!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Doxorubicin
!smiles	CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
!drugbank_id	DB00997
!pubchem_cid	31703
!cell_type	KJD SV40 virus transformed epidermal keratinocyte
!organism	human
!end_metadata
RNA28S5	0.068142
FOSB	0.063062
RASD1	0.059343
ID2	0.054104
RNVU1-18	0.051409
RNU1-3	0.050831
GSTM3	0.050746
RNVU1-7	0.050705
INSM2	0.050587
ULBP2	0.048772
ZCCHC12	0.048674
GJB2	0.048331
RGCC	0.048076
SNORD3A	0.047984
RN7SK	0.047863
MAGT1	0.047470
RNA18S5	0.046969
SNORD3D	0.046866
NDRG1	0.046865
VASN	0.046480
RGS16	0.046084
SNORD31	0.045227
RNU1-1	0.044902
SAT1	0.044579
CA2	0.044475
SNORD13	0.044130
FAM46A	0.043907
FUCA1	0.043265
GSTT2	0.042670
SOX4	0.041956
HIST1H2AE	0.041950
CRABP2	0.041612
FOXC1	0.041381
SOX9	0.041328
RPS7	-0.041009
HIST2H2BE	0.040376
HIST1H2AM	0.039657
FOXO4	0.039555
HAND1	0.038837
RNU1-28P	0.038823
FOXQ1	0.038351
ATP5O	-0.038020
ALKBH2	0.037927
SLU7	0.037759
DKK1	-0.037642
SIX4	0.037130
HIST1H3H	0.036952
GARS	-0.036891
RASIP1	-0.036727
LSM2	-0.036605
SNORD3C	0.035935
DHDH	0.035805
RNU6-1	0.035615
MSX1	0.035376
HIST1H3F	0.035086
BAMBI	0.034789
ANXA2R	0.034710
H1F0	-0.034658
C14orf93	0.034588
HIST2H2AA3	0.034586
ZIC2	0.034155
HIST2H2AA4	0.034068
MYLIP	0.033922
RSRP1	0.033865
THBS1	-0.033826
RBM14	-0.033771
MAP1LC3B	0.033770
GADD45B	0.033743
ODC1	-0.033693
TMEM158	0.033636
NXF1	0.033540
DKC1	-0.033445
RNU6-15P	0.033307
SSBP1	-0.033279
IRF3	0.033274
C16orf93	0.033140
CD27-AS1	0.033130
PSMG1	-0.033012
SMARCB1	-0.032976
RNA5S9	0.032902
TOMM20	-0.032752
FAM84B	0.032632
CEL	0.032516
MICB	0.032206
C7orf50	-0.032133
NDUFS4	-0.032077
KCTD13	0.031791
HIST2H2AC	0.031772
EPHA4	0.031720
C9orf152	0.031685
PSMD14	-0.031685
CALM1	-0.031562
CDK2AP2	0.031550
LINC00936	0.031548
ABCE1	-0.031403
METTL5	-0.031262
TMEM126A	-0.031234
GINS4	0.031221
KATNB1	0.030944
CCNO	0.030811
HBP1	0.030802
BCL6	0.030700
EPRS	-0.030698
H2AFJ	0.030308
HIST3H2A	0.030159
YPEL1	0.030106
HIST1H4H	0.030009
NDUFV2	-0.029969
LOC644936	-0.029931
NR2F1	0.029870
C17orf96	0.029715
CRISPLD2	0.029645
FOS	0.029631
NOL7	-0.029597
NEU1	0.029517
NMB	0.029496
RPL21	-0.029470
HIST1H2BG	0.029380
FLNB	-0.029361
CTPS1	-0.029260
TMBIM4	-0.029083
SET	-0.028995
CYR61	-0.028934
IFI6	0.028890
EPHX1	0.028839
ENO3	0.028608
SNORD110	0.028605
KPNB1	-0.028605
NEUROG2	0.028602
ACTA2	0.028570
VPS29	-0.028524
SMS	-0.028519
HNRNPA0	-0.028452
DDIT4L	0.028416
LSMEM1	0.028410
RNF122	0.028379
FAM167A	-0.028375
MTHFS	-0.028362
EXOSC3	-0.028247
CCNB2	-0.028241
DEDD2	0.028130
MAFB	0.028120
CYP26B1	0.028105
FLNC	-0.028078
CSE1L	-0.028025
APOE	0.027989
NARF	0.027973
ATIC	-0.027963
C19orf10	0.027940
LOC100128288	0.027907
EGR2	0.027878
PDIA6	0.027847
PWP1	-0.027758
C7orf43	0.027701
DUSP19	0.027613
PIGY	-0.027581
SNORD22	0.027536
GTF2B	0.027481
CHMP1B	0.027460
FAM98A	-0.027448
E2F2	0.027442
KIFC2	0.027403
YPEL5	0.027386
MFGE8	0.027354
PAFAH1B3	-0.027353
RBM25	-0.027336
HIST1H4C	-0.027296
HIST1H3D	0.027268
GGT1	0.027255
TUBB3	0.027230
RAET1G	0.027220
AP3B2	0.027213
GLDC	0.027156
DUSP12	-0.027132
IDH1	0.027125
DLL1	0.027117
CD14	0.027107
EMG1	-0.027090
RAD23B	-0.027084
KRT80	-0.027040
MCOLN1	0.026978
CARM1	-0.026924
TNFRSF10D	0.026917
SYNCRIP	-0.026876
HIRIP3	0.026874
ZNF425	0.026870
TNFRSF1A	-0.026815
JSRP1	0.026809
GNB1	-0.026800
SLC16A10	0.026777
UBE3B	0.026760
ANKRA2	0.026674
GSTT2B	0.026666
BCAR3	-0.026616
DEK	-0.026594
WDR18	-0.026529
NSMCE4A	-0.026518
ANKRD1	-0.026463
CORO1C	-0.026445
BCKDK	-0.026438
MMADHC	-0.026421
MMD	0.026415
SNHG9	0.026391
CXCR4	0.026370
AXIN2	0.026302
CDC42EP4	0.026286
LRRC8A	0.026284
FAM109A	0.026257
CDIPT	0.026243
YTHDF1	-0.026178
HARS2	-0.026135
CTSB	0.026073
PFAS	-0.026021
CDO1	0.026004
RND1	0.025958
MRFAP1	-0.025942
POLA2	-0.025930
ALKBH6	0.025917
LDHA	-0.025910
CLP1	0.025893
MFSD11	0.025890
LMOD3	0.025868
SSR1	-0.025868
C1orf162	0.025739
KLF9	0.025681
GADD45G	0.025653
ADSL	-0.025642
TNFRSF12A	-0.025608
NDUFA12	-0.025562
DLX3	0.025545
IGFLR1	0.025510
FBL	-0.025489
MRPL20	-0.025465
PCMT1	-0.025452
ID3	-0.025446
AARS	-0.025431
RNU4-2	0.025419
HOXA5	0.025365
RNASEK	0.025353
PPP1CC	-0.025329
FKBP14	0.025272
HOXB7	0.025268
DCBLD2	-0.025253
BSDC1	0.025240
TCTEX1D2	-0.025239
JUND	-0.025223
TRIP13	-0.025214
KRT19	-0.025175
IBA57	0.025168
USP49	0.025166
CTSV	0.025159
TRAPPC6A	0.025086
GFI1	0.025082
SLC30A3	0.025055
DDX1	-0.025018
BOLA1	0.024999
FAM90A1	0.024990
COMMD7	-0.024969
GRPEL1	0.024944
SDC4	0.024936
MYB	0.024925
HIATL2	0.024883
EGR1	0.024820
EPB41L4A-AS2	0.024802
CDR2	0.024801
R3HDM4	-0.024652
U2AF1L4	0.024626
HDDC2	-0.024545
CST6	0.024510
HSPB8	0.024482
RPL7A	-0.024480
KDM5B	0.024446
MAP4K2	-0.024441
CKB	0.024438
CCT2	-0.024435
E2F3	0.024422
SIX5	0.024415
FBXO8	0.024390
CANT1	-0.024341
ZMYND15	0.024335
PATL1	-0.024319
KCTD20	-0.024294
HIST1H3B	0.024262
IFI44	-0.024258
C17orf70	-0.024233
HIST1H2AC	0.024216
PAFAH1B1	-0.024215
HLA-E	0.024186
ZFP36	0.024142
YRDC	0.024140
SLC4A11	0.024126
HNRNPD	-0.024115
HSD17B6	0.024115
TGFB3	0.024057
CCNB1	-0.024048
HNRNPR	-0.024042
CREBRF	0.024032
ZW10	-0.023990
SECISBP2	0.023978
PGD	0.023929
OVGP1	0.023920
UAP1	-0.023813
CENPW	-0.023808
RPL39L	-0.023802
ANLN	-0.023794
LEPRE1	0.023783
RPL21P28	-0.023763
NCKAP5L	0.023702
NUP85	-0.023693
TCHH	0.023674
LEF1	0.023662
TMEM14B	-0.023648
CCT3	-0.023587
GTF2E2	-0.023556
FBXL6	0.023515
BCAT1	-0.023493
SYDE1	-0.023488
RPIA	0.023442
KIF11	-0.023439
GTF2F2	-0.023379
BIN3	0.023360
VDAC3	-0.023352
LRRFIP1	0.023331
PUS7	-0.023325
FRAT2	0.023322
TP53I13	0.023307
CITED4	0.023302
MXD4	0.023265
LAMTOR1	-0.023257
UTP11L	-0.023256
GFPT2	0.023239
NDUFAB1	-0.023224
RRNAD1	0.023210
ULBP1	0.023185
RPL23	-0.023184
NDUFA7	0.023165
POLR2A	0.023149
PTBP3	-0.023131
VEZF1	-0.023123
PMPCB	-0.023092
HES6	0.023052
SRSF9	-0.023042
MALSU1	-0.023015
HNRNPA1P10	-0.022998
TOR4A	-0.022983
OR2B6	0.022974
SSTR2	0.022955
HIST1H4E	0.022947
TRIM8	0.022894
PIM2	0.022893
TNS3	-0.022859
RHBDD2	0.022847
FAM64A	0.022838
ZNF786	0.022822
PNP	0.022789
RPS6	-0.022787
RAB3IL1	-0.022777
IFITM1	0.022770
MRPL22	-0.022750
STK35	0.022730
RNU4-1	0.022727
C15orf52	-0.022703
KLHL28	0.022696
IMPDH2	-0.022676
DMWD	0.022669
NAT9	0.022667
CHKB	0.022661
DNMT1	-0.022644
LSM14A	-0.022639
DTD1	-0.022631
SH3BP5L	0.022624
SMIM14	0.022604
LMNB2	-0.022524
FOXL2NB	0.022509
ELL2	-0.022500
CYP1B1	0.022487
GNRH1	0.022437
ADIRF	0.022417
SDF4	0.022353
VCP	-0.022340
FLJ20021	0.022330
SLC41A1	0.022288
RPS14	-0.022267
HSPA8	-0.022265
LRPAP1	0.022254
GRN	0.022252
EXOSC9	-0.022251
BLZF1	0.022240
RPS25	-0.022238
TMEM209	-0.022194
ACTA1	0.022168
SAMM50	-0.022142
EMP1	-0.022139
PCED1A	0.022130
DECR1	0.022126
BNIP3	-0.022104
PTPN11	-0.022077
PHB	-0.022055
EML4	-0.022025
RABGGTB	-0.022022
PSMB1	-0.022004
SPINT2	0.022000
SNRPA1	-0.021997
RAB10	-0.021941
ZNHIT6	-0.021920
RHBDF1	0.021920
SNRPF	-0.021883
DRG1	-0.021878
RPS6KA4	-0.021859
HLA-DMA	0.021856
CARD10	-0.021855
MED19	0.021834
FBXL12	0.021834
RAB11A	-0.021824
HSD17B7	0.021819
RXRB	0.021812
RBMX	-0.021809
SRP19	-0.021773
RRP15	-0.021715
MARS	-0.021690
NPW	0.021660
PDCD4-AS1	0.021620
ITPKA	0.021609
EIF2B2	0.021605
LSM10	-0.021589
HOXC9	0.021578
PDCD2L	-0.021559
DHX16	-0.021540
EZR	-0.021492
COMMD2	-0.021482
SRRD	-0.021455
SNORD35B	0.021441
GPAA1	0.021392
REXO4	-0.021385
RPL22	-0.021374
RPL17	-0.021374
SHISA2	0.021373
NECAP1	-0.021371
PAN2	0.021361
RPS4X	-0.021358
THBS2	-0.021350
MRPL1	-0.021340
BTBD6	-0.021332
MPP5	-0.021317
ZNF486	0.021278
MRPL21	-0.021276
BOD1	-0.021275
SP2	0.021266
SMIM19	0.021262
USP11	0.021255
AMY1C	-0.021243
AKAP8L	0.021237
CHCHD7	0.021234
SERPINE1	-0.021212
PRPF8	-0.021151
SERBP1	-0.021141
ATP5A1	-0.021135
HIST1H2AB	0.021126
IGFBP5	0.021081
KPNA3	-0.021070
DNAJC7	-0.021059
GANAB	0.021035
RSPRY1	0.021030
EIF3E	-0.021005
MRPL16	-0.021000
BTG1	0.020999
MGARP	0.020989
NBN	-0.020968
CREG1	0.020965
DNAJB1	-0.020945
RRAGA	0.020911
USMG5	0.020910
EIF3M	-0.020902
RAET1L	0.020901
NDUFA2	0.020897
HLA-A	0.020892
COPS5	-0.020887
KHDC1	0.020887
CAV1	-0.020880
C8orf59	-0.020879
ICT1	-0.020868
PRRC1	-0.020837
RGS2	0.020835
COX5A	-0.020824
MRPL24	-0.020821
SPIRE1	-0.020814
ARHGEF10	-0.020800
CDK4	-0.020799
HNRNPA1P33	-0.020798
C14orf2	-0.020793
EP400	-0.020757
PRELID1	-0.020738
SPTAN1	-0.020716
ACTR10	-0.020711
PRDM8	0.020691
FBRS	0.020676
GPS2	0.020648
MXD1	0.020631
MEF2D	0.020629
DDIT3	0.020613