!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Halothane
!smiles	C(C(F)(F)F)(Cl)Br
!drugbank_id	DB01159
!pubchem_cid	3562
!cell_type	Whole brain - 5 exposures
!organism	rat
!end_metadata
TTR	-0.428832
NDRG2	0.153205
NNAT	-0.141169
TSPAN3	-0.139344
COX1	-0.135189
HSPA8	0.119911
ACTG1	-0.115137
SLC25A4	0.112414
NDUFB9	0.111471
RPS29	-0.111462
SPOCK2	0.110992
ALDOC	0.109506
PRNP	0.102324
NELL2	0.102036
FTH1	-0.101365
MRFAP1	-0.097801
TUBA1A	-0.096053
ATP1B1	0.092586
SLC25A3	0.091975
ACTB	-0.089291
CNTNAP1	0.088663
NDUFV2	0.087809
CHN1	0.086860
TPT1	-0.083010
CYTB	-0.082930
RPL17	0.082796
CPE	-0.082429
APP	0.081264
COX4I1	0.080888
PSAP	-0.080096
RPL9	0.079428
RPL19	0.077729
COX7A2	0.076072
PTN	-0.075934
RPS27A	0.074993
DYNLL1	0.074676
SLC25A5	0.074439
RPS14	0.074157
RPL31	0.074032
PABPC4	-0.073913
RPS8	0.072862
UQCR11	0.070049
COX2	-0.068753
ND4	-0.068258
SPARCL1	0.067122
BCAT1	-0.064782
INA	0.064399
LDHB	0.064093
EEF1A2	-0.063615
VSNL1	0.063498
GAA	-0.062538
CACNA2D1	0.061235
ND1	-0.060373
APOD	-0.058205
CALB1	0.056345
ENO1	-0.055118
CSRP1	0.054494
CYC1	0.054223
PLP1	-0.053421
RPS9	-0.052867
NDUFA4	0.052316
CKB	0.052191
GFAP	-0.051782
MBP	0.051608
TOM1L2	-0.050985
RPS17	0.050877
ATP5F1	0.050673
HPCA	0.050657
COX5A	0.050515
STMN1	0.050486
TTC3	0.049795
KLF9	0.049491
SYP	0.049463
GLUL	-0.049344
RPL18A	-0.049309
ATP5B	-0.049208
CTSS	0.049084
RPLP2	0.048515
NDUFB6	0.047958
NDUFA3	0.047795
COX7B	0.047440
CPLX1	0.047392
GNAO1	0.047273
NDUFA8	0.046458
CADPS	0.045690
VPS4A	0.045209
MDH1	0.045145
YWHAH	0.044951
UQCRC2	0.044276
RPS16	0.044221
NEUROD1	0.043825
CAMK2B	0.043380
PRKCB	0.043298
VDAC1	-0.042699
GSTM2	-0.042259
RPS13	0.042183
CSPG5	-0.042118
SPTAN1	0.041589
RPS26	0.041439
PPT2	-0.041151
UCHL1	-0.040976
SNAP25	0.040410
MFGE8	-0.040373
KCNC1	0.040099
RPL35	-0.040044
PMEPA1	-0.039892
TAGLN3	0.039811
CHGB	0.039765
HSP90AB1	0.039721
ATP5H	0.039655
GDI1	-0.039583
PJA2	0.039396
CD63	-0.039393
CLTA	0.039330
PTGDS	0.039198
PTP4A1	-0.038916
GABARAP	0.038906
RTN1	0.038688
NDUFC2	0.038192
NFIX	0.037971
FABP6	-0.037944
EIF2B2	-0.037919
BASP1	0.037642
GLUD1	-0.037340
TRAPPC3	-0.036173
PTPRS	-0.035984
HSP90AA1	0.035812
SLC12A5	0.035440
PSMB4	0.035419
FEZ1	0.035012
PVALB	0.034767
NME2	-0.034721
CX3CL1	0.034692
UBR5	-0.034487
UBE2J2	-0.034368
DCTN1	-0.034279
PITPNA	0.034063
RARA	-0.033934
REEP2	-0.033878
DYNC1H1	-0.033802
COX6A1	0.033594
RPL10	0.033584
TUBB	-0.033534
MAL	0.033378
NDRG4	0.033341
RPS15A	0.033262
SLC3A1	-0.033128
FIS1	-0.032987
RPL7A	0.032948
CNBP	0.032723
DTD1	0.032652
ARF1	-0.032564
EIF4A2	0.032541
QDPR	-0.032193
MAP1LC3B	0.031762
WBP4	-0.031413
PPP2R1A	0.031402
ATP2A2	0.031287
AKR1A1	0.031063
RPS21	0.031018
SCN1B	0.030723
COLQ	-0.030717
HMGCS1	-0.030465
CST3	0.030345
GNB1	0.030140
NTSR2	0.030133
CYFIP2	-0.030096
EIF5B	0.029799
ELAVL4	0.029777
SDCBP	0.029578
RPLP0	-0.029551
CFL1	0.029420
RPS5	0.029333
NDUFA9	0.029296
MAPK8IP2	0.029178
PRKAG1	-0.028587
CAMKK1	0.028546
RPL3	0.028522
PTGIR	-0.028506
SYT5	-0.028332
CRYAB	0.028247
RPS25	0.028150
VIM	-0.027702
CSTB	-0.027655
CPLX2	0.027627
ATP1A3	-0.027616
APOE	-0.027615
PGK1	0.027548
VPS45	-0.027529
RPL23	0.027449
LEP	-0.027025
AUH	0.026863
TRAPPC1	0.026744
HSD11B1	0.026734
RPS3	0.026695
LSAMP	0.026679
TMA7	0.026369
SYNJ1	0.026340
NME1	-0.026226
SIRT2	-0.026110
RGS4	0.026107
GAPDH	-0.026042
PPP1CB	0.025719
SLC6A1	0.025666
TUBB2B	-0.025607
CDC42BPB	-0.025557
YWHAZ	-0.025330
CD81	0.025303
MAP1LC3A	-0.025042
DNM1	0.024969
SCG5	-0.024902
SPARC	0.024742
VAMP2	0.024583
NDUFAB1	0.024460
YWHAQ	0.024232
CLTC	0.024230
RAB10	0.024230
ATP5C1	0.024225
CUTA	-0.024171
RPS4Y1	0.024131
ACOT7	-0.024130
MAPK8IP1	0.024125
ND5	-0.023898
ALPL	-0.023864
IL1R2	-0.023739
CCNG1	-0.023689
RPL13A	0.023629
NGFR	-0.023533
RPL18	-0.023477
ND2	0.023473
ATP5J	0.023235
LIN7B	-0.023180
GAD1	-0.023142
GRIK5	0.023131
AP2M1	-0.023088
ATP6V0C	-0.023083
GABRD	0.023069
COX3	-0.022852
SCG3	0.022806
MECR	-0.022779
MATK	-0.022763
MFSD6	0.022755
CALR	-0.022752
NDUFA5	0.022742
ITM2B	0.022622
PRUNE2	0.022515
RESP18	-0.022510
NDUFB4	0.022490
SLC9A1	-0.022478
DDN	-0.022363
KCTD15	-0.022310
VAMP3	0.022260
NPEPPS	0.021914
FAU	0.021906
RPL4	0.021844
CADPS2	0.021839
SOD2	0.021567
ARHGEF9	0.021566
GAS7	0.021539
GJA4	0.021504
SERBP1	0.021442
GRM4	-0.021418
RBBP7	0.021288
PSMB5	0.021226
NDUFB3	0.021174
SNN	0.021077
GNB2	-0.021023
NEDD8	-0.020855
GSTM3	-0.020760
NCAPH2	-0.020740
NXF1	-0.020694
RPL28	0.020641
APBB1	-0.020635
ATP6V1C1	-0.020629
UBALD1	0.020618
PDE1B	-0.020603
C11orf73	0.020534
S100B	0.020519
ATP6V1B2	-0.020434
SDHA	0.020317
NSG1	0.020163
MDH2	0.020147
RPS12	-0.020115
CRP	-0.020087
ZFAND6	-0.020001
PSMD2	0.019991
MATR3	0.019987
ATP6V1F	-0.019985
SNRNP70	-0.019868
PSMC1	-0.019839
DDR1	-0.019831
CXXC5	-0.019796
RAB3A	0.019666
PSAT1	0.019612
ANAPC5	-0.019604
JUP	-0.019559
CAMK2N1	0.019450
HSPD1	0.019448
TUBA4A	0.019446
BNIP3L	0.019393
RPL10A	0.019206
TFRC	-0.019149
OXT	-0.019136
AVP	-0.019070
BIN1	-0.019051
DLK1	-0.019029
RRAGA	-0.018915
FKBP2	-0.018892
ACAT2	-0.018803
SYT11	-0.018802
SQSTM1	-0.018799
GUCY1B3	0.018777
NELL1	0.018770
GATM	-0.018675
ADCY2	0.018630
NRCAM	0.018579
STK10	-0.018557
GNB2L1	-0.018484
ATP2A3	0.018478
STX1B	0.018350
RPL37	0.018238
RPL5	0.018222
PPIA	-0.018213
VPS29	0.018183
STX1A	-0.018111
SGTA	-0.018042
RPL15	-0.018020
FASN	-0.017983
RABGGTB	0.017974
DYNLRB1	-0.017892
PKM	0.017848
ALDOA	0.017847
SLC25A17	-0.017738
GABRA6	0.017673
RPS11	0.017620
RNF4	0.017598
SLC4A4	0.017556
RPL8	0.017369
SLC27A1	-0.017247
NUP107	-0.017196
TMBIM6	-0.017158
FDXR	-0.017153
CLCN3	0.017130
AGRN	-0.017089
PCP4	0.017087
WSB2	0.016901
PFKM	0.016845
SLC22A5	0.016829
CSNK2B	-0.016765
RAB6A	-0.016730
PGAM1	0.016699
SVOP	-0.016642
IGFBP2	-0.016551
CYCS	0.016501
OAZ1	0.016451
HADHA	-0.016308
PTP4A2	0.016263
SLC6A15	0.016249
H2AFZ	0.016137
BLVRA	-0.016045
ID2	-0.015988
NDUFC1	0.015972
IDH3G	0.015967
GDE1	0.015897
CHGA	-0.015840
KLHDC3	0.015829
NCKAP1	0.015823
MYL9	0.015820
BTG1	0.015791
VAMP1	-0.015766
MTDH	0.015764
AZI2	-0.015709
PRDX6	-0.015603
MAFK	-0.015574
GALM	-0.015567
PPP3CA	-0.015563
CPSF4	-0.015476
ATP6V1A	0.015447
DNAJA2	0.015435
SOD1	-0.015407
GNAI2	-0.015391
ATP6V0A1	-0.015387
FKBP1A	0.015369
GRIN2A	-0.015329
SLC6A8	-0.015292
TMEM47	0.015208
RPL11	0.015107
DYNC1I1	-0.015096
CSDE1	0.015081
YBX1	0.015022
MGST3	-0.014958
SLC14A2	-0.014882
PPP1CA	-0.014875
FN3K	-0.014834
CACNA1B	-0.014801
TMEM255B	-0.014740
HAGH	-0.014734
ACP2	-0.014703
DBN1	-0.014668
PDK2	0.014656
ECHS1	-0.014641
SPINT2	-0.014632
PCOLCE	-0.014612
MAPKAPK2	-0.014589
MYL12A	0.014514
ALAS2	-0.014502
MED25	-0.014480
ARL4A	-0.014450
NDUFB11	0.014404
SDC4	-0.014400
NDUFB2	-0.014397
PPP2R2B	-0.014378
TCF4	0.014354
RPL27	-0.014335
MYLK2	0.014333
SUB1	0.014316
GPX1	-0.014311
SMIM12	-0.014305
FBLIM1	-0.014299
HIGD2A	0.014190
GMFB	-0.014176
TMED10	-0.014111
CAPNS1	0.014087
CSNK1D	-0.014083
MVD	-0.014046
PPP3R1	-0.013974
CD200	-0.013967
GRK4	-0.013966
PHGDH	-0.013963
SLC8A2	-0.013951
SCG2	0.013910
PHB2	0.013880
CSN3	0.013822
DPP6	-0.013792
ATP5A1	-0.013770
RBP4	0.013741
CAP2	0.013729
PACS1	-0.013680
TRRAP	-0.013658
SCARB1	-0.013657
COX4I2	-0.013645
NR1H2	-0.013623
ABCD3	-0.013583
ARF6	-0.013554
TSPAN17	0.013454
HAX1	0.013421
PAIP1	0.013415
H1F0	0.013409
SLC6A11	-0.013402
PPP2CB	0.013398
CYTH2	-0.013391
UNC119	-0.013389
SPTBN2	-0.013386
GDA	-0.013350
CAMK2N2	0.013340
HMGCS2	0.013317
GPHN	-0.013315
SNCA	0.013291
GNA15	-0.013256
KCNC4	0.013234
MYCBP2	0.013227
EID1	-0.013192
SLC25A14	0.013184
VGF	-0.013183
GRB14	0.013168
RPL14	-0.013156
RPS6	0.013150
CSNK1G2	-0.013038
RASGRF1	0.012995
LTA4H	-0.012983
TH	-0.012946
SLC13A2	-0.012930
ACSL3	0.012921
CSDC2	-0.012910
IGF2R	0.012899
FAM83F	-0.012889
LITAF	-0.012875
FAM160B1	-0.012853
SIGMAR1	-0.012825
HYAL2	-0.012786
RASA2	-0.012785
ADRBK1	-0.012774
TPI1	-0.012734
PDHA1	0.012722
EIF4H	0.012679
HRAS	0.012675
CBX1	0.012658
RASGRP1	0.012647
SLC6A9	-0.012638
PSMD4	0.012619
DDT	0.012593
NCDN	0.012577
SNRPN	-0.012550
RALGDS	-0.012537
ECH1	0.012521
HSPB1	-0.012475
RPS23	0.012460
CNP	-0.012452
A2M	-0.012440
GRIA2	0.012436