!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Vincristine
!smiles	CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
!drugbank_id	DB00541
!pubchem_cid	5978
!cell_type	SKOV3
!organism	human
!end_metadata
MT2A	0.224249
ALDH1A1	-0.147474
AKR1B1	-0.134952
ID1	-0.131138
MT1X	0.121151
TUBA1A	0.117575
MT1H	0.116633
HSPA8	0.111100
S100A2	-0.110149
HLA-A	0.109821
TUBB4B	0.107050
EEF2	0.106373
MT1HL1	0.104021
DDIT4	-0.103265
SNHG1	-0.098860
ND2	-0.097323
TMSB10	0.097286
IFITM2	0.096424
LGALS1	0.094452
GPX1	0.094053
AKR1C3	-0.091774
HLA-C	0.087200
NNMT	0.086359
PSAT1	-0.086013
TNFRSF12A	-0.082749
IFITM3	0.082665
TUBB3	0.081504
SPCS1	0.078599
RPL29	0.078552
HLA-B	0.076484
PTTG1IP	0.075325
COX2	-0.075092
KRT18	0.073003
GTF3C6	-0.072521
RAN	-0.070790
ACTG1	0.070730
TPT1	0.069934
RPL36	0.067562
RPL7A	0.065849
GADD45A	-0.065654
PABPC3	0.065172
DHRS2	-0.065019
SRP14	0.064000
HMGN3	-0.063464
FTL	-0.061064
IARS	-0.060963
XPOT	-0.060223
RPS26	0.059910
CD24	0.058637
C19orf33	0.058532
ABCB1	0.058391
B2M	0.057649
CAV1	0.055814
MYL6	0.055507
RPS9	0.055395
ZCRB1	-0.055105
SNRPD2	0.054758
RPL35	0.054139
TPI1	0.054116
CTSB	0.053207
PRSS3	-0.052915
OAZ1	0.052013
ASNS	-0.051966
AMIGO2	0.051450
NDUFAB1	-0.050834
TMEM258	0.050237
ACTB	0.050124
TMBIM4	-0.049891
FN1	0.049735
GARS	-0.049545
EDIL3	0.048313
HSPA9	-0.048025
CD63	0.047986
RPL12	0.047625
EIF1	-0.047366
HSP90AB1	-0.047332
RPL14	0.046699
ATF4	-0.046543
NDUFA13	0.046352
FTH1P5	0.046050
HN1	-0.045836
EIF2S2	-0.045757
PFN1	-0.045212
SDCBP	0.044938
CKS1B	-0.044033
CAPNS1	0.044030
UBA52	0.043640
NPM1	-0.043473
RPL8	0.043460
RPL36A	0.043408
HSP90AA1	-0.043062
TBCA	0.042312
EEF1D	0.042144
VCAN	0.042051
RPS5	0.042028
DYNLL1	0.041782
PLP2	0.041542
GGCT	-0.041512
COX6B1	0.041342
PSMB3	-0.041108
S100A10	-0.040863
LDHA	0.040234
PGAM1	-0.040109
RPSA	0.040066
RPS21	0.039891
PRDX1	-0.039815
ZFAS1	-0.039506
RPL32	0.039437
TIMP2	0.039415
ODC1	-0.039403
VIM	0.039059
PRSS23	0.039020
KRT8	0.038670
DDX21	-0.038639
FAM127A	0.038310
UQCRC1	0.038285
SLC38A2	-0.038272
NDUFA12	0.038010
TUBB2A	0.037954
RPL41	0.037940
ANXA4	0.037844
RPS15	0.037830
MAPK6	-0.037799
POLR2L	0.037798
TRIB3	-0.037774
EFEMP1	0.037666
QARS	0.037632
KANSL2	-0.037588
CLTA	0.037509
ITM2B	0.037468
PSMA1	-0.037425
PKM	0.037048
EDF1	0.036997
DYNLT1	-0.036900
RPL13	0.036830
RPS20	0.036697
HSPB1	0.036549
RHOA	0.036212
CFL1	0.036098
FXYD5	0.035917
RPL28	0.035854
ID3	-0.035587
TMBIM6	-0.035500
PRDX2	0.035391
ATP5F1	-0.035049
EIF4A1	-0.035022
BRE	0.034973
PSMG2	0.034962
YWHAG	-0.034764
HSPD1	-0.034750
CD70	0.034691
TUBA1C	-0.034682
AP3S1	-0.034639
NOP58	-0.034582
SLC7A11	-0.034470
ARF4	0.034423
NARS	-0.034382
H3F3B	-0.034296
RPL7L1	-0.034123
MRPL3	-0.033991
AARS	-0.033766
CLIC3	0.033729
ATP5C1	-0.033563
RACGAP1	-0.033561
PSMB4	0.033450
SSB	-0.033440
SLIRP	-0.033396
LAPTM4A	0.033383
NMU	0.033313
MSN	0.033219
AXL	0.033194
FHL2	0.033138
MRPS10	-0.033080
SPP1	-0.033005
TUBB	0.032992
ATP5E	0.032469
RPL23A	-0.032288
CCNG1	0.032231
PDGFC	0.032112
NDUFA11	0.032071
PTRF	0.032042
EIF3G	0.032004
FAU	0.031905
NDUFV2	-0.031842
NUPR1	-0.031810
S100A4	-0.031773
CNN3	0.031770
PFDN5	0.031696
EIF5	-0.031585
CNN2	0.031425
MRPL33	0.031373
SUMO2	0.031275
IGFBP7	0.031239
CSRP1	0.031236
FLRT3	0.031172
RPF2	-0.030982
PSG3	-0.030923
NME1	-0.030875
GPX4	0.030850
TIMP1	0.030843
RABAC1	0.030703
BTF3	0.030677
DCTN3	0.030674
RPL39	0.030549
VAT1	0.030458
SEPHS2	-0.030275
CYR61	0.030208
NQO2	-0.030176
FSTL1	0.030162
FAM96B	0.030085
C19orf70	0.030079
TSPAN1	-0.029875
TMA7	0.029848
CCT3	-0.029727
FLNA	0.029706
TKT	0.029536
TRMT112	-0.029398
TAGLN	0.029390
TAGLN2	0.029156
AHCY	0.029097
ALCAM	0.029047
CD81	0.028986
COL5A1	0.028983
RPS23	0.028955
MYL12A	0.028935
PPA1	-0.028839
SLC3A2	-0.028833
SERBP1	-0.028694
RRM2	-0.028528
GHITM	-0.028396
COX1	-0.028299
CTSA	0.028252
HMGB1	-0.028142
ANP32B	-0.028078
NONO	0.028020
CUTA	0.028014
CAPG	0.027991
RBBP7	-0.027977
RPS16	0.027943
S100A16	0.027839
PSMD14	-0.027798
JTB	-0.027795
HINT1	-0.027662
KARS	0.027629
NFKBIA	0.027520
RAB31	0.027501
PDP1	0.027484
SEC13	0.027393
LAMTOR1	0.027377
POLR2E	0.027273
PEBP1	0.027194
RPS25	0.027034
WDR54	0.027010
ACTN1	0.026940
KPNB1	-0.026917
YWHAB	0.026797
HSPA1A	0.026758
P4HB	0.026439
ANXA5	0.026430
COL5A2	-0.026292
MTHFD2	-0.026226
TXNDC12	-0.026209
F3	0.026163
RPS19	0.026081
PLIN3	0.025974
CDK2AP1	0.025821
CDA	0.025670
RPL3	0.025597
PFDN2	-0.025541
EGR1	0.025306
FABP5	0.025300
DBI	-0.025266
TGFB1I1	0.025227
OAT	-0.025189
SNHG6	0.025180
GAS5	-0.025171
THBS1	0.025047
RPL4	-0.025014
PABPC1	0.024927
NT5C3A	-0.024785
APP	0.024736
SLC25A5	-0.024646
RPS2	-0.024626
CYCS	-0.024526
PSMD8	0.024494
NQO1	-0.024494
SCAND1	0.024444
NDUFAF3	0.024431
C12orf57	0.024379
PSMC1	-0.024379
RPS6	0.024333
HDDC2	-0.024324
PTPLAD1	-0.024299
PSMB8	0.024170
GTSF1	-0.024169
CCT2	-0.024150
ADAMTS1	0.024150
MARCKSL1	0.024095
SNRPG	-0.024076
ITGAE	-0.024039
RPL15	0.023959
AP2S1	0.023942
RNPS1	-0.023855
EIF4H	-0.023846
PPIA	-0.023832
ECI2	-0.023787
GSTP1	0.023661
LASP1	0.023630
COX4I1	0.023602
ATP6V0D1	0.023513
C1QBP	-0.023465
TMEM263	0.023463
HSPA5	-0.023377
LOXL1	0.023200
NAP1L1	0.023171
FRMD6	0.023105
PDIA6	-0.023095
COL1A2	0.022971
UXT	0.022929
SNHG8	-0.022923
MARS	-0.022907
DEK	-0.022867
CD99	0.022798
C1orf43	-0.022772
TMEM123	0.022770
PCNA	0.022769
RPLP0	0.022758
DAW1	-0.022682
TENM2	0.022659
DSTN	0.022645
LAPTM4B	0.022634
CUEDC2	0.022533
PGM1	0.022370
TRIM16	-0.022365
C19orf43	0.022346
ETF1	-0.022209
DHX15	-0.022199
IMPA2	-0.022195
GNG11	0.022192
EIF3E	0.022131
TRNP1	-0.022127
MYH9	0.022120
SRPX	0.022118
TRIM28	0.022102
EIF3A	-0.022030
SHFM1	-0.021930
NCL	-0.021911
SMIM15	-0.021855
CPNE2	0.021845
MRPL51	0.021823
EIF5A	-0.021795
TMEM5	-0.021683
UBL5	0.021644
RNF145	-0.021640
CYSTM1	-0.021633
COL1A1	0.021601
HEG1	0.021525
GLRX	0.021524
LTA4H	0.021512
BUB3	-0.021494
TUBA1B	-0.021472
HSBP1	0.021392
C19orf53	0.021314
COTL1	0.021207
LIMA1	-0.021194
PIR	-0.021182
BRK1	0.021169
PPP1R15B	-0.021156
PRMT1	-0.021132
SPANXB1	0.021094
SNRNP25	-0.021032
GBE1	0.020941
PEG10	-0.020940
ROMO1	0.020938
C4orf48	0.020841
S100A13	0.020759
TXNDC17	-0.020632
NPC2	0.020498
MIF	0.020495
EMP3	0.020468
HMGN2	-0.020464
PHB2	0.020434
USP1	-0.020425
BZW1	-0.020421
MLPH	0.020322
DKC1	-0.020279
XRCC6	-0.020250
GOT2	0.020243
ECHDC1	-0.020221
MIEN1	-0.020208
GLTSCR2	0.020030
CD164	-0.019995
KLHDC8B	0.019949
HMGB2	-0.019920
TXNL4A	-0.019837
SNX3	-0.019828
AATF	-0.019817
GLO1	-0.019816
IGFBP3	-0.019776
NDUFC1	-0.019741
PSME1	0.019705
C14orf2	-0.019687
CDIPT	0.019669
NDUFA3	0.019531
PIGP	-0.019531
BASP1	0.019512
SSR4	0.019447
ENOPH1	-0.019438
HLA-G	0.019435
HEBP1	0.019426
IFNGR2	0.019424
SNHG19	0.019364
COX3	-0.019319
TM2D2	0.019089
KTN1	-0.019088
PLS3	-0.019018
ANXA6	0.018982
SH3BGRL3	0.018968
UQCRH	0.018891
PRDX3	-0.018825
RPS27L	0.018815
FAM129A	-0.018802
LDHB	-0.018749
SMYD3	-0.018685
PSMD4	0.018631
POLR2J	-0.018619
PAICS	-0.018606
MYBL2	0.018596
CDC26	0.018589
PDZK1	-0.018569
KIAA0101	-0.018537
ARF6	-0.018515
PNPT1	-0.018513
ETFA	-0.018450
UGCG	0.018415
BOLA3	-0.018337
ATP5B	-0.018331
TMEM230	0.018315
YME1L1	-0.018264
TMEM203	0.018214
ANP32E	-0.018163
RBX1	0.018126
C6orf62	-0.018074
DDIT3	-0.017983
GABARAP	0.017935
CYB5R3	0.017930
HNRNPA2B1	-0.017929
PITPNB	-0.017916
RRAGA	0.017907
ANO6	-0.017884
CCT6A	-0.017824
PFKM	-0.017818
MT1F	0.017815
UQCRC2	-0.017772
TCF25	0.017730
PARK7	0.017652
CDC25B	0.017638
MRFAP1	0.017612
OST4	0.017607
TFPI2	0.017588
SLC7A5	-0.017541
DAPK1	0.017527
HAX1	-0.017521
PTDSS1	0.017448
EPRS	-0.017366
MTIF2	-0.017353
SUMO3	0.017334
PDCD10	0.017328
TUBB6	0.017321
RPL18	0.017300
UGDH	-0.017289
PRDX4	0.017267
PSG6	-0.017259
RPL10A	-0.017208
MRPS33	-0.017145
CBWD1	-0.017144
HUWE1	0.017104
SLC1A5	-0.017087
COPRS	-0.017083
FAM35A	-0.017028
CBX1	-0.017012
PRPF8	-0.016992
PSMB6	-0.016976
DNAJA3	-0.016937
SMNDC1	-0.016889
HNRNPK	-0.016871
DNAJB11	-0.016862
YWHAE	-0.016861
SURF4	0.016844
PALLD	0.016839
NOSIP	0.016836
NEK7	0.016835
PIN1	0.016833
MTX2	-0.016826
METTL5	-0.016813
BMI1	-0.016801
CAP1	0.016721
PPP4C	-0.016695
STAG2	-0.016685
SRP19	-0.016642