!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Estradiol
!smiles	CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
!drugbank_id	DB00783
!pubchem_cid	5757
!cell_type	Uterus - single injection of 400 ug/kg - 48 Hours after treatment
!organism	mouse
!end_metadata
CA2	0.272188
CLCA1	0.234105
LTF	0.224646
PIGR	0.192916
COL6A3	0.182518
LCN2	0.172115
GSTO1	0.168280
TUBA1B	-0.139572
C3	0.136908
WFDC2	0.123571
LTBP4	-0.121183
TUBA1A	-0.116297
LY6E	0.113059
TUBA1C	-0.110314
BCAT1	0.109496
CTSV	0.095959
DIO2	0.093637
PLET1	0.093239
ELF3	0.092127
TUBB	-0.090859
DSTN	0.084142
PLAC8	0.083191
CKB	-0.080942
FCGBP	0.079828
IFITM3	0.078542
COL6A2	0.075378
RPS3	-0.075141
PABPC1	0.074716
TAGLN	0.074077
A2M	0.071633
TMEM176B	0.071479
GOLM1	0.069918
HK1	-0.068679
GJB2	0.067613
SAT1	0.067560
TMEM176A	0.067438
CP	0.066170
TMOD3	0.065243
RAN	-0.065240
PLP2	0.064599
CNDP2	0.064090
SERPINH1	-0.063330
COL6A1	0.060756
RPL13	-0.060042
HTRA1	0.059701
KRT8	0.058715
SPP1	0.057874
FXYD3	0.057795
ALDOA	0.056480
MYL12A	0.056401
RPS7	-0.055541
FAM213A	0.055297
LDHA	0.055285
LSP1	-0.055238
CFI	0.052418
APP	0.052379
COL1A2	0.052120
GNG5	0.052057
COX6A1	0.050321
CD14	0.049664
HSP90AA1	-0.049444
TACSTD2	0.048819
KRT19	0.048177
CAPNS1	0.047284
ACTG2	0.046920
IGFBP3	-0.046234
B2M	0.046173
RPS11	-0.045068
RPS2	-0.044570
PADI1	0.044410
MED24	0.044233
ARPC3	0.044100
THY1	-0.043951
IER3	0.043790
ID2	-0.043561
CFL1	-0.043181
HMGN1	-0.043152
VMP1	0.043087
PRNP	0.042969
DCN	0.042962
MDK	-0.042519
KCTD12	-0.042401
TGFBI	-0.042113
FMO1	-0.041867
FKBP1A	-0.041692
LGALS1	-0.041691
OGN	0.041565
PCNA	-0.041432
APCDD1	-0.041368
HSP90B1	-0.041307
TRIM28	-0.041193
MGP	-0.040382
ANXA1	0.040297
BPIFB1	-0.040156
CTSB	0.039092
RPL21	-0.039085
HGFAC	0.038835
PLTP	-0.038640
LAMP1	0.038640
TSPO	0.038554
FAM20C	0.038170
MARCKSL1	-0.038126
RPL18	0.037703
SHISA5	0.037577
IMPDH2	-0.037241
ACTB	-0.037112
LGALS3BP	0.036886
UBE2R2	0.036835
LUM	0.036797
NCL	-0.036271
CAPN5	0.036264
IGFBP6	0.036113
MAGED1	-0.035928
ITM2C	-0.035823
SPRR1A	0.035727
GAS6	-0.035675
PENK	-0.035584
GAPDH	0.035342
SOX17	-0.035132
ACTA2	-0.035086
ANPEP	0.034917
ARG1	0.034770
AKR1A1	0.034719
RHOB	-0.034431
SFRP2	-0.034429
CTSA	0.034399
HSD17B11	0.034154
FSCN1	-0.034136
TIMP3	-0.033994
PLEKHB2	0.033871
H2AFZ	-0.033623
TUBB6	-0.033230
TPI1	0.033221
CLDN7	0.033044
GSTP1	-0.032879
CTSD	0.032868
YBX1	0.032813
RPL5	-0.032570
UBA2	-0.032512
GPI	0.032350
TGFB1I1	0.031823
MSRB1	0.031680
MYH11	0.031646
CYBA	0.031646
HLA-A	0.031191
CSTB	0.030862
NDUFB5	0.030854
FBL	-0.030710
TPT1	-0.030597
DYNLL1	-0.030486
ARF1	0.030351
CD164	0.030261
LAMC2	0.029957
SMPDL3A	0.029883
PCP4	0.029843
GSR	0.029745
MFSD4	0.029690
RPS5	-0.029669
ANXA2	0.029647
COL5A2	0.029591
PNPLA2	0.029576
DAP	0.029482
RPL3	-0.029389
PLAT	-0.029377
STMN1	-0.029361
RPS23	-0.029163
UGDH	0.029129
CLU	0.029093
HSPH1	-0.028948
GPC3	-0.028873
JUND	0.028417
SRSF2	-0.028388
KRT7	0.028327
GJA1	0.028115
PROM1	0.028084
CDH5	-0.027980
DDX39B	-0.027785
HOXA11	-0.027740
GNAS	-0.027684
HINT1	-0.027599
CPT1A	0.027316
BSG	0.027179
ISLR	-0.026949
LPP	0.026941
SUMO3	-0.026913
WDR6	-0.026901
MKNK2	0.026798
HSPA5	-0.026776
GDF10	-0.026710
MYH14	0.026661
CRIP1	0.026558
RPLP0	-0.026313
MORF4L1	-0.026220
MYADM	0.025949
POLD2	-0.025875
MPRIP	-0.025857
ACAA2	0.025740
ARPC1B	0.025684
RPS12	0.025549
CEACAM1	0.025517
RPS19	-0.025487
BTG2	0.025447
NUCB1	0.025368
H1F0	-0.025336
RPS17	-0.025320
SHFM1	0.025174
EMP1	-0.025145
RPA1	-0.024976
ZBTB20	-0.024559
PRKAR1A	-0.024512
RIN2	0.024407
UBL5	0.024400
SEC61A1	0.024345
IGFBP4	-0.024342
PNP	0.024257
DEK	-0.024251
EID1	-0.024177
CD9	0.024170
ATP6V1A	0.023974
SNRPD2	-0.023970
GABARAPL1	0.023936
CD63	-0.023899
ATP1A1	0.023885
CTSH	0.023880
BANF1	-0.023743
ACTA1	0.023741
ZFP36L1	0.023735
SLC39A4	0.023700
ECHS1	0.023636
H2AFX	-0.023606
CCT7	-0.023447
ATP6V0E1	0.023385
DAZAP2	0.023278
CHD4	0.023172
H19	-0.023092
CD74	-0.023045
HSPD1	-0.023031
PRKCDBP	0.022749
U2AF2	-0.022673
DDIT4	0.022617
NHP2L1	-0.022585
GTF2I	-0.022367
GNG12	0.022329
LAPTM4A	0.022213
ATP1B3	0.022197
GRB7	0.022184
PRMT1	-0.022050
NPC2	0.022035
RPS15A	-0.022031
SLC44A4	0.022021
ANAPC5	-0.021954
APOE	-0.021893
RPL28	0.021893
LPHN1	-0.021856
ERH	-0.021697
IRF9	0.021677
RPS24	-0.021659
GTF2F2	0.021457
SMOC2	-0.021395
PKM	-0.021306
ZFAND5	0.021251
ALPL	0.021128
CDCP1	0.021050
PLK3	0.021034
HOXD11	-0.020978
CRTAP	-0.020883
GBP4	0.020883
ANGPTL2	0.020769
AP1S1	0.020726
HNRNPH1	-0.020694
PGK1	0.020635
HCFC1R1	0.020630
EIF3K	0.020623
MFGE8	0.020559
SSRP1	-0.020541
CEBPD	0.020448
LMNA	-0.020415
CTDSP2	0.020180
SRM	-0.020135
RPL10A	0.020124
PAPSS1	-0.020110
TGIF1	0.020007
CSNK1G2	-0.019986
RNASEK	0.019924
MSN	-0.019869
NDUFV1	-0.019867
MAGED2	-0.019834
CYFIP1	0.019821
RHOQ	0.019800
WDR92	0.019782
CALB1	-0.019778
ENG	-0.019720
EEF2	-0.019655
HNRNPD	-0.019645
TIMM13	-0.019635
RAMP3	0.019610
FAM3D	0.019581
SAR1A	-0.019541
ACSS1	0.019472
ANAPC11	-0.019385
EHMT2	0.019311
RPL10	0.019271
ID3	-0.019187
CDK2AP1	-0.019148
RPS27A	-0.019109
CNBP	-0.018924
LSM7	-0.018857
BHLHE40	0.018763
B4GALT1	0.018741
RNF10	0.018736
TWIST2	-0.018667
KLF4	0.018595
CYC1	-0.018580
MRFAP1	-0.018532
MCM5	-0.018497
LRRC58	-0.018471
IDH2	-0.018453
RARRES2	-0.018422
TMEM165	-0.018401
FOXO3	0.018384
PGLYRP1	0.018380
CEBPB	0.018330
NDUFS2	0.018299
C9orf16	0.018265
LAMP2	0.018252
CA12	0.018225
CHCHD10	0.018218
GSN	-0.018201
PSMB10	0.018168
GRN	0.018041
VAMP8	0.018030
GSK3A	-0.017981
SQSTM1	0.017954
PSMC2	-0.017934
TCF19	-0.017899
ELOVL5	0.017865
COL1A1	0.017847
CNN3	-0.017816
SERPING1	0.017814
SPOCK2	-0.017793
AES	-0.017668
ITIH5	0.017605
COL15A1	-0.017594
GLI1	-0.017592
TP53INP2	0.017505
CKS1B	-0.017466
CD93	-0.017412
ARHGDIA	-0.017393
HGS	0.017376
ATOX1	0.017338
DDAH2	-0.017326
EZR	0.017323
ARMC10	0.017283
RPL6	0.017247
HIGD2A	0.017242
F3	0.017142
YPEL3	0.017133
TCF21	-0.017022
RGS3	0.016889
TRIM25	0.016844
AZIN1	-0.016827
CYB5A	0.016827
DNAJA1	-0.016824
GPX3	0.016700
ARF5	0.016636
SPTBN1	-0.016614
GABARAP	0.016580
ISG15	0.016533
NDP	-0.016532
TRA2B	-0.016494
ZMYND11	-0.016471
GADD45A	0.016463
ARPC2	0.016429
DSP	0.016427
PERP	0.016416
RELA	0.016393
SERINC3	0.016313
POSTN	-0.016279
KRT18	0.016269
MCM7	-0.016267
PSMD3	0.016258
TCN2	0.016214
FKBP4	-0.016152
ALAS1	0.016151
TCF12	-0.016119
G6PD	0.016091
NPNT	-0.016039
EIF1B	-0.015924
C14orf2	-0.015894
PRKAB1	0.015882
SOX4	0.015866
CBX6	-0.015845
PADI2	0.015807
NDUFA7	0.015750
CDC42SE1	0.015737
GATA2	-0.015731
INHBB	0.015674
ELAVL1	-0.015669
PKDCC	-0.015650
TMPO	-0.015641
MCM4	-0.015628
PTP4A1	0.015594
RPL8	-0.015586
SNRPB	-0.015562
AKT1	-0.015561
CCNA2	-0.015535
RNASE4	0.015515
MCM3	-0.015478
PSMA3	0.015374
RANBP1	-0.015359
HDC	-0.015335
MMP14	0.015320
SNX6	0.015315
ACTG1	0.015249
ARFGAP2	0.015247
NAGA	0.015245
WDR5	-0.015244
IMPAD1	-0.015168
EMD	-0.015128
RNF149	0.015033
LLGL2	0.014959
HNRNPA2B1	-0.014939
GPS1	-0.014910
WBP1	-0.014824
AHNAK	-0.014759
ARFGEF1	0.014757
LRG1	0.014714
CRYZ	0.014670
EEF1D	-0.014644
ALOX15	0.014574
PSD	0.014543
HOXB6	0.014537
MYH9	-0.014523
MSX1	-0.014519
CBX3	-0.014519
POLR2G	-0.014495
RASA4	0.014480
ST6GALNAC2	0.014478
IL10RB	0.014417
SOX7	0.014406
RPL7A	0.014399
ID1	-0.014392
ARMCX2	-0.014374
HSD11B2	0.014339
SVIL	-0.014318
RPS10	0.014307
MBTPS1	-0.014236
CCND1	-0.014134
TUBB3	-0.014104
UBE2L3	-0.014098
UHRF1	-0.014080
SMC4	-0.014062
UQCRHL	0.014034
SDHD	0.013960
C5orf15	0.013955
SMDT1	0.013950
MRVI1	0.013946
DNMT1	-0.013934
ATPIF1	0.013917
FKBP9	-0.013859
FTO	-0.013852
CPXM2	-0.013830
GBP2	0.013802
CLDN3	0.013788
KCNK1	0.013714
EPHX1	0.013696
GADD45G	0.013688
LGALS9B	0.013668
C15orf39	0.013621
PABPN1	-0.013617
PTGES3	-0.013614
SOCS2	0.013613
LAMB3	0.013581
ISOC1	0.013572
DNAJC10	-0.013568
RPS28	0.013547
GPC1	-0.013509
CTSS	0.013484
MCM2	-0.013462
RPL7	0.013452
CFH	0.013428
SIVA1	-0.013406
COL7A1	0.013366
RMND5A	0.013364
ARGLU1	-0.013333
TMED10	0.013313
RRAGA	-0.013305
LGALS3	0.013295
MLF2	-0.013286
CLK1	0.013244
NT5DC2	-0.013205
KDM3A	0.013188
ITM2B	0.013173
PCBP1	-0.013149
SEPT7	-0.013144
SPARCL1	-0.013066
SRSF11	-0.013051
AAMP	-0.013046
PSMB8	0.013027
WBP5	-0.013007