!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!cell	MCF10A 
!cell subtype	MCF10A PIK3CAH1047R 
!perturbation 	GDC0941 treatment (inhibition)

!gene	PI3K
!entrez gene 	5290
!disease	Breast cancer
!end_metadata
F3	-0.206578
DDIT4	-0.192730
TUBB6	-0.184668
TUBA4A	-0.180844
TUBB2A	-0.153991
TUBB4B	-0.133729
CTGF	0.133035
BTG1	0.119954
TUBB3	-0.116637
SGK1	0.111779
EPS8	0.108406
DYNLL1	-0.106951
ACTC1	-0.102417
SERPINE1	-0.096197
KLF10	-0.091393
YWHAG	-0.091175
HSPA8	-0.090928
CHSY1	-0.087310
MIR21	0.082787
ADM	-0.080430
HSPA1A	-0.078512
PTK2	0.077587
CCNG1	0.077252
SERINC1	0.076818
NNMT	0.074711
TNFRSF12A	-0.069794
TXNIP	0.069635
PLK2	-0.067877
HIF1A	-0.066942
SAT1	0.066831
DKK1	0.065903
TUBB	-0.065100
IER3	-0.064057
CEBPB	0.062186
HSPB1	-0.060421
RIN2	0.059622
FHL2	-0.059211
HMOX1	0.059140
LBH	0.057050
CITED2	0.057048
FRMD6	-0.055400
PNRC1	0.054690
CDKN1B	0.054348
CSRP1	-0.054113
SNAI2	-0.053776
ERRFI1	-0.053653
TMEM158	-0.053344
IVNS1ABP	0.053114
TUBA1C	-0.052575
MXI1	0.051845
GPX4	0.051535
KLHDC2	0.050965
TUBA1B	-0.050939
FGF2	-0.049771
ZYX	-0.049245
PLAT	0.048829
VMP1	0.048622
ITM2B	0.048558
SPDL1	-0.048113
TM4SF1	0.047928
CLIC1	-0.047648
CCNG2	0.047622
KRT18	-0.047011
SPHK1	-0.046664
IRF2BPL	-0.046623
GLUL	0.046576
FOXD1	-0.046515
KRTAP2-3	-0.046358
UBL3	0.046220
DPYSL2	0.046155
TUFT1	-0.046031
IGFBP3	-0.045279
HOXC6	0.045061
PGRMC2	0.044552
NEXN	0.044057
MAP3K7CL	0.043813
LINC00968	0.043048
ATP2B1	-0.042949
RND3	0.042896
DDX21	-0.042025
ISCU	0.041958
BHLHE40	-0.041459
INSIG1	-0.041391
SDC4	-0.041390
KRT34	-0.041227
BNIP3	-0.041107
CTSB	0.040898
HNRNPAB	-0.040703
FAM57A	-0.040629
IL18	0.040431
SDCBP	0.040385
NTN4	0.040231
GADD45A	-0.040149
CTDSP2	0.039917
ACLY	-0.039697
RAN	-0.039285
SERINC3	0.039023
KPNA2	-0.038661
MAT2B	0.038444
MAT2A	-0.038404
PAIP2	0.038003
MYADM	-0.037936
SRXN1	-0.037769
SNX9	0.037706
PLOD2	-0.037601
CALHM2	0.037326
UAP1	-0.036868
JUP	0.036855
SFN	-0.036826
SNHG5	0.036664
ATP1B1	-0.036643
DCN	0.036563
SOX4	0.036561
CAMLG	0.036540
CCT2	-0.036460
PFN1	-0.036208
C20orf24	-0.036154
YWHAZ	-0.036049
MT1HL1	0.035881
MIR22HG	-0.035767
PCBP1	-0.035733
MAP7D1	-0.035481
RPL36	0.035463
MAFB	-0.035396
EFNB2	-0.035183
SRSF2	-0.035153
LGALS1	-0.035127
C12orf5	-0.034632
ETF1	-0.033801
HBP1	0.033587
HSP90AB1	-0.033290
PABPC3	0.033046
RAD21	0.033034
FBXO32	0.032789
FAM46B	-0.032691
CCND1	-0.032641
H2AFZ	0.032502
PEA15	-0.032377
STK38L	-0.032225
PPP1R15B	-0.032218
ACTB	-0.032198
SLC38A2	0.032120
KRT17	-0.032091
HSD17B11	0.032054
RRAGA	-0.031963
ELL2	-0.031962
DEK	0.031694
DDX5	-0.031509
HSP90AA1	-0.031497
CEBPD	0.031463
SEMA3C	0.031417
NME7	-0.031288
ACTG1	-0.031284
ZNF804A	0.031150
ENAH	-0.031121
C15orf61	0.030887
WEE1	0.030840
CXCL8	0.030802
NEK7	-0.030799
CCT3	-0.030739
FNBP1L	0.030711
AK3	0.030526
MT1F	0.030482
FHL1	0.030463
EIF4A1	-0.030331
BCAR3	-0.030308
KLHL7	0.030113
GPR137B	0.030051
BPGM	0.029919
NDRG1	0.029902
RPL36A	0.029899
EIF3E	0.029826
ITGAV	0.029738
SEPP1	0.029675
APP	0.029576
PSAP	0.029416
COX6C	0.029377
DNAJA1	-0.029280
OSBPL9	0.029280
PSMG2	0.029251
UBE2S	-0.029190
ADAMTS5	0.029163
STARD4	-0.029130
VGLL3	0.029053
MRPL3	-0.028938
ACTN1	-0.028793
C11orf24	-0.028692
SLC7A5	-0.028614
IP6K2	0.028596
PHLDA2	-0.028567
GAPDH	-0.028543
HPS5	0.028319
SCO2	-0.028305
CAV2	-0.028293
FAM214A	0.028254
PRR16	0.028162
SNHG8	0.028137
RDH10	-0.028109
GLIS2	-0.028016
CCDC28A	0.027999
NEAT1	0.027934
PTP4A2	-0.027820
RBM12	-0.027769
DNAJB4	-0.027730
HK1	-0.027711
RPL34	0.027631
JUN	-0.027560
IRS1	-0.027541
STK39	-0.027500
TPST2	-0.027446
HPCAL1	-0.027442
SLC25A32	-0.027378
COTL1	-0.027354
C6orf62	0.027258
VCL	-0.027238
PMEPA1	-0.027172
MSMO1	-0.027048
PKM	-0.026924
ITGA5	-0.026884
COX20	-0.026760
MAP2K1	-0.026754
CHMP2B	0.026728
DST	0.026710
PAM	0.026600
HLA-A	0.026514
RASA1	0.026369
IER2	-0.026351
FSCN1	-0.026256
ZFAS1	0.026244
PXDN	0.026241
AMOTL2	-0.026153
PPAP2B	-0.025967
CRIM1	0.025841
AKR1C3	0.025734
MAPRE1	-0.025700
AK4	-0.025669
BLCAP	-0.025606
RAB10	-0.025603
KRT16	-0.025487
ASUN	-0.025463
CDV3	-0.025379
KRT81	-0.025344
CYC1	-0.025304
CNN3	-0.025281
VEGFA	-0.025249
LINC00657	0.025237
TMSB10	-0.025225
HMGB2	0.025197
PIM1	0.025021
DEGS1	-0.025009
TMEM258	0.024959
BZW1	-0.024919
SLC16A3	-0.024893
UQCRFS1	-0.024815
COX1	-0.024653
BASP1	-0.024597
GTPBP4	-0.024577
PFDN2	-0.024537
SOCS5	-0.024398
KYNU	0.024377
VPS4B	0.024354
C1orf198	-0.024252
SRP19	-0.024243
PAWR	0.024220
UHRF2	0.024181
CDCA7L	0.024088
GDI1	-0.024053
TMEM123	0.024035
GRN	0.023959
RPS8	0.023939
GAB2	0.023893
GABARAP	0.023877
RB1CC1	0.023864
ODC1	-0.023819
ATF4	0.023779
NT5C3A	0.023743
KRT5	-0.023655
CCNDBP1	0.023585
MLLT11	-0.023461
MTHFD2	-0.023435
MT2A	0.023411
EEF1B2	0.023321
EAPP	0.023285
ANXA1	0.023262
EGLN1	-0.023197
SCG5	-0.023164
TSG101	0.023041
TWIST1	0.023018
NOP58	-0.022979
SERPINH1	-0.022958
TIPARP	0.022953
CHST3	-0.022867
GLRX2	-0.022803
AMD1	-0.022794
ARF4	-0.022734
TMA7	-0.022726
ADRM1	-0.022700
CYBRD1	0.022674
KIF5B	-0.022658
ABCB10	-0.022645
IFFO2	-0.022620
ABCE1	-0.022543
EIF4A3	-0.022531
HLX	0.022509
GRPEL1	-0.022460
SRSF3	-0.022457
CORO1C	-0.022433
YIPF5	0.022344
MAPK1IP1L	-0.022319
SMIM14	0.022302
CTSA	0.022283
STC2	0.022278
UBB	0.022213
FAM134C	0.022165
DHX15	-0.022089
TIMP2	0.022061
BRD8	0.022051
TMEM14C	0.022019
CFL2	0.022004
TGFBI	-0.021928
BNIP3L	0.021916
FOXP1	0.021817
IGF1R	0.021799
CARD6	0.021747
ARSJ	-0.021744
NAV1	-0.021713
RSRP1	0.021576
PCDH18	0.021542
EIF2A	0.021501
RSL24D1	0.021377
MAP1LC3B	0.021367
HIST1H2AC	0.021351
YPEL5	0.021341
CAP1	-0.021312
GYS1	-0.021277
OXTR	-0.021239
EVI2A	0.021227
NFE2L2	0.021227
RNF44	0.021113
RAB1A	-0.021104
CREG1	0.021031
YPEL3	0.021018
RPLP0	-0.020995
AMIGO2	-0.020976
RPL41	-0.020927
RPL39	-0.020900
PUM1	0.020857
GBE1	0.020763
NOP56	-0.020746
FBLIM1	-0.020712
PLSCR4	0.020707
DNAJB1	-0.020692
CTNNAL1	0.020643
SGMS2	0.020572
DDOST	0.020556
CD99	0.020500
PFDN5	0.020478
ANKRD27	-0.020393
RRM2B	0.020374
COPRS	-0.020352
PKD2	0.020319
PLS3	0.020311
UBC	-0.020257
CXXC5	-0.020256
SH3BGRL	0.020225
F2R	0.020220
VASP	-0.020193
NME1	-0.020124
KLHL24	0.020087
TNFAIP8	0.020021
PUF60	-0.020006
PKIG	0.019979
TUBA1A	-0.019971
H3F3B	-0.019966
ZFYVE1	0.019904
GREM2	0.019900
TMEM50A	0.019882
CHMP5	0.019854
VEGFC	0.019821
SARAF	0.019821
SHROOM3	0.019803
NTAN1	0.019763
PRDX5	0.019757
ENC1	-0.019707
S100A2	-0.019699
PGM1	-0.019672
LAMB1	0.019647
ENO2	-0.019638
IRS2	0.019564
AIDA	0.019558
S100A13	0.019536
MRPS24	0.019473
CHIC2	0.019469
OS9	0.019456
UBQLN2	-0.019419
PRDX4	0.019411
FIBIN	0.019364
AIM1	-0.019279
ATRAID	0.019244
MYBL1	-0.019243
IRX3	-0.019229
KCTD11	-0.019227
TMEM245	0.019225
GABARAPL1	0.019171
RNASE4	0.019147
TEX2	-0.019141
ID1	-0.019120
ANXA2	-0.019118
DYNLT1	-0.019099
IARS	-0.019096
PTGES3	-0.019088
MRPL36	-0.019060
CD81	0.019057
CCT6A	-0.019019
KRT10	-0.019006
DDX41	-0.018962
MICAL2	-0.018889
TIMM17A	-0.018865
PIK3C2B	-0.018863
SMIM15	-0.018856
PSMD14	-0.018825
MOK	-0.018822
CYB5R3	0.018813
TDP2	0.018806
USP53	0.018803
FOXQ1	0.018769
KCTD3	0.018726
TXNRD1	0.018707
ARL6IP5	0.018706
UBE2E3	0.018697
QARS	0.018656
SRP14	0.018649
MAPK7	-0.018601
SH3BP4	0.018581
LOX	0.018568
RIC8A	-0.018556
ENO1	-0.018552
VDAC2	-0.018545
MITF	0.018524
PTPLB	-0.018507
DHX40	0.018490
SRGAP2C	0.018478
MRPL17	-0.018475
TAGLN	-0.018420
SLC35E2B	0.018359
ACTR3	-0.018351
EIF3H	0.018337
GLRX	0.018335
GBP2	0.018326
DDR1	0.018325
RGS19	-0.018286
PERP	0.018260
CBR3	0.018222
BIRC2	0.018198
KRTAP1-5	0.018181
WRB	0.018154
GOLPH3	-0.018145
FERMT2	-0.018014
FMN2	0.017998
TMEM14A	-0.017995
LBR	-0.017937
HSPE1	-0.017934
OXSR1	-0.017934
HSPH1	-0.017904
DNTTIP2	-0.017851
MIF	0.017838
VAT1	0.017786
LTBP1	0.017785
ZMAT3	0.017785
STAG2	0.017785
LARP1	-0.017774
MRFAP1L1	0.017765
SH3D19	0.017736
UBE2D1	0.017722
FSTL3	-0.017693
ARPC1B	-0.017691
MTCH1	-0.017689
HEBP2	0.017660
PPP2CB	-0.017614
KIAA1191	0.017585
ABHD4	0.017581
SPOCK1	0.017581
ID3	0.017571
TCEAL4	0.017535
PTMA	-0.017530
PINK1	0.017518
LINC01279	0.017516
PDHX	0.017466
KRT8	-0.017460
TMEM189	0.017452
PCMTD2	0.017430
HES4	-0.017430
SEC61G	-0.017414
C10orf10	0.017409
HK2	-0.017386
RPL35	0.017386
HLA-C	0.017383
GCNT1	-0.017320
NUPR1	0.017306
UQCRQ	0.017277