!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	2,3,7,8-tetrachlorodibenzo-p-dioxin
!smiles	CC(C)C=CC(=O)ONC(=O)COC1=CC=C(C=C1)[N+](=O)[O-]
!pubchem_cid	10852289
!cell_type	Pituitary gland (postnatal day70 male rats exposed in utero to dioxin at gestational day15)
!organism	rat
!end_metadata
PTGDS	-0.330972
RPL6	-0.219282
TSHB	-0.201668
DLK1	0.186147
TPT1	-0.170723
PRL	-0.144444
DUSP1	-0.140700
RPS26	-0.140103
PCSK1N	0.138068
RESP18	0.137912
RPS6	-0.125112
CTBP1	0.118753
CHGB	-0.118429
ARF5	0.099708
PRDX1	0.097651
LMO4	-0.088707
RPS4Y1	-0.087702
RPL3	-0.087568
RPL8	-0.086255
RPS25	-0.084427
CARTPT	0.084239
CCDC53	0.084218
RPSA	0.083585
TMEM55B	0.082782
UCP2	0.080444
TAC1	-0.077652
RPL35	-0.077428
TRAM1	0.076883
SCG3	-0.075590
TMEM50A	0.074948
DTX2	0.074902
NEFL	0.074572
UBA5	0.074188
ATP5O	0.073575
TXNDC15	0.073377
SV2B	-0.073285
JUNB	-0.073186
RPS14	0.071860
ATP5B	-0.071194
HMGN1	0.070659
PSMB1	0.070282
SLC25A4	-0.070197
CNBP	-0.068018
RPS10	0.067705
EGR1	-0.066447
RPS21	0.064490
RPS8	0.062208
PDIA6	0.061307
OSTC	0.061201
RCN3	0.061005
NDUFB2	0.059772
MAGED1	0.059201
NMB	-0.058153
SIX6	-0.057778
RABAC1	0.057602
PDCD5	0.055278
FTL	0.055093
MAP2K2	0.054403
P4HB	-0.054171
RPL14	-0.053366
THOC7	0.053301
CSTB	0.053170
MRPL18	0.053036
ATP6V1F	0.052845
RPL10	-0.052295
RPS18	-0.051314
PSMC1	0.050682
CCDC104	0.049952
RAB24	0.049917
FOS	-0.049766
RPL19	0.049470
MGP	-0.048629
NDUFA1	0.048450
CD164	-0.048362
RRAGA	-0.048213
H2AFX	-0.048206
RPL26	-0.048064
ALDH1A1	0.047383
EEF1A1	0.047089
MMADHC	0.047073
TIMP1	0.046927
SERBP1	0.045699
VPS11	0.045384
PDE10A	0.045051
SLC1A3	0.044981
VCP	0.044956
BNIP3	-0.044811
RPL18	0.044657
NMU	0.044453
RPS3	-0.044215
HMGCR	-0.043320
TPI1	0.043083
WDR83OS	0.042437
BEX1	-0.042397
RPS17	-0.042168
BTG2	-0.041793
RPL30	-0.041696
IFT20	-0.041570
PNP	-0.041569
MAP1LC3B	0.041564
RPL17	-0.041450
SUMO2	0.040270
NFKBIA	0.040016
ATP6V1B2	0.039773
UQCRHL	-0.039657
TUBA4A	-0.039647
DDX5	-0.039514
GDI2	-0.039359
PSME1	0.039252
EEF2	-0.038233
PSMB4	0.037797
PRDX2	0.037296
NDN	0.036938
ATP5G1	-0.036921
SRP19	0.036493
RPL21	0.036478
RPL7A	0.036350
PSMA6	-0.036299
COX6A1	-0.036014
PTTG1IP	-0.035361
GPX4	-0.034725
DYNLL1	-0.034710
TMEM140	0.034479
RPS7	-0.034382
NAP1L4	0.034131
WFDC1	-0.033965
HDLBP	-0.033726
YWHAE	0.033562
SCG5	-0.033488
TUBA1A	-0.033244
SESN1	0.033194
LAMP1	0.033039
CD63	0.032981
TUBB2A	-0.032954
CST3	0.032829
PCNP	0.032665
CFL1	0.032328
IGF2	-0.032318
HMGCS1	-0.032224
CALR	0.032089
SEC11C	-0.031350
HCFC1R1	0.031308
AP2S1	0.031071
RPL7	-0.031017
TUBA1B	-0.031003
PNRC1	0.030844
PCP4	0.030840
EFNB3	-0.030614
TMEM256	0.030580
CAMK2N1	0.030566
FTH1	-0.030447
GAPDH	-0.030304
SDHC	0.030295
SEC62	-0.030204
TESK1	-0.030124
GNAI2	0.030053
ABHD4	0.029994
ATP6V0C	-0.029993
POLR2I	-0.029839
SRP14	-0.029826
RPS29	0.029597
EIF1B	-0.029528
DNAJA1	-0.029342
REPS1	-0.029223
STMN3	0.028968
HIST1H2BG	0.028967
GPX3	0.028545
ATP6V1G1	-0.028404
MDH1	-0.028267
RPN1	-0.028261
RXRG	0.028249
PSMA7	-0.028164
AP1M1	0.028096
SEPW1	-0.027914
ARPC2	-0.027878
RPL10A	-0.027817
MAP2K3	-0.027751
DAPL1	-0.027708
NDFIP1	-0.027572
RAB3D	-0.027482
PARK7	-0.027241
SNRPN	0.027211
DCTN2	0.027038
SMAD4	0.026651
EEF1A2	0.026565
RPL24	-0.026298
GPC4	-0.026172
PPP2CA	-0.025941
EIF4A2	-0.025801
ACTR10	0.025551
FKBP1A	0.025325
CTNNA1	-0.025259
RPS20	-0.025240
STUB1	0.024980
TMEM208	0.024939
UQCRB	0.024874
COQ10B	-0.024867
HSPD1	-0.024852
ARPC5	-0.024771
TESC	0.024748
RPL13A	-0.024717
TMED4	0.024663
YEATS4	0.024400
FAM98A	-0.024391
SUMO1	0.024382
HBP1	0.024356
APP	-0.024284
ATOX1	0.024263
RPL39	0.024197
FBL	0.024188
PDHB	-0.024137
EIF5A	0.024035
ANXA11	-0.023900
ZER1	0.023472
SCAND1	0.023391
FLCN	0.023372
ATP5G2	0.023314
RTN4	-0.023288
HSP90B1	-0.023269
SNX25	0.023229
GSTP1	-0.023214
ECH1	-0.023161
GABARAP	-0.023068
FAHD1	-0.023063
IRF1	0.023051
PSMB2	-0.022993
PRNP	-0.022976
RPS9	-0.022968
MPV17L2	0.022897
EMP3	0.022847
RPL35A	0.022840
PRKAR1A	0.022717
EMC3	-0.022701
CCT6A	0.022695
MRPS7	0.022570
CCT7	0.022473
ZNF598	-0.022443
ABHD8	0.022439
SERPINB9	-0.022429
MTCH1	0.022427
RPS23	-0.022386
EMC2	0.022349
VTA1	-0.022316
HNRNPL	0.022301
RPS27A	-0.022288
GNB1	0.022240
EXOSC7	0.022217
VKORC1	-0.022103
RPL13	0.022097
TTC13	0.022096
SHARPIN	0.022018
NME2	-0.022009
TMEM134	0.021951
PPIB	-0.021826
RGS7	0.021737
EMC6	0.021704
CHN1	0.021673
NDUFA11	-0.021490
FUCA1	0.021363
CAMTA2	0.021347
SLC25A3	-0.021150
VDAC3	-0.021146
RGS2	-0.021106
GLO1	-0.021056
TUBB4B	-0.020945
ALDOC	0.020917
PSMB10	0.020901
CDC37	0.020797
FAM3C	-0.020745
SCFD1	-0.020742
SEP15	-0.020713
ARHGAP36	0.020711
APLP1	0.020686
PRDX6	-0.020667
RNASEK	0.020480
APRT	0.020447
PFKP	0.020411
ACAT2	-0.020343
PLAT	-0.020197
KDELR1	-0.020130
HSPA5	-0.020125
GSTO1	0.020120
PTPRN	0.020004
REXO2	-0.019978
PTP4A1	-0.019857
LY6E	-0.019832
FTO	0.019832
H2AFZ	-0.019805
PLVAP	0.019772
EPCAM	0.019714
DRG1	0.019637
POLR2D	-0.019535
CHCHD1	0.019507
RPL4	-0.019506
CFB	0.019477
BTG1	0.019426
ACPL2	-0.019379
NDUFAB1	0.019260
MGAT4B	-0.019214
PRKRA	0.019204
WBP5	-0.019192
EMD	-0.019142
NQO1	0.019082
ATP5SL	0.019056
CCDC80	-0.018925
SERP1	-0.018838
XBP1	0.018832
CDIPT	0.018793
SPINT2	-0.018729
MRPS12	0.018724
ATP5J	0.018722
RAB21	0.018657
NDUFA10	0.018614
KRTCAP2	0.018571
PUF60	0.018505
MSMO1	-0.018499
EIF4H	-0.018498
PLA2G16	-0.018478
YWHAQ	-0.018478
TUSC3	0.018394
CD81	-0.018381
YTHDC1	0.018322
LAPTM4A	0.018248
TECR	-0.017916
ARHGAP17	-0.017884
HNRNPF	-0.017852
DAP	-0.017828
FKBP5	0.017819
UBE4B	0.017773
THBS4	0.017701
SLAIN2	-0.017678
UBE2E3	0.017648
YWHAZ	0.017647
TM9SF2	-0.017625
CLTA	0.017542
BTF3	-0.017450
ATP5L	-0.017438
OLFM1	-0.017428
USP14	-0.017386
CLTC	0.017362
PCSK2	-0.017337
TM2D3	0.017255
TRIM8	0.017108
TNIP1	0.017087
CCT2	0.017004
ACTB	-0.016994
EIF3D	-0.016921
ATF6B	0.016832
MORF4L2	0.016805
TXNIP	-0.016771
SWI5	0.016758
SGSM3	0.016742
ZFAND6	-0.016672
ABCD3	0.016547
CXXC5	-0.016546
RASD1	-0.016521
RGS9	0.016512
CHPF	0.016482
PTP4A3	-0.016449
TMEM147	-0.016417
MOB4	0.016377
ATP1B1	0.016375
SNURF	-0.016345
DEGS1	0.016340
TIMM23	-0.016330
CRELD2	-0.016313
SARNP	0.016269
STMN1	-0.016186
CMTM8	-0.016182
ITFG1	0.016175
PKIG	-0.016171
BNIP3L	-0.016168
IGSF1	0.016097
PAM	-0.016059
DCN	-0.016001
NDUFV2	0.015939
CUTA	0.015934
CBX3	0.015910
TRAPPC1	0.015860
RTN1	0.015853
SEC24B	-0.015572
CTSV	-0.015484
ATP6AP2	-0.015450
PPA1	0.015421
PSMD11	-0.015394
SCN3B	0.015308
ZNF428	0.015296
RPS11	-0.015289
PSMB8	0.015260
FSHB	0.015140
FKBP3	-0.015093
NPM1	-0.015054
TAX1BP1	-0.015032
DDIT4	0.015031
SOD2	0.015011
ZNF358	0.015009
EPB41	-0.014987
SPARCL1	0.014969
UROD	-0.014969
CTTNBP2NL	0.014945
PENK	0.014913
FAM214A	0.014893
WTAP	-0.014840
PSENEN	0.014839
TSPAN31	0.014838
PSMC4	0.014812
RCN1	-0.014783
AHCTF1	-0.014714
SSR2	0.014679
PFN1	-0.014657
SMIM14	0.014622
TALDO1	-0.014565
CA2	-0.014564
TIMM8B	0.014522
GSTM3	-0.014489
RPL37	0.014473
SOD1	0.014462
THUMPD1	-0.014439
GNG10	0.014383
MNAT1	-0.014346
NAPA	0.014331
SCAF8	-0.014315
SSR4	0.014250
PSMB6	0.014232
AARS	0.014229
MTHFD1	-0.014226
TMEM248	0.014209
CPT2	0.014102
PSMB5	0.014094
CAPNS1	0.014085
AVP	0.014068
TACC1	-0.014034
TMEM106C	0.014025
RPS12	-0.014013
ITM2C	-0.013993
RPP14	0.013992
HERPUD1	-0.013977
SVIL	0.013911
PER1	0.013880
IRF3	0.013873
MID1IP1	-0.013867
ZNF330	0.013862
SIRPA	-0.013857
MRPL52	-0.013822
H2AFY	0.013817
PBX3	0.013804
GNB2L1	-0.013795
NDUFB7	0.013775
CTSB	-0.013742
AVPI1	0.013737
MOCS2	0.013735
THNSL2	-0.013651
KRT8	-0.013640
RPL23	0.013611
SSTR2	-0.013606
PHB2	-0.013596
MDH2	-0.013587
NDUFA6	-0.013574
MKNK2	0.013564
SDHB	-0.013541
ASCL1	0.013451
AMHR2	-0.013406
BASP1	0.013390
SQLE	-0.013359
PON2	0.013352
COX8A	0.013317
FUNDC2	-0.013293
FDFT1	-0.013157
ANXA4	0.013145
HEXA	0.013133
CLU	-0.013128
CDK9	-0.013122
LHB	0.013073
CCNG1	0.013063
TOB1	-0.013059
DHRSX	0.013010
PIGP	-0.012972
PDIA3	-0.012948
UBE2G1	-0.012941
S100B	-0.012926
EEF1D	0.012888
SDF4	-0.012888
GSKIP	-0.012886
NDEL1	0.012846
GLTSCR2	-0.012843
RBM42	-0.012828
PFDN6	0.012827
MRPL13	-0.012818
CHMP2B	0.012809
SMYD2	-0.012798
CNIH1	-0.012798
POMGNT1	0.012785
PCNA	-0.012781
NDUFS7	0.012775
RANBP3	-0.012758
POR	-0.012745
NUP205	0.012668
NGFRAP1	0.012667
RNH1	0.012647
YBX3	0.012635