!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!cell_type	MCF7cells
!pert_name	estradiol
!pert_id	CHEBI:23965
!organism	human
!pert_type	chemical
!end_metadata
GREB1	0.058954
PKIB	0.052267
IGSF1	0.051313
CTGF	-0.048879
MGP	0.047826
MGP	0.047205
CTGF	-0.045306
PLA2G10	-0.043865
RAB31	0.043681
UPK1A	-0.043356
SFXN2	0.042812
ANG	-0.041592
DEPTOR	0.041138
CXCL12	0.041132
CDH26	0.039658
RERG	0.038393
PGR	0.038245
PRSS23	0.037746
SGK1	0.037503
SPRY1	-0.037210
CXCL12	0.036971
DEPTOR	0.036630
HEY2	0.035819
SCNN1A	-0.035532
EPAS1	-0.035334
IGSF1	0.033246
ABCA1	-0.033040
CXCL12	0.032281
CA12	0.032167
FGD3	-0.031875
OLFM1	0.031771
IGSF1	0.031659
GDF15	-0.031604
TSC22D3	-0.031051
SALL4	-0.030971
KRT16P2	0.030589
ANKRD33	0.030219
P2RX2	-0.029895
CYP26B1	0.029853
MYB	0.029564
RAPGEFL1	0.029563
VAMP5	-0.029482
SOX9	-0.029423
TMEM164	0.029304
EXO1	0.029288
RAB27B	-0.029279
IGFBP3	-0.029184
HS3ST3A1	0.028814
TNS3	-0.028618
HIST1H3H	-0.028605
YPEL3	-0.028310
TMEM150A	-0.028214
SNAI2	-0.028027
TUBB6	0.027969
CALCR	0.027968
TM4SF1	-0.027947
CAPN13	-0.027895
GRHL3	-0.027829
CDH26	0.027780
ADM	-0.027215
RASD1	-0.027186
FAM43A	-0.027151
TUBA3D	0.027133
RGS22	0.027109
EGR3	0.027100
TFPI	-0.026910
RAB26	-0.026881
P4HA2	0.026778
SGK3	0.026700
ST3GAL1	-0.026638
RGL1	-0.026539
TPD52L1	0.026538
DDIT4	-0.026536
SPIRE2	-0.026530
SYBU	0.026419
SPOCK1	0.026365
ZNF750	-0.026347
SLC29A3	-0.026341
KLHL24	-0.026331
HIST1H2BD	-0.026315
CAB39L	-0.026293
SERPINA3	0.026235
FKBP4	0.026169
LIMA1	-0.026031
PRKCQ	0.026022
FAM174B	-0.026002
ELF3	-0.025872
RPL36A	0.025868
AK4	0.025821
KRT86	-0.025785
LMCD1	-0.025769
SELENBP1	-0.025631
GAL	0.025550
SYTL4	0.025475
CYSRT1	-0.025287
TPD52L1	0.025269
CD68	0.025267
HIST1H2AC	-0.025187
RRM2	0.025077
SMAGP	-0.025060
TUBB6	0.025055
HIST1H2BG	-0.024847
CAPN5	-0.024832
AKR1C3	-0.024691
TGFB3	-0.024618
IGFBP4	0.024605
IL17RB	0.024547
KPNA2	0.024497
PRICKLE1	-0.024396
FOS	0.024391
RND3	-0.024217
DRAM1	-0.024097
RET	0.024050
HIST2H2AA3	-0.023977
HCAR1	-0.023955
MCM10	0.023925
PSCA	-0.023875
TGFA	0.023777
TSC22D3	-0.023701
CYP24A1	0.023642
GRB14	-0.023617
NAV2	0.023601
SLC31A2	-0.023421
AK4	0.023412
CA12	0.023344
HEY1	-0.023314
CYP1A1	-0.023252
BMF	-0.023224
SMAGP	-0.023193
C17orf82	-0.023147
CBX1	0.023120
SPRY1	-0.023120
MOCS1	-0.023098
ISG20	0.023003
FAM110A	-0.022978
RGCC	-0.022974
EFNA1	-0.022898
DSCC1	0.022892
JUNB	-0.022831
HIST2H2AA3	-0.022796
CALCOCO1	-0.022655
CENPH	0.022576
GPR68	0.022538
TFPI	-0.022501
HIST1H2BK	-0.022462
BMF	-0.022433
ANXA9	-0.022361
ID1	-0.022342
LONRF2	0.022263
FRAS1	-0.022240
TYMS	0.022211
TRAK1	-0.022198
RCSD1	0.022182
MXD4	-0.022041
MB	-0.021990
FAM110B	-0.021931
TP53INP1	-0.021878
FOSB	-0.021867
ABCC3	-0.021807
CLDN9	-0.021740
HSD17B11	-0.021737
PNPLA7	-0.021590
P4HA2	0.021547
CHEK2	0.021471
WISP2	0.021448
GRAMD1A	-0.021447
APOD	-0.021404
BAMBI	-0.021381
SOX3	0.021361
RAD54L	0.021302
HIST2H2BE	-0.021295
PLAC1	0.021274
NTN4	-0.021261
PCP4	0.021232
EFNA1	-0.021135
CA5B	-0.021121
TMPRSS2	-0.021069
AGR3	0.020951
MTHFD2	0.020949
TGFA	0.020928
DHFR	0.020917
UPK3B	-0.020916
NME2	0.020905
TMEM194A	0.020891
CDH26	0.020876
DLL1	-0.020839
IGFBP3	-0.020821
DAB2	-0.020795
CELSR2	0.020779
IGDCC3	-0.020738
HIST1H2BD	-0.020731
KRT16	0.020686
GRB7	-0.020603
TFPI2	0.020556
ZNF704	-0.020547
BCAS3	-0.020530
PACS1	-0.020513
RAP1GAP	-0.020497
OCEL1	-0.020483
CDK6	-0.020443
GREB1	0.020442
CYP26A1	-0.020432
BCL2L1	-0.020421
OSBPL7	-0.020410
DIO1	-0.020380
HIST1H2AM	-0.020367
FOXD2	-0.020349
BTG2	-0.020344
ERBB2	-0.020341
PPFIBP2	-0.020310
TUBB2A	0.020304
ZNF467	-0.020301
CDC45	0.020292
MB	-0.020285
DHRS3	-0.020228
C1QTNF6	0.020208
FZD2	-0.020160
GSTM3	-0.020103
DHRS2	0.020092
ARHGAP36	0.020081
CHAF1B	0.020079
CASP6	0.020069
RAD51	0.020062
NBEA	-0.020040
RPRM	-0.020028
SLBP	0.020028
TIPIN	0.020007
CDCA7	0.019998
ABHD11	-0.019996
CRY2	-0.019993
PLEKHF2	-0.019864
MCM10	0.019862
MCM7	0.019860
CTSH	-0.019858
CRISPLD2	-0.019852
ZWINT	0.019789
GMNN	0.019762
DUT	0.019713
SYNDIG1	0.019703
ALDH3B1	-0.019678
FBXO32	-0.019644
ANKRD50	-0.019637
ACAT2	0.019582
RNF144B	-0.019562
LDHA	0.019547
CASP8	0.019543
PDCD5	0.019520
SLC22A4	0.019520
KIAA1683	-0.019491
CDK1	0.019443
EME1	0.019440
MSX2	-0.019401
VPS51	-0.019352
NFE2L3	0.019311
NCOA7	-0.019284
CDC25A	0.019263
LRP8	0.019252
FBXO5	0.019200
ATP6V0A4	-0.019192
EEF1D	-0.019127
HES1	-0.019109
TSC22D3	-0.019073
TICRR	0.019055
RBBP4	0.019035
MZF1	-0.019034
TPM1	0.018986
LRRFIP2	0.018967
SPC25	0.018939
SPC25	0.018899
FAM72D	0.018896
HSPB8	0.018887
SIK1	-0.018882
RPS7	0.018869
S100P	-0.018787
GLA	0.018756
GOLT1A	-0.018747
HSD17B11	-0.018713
ANXA2P1	0.018703
ZDHHC22	0.018681
TGFB2	-0.018671
OLFM1	0.018653
SUOX	-0.018649
TGFBI	-0.018648
FEN1	0.018632
FABP5	0.018594
COL9A2	-0.018587
PIK3IP1	-0.018543
RGS2	-0.018543
UBE2T	0.018541
SLC30A1	-0.018510
PAICS	0.018499
PCNA	0.018496
GABBR2	-0.018494
P2RX4	-0.018479
LTBP3	-0.018472
PCDH7	-0.018441
MCM4	0.018379
CD44	0.018373
ST8SIA4	-0.018359
KLHL35	-0.018260
TMPO	0.018248
FAIM	0.018248
ZNF296	-0.018239
FAM25A	0.018238
HBEGF	-0.018238
SLC22A5	0.018220
HIST3H2A	-0.018196
ABCC5	-0.018196
ZNF581	-0.018175
GNE	-0.018147
MRPL19	0.018146
SAT1	-0.018115
PMAIP1	0.018099
ZFPM1	-0.018090
CAPN9	-0.018083
MAD2L1	0.018072
CCT3	0.018040
MAF	-0.018030
ADPRHL1	-0.018018
ACTL6A	0.018006
NBEA	-0.018004
ALDH4A1	-0.017986
TUBB2A	0.017941
COBLL1	-0.017918
SERPINA5	0.017911
CAPN9	-0.017897
SLC2A6	-0.017887
TP53INP1	-0.017868
FOXN3	-0.017864
SMAGP	-0.017860
CEP85	0.017851
HPRT1	0.017807
LOC284379	-0.017748
TPM3P9	0.017743
MGAT5	0.017735
EXOSC3	0.017732
HLA-DMA	-0.017724
FAM63A	-0.017699
HPRT1	0.017688
TMEM26	0.017676
MELK	0.017654
MAP3K8	-0.017641
MED16	-0.017608
CMSS1	0.017605
HIST1H3D	-0.017603
UNG	0.017580
SLC47A1	0.017545
GPR160	-0.017538
ABTB1	-0.017523
FAM20C	-0.017517
MCM4	0.017506
FHL1	0.017494
FKBP5	0.017481
RET	0.017454
C9orf106	-0.017454
RPS7	0.017454
CA2	0.017450
CAMK2N1	-0.017445
SLC25A15	0.017441
RTN2	-0.017436
RGS16	-0.017420
PTMS	-0.017418
TSKU	-0.017415
BTG3	0.017413
PTGES	0.017391
EPB41L4A-AS2	-0.017384
SLC29A1	0.017382
GART	0.017377
CHEK1	0.017375
MAFB	0.017355
UHRF1	0.017351
CACYBP	0.017304
IFT140	-0.017299
CHD5	0.017295
GALNT4	0.017292
ID3	-0.017286
MID2	-0.017281
SERPINB1	-0.017278
HOXA5	-0.017254
DBP	-0.017240
AGR2	0.017226
CRACR2B	-0.017223
SGK3	0.017221
TOMM5	0.017219
HELZ2	-0.017218
IRF2BPL	-0.017212
NME1	0.017206
MYL5	-0.017197
SEMA3B	0.017196
CREBRF	-0.017193
MREG	0.017184
DUT	0.017169
IRF9	-0.017153
ST8SIA4	-0.017135
HSPA12A	0.017128
SH3RF2	0.017112
NCAPH	0.017100
CORO2A	-0.017077
ECH1	-0.017067
PNPLA2	-0.017048
FANCI	0.017032
RIPK4	-0.017028
EPB41L5	-0.017026
UPK3B	-0.017024
ST3GAL4	-0.016992
LRRFIP2	0.016981
NFKBIZ	-0.016932
ZNF232	0.016925
ANPEP	0.016920
MND1	0.016899
RAMP3	0.016896
PITPNM1	-0.016874
ATAD2	0.016872
HIGD1A	0.016865
DCUN1D3	0.016859
PRKCD	-0.016838
C1orf112	0.016813
SULF2	0.016806
PPP2R2C	0.016798
GINS3	0.016785
PVRL3	-0.016780
GRN	-0.016779
FAM110A	-0.016771
MUCL1	-0.016767
RRNAD1	-0.016747
CYP51A1	0.016745
BRCA1	0.016709
SLC25A19	0.016705
ARHGEF39	0.016697
OTUD3	-0.016686
GRIN3B	-0.016685
ORC6	0.016649
GINS4	0.016605
ACSS1	-0.016589
LOC146880	0.016585
FEN1	0.016583
TBC1D2	-0.016571
SYTL1	-0.016570
UNC93B1	-0.016557
SP2	-0.016553
SEPT5	0.016551
FDPS	0.016550
CDKN2B	-0.016544
G3BP1	0.016538
HIST2H4A	-0.016531
FAM107B	-0.016521
CEP70	-0.016516
FAM83A	-0.016514
YWHAG	0.016513
LRP10	-0.016498
ATP2C2	-0.016497
VAMP1	-0.016484
KIF24	0.016476
SOCS2	-0.016475
ATP2A3	-0.016469
TRAK1	-0.016465
SKP2	0.016457
CARS2	0.016452
RNASE4	-0.016445
OMA1	-0.016443
LRIG1	0.016436
RAP1GAP2	-0.016409
MCM6	0.016396
CYP2J2	-0.016379
HIST1H4H	-0.016366
UPK2	-0.016355
ARSB	0.016349
STARD10	-0.016342
PLLP	-0.016335
GLRX2	0.016320
HOPX	-0.016318
L3HYPDH	0.016315
HIGD1A	0.016305
BCAS1	-0.016279
CLIC3	-0.016258
NAB2	0.016239
CCDC34	0.016238
TOM1	-0.016237
APOBEC3B	-0.016234
PWWP2B	-0.016229
LPCAT1	0.016219
FAM167A	-0.016213
RGS10	0.016203
TUFT1	-0.016201
ZSCAN29	0.016196
LRRC59	0.016180
NT5C2	0.016169
CTPS1	0.016155
SVIL	0.016143
RBP7	0.016133
N4BP2L2	-0.016129
CAV2	0.016118
DPP7	-0.016103
SLC35C1	-0.016075
NOP56	0.016062
CAB39L	-0.016046
NFAM1	-0.016038
RCAN1	-0.016037
SLC7A5	0.016032
EZH2	0.016023