!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 30 Hour
!organism	rat
!end_metadata
ATP2A1	0.294973
H19	0.190551
PABPC4	0.184016
TCAP	0.161738
TNNI2	0.158438
SLC25A4	0.155709
TNNC2	0.153495
RPLP0	0.149704
CKMT2	0.148913
PKM	0.146070
ACTN2	0.140087
CA3	0.139545
MDH1	0.131798
ASB2	-0.118175
RPS14	0.114314
UBC	-0.107744
MYH7	0.107159
MGST3	0.105667
MYH2	0.100060
MYL2	0.096807
CRYAB	0.096481
TUBA4A	-0.094531
MYLPF	0.092976
ANKRD1	0.090304
MDH2	0.088413
MYL1	0.088206
FABP3	0.087939
CST3	0.087320
COX3	0.086682
RPS16	0.085507
EIF4A2	0.085496
ACADM	0.084693
GAPDH	0.082788
RPS8	0.080893
MYH1	0.078111
MYH6	0.078099
ALDOA	0.075838
MYBPC1	0.075595
CCNG1	0.074572
SEPW1	-0.073048
NDUFB9	-0.071416
PSAP	0.071280
UQCRFS1	0.071124
TNNI1	0.069913
RPL7A	0.068872
RPL17	0.068031
COL1A1	0.067489
CAPZA2	-0.066796
RPL19	-0.065081
COX6A2	0.063686
MYBPH	-0.063644
ASPH	-0.063417
COX4I1	0.062023
ITGB1	0.061796
COX7A2	-0.061396
PPP1CB	0.061205
RPS9	0.061040
CSRP3	0.057704
ENO3	0.056759
ACTG1	-0.056285
ND2	0.056181
HADHB	0.056054
MRFAP1	-0.055793
RPL31	0.055089
TECR	-0.054636
RPS3	0.054481
RPL10	0.054298
THBS4	0.054144
ALDH1A1	-0.053629
MPC1	-0.052281
DES	0.052090
CYC1	-0.051966
SLC25A3	-0.051678
NPHP1	-0.051524
ND5	-0.051416
AK1	-0.051352
LYZ	0.051058
MYL3	0.051058
HSPA8	-0.050922
DBP	0.050474
COX2	-0.050374
TMBIM6	-0.050369
RPS17	0.050119
IDH2	0.049386
NDUFV2	0.048922
RPS23	0.048225
GNAS	0.048027
NDUFA4	-0.047421
BIN1	0.047386
RPLP2	0.047218
CACNA2D1	-0.047152
RPL37	0.047110
RPL6	0.046626
TMA7	-0.046338
SVIL	0.046207
RPS15A	0.045008
NDRG2	0.044862
PDHA1	0.044824
FTH1	0.044772
ECHS1	-0.044299
UQCR11	0.044140
B2M	0.043949
TPI1	0.043761
SEPP1	0.043745
EEF1G	-0.043408
IGFBP6	0.042769
RPS27A	0.042736
GPX3	0.042730
GPD1	-0.042484
VCP	0.042384
APOE	0.041892
ARF1	-0.041446
NDUFA5	0.041374
KLHL41	0.041126
VIM	0.041061
ACTC1	0.040809
ZFAND6	-0.040798
RPL18A	0.040767
DBI	0.040630
COL3A1	-0.040325
ACSL6	-0.040316
GOT2	0.040133
RPS4Y1	0.039906
COX1	0.039696
FAU	0.039443
RPS10	0.038623
HSPB6	0.038375
PKIA	-0.038286
GOT1	0.038153
NDUFB8	-0.037966
ATP5O	0.037821
JPH2	-0.037263
PHKA1	-0.037161
CD36	0.036836
SLC37A4	-0.036263
RPS12	-0.035896
RRAD	0.035879
CKM	0.035800
PAICS	-0.035633
CPT2	0.035382
GSTP1	-0.035064
RPL9	0.034881
TUBA1B	-0.034792
TXN2	-0.034724
CPE	-0.034715
CNBP	0.034567
PRNP	-0.034528
GNB2L1	0.034399
DCAF6	0.034064
KCNJ11	-0.033697
SDHA	-0.033379
KLF9	0.033272
LPL	0.032740
HSP90AB1	-0.032644
HIBADH	0.032286
ND4	0.031871
BTG2	-0.031764
ATP2A2	0.031442
COX5A	0.031122
IFITM3	0.031117
CLU	-0.030869
GPX4	0.030223
RPL4	0.030090
GAA	0.029998
TCEB1	-0.029867
JUN	-0.029542
NDUFC2	-0.029400
ATP1A2	0.029383
DHRS7C	-0.029025
PGM2	-0.028995
ETFA	0.028508
NACA	0.028447
NME2	0.028381
YWHAG	-0.028362
PSMD2	0.027851
NEU2	-0.027767
OAZ1	-0.027700
RPS21	0.027661
FABP6	-0.027638
LUM	-0.027580
ECH1	0.027214
RPL24	-0.027171
BSG	0.027159
PTP4A2	0.027041
RPL39	0.027023
NDUFA8	0.026951
CPT1B	0.026741
NEXN	-0.026674
ACAT1	-0.026667
TUFM	0.026491
LDB3	-0.026048
RPL26	0.025938
TIMM23	-0.025929
COX7B	0.025847
AMPD1	-0.025804
ITM2B	0.025760
PPP1R1A	0.025646
DCN	0.025507
ATP1B1	0.024728
NOL3	0.024464
MAP1LC3A	0.024377
PHKG1	-0.024335
GABARAPL2	-0.024281
NCL	0.024193
KCNC4	-0.023919
UCP3	-0.023640
RPS25	0.023588
GLUL	0.023329
NEK7	-0.023206
COL1A2	-0.023152
XDH	0.023100
RPL10A	0.023006
TOMM6	-0.022936
APP	0.022723
YBX3	0.022693
PADI2	-0.022677
PSMB1	0.022656
RPL28	0.022509
CDKN1A	0.022479
H2AFZ	-0.022432
ACAA2	0.022242
TSPAN3	-0.022116
NEDD8	-0.022033
FMOD	0.021925
MYLK2	-0.021890
ATP5B	0.021822
CUTA	-0.021706
TIMP2	0.021559
PFN1	0.021549
HDLBP	0.021414
SIRT2	-0.021385
NDUFC1	-0.021370
TNNT3	-0.021299
YBX1	0.021259
CTSD	0.021191
RPL36AL	0.021124
RPS26	0.021105
GSTA5	-0.021061
FOS	-0.021053
CD151	0.020967
ATP5A1	0.020963
SLC41A3	-0.020824
HSPE1	0.020452
RPS5	0.020365
PARK7	-0.020358
ACTB	0.020345
RPL23	0.020290
PMEPA1	0.020261
PAIP1	-0.020193
DYNLL1	0.020186
PDLIM1	-0.020030
GPD2	-0.019982
CAPN2	0.019794
ATP5G1	-0.019647
BCAT2	-0.019593
GSTM1	-0.019516
HSPB1	-0.019497
PSMD11	0.019381
PRDX1	0.019378
PPP3R1	-0.018949
ADK	-0.018927
CD63	-0.018893
TUBA1A	-0.018893
PTOV1	-0.018873
ACTA1	0.018859
UCP2	0.018856
ACADVL	0.018840
ATP6V1F	-0.018756
NDUFB2	0.018724
RPS7	0.018671
ADCY2	-0.018541
RAB6A	-0.018480
ENO1	-0.018427
SLC25A5	0.018302
CTSS	0.018238
TXNIP	0.018190
NEB	0.018140
PYGM	0.018086
AP2M1	-0.017861
SYNGR2	-0.017747
CACNG1	-0.017742
RPL12	0.017725
SPARC	0.017687
RPL13A	-0.017672
NDUFB3	-0.017646
P4HA1	-0.017591
LDHB	-0.017518
CD81	-0.017504
SCN1B	-0.017460
CHAD	0.017344
ATP1B3	-0.017294
RAB5B	-0.017219
CLTA	-0.017195
HGS	0.017158
HSD11B1	-0.017114
CTSV	0.016943
FCGRT	0.016936
HADHA	0.016833
FXYD1	-0.016762
CACNA1S	-0.016743
EIF3D	-0.016641
NPEPPS	0.016620
NR1D1	-0.016605
MYL12B	0.016497
CAPNS1	0.016494
IL15	0.016431
ATP1B2	-0.016298
MORF4L2	0.016295
PRKACA	-0.016267
TNKS2	-0.016243
COPS7A	-0.016184
ETFDH	0.016059
S100A10	0.016008
ALAS1	0.015952
TSC22D1	0.015928
ATP5G2	-0.015827
RPL3	0.015711
ECI1	0.015608
CYTB	-0.015554
RPL15	0.015529
VEZF1	-0.015472
CHRNB1	-0.015421
UBE2J2	0.015389
VDAC1	0.015353
PITPNA	-0.015167
IRF7	0.015030
LIMS1	0.014973
GSTO1	0.014958
NUCB1	-0.014906
RPL27	-0.014896
MPST	-0.014886
DLST	0.014880
TUBB4B	-0.014775
LAMC1	-0.014742
SPRY1	-0.014705
RAB12	0.014562
MAPKAPK2	-0.014555
PDK2	0.014390
ALDH6A1	-0.014377
KLHDC3	0.014372
CALU	-0.014364
GRN	0.014321
GRB10	-0.014215
C1QB	0.014114
CYHR1	-0.014112
AQP1	-0.014110
SLC28A2	0.014034
ACTA2	0.013876
ATP6	-0.013829
TCN2	0.013765
YWHAH	0.013654
BTG1	0.013606
HIGD2A	0.013589
ATF3	-0.013578
NDUFS7	0.013553
TUBB	-0.013485
MLLT3	-0.013482
PJA2	0.013430
MYOC	0.013426
YWHAB	-0.013389
MAPK6	-0.013364
RAB28	-0.013341
HNRNPAB	0.013325
RAF1	-0.013280
EID1	-0.013279
PFKM	-0.013253
PPP2R1A	-0.013130
SOD2	-0.013123
PRKAR1A	-0.013110
MARC2	0.013094
RPL35	0.013052
LOXL1	0.012956
PPP6C	-0.012929
DECR1	0.012852
PER2	0.012841
ACOX1	0.012771
BCLAF1	-0.012694
ME1	-0.012669
ANAPC5	-0.012663
ND1	0.012651
DNAJB5	-0.012622
ANXA6	-0.012544
JTB	0.012539
ARPC5L	-0.012521
TIMM17A	-0.012519
PRDX6	-0.012518
PDP1	0.012396
PPP2CB	0.012341
NDUFA9	-0.012302
ULK2	-0.012296
COX4I2	-0.012213
PSMA7	0.012176
CASQ2	0.012154
RHOA	0.012068
GTF2A2	-0.011985
MMP14	-0.011960
SQSTM1	-0.011914
PSMD1	0.011888
GRHPR	-0.011862
PSMA4	0.011834
NRBP1	-0.011826
HSPD1	-0.011749
CDC42EP3	-0.011745
NAPA	-0.011740
FKBP1A	-0.011716
TMEM126B	-0.011707
DARS	0.011681
LAMTOR1	-0.011601
LOX	0.011595
AGTPBP1	-0.011588
CD1D	-0.011579
MYOD1	0.011555
GNG5	-0.011541
MYOG	0.011537
CTBP1	-0.011520
COL5A2	0.011519
PCYT2	0.011491
FAM160B2	-0.011267
HSPA9	-0.011267
CGRRF1	-0.011185
HIGD1A	-0.011177
EGR1	-0.011176
IGF2	-0.011168
PPIA	-0.011140
CAPN1	-0.011099
PDIA6	-0.011097
KCTD15	-0.011095
PSMB6	-0.011032
EEF2	0.010983
ATP5F1	0.010962
SSR3	-0.010933
SLC25A11	-0.010903
AKR1A1	0.010901
NENF	-0.010899
UBQLN1	-0.010876
DDX50	0.010873
GPX1	0.010862
POSTN	0.010808
NUDT4	-0.010773
MFGE8	0.010753
RPL21	0.010741
TMEM255B	-0.010692
OAT	0.010684
ATP5D	-0.010624
DAPK2	-0.010590
GSTM2	0.010567
ATP6V0C	0.010549
COL15A1	-0.010535
GNAI2	-0.010517
DLAT	0.010504
RPS11	-0.010495
GRB14	0.010479
RAB10	-0.010427
C11orf73	-0.010344
PSMC5	0.010326
EMP1	-0.010317
NFYC	-0.010290
TMEM59	-0.010269
KLF4	-0.010229
YWHAE	-0.010186
LAMP1	0.010164
ANXA5	-0.010140
APH1A	-0.010110
PSMB2	0.010104
SNRPN	-0.010076
SLC25A30	0.010066
CHURC1	-0.010039
POLR2F	-0.010028
ADH5	-0.009960
TMOD1	-0.009930
SHFM1	0.009859
CAPN3	-0.009848
ACO1	0.009799
FIS1	-0.009740
LEP	-0.009732
SERPINH1	-0.009709
RGCC	0.009637
PHB2	0.009635
HRAS	-0.009620
PLAA	0.009586
PSMA2	0.009543
TAF10	0.009535
PPP2CA	0.009521
MTDH	0.009497
PGK1	-0.009445
EIF4E	-0.009422
DNAJA1	-0.009414
PLEKHA1	0.009404
GIPC1	-0.009401
CTSC	0.009344
MAP1LC3B	0.009334
PNRC2	-0.009318
TMED2	0.009304
MTCH2	0.009298
TPT1	-0.009295
RCHY1	-0.009292
CYB5A	-0.009287
HNRNPF	0.009262
CDC37	0.009231
CCT3	0.009178