!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!cell	Liver
!perturbation	Metformin
!Relevant information	0.1% metformin high fat NASH diet
!end_metadata
BHMT	-0.225949
CTSS	-0.167321
G6PC	-0.164406
IGFBP1	-0.157787
ANG	0.156651
APOA5	0.154217
PDK4	-0.147856
LYZ	-0.143900
PPP1R3G	-0.141387
LGALS3	-0.140757
RNASE4	0.119496
GSTP1	0.118204
KRT8	0.106741
FABP1	0.102147
KRT18	0.098882
AHSG	0.091059
LPL	-0.090766
TAT	-0.090527
GOT1	-0.090240
RGN	0.089541
OAT	-0.089406
CLU	0.087178
PSAP	-0.087178
FMO3	0.085813
HSD3B7	0.084321
FGB	0.083002
ITIH4	0.082609
IGFBP2	0.082487
GLUD1	0.081002
RAB30	-0.077696
CA2	-0.073967
GPNMB	-0.073920
APOA4	-0.073754
ITIH3	0.072757
ACTG1	-0.070067
MMP12	-0.069692
GSTM5	0.069636
CLEC7A	-0.069144
PLG	0.069127
NDUFA1	0.067718
FGA	0.066764
ACOT1	-0.066181
FBP1	0.065576
CTSD	-0.065454
APOC4	0.065163
MPEG1	-0.064075
CPS1	0.063927
ERRFI1	-0.063623
CCRN4L	-0.063210
LY6D	0.061831
FGL1	0.061798
TYROBP	-0.061491
AASS	-0.061236
IGFBP4	0.061085
SLC2A2	0.060634
VTN	0.060228
SGK1	-0.060045
DUSP1	-0.060006
CFI	0.058897
CYC1	0.058651
CTH	-0.057253
UGT2B17	0.057172
AGT	0.057047
C9	0.056826
LGALS9B	0.056584
CES1	-0.056559
UGP2	0.056253
KNG1	0.055383
ACADM	-0.053989
CYP1A2	0.053095
C9orf72	-0.052643
HSPA5	0.051885
APOA1	0.051498
SERPING1	0.051200
GPCPD1	-0.049795
VIM	-0.049271
TMPRSS6	0.049250
STARD10	0.049116
COX5A	0.048568
TXNIP	-0.048234
APOC2	-0.048173
DBI	0.047788
OSGIN1	0.047577
FABP5	-0.047431
COX6A1	0.047220
SLC27A5	0.046083
C5	0.045267
COMT	0.044531
OAZ1	0.044499
CD36	-0.044391
EHHADH	-0.043871
LUM	-0.043747
ST3GAL5	-0.043437
SERPINA3	0.043309
RPL3	-0.043001
CRP	0.042842
INMT	0.042838
ENO1	0.042794
MANF	0.041572
MFSD2A	-0.041572
SERPINF2	0.041496
TP53INP1	-0.041233
ATP5B	0.040601
ELOVL2	0.040303
CHCHD10	0.040188
EIF5A	0.040077
GADD45G	-0.039815
CALR	0.039764
FN1	0.039736
IGF1	-0.039728
CTSB	-0.039254
APOM	0.039197
MBL2	0.038806
UQCRB	0.038743
TF	0.038739
SERPINA1	0.038411
DCN	-0.038340
CCBL2	-0.038318
LRG1	0.038218
ENC1	-0.038194
SLC9A3R1	0.038156
CSF1R	-0.037941
COX7A2	0.037794
MORF4L1	-0.037722
SERPINF1	0.037367
CYP2E1	0.037328
CST3	-0.037198
KHK	0.037103
UGT2B10	-0.036958
S100A10	0.036855
BGN	-0.036152
TMEM205	0.036024
CD74	-0.035818
FBF1	-0.035747
PNPLA7	0.035599
RPS27L	0.035591
ITIH2	0.035413
ATF5	0.035221
FMO5	0.034758
F5	0.034645
FGG	0.034188
ATP6V0C	0.034126
G0S2	-0.034041
ALAD	0.033753
RPL13	0.033752
LGMN	-0.033522
ACAT1	-0.033266
RPL7	-0.033246
RNF128	0.032968
PEX11A	-0.032946
UBD	-0.032834
PCNA	-0.032693
GJB2	0.032512
ITGB2	-0.032511
CMBL	-0.032494
HPX	0.032460
SERPINA10	0.032142
FH	-0.032086
PLK3	-0.032003
RPLP0	-0.031995
CDH1	0.031964
GLUL	-0.031839
GC	0.031719
ENPEP	0.031610
CERS2	0.031583
ABCB11	0.031557
ACSL1	-0.031532
XBP1	0.031444
CROT	0.031324
TTPA	-0.031108
CD68	-0.031066
HACL1	-0.030963
AHCY	-0.030955
NUPR1	0.030909
PYGL	0.030898
APOA2	-0.030731
GHITM	-0.030692
ABCC4	-0.030676
CYBA	-0.030493
PAH	0.030441
SLC25A47	-0.030400
RPL38	0.030234
PCBP1	0.030227
LAPTM4A	-0.030074
H6PD	0.029864
NDUFB9	0.029710
CTGF	-0.029595
F9	0.029497
LGALS1	-0.029402
PROC	0.029141
F2	0.029111
BHLHE40	-0.029092
COX6B1	0.029065
C1QC	-0.028904
CSTB	-0.028895
PSMB7	-0.028881
FETUB	0.028816
NRN1	0.028731
SDS	-0.028581
HADHB	-0.028515
ALDH3A2	-0.028203
TFR2	0.028097
COL3A1	-0.028076
SPRR1A	0.028056
SERPINC1	0.028040
RPL6	-0.027826
PSMA4	-0.027794
EDF1	0.027738
PIGR	0.027649
SLC25A22	-0.027265
DDT	0.027107
NDUFA8	0.027102
EEF1A1	-0.027097
SLC10A1	0.026937
COX4I1	0.026908
REEP6	0.026779
AQP9	0.026693
AMBP	0.026659
ATP6V0D2	-0.026538
C1QB	-0.026498
TOB1	-0.026433
RPS14	-0.026322
F13B	0.026276
BNIP3	-0.026193
ABCB4	0.026138
DPYD	0.025721
FDPS	-0.025691
MAT2A	0.025474
HSD17B10	-0.025472
SERPIND1	0.025417
APCS	0.025390
ADI1	0.025385
TKT	0.025326
RPS7	-0.025121
ASS1	-0.025061
ALDOB	0.024869
SOD1	0.024858
PLCXD2	0.024733
SREBF1	0.024708
RPS12	0.024608
ATP5H	0.024576
IFITM3	0.024447
COQ10B	-0.024436
PPIB	0.024369
QDPR	0.024361
HRSP12	0.024227
PHLDA1	0.024088
SERINC1	-0.024061
ACAD11	-0.023862
PTP4A1	-0.023853
LCN2	-0.023831
PRDX1	0.023726
PIM3	-0.023719
NME2	0.023557
EIF4A1	-0.023544
TXNDC12	0.023537
PLA2G12B	0.023469
PCBD1	0.023370
RPL28	0.023297
C1QBP	-0.023235
RPS2	-0.023192
OTC	0.023130
CYCS	0.023117
NDUFV3	0.022765
TUBA4A	0.022725
HPD	0.022688
SUMO1	-0.022686
GCLC	0.022663
USMG5	-0.022651
CLK1	-0.022643
CHPT1	-0.022601
HAO1	0.022562
RPS29	0.022447
COX19	0.022402
ETNPPL	-0.022316
EIF4EBP1	0.022263
MIF	0.022253
ATRAID	-0.022232
CTNNB1	-0.022176
SPP2	0.022053
RARRES1	-0.022053
COL18A1	0.022006
HIST1H2BI	-0.021840
SLC6A13	0.021737
SLC39A4	0.021719
STBD1	0.021524
BAG1	0.021464
RPL36AL	0.021440
EEF1B2	0.021426
IQGAP2	0.021415
SLC22A1	0.021401
AGMO	0.021334
CCNL1	-0.021331
ANXA1	-0.021298
C8G	0.021184
SSR3	0.021094
TMEM37	0.020914
FTH1	0.020896
PAQR9	0.020866
RPL11	0.020864
GCSH	0.020820
EIF5	0.020724
ATP5F1	0.020676
P4HB	0.020607
HGFAC	0.020527
ITIH1	0.020489
FXYD1	0.020470
RARRES2	0.020452
RGS16	0.020452
C6orf203	0.020440
SERPINA6	0.020318
IRS1	-0.020289
PICALM	-0.020260
NDUFS6	0.020240
UQCR11	0.020234
LEAP2	0.020231
TSPAN12	0.020224
CD9	-0.020214
SLC16A1	0.020173
TGM2	0.020160
CEBPB	-0.020066
ALDH1A1	0.020062
PEBP1	0.019992
ALAS1	-0.019944
TGFBI	-0.019904
FABP7	-0.019886
CA3	0.019852
GRHPR	0.019760
NDUFA12	0.019684
CCND1	0.019639
SLC25A5	-0.019625
SAMM50	0.019573
NPC2	-0.019548
LCP1	-0.019423
DHRS4	-0.019393
ECHS1	-0.019368
GAPDH	0.019343
IGFBP7	-0.019225
MARC1	-0.019179
AKR1C4	0.019136
LIPA	-0.019132
HPN	0.019105
HAX1	0.019039
ARSA	0.019029
NDUFS8	0.019006
PSMA3	-0.018965
RETSAT	-0.018955
CKS1B	0.018912
UQCRC1	0.018906
PCK1	-0.018898
SLC25A51	-0.018861
DNAJB9	0.018825
ETFA	-0.018793
HSD17B12	-0.018787
VKORC1	0.018784
ABCG2	-0.018764
SQSTM1	0.018700
NDUFV1	0.018617
AARS	0.018614
MRPL38	-0.018590
DECR2	-0.018553
CPT1A	-0.018548
RHEB	-0.018512
TXNDC5	0.018501
GPX1	0.018470
PPIA	0.018429
TTR	0.018427
MSRB1	0.018353
JUN	-0.018215
TDO2	0.018161
EPHX2	-0.018161
CYB5A	0.018138
GYS2	0.018108
EIF3I	0.018076
ID3	-0.018014
CPN2	0.017985
ZFP36	-0.017985
CD5L	-0.017933
UQCRHL	0.017911
PFN1	-0.017909
C8A	0.017902
IDI1	0.017792
SLC22A5	-0.017791
FAH	0.017714
RPS26	-0.017645
RPL15	-0.017611
GLDC	0.017592
ZPR1	-0.017567
RPS13	-0.017554
CLEC1B	-0.017510
PCTP	-0.017482
CRIP1	-0.017468
ACOX1	-0.017403
PABPC1	-0.017357
AFM	0.017275
PAM16	0.017207
TMBIM6	0.017167
HLA-DQA1	-0.017157
FAU	-0.017143
AADAC	-0.017120
ABHD14B	0.017108
NME1	0.017083
SLC38A3	0.017070
KDELR1	0.017070
TM4SF4	-0.017011
HSD17B11	-0.017009
UBE2D3	-0.017007
ADTRP	-0.016989
RHOB	-0.016982
FABP4	-0.016894
ACTR3	-0.016809
TMEM147	0.016797
PSMA5	-0.016728
C1QA	-0.016721
HINT1	-0.016643
CCS	-0.016637
C1S	0.016630
UBE2V2	-0.016620
TUBA1B	0.016584
MORF4L2	0.016536
CLDN3	0.016517
ZFP36L1	-0.016503
CD164	0.016449
FADS1	0.016440
SH3BGRL3	-0.016439
C11orf24	-0.016389
CS	0.016385
NCKAP1	0.016381
GPX3	-0.016374
AKR1A1	-0.016371
ATP5J2	0.016342
HILPDA	-0.016266
SEC61B	0.016242
PLIN4	-0.016224
VSIG4	-0.016198
HPRT1	-0.016165
FCGR2A	-0.016126
CYP39A1	0.016123
XDH	0.016064
C6orf62	-0.016051
SNRK	-0.016007
HSPD1	-0.015945
ARG1	-0.015912
CCNG2	-0.015895
SGK2	0.015874
SCP2	0.015862
ANXA3	-0.015822
TFB2M	0.015798
SQLE	0.015783
CHCHD2	0.015751
HMBS	0.015692
NDUFB11	0.015678
PHB2	0.015650
RPL22	0.015564
GSTA3	0.015505
SERF2	0.015432
NDUFA13	0.015358
MCFD2	0.015259
GABARAPL1	-0.015249
RPS20	0.015248
ALDH6A1	0.015242
MRPS18B	0.015222
RBP4	0.015193
HAAO	0.015169
CEBPA	0.015148
NDRG2	0.015120
HLA-DRB5	-0.015118
EDNRB	-0.015015
HHEX	0.015006
SRM	0.015003
POLR2I	0.014985
ASGR1	0.014936
TBCEL	0.014921
ATP6V1A	-0.014920
FNDC3B	0.014898
NDUFC1	0.014826
RPL4	-0.014812
RPS8	-0.014812
MPC1	-0.014799
VAMP8	0.014771
CYP4A22	-0.014737
DSP	0.014717
NDUFA3	0.014713
DDIT4	-0.014684
PHYH	0.014681
NAT8	-0.014680
ADAM8	-0.014627
ACOT2	-0.014616
ATL2	-0.014614
SDC1	0.014590
SDCBP	-0.014503
SDC4	0.014482
MTTP	0.014466
PSMA7	-0.014457
ETFB	0.014451
PNP	0.014442
F12	0.014433
ADH1C	0.014415
RTN4	-0.014386
PSMA2	-0.014358