!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!cell	A375
!perturbation	MLN4924 
!disease	650nM - 4hr
!end_metadata
HMOX1	0.327119
HSPA1A	0.241500
TXNRD1	0.206227
FTL	0.189874
SRXN1	0.153178
NQO1	0.145908
UBB	-0.131680
GCLM	0.129331
SPRY2	-0.127092
SLC7A11	0.121836
DDIT4	0.117011
HSPA8	0.115353
COX1	-0.114590
UBC	-0.102504
ID1	-0.097113
SLC26A2	-0.095519
CTGF	0.091604
HOXB2	0.091271
FTH1	0.091156
NACAP1	0.085416
DKK1	-0.083602
ERRFI1	-0.082944
TRIM16	0.082839
PSAT1	0.080646
MIR21	0.077275
WNT5A	0.075968
ID3	-0.075878
FTH1P5	0.075612
H1F0	-0.070771
DNAJB1	0.069786
DUSP6	0.068715
NNMT	0.066281
PRDX1	0.065444
MAT2A	0.064974
CTSL	0.063392
PPIF	0.063018
LINC01419	-0.060809
LBR	0.060072
TSPAN13	-0.058687
SGK1	0.058011
CCND1	0.057545
IER3	-0.056710
STK17A	0.056584
SRP14	0.054767
MTHFD2	0.054369
HNRNPA1	-0.053346
YWHAG	0.051594
MANSC1	-0.051518
PTTG1IP	0.050899
HSP90AB1	0.050416
PMAIP1	0.050239
SMURF2	0.050022
HLA-DRA	0.049482
IGF2BP3	0.048812
UAP1	0.048728
OVOS2	0.048140
COX2	-0.047414
SLC20A1	-0.047237
DDX21	0.046900
BNIP3	0.046146
DUSP4	0.045988
FST	-0.045821
UBE2C	0.044854
FBXO30	0.044825
DPM1	0.043664
IRS2	-0.043371
HIST1H4C	-0.043341
EEF2	-0.042717
SMNDC1	0.041989
NARS	0.041864
TM4SF1	0.041654
MAD2L1	0.041395
TGFA	-0.041068
ADM	0.040775
BTG1	-0.040623
TXN	0.040538
WDR82	0.040469
RPS13	0.040354
GARS	0.040343
ZCCHC8	0.040211
ZNF217	0.039738
RPS25	0.038754
INHBA	-0.038741
KPNA2	0.038533
AKR1B1	0.038005
DNTTIP2	0.037985
TMA7	0.037822
ZWINT	0.037598
DKC1	0.037390
RSL24D1	0.037378
CAV1	0.037163
DNAJB4	0.037074
SNRPB2	0.037062
LDHA	0.036808
LINC00657	-0.036730
PLK2	0.036369
TOMM20	0.036337
MT1H	0.036244
S100A2	-0.036076
C20orf24	0.035967
RARS	0.035653
HOXC6	-0.035039
TRIB3	0.034890
SNHG1	-0.034876
PKD1P1	0.034586
APEX1	0.034566
PRNP	0.034556
SLC25A5	0.033992
PTPLAD1	0.033915
MLLT11	0.033805
SLC3A2	0.033622
SLBP	0.033559
EIF4A3	0.033533
KIF11	0.033262
GLA	0.033092
XPOT	0.033011
COX3	-0.032934
HHEX	0.032868
DEPDC7	-0.032610
CCT2	0.032490
RPL34	0.032420
LINC00622	0.032324
NEIL3	0.032269
BTBD3	-0.031900
DNAJA1	0.031756
TUBA1A	-0.031744
SRSF6	-0.031713
SRSF2	0.031640
EEF1B2	-0.031414
PRDX6	0.031318
HSPA5	0.031283
SLITRK6	-0.031113
IRF2BPL	-0.031000
NDUFAB1	0.030746
AGPAT9	-0.030623
ENO1	0.030094
CFL1	-0.030016
GTF2H2	0.030002
POLE3	0.029788
SMAGP	0.029701
POPDC3	0.029273
ARL6IP1	0.029129
GSTP1	0.029008
YWHAZ	-0.028930
HINT1	0.028848
PGAM1	0.028719
RRS1	0.028388
CDK2AP1	-0.028323
TNPO1	0.028210
NAE1	0.027992
ARPC5	0.027962
ERH	0.027932
CDK1	0.027916
SOD1	0.027884
CDC25B	-0.027850
IL17RD	0.027824
RPL36A	-0.027738
UQCRFS1	0.027472
NONO	0.027344
RPL36	0.027214
BAG3	0.027144
ASF1A	0.027060
RPS8	0.027057
TKT	0.027009
OAT	0.027002
TNFRSF1A	0.026992
GRPEL1	0.026934
ARHGAP12	0.026544
USMG5	-0.026507
RPS15	0.026409
USP53	0.026373
HMGN3	-0.026303
RRM2	0.026276
RPL27	0.026179
SNHG5	0.026145
UFC1	-0.026100
EIF3E	0.025964
FAM84B	-0.025856
RPL19	0.025851
SNAPC1	0.025843
ASNS	0.025780
KIAA0907	0.025759
SLC7A5	0.025754
CEBPB	0.025715
TFRC	0.025552
MAGEA3	0.025503
CRY1	0.025259
SNHG6	0.025189
FAM83D	0.025063
TMSB10	-0.024716
NRIP1	-0.024636
HNRNPC	0.024626
GAPDH	0.024623
PUS7	0.024586
PSMA4	0.024561
RPL26	0.024511
TCF7L2	-0.024491
CFAP20	0.024451
PGK1	0.024429
RPL9	0.024420
TIPARP	-0.024346
GAS5	-0.024142
NPTN	0.024066
MARCKSL1	-0.024057
S100A4	-0.024055
RPL39	0.023981
ABHD17C	-0.023963
ATP6	-0.023931
STIP1	0.023659
MRPL27	0.023644
FLRT3	-0.023551
CPOX	0.023505
AMOTL2	0.023383
SNRPE	-0.023340
LINC00326	0.023207
UBL5	0.023180
EIF3I	0.023135
TALDO1	0.023045
SH3BGRL3	-0.022942
ATP6V0B	-0.022933
IER5	0.022882
GLO1	0.022844
CD3EAP	0.022814
ITGAE	0.022806
CDC123	0.022772
TUBB	0.022680
MRFAP1	0.022637
PPARG	-0.022631
PLP2	-0.022592
GHITM	0.022538
ATP5E	-0.022512
LRP8	0.022503
SOX10	-0.022413
DYNLT3	-0.022396
SMIM15	0.022387
STUB1	-0.022350
SNRPG	0.022315
ANKRD50	-0.022256
SPRY4	0.022137
HMGB2	0.022096
ATP5B	0.022020
RAB1B	-0.021988
SRP19	0.021932
EIF2S2	0.021900
PAICS	0.021823
SNRPF	-0.021816
MALT1	0.021804
RPL4	0.021694
IARS	0.021686
MANF	-0.021559
TFPI2	0.021468
NFKBIZ	-0.021254
CD63	-0.021139
NPIPA1	0.021130
BCCIP	0.021041
PHB	0.021030
TMEM2	-0.021029
RCAN1	-0.021020
CCDC59	0.020987
IL13RA2	0.020888
HIF1A	0.020834
PXYLP1	-0.020799
DLEU1	0.020751
NDUFA13	0.020739
ODC1	-0.020729
PSME2	0.020714
HNRNPA2B1	-0.020685
SH2B3	-0.020628
NOP56	0.020580
EXO1	0.020573
SRPX	-0.020505
EIF4H	0.020411
OAZ1	0.020391
S100A10	-0.020379
TRMT10C	0.020371
WWTR1	-0.020345
TPX2	0.020336
GSR	0.020299
ZBTB38	-0.020227
TAF7	-0.020125
RASSF8	-0.020093
PPIA	0.020068
EIF1	0.020016
MRPL33	-0.019956
DEGS1	0.019927
KLF10	-0.019869
SLC25A46	-0.019845
LINC01029	-0.019827
RPL38	-0.019812
SLC25A32	0.019808
HLA-A	0.019802
RPL13A	0.019777
RPL3	0.019769
TM9SF2	0.019650
NAF1	0.019612
RABGGTB	-0.019530
SSR4	0.019493
SHISA2	0.019492
GGCT	0.019388
E2F6	0.019318
MAPK6	0.019315
AKR1C1	0.019311
NUSAP1	0.019296
AHR	-0.019272
RPS14P3	0.019256
GNL3	0.019204
SRSF9	-0.019174
CCNB1	0.019124
TMEM258	0.019084
PPIB	-0.019058
ERP29	0.019014
FOS	-0.019012
FAM96B	-0.019005
SEC61B	0.018986
GBE1	0.018944
RSRP1	0.018869
HK2	0.018868
UHRF1	-0.018853
ERBB3	-0.018747
AXL	-0.018725
RPL29	0.018708
TM2D3	0.018673
PSMD14	0.018673
NEDD8	0.018596
B4GALT5	0.018578
SNORD104	-0.018570
YWHAQ	-0.018545
GPRC5A	-0.018502
RPL6	-0.018473
KRTAP2-3	0.018473
SYTL5	-0.018383
NET1	0.018359
PSMD11	0.018332
ANKRD1	0.018257
MAGEA12	0.018246
MIF	0.018222
RPL35A	0.018147
PLIN2	-0.018141
GRPEL2	0.018134
MRPS24	0.018119
FBL	0.018114
BUB3	0.018085
ALDOA	0.018061
TOMM5	0.018054
PWP1	0.018031
METTL23	-0.018020
FAM60A	0.017921
RPL35	0.017813
MT1X	-0.017808
PITPNB	0.017769
POTEM	-0.017760
CRLF3	0.017750
CTSB	0.017730
GLRX	0.017713
ITGB8	-0.017674
PPA1	0.017672
MSH2	0.017633
PAPD7	0.017623
OPHN1	-0.017605
PRPF19	0.017595
SLC38A1	0.017505
CDC42EP3	-0.017477
DEK	0.017434
TFAP2C	-0.017433
UBE2T	0.017376
RPS4X	0.017343
CHAMP1	-0.017235
ATP1B1	-0.017228
MBD4	0.017221
AMD1	0.017152
ENC1	-0.017147
PDP1	-0.017069
KLF4	-0.017064
EPHA2	0.017063
SRSF5	-0.017058
ATOX1	0.017040
PSMC3	0.017031
RAP2B	0.017030
RRP1B	0.016990
PGM1	0.016913
EIF5A	0.016823
DAP3	0.016795
CNEP1R1	0.016782
RPL32	-0.016763
TPI1	0.016762
DANCR	-0.016743
HMGN4	-0.016726
MAP3K1	0.016675
S100A16	-0.016626
SLMO2	-0.016584
RB1	-0.016575
POP7	0.016508
RTN4	-0.016503
IRS1	0.016460
MALAT1	-0.016449
NOB1	0.016444
TMEM165	0.016429
RAC1	-0.016410
F2RL1	0.016395
ENOPH1	0.016362
LASP1	-0.016345
ALDH1A3	0.016279
CWC15	0.016277
AKR1C3	0.016246
FANCL	-0.016218
DUSP10	-0.016204
MYC	0.016169
NDUFA1	0.016158
NPC2	0.016151
HLA-DPA1	0.016150
RPLP0	0.016150
C11orf48	-0.016127
PRDX3	0.016119
PSMC5	0.016102
RPL36AL	0.016101
COA6	0.016057
MEIS2	-0.016043
MRPS6	-0.016031
MRPL15	0.016022
HARS	0.015983
ANXA5	-0.015959
LRRC8D	0.015928
PRC1	0.015893
TMEM243	0.015880
CD55	-0.015844
RAB10	0.015783
EIF4EBP1	0.015782
SUMO2	0.015778
TIMP1	-0.015710
EXOSC8	0.015661
PHF23	0.015639
CTNNAL1	0.015595
TAGLN2	0.015496
SNHG16	0.015480
TBC1D4	0.015450
TERF2IP	-0.015424
HERPUD1	0.015379
RPL24	-0.015334
ZCRB1	-0.015333
UBE2G1	0.015330
SNX5	-0.015328
BLMH	0.015323
CDK7	0.015290
SOX11	0.015233
MTERF3	0.015201
GCLC	0.015196
TSPO	0.015191
LOC344887	0.015177
COX7C	0.015174
ARL6IP5	-0.015171
TRAM1	0.015137
TES	0.015119
ABCC2	0.015090
RBM7	0.015079
RPL30	0.015074
RPS29	0.015057
TGFBI	0.015037
MARS	0.015030
NGFRAP1	0.015014
PCNA	0.015004
ME1	0.014983
ATP5I	-0.014963
TIMM17A	0.014960
RPL7L1	0.014937
KYNU	0.014922
DHX33	0.014909
YWHAE	-0.014905
PARK7	-0.014858
TOPORS	-0.014845
C2orf69	0.014793
CALM2	0.014789
TVP23B	0.014772
NSA2	0.014762
TNC	-0.014733
RACGAP1	0.014711
CXCL1	0.014697
GMNN	0.014692
FOPNL	0.014680
EIF2A	-0.014673
SRSF1	0.014642
MGST1	0.014623
LRIG3	-0.014616
NDUFB5	-0.014598
CXCL8	0.014549
PDLIM1	0.014533
ZFAND2A	0.014511
AMIGO2	-0.014507
EI24	0.014442
PEA15	0.014415
MINOS1	0.014411
PSMA6	0.014374
RNF111	0.014266
CCDC86	0.014250
RPS17	0.014243
HEY1	0.014232
MRPS21	0.014207
FERMT1	0.014199
TRAPPC4	-0.014196
LDLR	0.014187
COL9A3	-0.014181