!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!gene	SIRT1
!cell	NSCs/neural progenitors (Sirt1lox/lox)
!perturbation	NestinCre;Sirt1lox/lox (lacks active SIRT1)
!end_metadata
GNG3	-0.075698
CALB2	-0.075661
MOXD1	-0.064953
EPHA3	-0.062850
GRIA1	-0.059551
GPR17	0.056184
SPRR1A	-0.055613
ALDH1A1	-0.055113
PDGFRA	0.053053
PEG3	-0.051887
CAPN6	-0.051397
THY1	0.050526
ASB4	-0.050473
SLIT2	-0.050205
MAMDC2	0.049935
CRABP1	-0.049047
CNTN6	-0.046920
TMEM178B	-0.046055
FAM167A	-0.045477
ECM2	-0.044595
GABRB1	-0.044548
ZCCHC12	-0.044412
MMP3	-0.044381
ITGA8	-0.043959
ATP1A2	0.043806
CHRNA5	-0.043709
C11orf87	-0.043580
LIPG	-0.043577
B3GALT5	-0.042894
SIRT1	-0.042618
TTR	0.040637
PCP4	-0.040355
RAB3C	-0.040286
PLEKHF1	-0.039835
C1QL1	0.039746
PALM2	-0.038642
SOSTDC1	-0.038263
RPS13	0.038181
DGKG	-0.037713
OPTC	-0.037526
CDC42EP3	-0.037448
LPCAT2	-0.037222
SIM2	-0.037036
CCBE1	-0.036822
FXYD6	-0.036727
DIO2	0.036600
CAMK2A	-0.036571
SLCO1C1	0.036499
HMP19	-0.036307
SNRPF	0.036235
GJD2	-0.035707
HS3ST2	-0.035644
OR52B6	-0.035345
EBF1	-0.035184
FGF14	-0.035160
KCNJ2	-0.035078
RPS6KA1	0.034932
LUM	-0.034832
NUDT11	-0.034810
GMNC	0.034783
EFNA5	-0.034293
SNAP25	-0.034025
GRB10	-0.033713
IGFBP5	-0.033330
DGKK	-0.033253
TPPP3	-0.032920
LGI1	-0.032897
GABRA4	-0.032631
RGS5	-0.032605
CTNNA2	-0.032518
TGFB1I1	-0.032496
STMN2	-0.032289
GFRA2	-0.031941
ZIC5	0.031677
LYZ	-0.031616
ATL1	-0.031601
GFAP	0.031508
SLC1A5	0.031487
RGS4	-0.031437
WFDC2	0.031044
BRINP2	0.030946
CCDC3	-0.030907
TIMP1	0.030839
HS3ST1	-0.030788
DEPTOR	-0.030774
BTC	-0.030485
SLC38A3	0.030295
HEY2	-0.030187
CAPSL	-0.030137
INSM1	-0.030078
KLHL29	-0.030036
RPS17	0.030034
POP4	0.029974
PROX1	-0.029959
SSTR2	-0.029852
THBS2	-0.029763
PDE9A	-0.029621
REPS2	-0.029343
PDE11A	0.029341
CBLN1	-0.029248
SPG11	-0.029023
CD93	0.028965
CACNB4	-0.028901
GCNT4	0.028821
FOXC1	0.028697
IFI16	0.028633
OLFML3	-0.028575
CXCL6	-0.028422
RGS2	-0.028334
NRK	-0.028290
CCDC85A	-0.028148
DEPDC1	0.028143
FAM78B	-0.028040
GRIN2A	-0.028030
TMEM145	-0.027946
RASGEF1B	-0.027903
GPR50	-0.027789
RIMBP2	-0.027679
GABRG3	-0.027674
GABRA2	-0.027637
SORBS2	-0.027506
PYGM	0.027497
CLSTN2	-0.027479
FAM26E	-0.027474
LPO	0.027463
CNPY1	-0.027444
IL33	-0.027331
PNMAL2	-0.027294
ENPP3	-0.027267
NNAT	-0.027256
TLR4	0.027190
DDX26B	-0.027170
BRINP3	0.027164
FIBIN	-0.027067
EYA2	-0.027005
MICAL2	-0.026931
RPL10L	0.026910
ZG16	-0.026818
GNG2	-0.026814
CNKSR2	-0.026778
SCG2	-0.026742
OPCML	-0.026717
KCNJ14	-0.026658
SFRP4	-0.026652
ZIC2	0.026636
ARMCX1	-0.026614
LCAT	0.026560
PDPN	0.026402
CACNA2D3	-0.026325
SMARCA1	-0.026282
WBSCR17	0.026269
CD200	-0.026220
GRID2	-0.026213
NDRG2	0.026151
LPPR5	-0.026111
INA	-0.026080
MAPT	-0.026073
SCML4	-0.026034
KCNV1	-0.025999
RSPH4A	-0.025952
PLSCR4	-0.025813
PDHB	0.025715
CXCL10	0.025707
TAGLN3	-0.025674
CHRNB2	-0.025660
CSRNP3	-0.025657
VASH2	-0.025606
GNG11	-0.025470
PGAP1	-0.025408
PDE5A	-0.025351
LRRN3	-0.025318
LYPD4	-0.025292
FOXR2	-0.025266
RND3	-0.025265
VCAN	-0.025261
CACNG5	0.025233
PCYT1B	-0.025230
ADD2	-0.025080
PAK1	-0.024998
APOC4	-0.024989
PKIB	-0.024967
ITGA6	-0.024963
HTR3A	-0.024945
PCOLCE2	0.024913
FMO1	-0.024883
NKAIN2	-0.024880
TNFAIP8	0.024844
QPCT	-0.024809
MRPL42	0.024776
PTPRR	-0.024716
C14orf37	-0.024714
MMP19	0.024686
MYT1	-0.024651
GJC1	0.024616
LAMA4	-0.024581
GLTPD2	-0.024492
LAMA2	-0.024491
DCAF4	-0.024413
PRELP	-0.024364
CYP7B1	-0.024261
RENBP	-0.024151
SLC2A3	-0.024129
FAM81A	-0.024081
TEKT4	-0.024075
WARS2	0.024042
PCDHB15	-0.023992
GJC3	0.023991
SLITRK1	-0.023960
COX7A1	0.023916
PKIG	-0.023889
RAB3B	0.023865
MST4	0.023860
TIMP4	0.023848
GNAO1	-0.023835
RARRES1	-0.023811
CACNA1C	-0.023786
PLXNA4	-0.023748
LRP2	-0.023697
SUCNR1	-0.023683
FAXC	-0.023664
STARD6	0.023657
PARP8	-0.023637
ERBB4	-0.023591
SPP1	0.023533
FAT4	-0.023486
VAT1L	0.023439
ELOVL2	-0.023294
C1orf110	-0.023252
C1orf228	-0.023248
DRP2	-0.023244
DISP2	0.023222
ZNF711	-0.023215
GPR85	-0.023180
LYNX1	0.023178
MAL	-0.023157
CDKL4	-0.023155
PLEKHA2	-0.023138
KCNT1	-0.023127
CASP8	0.023107
PLXDC2	-0.023094
LGR5	-0.023081
FGL2	-0.023052
RTN4RL1	0.023029
HIST1H2BJ	-0.023000
SLC22A15	-0.022990
P4HA3	-0.022979
ODF3L2	-0.022956
FAM195A	0.022951
PDXK	0.022897
BTBD11	0.022896
NPTX1	0.022868
CTLA4	-0.022827
GAP43	-0.022807
PXDC1	0.022749
KRT8	0.022706
ACP6	0.022684
TRPA1	-0.022659
ANKS1B	-0.022628
FAM19A1	-0.022613
KCNH8	-0.022607
SLC9C1	-0.022591
KCNA3	-0.022584
COMMD7	-0.022571
PTK2B	-0.022566
DAPK1	-0.022566
HNMT	0.022558
TRAF5	0.022550
C9orf41	0.022493
PTPRT	-0.022491
SRL	-0.022475
CD36	-0.022460
ARHGDIB	-0.022457
ANKRD35	-0.022436
DEPDC7	0.022434
C2orf88	-0.022414
EPHA7	-0.022389
MAGOHB	0.022375
GRIK2	-0.022340
F2RL2	-0.022339
C1QTNF6	0.022335
ZNF559-ZNF177	0.022326
C3AR1	-0.022298
MFSD6	-0.022245
C17orf58	-0.022242
NCR1	-0.022220
EMILIN2	-0.022211
ASB5	0.022201
EBF3	-0.022143
RAPGEF4	0.022136
NETO1	-0.022134
IQUB	-0.022126
ADRA2B	-0.022124
GYPC	-0.022055
NR5A2	-0.022027
VSTM2A	-0.022007
TSPAN13	-0.021919
DNALI1	-0.021851
ASAH1	0.021829
ZBTB16	-0.021783
LEFTY2	-0.021752
NRP2	-0.021650
CSGALNACT1	-0.021612
GFPT2	0.021583
C2orf81	-0.021570
VGLL3	-0.021554
LPAR1	-0.021534
THBS1	0.021531
TENM3	-0.021529
C8B	-0.021527
MYH4	0.021493
TLR8	-0.021446
SLC8A3	-0.021434
APLP1	-0.021432
CAMK4	-0.021417
KIF11	0.021413
SEC11C	-0.021394
S100A10	-0.021393
CXADR	-0.021390
TSHR	-0.021386
APOD	-0.021375
GPRC5A	-0.021351
TUBA4A	0.021330
CYP4F12	0.021327
SV2C	-0.021306
TAGLN	0.021278
CELSR3	-0.021273
CRYM	-0.021236
USP31	-0.021228
PDE3B	-0.021137
SCNM1	-0.021129
ANK3	0.021121
ERMARD	0.021101
EMR1	-0.021085
BBS1	-0.021070
CLYBL	0.021066
SLC35G2	-0.021018
CACNG3	-0.021015
BASP1	-0.020999
EN2	-0.020989
BDH2	-0.020957
TRIM13	-0.020956
AGTR2	-0.020944
ARHGAP20	-0.020854
CHST1	-0.020854
ZNF608	-0.020805
IL10RB	-0.020763
MTMR11	0.020759
AGO4	-0.020744
PLCE1	-0.020730
ELTD1	-0.020642
SLC2A13	-0.020637
HDAC9	-0.020598
TOX3	-0.020537
CCDC63	-0.020516
SNAP91	-0.020514
RBM24	-0.020457
MOG	-0.020409
CHORDC1	0.020402
PF4	-0.020395
LMO1	0.020380
MSR1	-0.020363
EPHB6	-0.020355
UCP2	-0.020342
CTSH	0.020316
FAM196B	-0.020301
PPP2R2C	-0.020294
ANXA1	-0.020289
BRSK2	-0.020274
SEMA3A	-0.020272
SOX10	0.020243
SYNPO2	-0.020214
CYP1B1	-0.020159
BDKRB2	-0.020129
GJB3	-0.020125
SLC25A24	-0.020121
ALDH1A2	0.020118
TRIM2	-0.020115
CA3	-0.020068
NFU1	0.020042
ITIH5	-0.020014
LGALS3	-0.020010
DPEP2	-0.019993
DQX1	-0.019990
TSHZ2	-0.019955
MSX1	-0.019939
SPEM1	-0.019938
C12orf68	-0.019933
C10orf82	-0.019932
ZIC1	0.019924
SYNPO	-0.019907
POU4F1	-0.019900
LGALS3BP	-0.019895
NDRG1	-0.019892
COL12A1	-0.019878
NPAS2	-0.019866
SKAP2	0.019864
PDZK1	-0.019827
RPL15	0.019827
CA2	0.019824
HTR1B	0.019787
PRRX1	0.019786
CDO1	0.019763
F12	-0.019757
GDAP1	-0.019720
PCDHB3	-0.019715
CD38	-0.019711
HMOX1	0.019652
USP53	-0.019647
GDAP1L1	-0.019644
RPS23	0.019644
KRTAP26-1	0.019633
FOXB1	-0.019626
NID1	-0.019602
CYBB	-0.019581
FLJ22184	-0.019577
RPL7A	0.019566
SCN3B	-0.019564
C4orf33	0.019555
C1orf95	-0.019554
CLDN1	0.019532
IFIT2	-0.019518
RFX3	-0.019502
LRRTM2	-0.019477
SYT1	-0.019477
IL20RA	-0.019461
TMEM37	0.019455
DNER	-0.019411
CXCL14	-0.019380
SLC25A53	-0.019323
RNF182	-0.019320
LOX	0.019315
FEZF2	-0.019300
DUSP4	0.019293
ZFP57	-0.019291
MRPL22	0.019275
IGDCC4	0.019260
HPDL	0.019243
CLDND2	-0.019224
CALML4	-0.019224
RERGL	-0.019212
TMEM258	-0.019165
SLC9A9	-0.019164
ERC2	-0.019161
CEND1	0.019158
FOXD2	-0.019157
DCX	-0.019156
BEX1	-0.019106
SLC44A5	-0.019050
TST	0.019046
KIAA0408	-0.019044
ADRA2A	-0.019032
PTRHD1	0.019020
STOX1	-0.018992
MAFB	-0.018970
TNFSF10	0.018953
KIF5C	-0.018945
STXBP5L	-0.018934
AASS	0.018906
RGS7BP	-0.018901
CST6	0.018900
ZNF329	-0.018874
KIAA1644	-0.018870
C1QTNF3	-0.018837
TNMD	-0.018822
PDE3A	0.018812
P2RY6	-0.018780
DPCR1	-0.018771
LUZP2	-0.018770
KCNK1	0.018704
RSAD2	-0.018700
COG6	-0.018677
IGSF10	-0.018671
ZDBF2	-0.018660
GLIPR1L2	-0.018652
CLCA2	-0.018652
SERPINE1	0.018620
NUDT14	0.018608
DACH2	-0.018600
OR51B4	-0.018592
SLC6A6	-0.018591
TNR	0.018551
ENTPD8	0.018546
PARS2	0.018522
C17orf97	-0.018515
AKAP6	-0.018509
CACNG4	-0.018500
TUBB4A	-0.018499
IQCG	-0.018499
ENPP1	-0.018489
C1orf54	-0.018487
KCNS1	-0.018461
GRIK1	-0.018440
GBP5	-0.018414
WNT5A	-0.018406
TLR3	0.018406
RBPMS	-0.018399
ST8SIA4	-0.018379
MMP2	-0.018376
NGDN	0.018362
SERPINF1	0.018351