!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	CHEBI:23965
!cell_type	MCF-7 breast cancer cells
!organism	human
!end_metadata
EGR3	0.086858
RASGRP1	0.070170
IL20	0.069860
KCNK6	0.064100
GEM	0.051956
PMAIP1	0.051690
SGK1	0.050173
SMTNL2	0.049629
TNFRSF11B	-0.049328
PKDCC	0.049186
FOXN1	0.046268
FOXC1	0.046218
DRD1	-0.044221
P2RY2	0.043659
LONRF2	0.043523
LOC400768	0.042410
SGK223	0.041754
FOS	0.041447
HIST1H4C	0.041105
CXXC5	0.040599
NMRK1	0.040261
VASN	0.040006
PCDH8	-0.039933
USP31	0.039776
SYBU	0.039628
TIPARP	0.039162
SLX4IP	0.039048
RHOBTB1	0.037792
VMP1	0.037758
RAPGEFL1	0.037254
RPS11	0.037131
NRIP1	0.037080
FAM110C	-0.036159
MIR21	0.035688
AKAP1	0.035668
BLNK	-0.035492
ARMCX6	0.035464
ELF1	0.035369
C14orf182	0.035297
CCND1	0.035275
FZD7	0.034857
HSPB8	0.034274
KBTBD6	0.034012
PGR	0.033918
SIGLEC15	0.032996
DLG5	0.032352
TGIF2	0.032329
NCEH1	-0.031889
FAM110D	0.031595
LINC00341	0.031092
C8orf46	0.031081
FHL2	0.031074
TMED8	0.031051
MIF-AS1	0.031027
PREX1	0.030895
RBM24	0.030429
IGFBP4	0.030386
ZNF703	0.030363
RALGDS	0.030360
RUNDC3B	-0.030291
SCNN1G	0.030177
ST8SIA4	-0.029681
CCNT1	0.029614
SLC16A6	0.029569
MXD1	0.029440
GARS	0.028996
SLC25A36	0.028970
TSPYL5	0.028933
HHEX	-0.028723
RCL1	0.028644
TSKU	0.028617
GCOM1	0.028528
LOC101928476	-0.028429
STON1	-0.028168
PYY2	-0.028084
LTB4R2	0.028049
ARHGEF26	0.028014
DOK7	0.028013
SSC4D	0.027874
KCNK5	0.027871
PGLYRP2	0.027861
RPL37A	0.027771
UHMK1	0.027742
SLC22A5	0.027456
PIK3R1	0.027454
LRRC25	-0.027356
HSF5	-0.027294
TRIB2	-0.027196
ND6	0.027123
CYP1A1	-0.026970
RUSC2	0.026922
CARD16	-0.026908
ZSWIM6	0.026676
CA2	0.026260
PRKCD	0.026174
SH3PXD2A-AS1	-0.026162
CTGF	0.026107
RAB31	0.026070
FAM124B	-0.026062
MYC	0.025967
PRSS1	-0.025916
SP4	-0.025754
LHB	0.025707
PPTC7	0.025522
ONECUT2	0.025518
LOC100289333	0.025355
BLVRB	0.025298
USP35	0.025254
DNAJB8	0.025169
PTGES	0.025107
AEN	0.025014
LOC100505501	-0.024898
ESF1	0.024874
UBE2T	0.024731
ABTB2	0.024723
TPBG	0.024719
GALNT4	0.024694
HMCN1	-0.024647
MBOAT1	0.024619
RNF43	-0.024563
TOP1	0.024554
ARHGAP15	-0.024448
TNFSF10	-0.024434
TRIM59	0.024390
ZFP91	0.024335
NOP56	0.024305
LBX2-AS1	-0.024272
CEBPB	0.024270
SLC7A5P2	0.024254
IRF2	-0.024108
ID1	-0.024090
SIAH2	0.023956
ACVR1	-0.023908
TMEM238	0.023883
FTX	-0.023811
MGC10814	0.023798
ASB13	0.023775
RND3	-0.023705
KIT	0.023682
CTR9	0.023594
MEIS3P1	0.023532
KCTD6	0.023519
HIST1H4B	0.023518
KRTAP4-12	-0.023501
GTF2H3	0.023286
EGR1	0.023140
ARMC1	0.023131
EIF5B	0.023096
C1orf226	0.023041
WSB1	0.022932
GRAMD3	-0.022848
SERTAD3	-0.022825
THOC5	0.022765
SSB	0.022709
C19orf33	0.022693
TUBB4A	-0.022651
FABP2	0.022626
GAB2	0.022609
TMEM151A	0.022509
BTG2	-0.022496
TMEM181	0.022450
SOCS2	-0.022359
DDHD1	0.022332
SRGAP1	0.022297
TIFA	0.022223
PDZK1	0.022209
ALPP	-0.022174
RPL38	0.022168
MYRFL	-0.022162
HACE1	-0.022160
LOC100132005	-0.022057
PTENP1	-0.022057
NINL	0.021990
POLR1C	0.021988
LOC100506047	-0.021982
SMOX	0.021973
MAS1	-0.021963
SCG2	-0.021957
ATRX	0.021929
TDG	0.021914
CBFA2T3	0.021871
SCYL1	0.021859
SHB	0.021847
KLF4	0.021834
KIAA1033	0.021784
TNKS2	-0.021778
C6orf132	0.021757
KAZN	0.021744
LAIR2	-0.021723
LOC100130428	-0.021698
CAPN10-AS1	-0.021697
RAB11FIP1	0.021673
LOC100130705	-0.021627
FAM83B	-0.021623
PSTPIP2	0.021614
PRB3	-0.021597
SOD3	-0.021578
GPR128	-0.021568
DUSP15	0.021568
CDK2	-0.021543
NOB1	0.021535
SENCR	-0.021525
SLC26A2	0.021516
AMIGO2	-0.021507
FAM63A	0.021502
RP9	0.021483
MIR30C2	-0.021350
C5orf30	0.021349
DDIT4	-0.021330
PSMA7	0.021219
S100A8	0.021209
CCAR1	0.021193
ANKRD36B	0.021147
SPIN1	0.021073
RPL7AP9	0.021060
MREG	0.021059
TULP4	0.021038
CISD1	0.021037
KCNA5	-0.021021
SGK3	0.021009
CXCL12	0.020995
PSMA4	0.020928
CYP11B2	0.020907
HAUS1	0.020901
HNRNPU-AS1	-0.020885
KIF3A	0.020871
KLF10	0.020869
FNIP2	0.020848
SLITRK6	-0.020822
HMOX1	-0.020817
FAM60A	0.020759
GUCD1	0.020703
SNAPC1	0.020645
HLA-DRB1	0.020584
AP1S1	-0.020578
NKAIN1	0.020563
IL34	0.020556
PLOD2	0.020538
MXI1	0.020511
FKBP2	0.020510
KMT2C	0.020500
MICB	0.020492
CHSY1	0.020487
VAV3	-0.020477
SCAMPER	-0.020325
SNORA28	0.020308
PRICKLE2	0.020305
KAT6B	0.020295
DDX17	0.020246
LGI2	0.020240
SLK	0.020221
KIF21A	0.020217
LOC100505478	-0.020189
SLC38A3	0.020169
RAB37	0.020166
TST	0.020155
GSG1L	0.020119
GPR144	0.020106
LINGO1	0.020094
ZSCAN29	0.020072
NPTX1	0.020067
FOXF2	-0.020047
ADRA2A	0.020040
S1PR3	-0.020006
CAV1	0.019981
CCDC59	0.019978
LYAR	0.019946
FLJ38668	0.019916
DHX36	0.019835
AVP	0.019811
IGHE	0.019794
LOC100128416	-0.019774
LOC157860	0.019765
CCNG2	-0.019759
MTPN	-0.019749
SUV39H2	0.019724
PHLDA1	0.019710
HIST1H3G	0.019708
LOC100505774	-0.019687
RBBP8	0.019674
METRNL	0.019638
KIAA1614	0.019636
TMEM159	0.019630
NPFFR1	0.019628
C18orf21	0.019618
NOTCH2NL	0.019613
ARRDC1-AS1	0.019599
LOC728061	0.019557
WDR47	-0.019552
LOC93622	0.019541
C10orf2	0.019528
CNIH2	0.019515
DNAJC1	0.019492
NPEPPS	0.019437
E2F6	0.019425
FOXO4	0.019407
NEBL-AS1	0.019342
EFNB2	0.019333
ACTL9	-0.019328
FMOD	0.019299
FABP5	0.019271
SMG1P5	-0.019247
ZNF562	0.019235
JAK2	0.019221
TWF2	0.019218
TBL1Y	0.019208
TOE1	0.019155
WDR43	0.019151
VAT1L	-0.019144
GLA	0.019140
NXNL2	0.019126
LOC652993	0.019114
MEFV	0.019108
MALAT1	0.019095
SLC30A1	0.019095
NXT1	0.019061
SNHG8	0.019056
HBZ	-0.019056
ANKRD2	0.019035
FOXO3	0.019034
PPRC1	0.018991
RIPK3	0.018987
LOC340178	-0.018975
TNFRSF11A	-0.018973
KITLG	-0.018920
LOC727930	-0.018858
AREG	0.018854
SAA3P	0.018847
OR5L2	-0.018835
APOBEC3C	0.018818
LCN1	0.018811
FGF18	0.018791
ZNF442	-0.018790
ULK1	0.018772
CTNNB1	-0.018768
OK/SW-CL.36	-0.018760
MGMT	0.018756
CD5L	-0.018750
OSGIN1	0.018728
CIB4	-0.018723
PRKCE	0.018680
MRPS21	0.018677
RNF2	-0.018674
DIRAS2	0.018655
LGALS2	0.018654
HIST1H2APS5	0.018650
CHURC1	0.018649
BOLA1	0.018645
SLC36A4	-0.018638
SLC14A1	0.018619
N4BP3	-0.018610
UGCG	0.018578
IFT46	0.018563
GRHL2	0.018561
PPIF	0.018557
CCL2	0.018540
NAT8B	0.018519
DLX2	-0.018519
EPRS	0.018515
F9	-0.018511
GAGE1	-0.018495
EIF3G	0.018494
RPRML	0.018482
SLC10A3	0.018482
RAB8B	-0.018466
TSPAN5	0.018436
UBL5	0.018436
EFNA1	-0.018433
MIR101-1	0.018420
REL	-0.018391
HIST1H2BI	0.018380
VEGFA	0.018365
MPST	0.018361
SNORD89	-0.018345
MRPL17	0.018341
S100A9	0.018335
LOC100131053	-0.018327
SLC6A14	-0.018322
TXN	0.018321
HIST1H2BE	0.018315
SULT2B1	0.018308
ANKRD50	-0.018298
ARHGEF3	0.018291
NET1	0.018253
UBN1	0.018248
ARF6	0.018237
NR3C1	-0.018195
WFS1	0.018154
C15orf56	-0.018147
FOXA3	0.018143
MGC16275	0.018113
C1QTNF6	0.018107
FRMD6	-0.018104
LOC100129550	-0.018078
ARID5A	0.018071
SGOL2	0.018028
FAM86C1	0.018004
CITED2	0.017988
CCT7	0.017975
JARID2	0.017967
AURKB	0.017950
PUS3	0.017947
SLC9A3R1	0.017943
ERP27	-0.017933
HS3ST3A1	0.017919
BAX	-0.017899
RBX1	0.017885
BEX1	-0.017878
NIP7	0.017855
TOP2A	0.017836
BTNL2	0.017828
EFNB1	0.017813
ZNF90	-0.017805
FLJ36840	0.017784
ARHGAP32	-0.017759
PARD6B	0.017758
EGLN3	-0.017744
ENTPD3-AS1	-0.017743
RFPL1S	0.017742
GLIS1	-0.017738
PIK3IP1-AS1	-0.017705
ERN1	0.017691
OTUD6B	0.017687
BRDT	-0.017667
SCNM1	0.017661
CCDC68	-0.017655
CCDC38	-0.017635
ABCA11P	-0.017627
NBPF1	0.017588
SFXN2	0.017586
DIO3	0.017554
MTCL1	-0.017553
SCNN1B	0.017539
PPAP2B	0.017538
FAM86A	0.017533
PIK3R3	-0.017527
ZBTB41	-0.017496
LOC550113	-0.017474
FAM78A	-0.017462
H2BFS	0.017446
PRPS2	0.017407
ZNF205	0.017405
CCDC51	0.017398
FUOM	0.017388
RPL22L1	0.017387
ZFP30	0.017378
TEX28	-0.017373
SCRN1	0.017358
SOX4	0.017356
DEFA4	-0.017343
PMEL	0.017338
TPR	0.017331
DAPK2	0.017322
FFAR2	-0.017278
VEGFC	-0.017256
TRAK2	0.017252
FEM1A	0.017251
ZNF213	-0.017250
LINC01142	-0.017243
PSMB4	0.017239
LOC101927478	-0.017230
TRBC2	0.017218
RPS26	0.017208
ARPC2	0.017200
KCNMA1-AS1	-0.017195
TEAD1	0.017177
PITX1	0.017175
ERGIC1	-0.017172
GDAP2	0.017166
ECE1	0.017157
NFAT5	0.017140
LOC100507630	-0.017137
LOC101927379	-0.017122
MBD4	0.017097
FOXJ3	-0.017096
NUBP2	0.017090
MPLKIP	0.017084
GPATCH2	-0.017080
LRRK1	0.017077
RBM27	0.017071
TAZ	0.017066
LOC100506725	-0.017051
NKX2-2	-0.017044
RELT	0.017043
MYADML2	-0.017043
SNRPG	0.017008
KCNJ3	-0.017008
C19orf26	-0.016983
AJUBA	-0.016976
ASB12	-0.016973
MGA	0.016959
AGO3	0.016947
SRSF7	0.016945
RAB17	0.016924
SNX24	0.016919
SLC51B	-0.016918
POLR2H	0.016907
COMP	0.016905
MSL2	-0.016900
PPAN	0.016896