!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Etanercept
!drugbank_id	DB00005
!cell_type	whole-blood leukocytes
!organism	human
!end_metadata
DNAAF1	-0.122312
GPR84	-0.069215
HBD	0.065857
OLR1	-0.063162
FGFBP2	0.058188
KLRB1	0.057697
EMR1	-0.056960
HLA-DRB5	-0.056233
PSTPIP2	-0.054906
GZMA	0.054617
TIFA	-0.054503
NBN	-0.053866
IRAK2	-0.053683
CLIC4	-0.053416
PAM	-0.052404
GZMH	0.052242
GBP5	-0.049786
CLEC4D	-0.049042
CHST13	0.048847
TFF3	-0.048717
GBP1	-0.048448
MARCH3	-0.048352
DCUN1D3	-0.046471
GBP1P1	-0.046309
MYOM2	0.046280
KRT23	-0.046245
CEACAM1	-0.045178
NDUFV2	-0.044559
VILL	-0.044547
C15orf48	-0.044363
IRAK3	-0.043749
SLC39A8	-0.043689
DRAM1	-0.043563
EOMES	0.043458
PRDM8	-0.043350
SLC11A2	-0.043298
RAB20	-0.042665
C1orf85	0.041835
PI3	-0.041807
HLA-A	-0.041536
GK	-0.041411
SAMSN1	-0.041336
ALDH2	-0.041327
NKG7	0.041307
HP	-0.041279
STOM	-0.041144
CFD	-0.041113
UGCG	-0.041030
CISH	-0.040606
GCH1	-0.040447
CTSH	-0.039978
NLRP3	-0.039698
PIK3AP1	-0.039285
RIPK2	-0.039238
HLA-DRB1	-0.039230
HIVEP1	-0.039068
ORM1	-0.038694
IL2RB	0.038659
BATF3	-0.038433
CLIC3	0.038431
MARCKS	-0.038348
RELB	-0.038206
TNFAIP2	-0.037924
AKR1C3	0.037478
PLAU	-0.037405
S1PR5	0.037383
CCM2L	-0.037216
TTL	-0.037149
AHSP	0.036868
CRIP1	0.036864
NFKB1	-0.036802
LDHA	-0.036751
PRF1	0.036555
TNIP1	-0.036281
BATF	-0.036154
ADORA2A	-0.036114
TCF7L2	-0.035491
TESK2	-0.035436
CD274	-0.034906
CCL20	-0.034740
GYG1	-0.034718
CCL2	0.034610
SH2D3A	-0.034592
FSCN1	-0.034485
GPR56	0.034427
FCER1G	-0.034249
SERPINB1	-0.034039
BAZ1A	-0.033925
GNLY	0.033918
CLEC4C	0.033865
GRINA	-0.033812
IL1RN	-0.033629
IKBKE	-0.033600
SLC4A1	0.033579
KLRF1	0.033543
CARD17	-0.033509
PFKFB3	-0.033387
DEFA4	0.033243
NFKB2	-0.033227
NFXL1	0.033208
NLRC4	-0.033089
PGLYRP1	-0.033018
LPCAT2	-0.032874
GALC	-0.032856
RELA	-0.032798
PLSCR1	-0.032739
C4BPA	0.032300
VAV1	-0.032145
DENND5A	-0.032103
KYNU	-0.032055
PLEKHF1	0.031894
GCAT	0.031800
SGPP2	-0.031788
SLPI	-0.031699
KRT1	0.031615
ECE1	-0.031550
GZMM	0.031301
ETS2	-0.031245
CCL8	0.031061
ZNF683	0.030904
OXSR1	-0.030720
CD83	-0.030706
DEFA1B	0.030577
CCL23	-0.030509
FKBP5	-0.030270
CTSG	0.030268
RAB21	-0.030204
GBP2	-0.030196
SPIB	-0.030164
NFE2L2	-0.030127
CBX7	0.030104
IFIH1	-0.029969
CD247	0.029921
RILPL2	-0.029861
HLX	-0.029642
PTAFR	-0.029616
OLIG1	-0.029499
DEFA3	0.029452
PDSS1	-0.029328
SUSD3	-0.029287
ADAT1	-0.029222
BATF2	-0.029219
MCEMP1	-0.029162
SFRP1	-0.029039
MTF1	-0.029004
RPL21	0.028963
UPB1	-0.028755
MIIP	-0.028740
DMXL2	-0.028667
GPR141	-0.028666
SRP54	-0.028544
FTH1	-0.028515
TDRD9	-0.028327
SORT1	-0.028282
SOD2	-0.028258
CYBRD1	0.028242
TLE3	-0.028113
RPS15A	0.028080
ORM2	-0.028072
REPS2	-0.027936
EHD1	-0.027904
STAT5A	-0.027833
RSBN1L	0.027817
TRAFD1	-0.027779
FLOT1	-0.027756
FCGR1A	-0.027743
EVA1B	-0.027737
STEAP4	-0.027718
CAMKK2	-0.027716
RPL13A	0.027641
DNAJA1	-0.027641
CHST12	0.027412
ANXA3	-0.027365
CRIP2	0.027352
SLC35B2	-0.027344
PTPN4	0.027324
MVD	-0.027318
TICAM1	-0.027261
GBP4	-0.027199
LACTB	-0.027193
THBS1	-0.027171
C21orf91	-0.027133
SMG5	0.027112
ZNF641	-0.027083
RNF19B	-0.027062
LPCAT1	-0.026979
CD6	0.026826
HCAR2	-0.026816
GRAMD1A	-0.026748
CD3G	0.026701
RNASE2	-0.026663
TGFBR3	0.026652
C3AR1	-0.026587
SMG9	-0.026485
SDCBP	-0.026376
ITCH-IT1	-0.026367
S100A12	-0.026346
DUSP3	-0.026282
PECR	-0.026216
BAG3	0.026191
PKM	-0.026054
RPL31	0.026054
CD58	-0.026039
PLEK	-0.026021
SBNO2	-0.025922
LIMK2	-0.025878
EPM2AIP1	-0.025877
ANAPC13	0.025827
MIR181A2HG	0.025698
CYBB	-0.025682
CYSTM1	-0.025669
CKAP4	-0.025646
HTRA2	-0.025624
FERMT3	-0.025581
ZHX2	-0.025537
PLBD1	-0.025479
SAMD3	0.025479
ACTR3	-0.025465
MYL4	0.025461
TYMP	-0.025427
PCTP	-0.025414
CD82	-0.025352
ITGA5	0.025326
SRXN1	0.025323
ANKRD22	-0.025268
MMP9	-0.025248
IKBIP	0.025172
DEFA1	0.025100
GZMK	0.025082
RPL13AP6	0.025079
ACOX2	-0.025076
COL9A2	-0.025063
DUSP5	-0.025017
SPINT2	-0.024991
MIAT	0.024987
RNF144B	-0.024943
DNLZ	0.024919
PXYLP1	-0.024878
ADA	0.024829
FURIN	-0.024823
RNF165	0.024672
SLC51A	-0.024635
IRF5	-0.024614
FFAR2	-0.024598
SH3GLB1	-0.024581
ARL17A	0.024570
LGALS1	-0.024537
SLC7A5	-0.024340
ATG7	-0.024253
FAS	-0.024166
HCK	-0.024157
TRIB1	-0.024144
HBZ	0.024143
EBI3	-0.024082
ZYG11B	0.024009
TRAF3	-0.023928
LRRC6	0.023926
TAP1	-0.023917
BPI	-0.023867
CHURC1	0.023839
SH2D1B	0.023810
TMEM79	0.023802
FGD4	-0.023769
LAX1	0.023667
FAM188A	-0.023666
TOM1	-0.023661
ANKRD55	-0.023652
DNAJA4	0.023634
TFRC	-0.023589
TMEM42	0.023586
SERPINA1	-0.023549
UBR4	-0.023523
SERPINB8	-0.023510
SPPL2A	-0.023497
SLC15A3	-0.023491
HSPA1A	-0.023467
CLC	-0.023430
OLAH	-0.023427
RAB5A	-0.023394
GP9	-0.023393
SEC22B	-0.023332
IFI16	-0.023227
RPS14	0.023196
FTH1P3	-0.023172
PRPSAP1	-0.023103
IDO1	-0.023046
CENPV	0.023039
RGS1	0.023009
IL7R	0.022988
HIF1A	-0.022916
PTGES	-0.022905
STAT1	-0.022898
TSG101	-0.022896
RPL26	0.022873
DUSP16	-0.022857
CD7	0.022827
SYT11	0.022800
ZNF431	0.022780
NR1H2	-0.022759
PHOSPHO1	0.022757
CD8A	0.022622
HBG1	0.022594
ITK	0.022581
GLRX	-0.022544
GABARAPL2	-0.022539
MOSPD3	-0.022516
CRADD	0.022507
LEPROTL1	0.022497
KIAA1324	0.022466
MAP3K11	-0.022413
RSL24D1	0.022372
NENF	0.022288
HBG2	0.022258
CARHSP1	0.022253
ADAM8	-0.022243
ETV7	-0.022241
IVNS1ABP	-0.022210
SQRDL	-0.022203
IER5	-0.022184
B4GALT5	-0.022168
CPEB4	-0.022081
UPP1	-0.022033
LAMTOR4	0.022032
EXOSC4	-0.021946
CD96	0.021935
PGD	-0.021902
PLA2G7	-0.021894
RNF24	-0.021844
RAB29	-0.021833
RETN	-0.021789
IGSF6	-0.021780
EHD4	-0.021767
RALB	-0.021765
CLDND2	0.021709
CMTM8	0.021707
PIGV	-0.021687
SF3A3	0.021602
MAD2L2	-0.021582
CD160	0.021554
CD40	-0.021552
TBK1	-0.021546
PADI4	-0.021513
HLA-H	-0.021475
HIST3H2A	0.021380
NPRL2	0.021380
S100P	-0.021374
ZC3H12A	-0.021372
LPIN1	0.021362
LHFPL2	-0.021326
CHD4	-0.021306
SLK	-0.021304
MGRN1	-0.021216
ANKRD13A	-0.021191
C12orf10	0.021162
TMEM180	-0.021140
DDIT4	0.021125
LINC00936	0.021124
BCL3	-0.021104
PYHIN1	0.021103
PRRC2A	-0.021085
TBC1D4	0.021082
TUBB1	-0.021073
TP53I3	-0.021039
CLEC4E	-0.021017
GPR108	-0.021003
NECAP2	-0.020991
HSDL1	-0.020969
NOD2	-0.020957
RGL4	-0.020932
F13A1	-0.020920
UBE2E1	-0.020892
N4BP1	-0.020842
F2RL1	0.020818
MGME1	0.020813
MEFV	-0.020811
PTPRCAP	0.020796
RPL10A	0.020783
PLEKHG3	0.020774
GYPB	0.020760
TSEN54	0.020727
RGCC	0.020698
IFNG	0.020687
NRGN	-0.020682
PLXDC2	-0.020679
STXBP2	-0.020665
SPRYD3	0.020657
ARPC3	-0.020656
SEMA6A	-0.020652
P2RY8	0.020646
TCFL5	-0.020641
ZFP36L2	0.020630
TMEM181	0.020600
LY6E	0.020534
GNA15	-0.020520
SIPA1L2	-0.020512
RPA4	-0.020486
FAM107B	-0.020468
TMEM14A	0.020400
CASP5	-0.020384
LMNB1	-0.020365
XBP1	-0.020304
HAMP	-0.020297
RPL12	0.020286
RPH3AL	-0.020274
TAPBP	-0.020271
PLCD1	-0.020267
NCF1	-0.020250
COPS3	0.020249
SCGB3A1	0.020243
GFOD1	0.020233
EIF1AY	0.020229
PITHD1	0.020210
DHRSX	-0.020205
PFKFB2	-0.020181
SRBD1	-0.020149
RPS26P11	0.020148
ASCL2	0.020136
GPER1	-0.020127
ESPN	0.020101
SIN3A	-0.020098
GMPR	0.020094
NINJ2	0.020084
KANK2	0.020072
PGS1	-0.020068
HK3	-0.020065
CHMP4B	-0.020056
ABHD3	0.020036
ARHGDIA	-0.020025
STARD10	-0.020023
MYD88	-0.020011
SLU7	-0.020002
RAP2C	-0.019976
DGKQ	0.019947
TMEM120A	-0.019943
RAB40C	0.019913
DDX58	-0.019899
PADI2	-0.019893
LAG3	0.019888
TSC22D4	-0.019884
HDAC2	-0.019799
SRSF7	0.019792
GNB1	-0.019733
SH2D1A	0.019720
SRPK1	-0.019691
GPR162	0.019669
IL18R1	-0.019641
REM2	0.019637
FKBP1A	-0.019631
WSB1	-0.019629
STRADB	0.019623
SPECC1L	-0.019616
IRF9	-0.019610
MFGE8	0.019601
RHD	0.019595
DPCD	0.019551
VCAN	-0.019517
ANKRD12	-0.019516
PFDN5	0.019504
OSCAR	-0.019501
RIN3	-0.019439
KLRD1	0.019428
HDGF	-0.019410
SLC1A3	-0.019384
MAP3K8	-0.019383
GNG5	-0.019369
SEC23B	-0.019329
ACSL1	-0.019298
RPL27	0.019298
SIGLEC9	-0.019283
ARHGAP19	0.019279
GPR97	-0.019261
AQP9	-0.019256
CDC42EP2	-0.019226
OGFRL1	0.019222
NCALD	0.019200
CMPK1	0.019169
NUMB	-0.019165
ST3GAL2	-0.019152
CHST7	0.019146
HBP1	-0.019128
RAP2A	0.019118
VOPP1	-0.019114
STARD8	-0.019106
SLC30A7	-0.019084
CD44	-0.019060
P2RY13	-0.019051
DNMT1	0.019016
NFKBIB	-0.019012
REXO2	0.019009
OAT	-0.019004
POR	-0.018962
PARP14	-0.018958
SLFN13	0.018947
ATP6AP1	-0.018935
AHSA1	0.018933
HADH	0.018922
HDDC2	0.018906
IDI1	-0.018904
ARID3B	0.018893
NMI	-0.018865