214
PTGES3	0.049922
H2AFZ	0.049868
CXXC5	0.049380
GATA3	-0.049224
RND1	-0.049209
S100A9	-0.049152
SHFM1	0.049022
RPS4X	-0.049007
PPA1	0.048869
TUBA1C	0.048146
YBX1	0.047969
IGFBP3	-0.047925
HSPB1	0.046883
SLIRP	0.046614
NGFRAP1	-0.046490
BCAS2	-0.046490
TUBB4B	0.046419
FTL	0.046183
UBE2C	0.046137
LGALS3	-0.045739
BCAS3	-0.045442
CDK2AP1	0.045074
TMA7	0.045034
TMSB10	-0.044803
TUBB	0.044307
RPS9	0.044296
TPT1	-0.043917
IFI27	0.043573
KIAA0101	0.043510
PGAM1	-0.043462
NDUFA13	0.043090
RAN	0.043018
MYL12B	-0.042857
HMGN3	0.042645
NFKBIZ	-0.042171
ATP5B	0.042087
NDUFB9	0.042026
SLC39A6	-0.041951
RPS25	0.041861
FTH1P5	-0.041680
C20orf24	0.041679
KARS	0.041395
ATP5L	0.041262
CHCHD1	0.041250
CYP1B1	-0.041233
ACTB	-0.041061
RPL37A	-0.040982
PABPC1	-0.040872
NME1	0.040566
PRDX4	0.039947
GNB2L1	-0.039232
PARK7	0.039137
FAU	0.038511
RPL39	-0.038467
CHCHD2	0.038353
CA2	0.038134
ETFA	-0.038064
KRT8	-0.038013
HMGB2	0.037754
MYL6	-0.037451
FBL	0.037406
HINT1	0.037366
MMADHC	0.037222
ATP5J	0.037158
TKT	0.037151
AKR1C3	-0.037109
PHB2	0.036926
HSPA1A	0.036873
ECH1	-0.036744
EEF1A1	-0.036624
NPTN	0.036611
ITGAV	-0.036576
RPS10	-0.036455
RPL17	0.036256
SLC35A1	-0.036227
UQCRFS1	0.035921
NDUFAB1	0.035773
DDX5	0.035772
TALDO1	0.035703
YWHAZ	-0.035561
DAD1	0.035141
VAMP8	-0.034959
MRPL3	0.034803
TUBA1B	0.034733
SNHG6	0.034657
FAM102B	-0.034498
RPL6	0.034157
TPI1	0.033783
NDUFA1	0.033726
COX7C	0.033724
TMEM258	0.033654
RPL13A	0.033433
EEF2	-0.033332
SNRPF	0.033316
PRC1	0.033292
SRP9	0.032772
ZWINT	0.032677
COX7A2	0.032464
UBE2S	0.032419
USMG5	0.032177
RPS5	0.032017
GSTM3	-0.031973
BZW2	-0.031966
NEAT1	-0.031950
CDK1	0.031924
IFITM1	0.031890
SEC61B	0.031578
GNPNAT1	0.031569
TXN	0.031279
PDIA6	0.031209
WWP1	-0.031190
BNIP3	0.031103
AP1S1	0.031055
CSTB	-0.030871
RPS3	0.030799
CLIC3	0.030786
ALDOA	0.030685
SF3B5	0.030620
RPL32	-0.030287
RPL29	0.030262
GTF3A	0.030191
FUCA2	0.030169
TCEAL4	0.030069
ATP6AP1	-0.030043
AGR3	0.030019
RPL19	0.030015
RASGRP1	0.029965
CKS1B	0.029935
B2M	-0.029770
SNRPD3	0.029760
PSMA4	0.029508
NPM1	0.029440
ADAR	-0.029251
TUBB3	0.029092
ZNF217	-0.029028
MYC	0.028980
EBPL	0.028940
PNRC1	-0.028684
NAP1L1	0.028584
BPIFA4P	-0.028528
SET	0.028497
TXNRD1	0.028415
PFN2	0.028392
ERH	0.028237
MRFAP1	0.028055
COX7A2L	0.027977
IFITM3	0.027695
LAMTOR1	0.027681
DYNLT1	0.027651
UBA52	0.027637
NOP58	0.027584
GPX4	0.027523
REEP5	-0.027358
S100A10	0.027274
IFITM2	0.027172
DSP	-0.027161
SLC31A2	-0.027151
PLOD2	0.027008
UBB	-0.026993
BRIP1	0.026887
UGDH	0.026884
NDUFA3	0.026853
RPL22	0.026814
CD24	-0.026801
SLC25A5	0.026655
IFI6	-0.026620
GPR56	0.026603
JTB	0.026591
STRA13	0.026504
RPLP0	-0.026462
ARMCX6	0.026452
RPS8	0.026451
CFL1	0.026396
CEBPB	0.026319
SCCPDH	-0.026301
PSMA1	0.026295
CD63	0.026081
TMC4	-0.025741
RPS26	0.025682
RAP2C	0.025642
AKR1C2	-0.025553
TFF3	-0.025545
ATP6V0D1	-0.025535
CFB	-0.025381
SDCBP	-0.025216
ECI1	0.025155
DNAJA1	0.025099
FAM214A	-0.025023
S100A8	-0.024885
UQCRH	0.024883
S100A16	-0.024864
C1QBP	0.024736
ABAT	0.024648
MRPS21	-0.024599
TMED10	0.024561
LMNB1	0.024374
HMGB1	0.024351
CDKN3	0.024289
RRM2	0.024252
HNRNPK	0.024239
LAPTM4B	0.024209
HNRNPAB	0.024182
RPL10A	0.024164
DBI	0.024110
NDUFS3	0.024063
BPIFB1	-0.024059
COX6B1	0.023987
EPAS1	-0.023923
NSA2	0.023858
HN1	0.023842
BLVRB	0.023808
ATP6V1F	0.023789
CALM2	0.023762
CEACAM6	-0.023633
SLC7A5	0.023609
OST4	0.023587
ATP5J2	0.023560
ANP32B	0.023499
MRPS23	0.023461
PRR11	0.023410
GPRC5A	-0.023375
VMP1	-0.023226
CCNB1	0.023203
SNRPE	0.023046
PLK2	0.022996
GFRA1	0.022963
DYNLT3	0.022906
TTC3	-0.022880
STARD10	0.022826
TMEM14C	0.022793
PSMB6	0.022767
KYNU	-0.022754
MIR21	-0.022745
SAT1	-0.022729
YPEL5	-0.022707
TRMT112	0.022628
RPS15	0.022556
BOLA3	0.022474
SH3BGRL	-0.022411
RPL36AL	0.022239
SNRPD2	0.022235
RAC1	-0.022228
SLC6A14	0.022176
CCT3	0.022165
KRT80	-0.021914
RPL14	0.021805
SH3YL1	-0.021646
TGFBI	-0.021607
TCEB1	0.021490
IFIT3	0.021469
COX1	0.021391
NDUFB4	0.021391
ANXA9	0.021389
RAB9A	-0.021280
RPL36	0.021278
CNBP	0.021277
COX16	0.021263
SUB1	0.021160
LAP3	0.021094
SLC9A3R1	0.021076
PPIB	0.021065
TIMMDC1	0.021052
COX7B	0.021052
CBX3	0.021049
IGFBP5	-0.021025
FTH1	-0.020997
PNPT1	0.020986
LSM7	0.020957
ACSL3	-0.020874
DDX39A	0.020751
TMEM14A	0.020714
TPM1	0.020701
RPS15A	-0.020654
OAS1	0.020598
PLP2	0.020574
SDC4	-0.020574
ARL6IP1	0.020504
MRPS24	0.020452
RASEF	-0.020417
SNRPB	0.020373
S1PR3	-0.020354
ATRAID	0.020336
MARCKSL1	0.020283
AURKA	0.020205
ENO1	-0.020141
SPINT2	0.019994
CSNK2B	-0.019992
RPL26	0.019926
ZG16B	-0.019868
TMEM14B	0.019838
MLPH	-0.019781
TRIM33	-0.019760
ERMP1	-0.019746
NEDD8	0.019647
BPIFA1	-0.019634
HILPDA	-0.019624
KRTCAP2	0.019585
CENPW	0.019576
PKIB	0.019567
USP32	-0.019538
STAT1	0.019493
ALYREF	0.019386
MGST1	0.019367
ATP5C1	0.019352
CSDE1	-0.019333
DLG5	0.019329
SLC38A6	0.019151
UFD1L	0.019123
PIK3R3	-0.019033
PRKAR1A	-0.019019
SEMA4C	-0.018921
CA12	0.018834
COX5A	0.018801
CMC2	0.018674
NOL11	0.018584
SLC25A3	0.018578
DTX3L	0.018446
FAM213A	0.018415
LASP1	0.018371
RPL4	0.018366
PAICS	0.018340
MUCL1	0.018334
SEPHS2	0.018280
AKR1C1	-0.018278
NTN4	-0.018260
LAMTOR5	0.018162
HPRT1	0.018155
ZFAS1	-0.018122
ATP5A1	0.018069
MDH2	0.018024
CERS2	0.018004
PTPLB	0.017937
GNAS	-0.017933
RPS7	0.017876
RPL7	-0.017846
SCRN1	-0.017811
CDC123	0.017786
NELFCD	0.017766
PRDX5	0.017728
HNRNPC	0.017712
ERP29	0.017606
RPS3A	-0.017604
LINC00052	0.017603
NAA20	0.017494
RACGAP1	0.017473
EIF5	-0.017453
PSMA5	0.017420
YWHAQ	0.017408
RPL23A	-0.017384
NAE1	0.017377
COX3	-0.017374
FIBP	0.017331
NOP10	0.017322
CYB561	0.017249
RPS21	-0.017244
HSPD1	0.017171
HEATR6	-0.017127
POLR2I	0.017100
ITGB6	-0.017082
ATP5G1	0.017055
TMEM167A	0.017046
VKORC1	0.017035
TFPI2	0.016998
ARPP19	0.016899
DDR1	0.016895
C14orf119	0.016890
MEST	0.016888
HIST1H2BK	0.016871
TXNIP	0.016853
ITM2B	0.016837
NUDT19	-0.016832
TSC22D3	-0.016789
RPL8	-0.016772
CACYBP	0.016745
PSMA7	0.016706
CD9	-0.016684
ARL8B	0.016676
PGRMC1	0.016633
CCT7	0.016611
RPF2	0.016594
RAD51C	0.016590
NAA50	0.016584
SNHG19	0.016528
PRMT6	0.016413
PLSCR1	0.016407
SERINC5	-0.016397
TRMT5	0.016377
TMED2	0.016368
NCOA3	-0.016342
SOD1	0.016325
TAX1BP3	-0.016320
CFAP20	0.016291
KCNK6	0.016285
TMBIM4	0.016252
CHCHD3	0.016205
CTBP2	-0.016199
ID1	-0.016187
ATP5G3	0.016178
PSMB5	0.016144
RBBP7	0.016066
POLR2G	0.016044
RPS17	-0.016037
GABBR2	-0.016013
UBE4A	-0.016004
CEBPD	-0.015976
IDH2	0.015918
PGK1	0.015913
DEK	0.015870
TOP2B	-0.015866
PHACTR2	-0.015818
VDAC1	0.015787
USP32P2	-0.015777
POLR2J	0.015763
ILF2	0.015716
TPRKB	0.015683
SKA2	0.015670
ARPC1B	-0.015669
ABCC3	-0.015595
DUT	0.015584
MTHFD1	0.015496
COX4I1	0.015470
MYOF	-0.015446
DKC1	0.015436
TIMP3	-0.015429
IGFBP2	-0.015398
SOX4	-0.015395
COX5B	0.015388
SNHG8	0.015339
SERBP1	0.015329
NCL	0.015300
SLC25A24	0.015242
POP7	0.015144
ATP5H	0.015128
TRIM16	-0.015114
WRB	0.015089
WAC-AS1	-0.015071
OSTC	0.015051
CRABP2	-0.015026
DCTPP1	0.015002
HNRNPA2B1	0.014998
C3orf14	0.014986