!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Phenytoin
!smiles	C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3
!drugbank_id	DB00252
!pubchem_cid	1775
!cell_type	brainstem
!organism	rat
!end_metadata
COX1	-0.244910
TTR	0.240397
RPL9	0.224490
PTGDS	-0.208355
RPL26	0.139351
RPS15A	0.136061
NEFH	0.134510
USMG5	0.134421
RPL17	0.130720
RPL13A	0.130139
BCAS1	0.126105
RPL37	0.122766
GFAP	-0.120634
COX7B	0.117186
RPS12	0.115299
RPS21	0.111364
MOBP	0.105448
RPS14	0.102627
CYTB	-0.101113
RPL31	0.100667
COX7A2	0.099899
RPS27A	0.098720
RPS4Y1	0.093001
RPS19	0.091804
RPS17	0.090686
RPS20	0.086594
APOD	-0.083473
QDPR	-0.079186
RPL5	0.076701
MRFAP1	0.075254
RPL38	0.074750
RPL21	0.072750
UQCR10	0.070796
ZWINT	-0.068750
RPS8	0.068028
SERINC1	0.067813
TECR	-0.065845
RPL27	0.065761
RPL24	0.064540
ATP5J2	0.064533
RHOB	-0.063543
RPS16	0.063229
PBX3	0.060589
NDUFA1	0.060587
MGST1	-0.060332
GLUL	-0.058060
TIMM8B	0.057025
SLC22A17	0.056880
ALDOA	-0.056694
NDFIP1	0.056685
NDUFB11	0.056257
EIF4A2	0.054857
RPS25	0.053952
RPS29	0.053102
GABRA1	0.052931
HSP90AB1	-0.052873
DBNDD2	-0.052421
VDAC3	0.052230
RPS26	0.050517
NAP1L5	0.050254
EEF1B2	0.049781
RPL27A	0.049558
RPS15	0.048389
TPT1	0.047944
RPS23	0.046915
RPS28	0.046703
CKB	-0.045974
NDRG2	0.045668
MAG	-0.045420
RESP18	0.045008
RPL6	0.044859
ND3	0.043667
NDUFB9	0.043482
TXN	0.043381
APOE	-0.043169
CHCHD2	0.042925
DBI	0.042819
HSPE1	0.042595
RPS9	0.041756
RPL19	0.041625
RPL23	0.041586
COX4I1	0.041484
CHCHD10	0.040920
MAPT	-0.040604
PPT1	-0.040545
ALDOC	-0.040467
SCG2	0.040400
ENO1	-0.040351
AGT	-0.039871
NDN	0.039840
SPARCL1	0.039774
ACTB	-0.039548
PFDN6	0.039416
NTSR2	-0.039013
EML2	0.038924
NDUFA6	0.038873
LY6H	0.038390
RPS3	0.038356
GAPDH	-0.038331
FABP7	-0.038311
UQCRB	0.037775
RPL30	0.037763
COX6A1	0.037250
RPL4	0.037236
SEPT4	-0.037069
AARS	-0.037002
RPS5	0.036893
RPS11	0.036072
UQCRC1	0.036049
H2AFZ	0.035897
TPI1	-0.035867
RPS6	0.035827
NDUFA2	0.035755
WSCD1	-0.035417
SERPINE2	0.034897
YWHAH	-0.034875
TMA7	0.034723
HSPA4	0.034368
ATP1A2	-0.034229
ATP5L	0.033485
ITIH3	0.033389
RPL35	0.033335
TMEM41B	0.033297
SRP14	0.033149
RPL12	0.033039
TUBB4A	-0.033003
RPL7	0.032879
ACTG1	-0.032826
UQCRHL	0.032777
MAP2	0.032377
PLP1	0.032120
NDUFB5	0.032108
PSMB6	0.031973
EEF1A2	-0.031337
ID2	-0.031066
CPLX1	-0.030754
ATP6V1D	-0.030726
YWHAG	0.030706
TMEM130	-0.030628
CNP	-0.030268
S100B	0.030040
CFL1	-0.029621
RPL36AL	0.029595
RPN1	0.029589
SWI5	0.029547
RPS10	0.029427
UQCC2	0.029425
RPL10	-0.029414
NDUFB3	0.029340
NDUFC2	0.029259
ATP5H	0.029201
RTN4	0.029180
ND2	-0.029067
TMEM59	0.028460
NAP1L2	0.028435
RTN1	0.028108
CALB1	-0.028052
DNM1	-0.028018
DYNLL2	0.027489
NAPB	0.027227
RPS7	0.027181
ARF1	-0.026927
ENPP2	0.026777
RPL18A	0.026740
VSNL1	0.026689
C1QL1	-0.026647
INA	-0.026477
MOG	-0.026470
PCBP2	0.026453
MTCH1	-0.026425
OLFM1	-0.026390
SEPW1	0.026367
HSPA8	-0.026284
NDUFA4	0.026133
SLC20A1	-0.026117
PAFAH1B1	0.026100
POMP	0.026092
EIF3M	0.026034
FTH1	-0.025873
GPM6A	0.025825
GDI1	-0.025771
COPS6	0.025760
SHFM1	0.025676
HINT1	0.025572
UQCRQ	0.025497
ATP5O	0.025487
PGK1	0.025398
NDRG1	-0.025344
MTMR6	0.025309
ITFG1	0.025113
KLHL9	0.024893
TRH	-0.024889
PFDN5	0.024631
SPTAN1	0.024628
ELOVL1	-0.024531
ALCAM	0.024530
PPP2CB	-0.024517
C12orf57	0.024458
HOXA5	-0.024454
SLC3A1	-0.024417
ATP5F1	0.024381
MOCS2	0.024272
TXNDC15	0.024258
NDUFB6	0.024233
ACYP2	0.024202
SARNP	0.024073
GABRG2	0.024071
CD81	0.024057
TSPYL4	-0.023986
PSAT1	-0.023985
NEDD8	0.023957
CST3	-0.023930
REEP5	0.023881
PLEKHH1	-0.023717
METRN	0.023590
SLC25A4	-0.023582
GSTM2	-0.023380
RND2	0.023375
TAGLN3	-0.023318
TSPAN7	0.023314
MOB4	0.023300
RPL10A	0.023208
VIM	-0.023157
NDUFC1	0.022950
PIP4K2A	-0.022926
SDHC	0.022827
IDS	0.022745
RAN	0.022741
SULF2	-0.022718
PLCL1	0.022662
ATP5G3	0.022659
SEC61G	0.022579
MPC1	0.022530
TXNIP	-0.022402
RNASEK	0.022267
ERH	0.022261
RPL11	0.022258
PPP1R3C	0.022187
RBM5	-0.022122
ENO2	0.022103
RETSAT	-0.022079
ATP5J	0.022049
PCSK1N	-0.022047
TSC22D3	0.022014
RPLP0	0.021979
DHX9	0.021961
NEK7	0.021957
MRPL33	0.021865
MGST3	0.021792
PSMB1	0.021637
DPYSL2	0.021634
PRPF19	0.021617
HYPK	0.021613
CLU	-0.021545
GRINA	0.021488
PPP1CB	0.021477
NDUFS7	0.021396
UBA3	0.021145
NCDN	-0.021115
CMPK1	0.021081
TSPYL1	0.020853
MBP	0.020792
SDHD	0.020770
RCN2	0.020766
SPARC	0.020633
GPM6B	0.020583
PCNA	-0.020573
SUMO1	0.020486
GSTM3	0.020472
GLUD1	-0.020396
NCL	0.020331
FGF13	-0.020260
AGPAT4	-0.020235
EIF3E	0.020125
INSIG1	-0.020104
RPL28	0.020084
GSTP1	-0.020032
EVI2A	-0.020021
TOMM7	0.019998
COX7A2L	0.019896
BRSK1	0.019760
ACBD5	0.019755
PAM16	0.019604
ATP6V1C1	0.019527
CAT	-0.019455
LAMP2	-0.019435
LINGO1	-0.019387
NAT8L	0.019365
MRPL20	0.019320
LAMTOR2	0.019270
NNAT	-0.019259
SNCB	-0.019214
MEA1	0.019068
GPX1	0.019066
NDUFB2	0.019058
NDUFS2	0.019006
GOT1	0.018984
NACA	0.018937
DDX17	-0.018846
ATP5G1	0.018802
GABARAPL1	0.018788
FAU	0.018782
SFR1	0.018748
CNN3	-0.018741
C1D	0.018697
ITM2B	-0.018649
SCN1A	0.018601
RHOG	-0.018591
PRKAR1B	0.018585
PLLP	-0.018570
LDHB	0.018428
MRPL41	0.018363
CMAS	0.018337
PGRMC1	0.018283
ERMN	0.018210
SUB1	0.018128
SEP15	0.018119
CD83	0.018112
LYZ	-0.018096
RELL2	-0.018052
SERINC3	-0.018023
CAMK2G	0.017982
LRRC58	0.017944
NME2	0.017817
TBCA	0.017744
MORF4L2	-0.017733
HSP90AA1	0.017723
ENOPH1	-0.017710
UBE2O	-0.017611
HOXB5	-0.017578
SF3B6	0.017556
VDAC1	0.017530
GLOD4	0.017528
CD9	-0.017477
NRSN1	0.017466
DCTN1	-0.017417
NDUFA12	0.017282
HSPA5	0.017259
PLCXD3	0.017252
TALDO1	-0.016999
PDHA1	-0.016982
LIMK1	0.016966
RTCB	-0.016961
SLC25A3	-0.016930
CLIP2	-0.016891
TRIM2	-0.016809
PRKCSH	-0.016794
FLOT1	0.016793
LXN	-0.016735
ABHD3	0.016596
DAO	0.016556
HNRNPH1	-0.016548
GARS	-0.016495
DHX15	0.016480
NDUFS3	0.016445
EMC7	-0.016427
COX2	0.016424
TMEM176B	-0.016410
TPPP3	-0.016405
ATP1A3	0.016402
FNTA	-0.016353
PFDN2	0.016248
MCTS1	0.016209
POLR2K	0.016187
YTHDF2	0.016175
CDC37	-0.016152
COX14	0.016081
RPS2	-0.016049
MLLT11	-0.016017
SLC25A46	-0.015973
ASPA	-0.015966
TOMM20	0.015961
RTN3	-0.015959
CXCL14	-0.015880
FDPS	-0.015863
NDFIP2	0.015831
DNAJB9	0.015802
ATP6V0B	0.015777
KCNA2	0.015732
RAC1	-0.015728
PRNP	-0.015697
RPN2	0.015674
EDNRB	-0.015647
GDI2	-0.015551
RHOA	0.015485
FN1	-0.015458
CD74	-0.015449
ARHGDIA	-0.015449
OCIAD1	0.015354
PAQR6	-0.015311
MYRF	-0.015282
GCSH	-0.015249
NDRG4	0.015192
LPAR1	0.015185
SLC3A2	-0.015047
MAP1A	0.015034
TUBB2B	-0.015028
DBP	-0.015022
RAB11B	-0.015005
SQLE	-0.014970
RAD21	0.014944
SH3BGRL	0.014865
ARPC4	0.014813
MTX2	0.014783
KAT2B	-0.014692
SGK1	0.014682
EIF6	-0.014680
SST	0.014673
BTG1	-0.014656
OGDH	-0.014653
SPP1	0.014643
VAMP1	0.014615
IMPDH2	-0.014585
LMTK2	0.014585
CNBP	-0.014557
CHST1	0.014547
CPE	-0.014543
MDK	0.014521
COA3	0.014480
PNP	-0.014460
UBC	-0.014427
RABAC1	0.014372
HADHB	-0.014328
TPP1	-0.014317
ACY1	-0.014219
PSMC1	0.014208
RPL22	0.014192
EMC4	0.014146
NUP153	0.014136
SYNJ1	-0.014099
STMN2	-0.014088
BAP1	0.014085
PSMD14	0.014058
CTXN2	0.014052
CHCHD1	0.014024
ROMO1	0.014006
MRPL18	0.013998
UCHL1	0.013990
OXCT1	-0.013960
DAD1	-0.013925
OSTC	0.013899
PTPLAD1	0.013880
RPSA	0.013873
RNF5	-0.013807
ANKRD46	-0.013804
SCG5	0.013785
CRYZL1	0.013780
GHITM	-0.013756
GPRASP1	0.013697
EPS15	0.013694
FLCN	-0.013680
ATP5A1	-0.013680
EEF2	0.013656
UBQLN1	-0.013651
EIF3F	-0.013631
CDK2AP1	-0.013628
DEGS1	-0.013626
RAB18	-0.013607
HP1BP3	-0.013554
PTP4A1	0.013537
PHPT1	0.013536
HINT2	0.013529
CRH	-0.013499
KRAS	0.013490
COX17	0.013465
MATR3	0.013451
IDH3G	0.013414
PDIA3	0.013413
TRAK1	-0.013412
SNRPN	-0.013397
SYTL2	-0.013364
ATF4	-0.013344
CALB2	0.013343
SLC12A2	-0.013340
SNRPD3	0.013330
TM2D3	0.013305
TMX3	0.013286
STK32C	0.013270
FKBP2	0.013187
GPX8	-0.013163
CNRIP1	0.013153
ATP6V1E1	-0.013147
SYP	-0.013121
KIF5C	0.013112
GSTA5	0.013110
GPLD1	-0.013092
G3BP2	0.013092
UBE2V2	0.013079
ILK	-0.013060
TTYH2	-0.013058
BHLHE40	-0.013023
POLR2L	0.013015
RPL14	0.012992
CEND1	-0.012975
SCOC	0.012974
TM7SF3	-0.012968
YWHAQ	-0.012940
DYNC1H1	0.012868
PAQR4	-0.012856
SEPT8	-0.012851