!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Permethrin
!smiles	CC1(C(C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C
!drugbank_id	DB04930
!pubchem_cid	40326
!cell_type	Frontal Cerebral Cortex - 1mg/kg
!organism	rat
!end_metadata
TTR	-0.182907
ARC	-0.108663
AVP	0.086123
CDHR1	-0.076548
EOMES	-0.074891
NR4A1	-0.073832
NIT2	0.066990
FOS	-0.062196
PXMP4	-0.061527
TBCCD1	-0.059659
TMEM33	0.058147
NQO2	0.052471
PBX3	-0.051562
EGR1	-0.051478
CALB2	-0.049465
JUNB	-0.048572
ABCG2	0.047268
CMSS1	0.045852
KLF4	-0.041886
EGR2	-0.041882
CWC25	-0.041034
TRH	-0.041011
CACNG8	-0.040248
SLC13A3	-0.039930
AHI1	-0.038842
ATF5	-0.038515
HYOU1	-0.038104
PDCL	0.037581
TH	-0.037300
CD302	-0.037142
ALAS2	0.037071
SOSTDC1	-0.037064
VPS37A	0.036678
KCNS3	0.036427
GRIA1	-0.036402
PIK3R1	0.036294
IER2	-0.035622
CCND2	-0.035452
CAMK2A	-0.034690
CPLX2	-0.034452
RPUSD1	0.034337
SLC12A3	-0.034016
DNAJA3	-0.033948
SOGA1	-0.033698
DUSP1	-0.033548
GNAI2	-0.033497
LGI1	0.033419
NT5DC1	-0.033266
RAMP3	0.033154
MEX3B	0.033140
ASAH2	0.033099
ZKSCAN1	0.032884
FOSB	-0.032708
TSC22D2	0.032456
ALKBH2	0.032267
DEGS2	0.032202
ZC3H6	0.032165
GPSM1	-0.031977
ZDHHC20	-0.031817
YTHDF2	-0.031645
UBN2	-0.031540
ACTA2	-0.031531
AKAP5	-0.031290
WDR18	0.031212
GRM7	0.031189
NMBR	0.031129
DLX1	-0.031042
TRIO	-0.030891
KIF5A	-0.030877
KCNS1	0.030770
GOLGA2	-0.030706
LEPREL2	-0.030686
PTK2B	0.030589
CLK1	-0.030517
RC3H2	0.030394
TAF15	-0.030374
STAB1	-0.030319
ZBTB41	-0.030080
DUSP6	-0.029896
TAGLN	-0.029882
SRCAP	-0.029765
SNX14	0.029727
ST8SIA5	0.029666
EML2	-0.029345
GOLPH3	0.029324
FBXO27	0.029255
MAP1A	-0.028933
FRG1	-0.028851
KLF10	-0.028760
GNAQ	0.028729
FAR1	0.028721
SLC6A11	-0.028580
ARL2	0.028381
CDH22	-0.028371
SH3BGRL	-0.028299
PVALB	0.028257
PRKACB	0.028178
SYNE2	-0.028162
RAI1	-0.027964
COA4	0.027923
GBA2	-0.027923
PRPF39	-0.027747
SPARC	-0.027729
HPS6	0.027672
SNRNP70	-0.027540
GSK3B	-0.027508
SGCA	0.027468
TMEM108	0.026861
CORT	0.026836
SSFA2	-0.026783
KDM6B	-0.026774
CDC27	0.026742
XK	0.026678
RASSF5	0.026619
LSM5	0.026477
NEUROD6	0.026475
DUSP5	-0.026470
ATN1	-0.026327
LURAP1L	0.026015
BCKDK	0.025952
KIF1A	-0.025868
ADAM10	0.025847
MYL9	-0.025792
CCNK	-0.025792
AKAP8L	-0.025626
SLC3A1	-0.025619
PAOX	0.025618
ZCCHC17	-0.025600
LHX2	0.025531
S100A5	-0.025512
MAL2	0.025423
SLC7A4	0.025415
LENG8	-0.025406
IGFBPL1	-0.025380
ENDOG	0.025309
AGO2	-0.025283
FABP7	-0.025271
GATSL2	-0.025271
RFNG	0.025135
SLC32A1	-0.025115
YARS2	0.025108
PPP1R9B	-0.025034
LIX1	-0.025013
BLOC1S6	0.024969
CNN1	-0.024935
CDCA7	-0.024929
DDX42	-0.024888
TBR1	0.024820
PCBP3	-0.024803
PAX6	-0.024756
LEPROTL1	0.024728
DNMT3A	-0.024704
GRIN2C	-0.024681
CORO1C	-0.024678
FAM219A	-0.024678
HNRNPUL1	-0.024633
PPP1R36	-0.024623
SSR1	0.024621
CAMK1G	0.024564
GLT8D1	-0.024559
USP7	-0.024520
RB1CC1	-0.024492
KCNC2	0.024388
TRNP1	-0.024245
IGFBP6	0.024241
PPAP2C	0.024171
ITIH3	-0.024168
HIPK2	-0.024138
COX6A2	0.024073
PANK1	0.024031
PRRC2A	-0.023966
CTSS	-0.023958
TNNC2	0.023953
COL4A2	-0.023900
PPP6C	0.023849
GIGYF1	-0.023818
ZC3H7B	-0.023816
DDX6	-0.023811
DNPH1	0.023762
MAP3K1	-0.023711
COTL1	-0.023691
TLE4	0.023678
CEP95	0.023667
LBH	-0.023663
RPA3	0.023641
PAFAH1B1	-0.023563
RLF	-0.023525
LRG1	0.023479
CPSF6	0.023466
UBE2W	0.023414
SHISA3	-0.023408
HNRNPA2B1	-0.023383
CRK	0.023331
CHST8	0.023280
PAMR1	0.023233
NMNAT2	-0.023221
TMEM261	0.023207
BTG2	-0.023170
KLHL14	-0.023135
DCLRE1C	-0.023087
ARL16	0.023072
NELFCD	0.023053
KIAA1217	0.023046
PLAGL1	-0.023025
CARTPT	-0.022978
FBXO30	0.022912
SHANK3	-0.022910
SOX10	-0.022907
SGCB	0.022885
ASNS	0.022856
RASGRP1	0.022801
MAGT1	0.022750
ABHD10	0.022675
SEC24A	0.022670
SOBP	-0.022603
KCNV1	0.022599
AKIRIN2	0.022595
FEM1C	0.022591
DR1	0.022527
TRAK2	-0.022524
CNTNAP1	-0.022512
IDUA	-0.022509
CTGF	-0.022500
MAP4K4	-0.022443
ADAM22	0.022439
ALDH1A2	-0.022393
EXOSC4	0.022385
PNISR	-0.022383
EMR1	0.022381
SGPP1	0.022298
SLC51A	-0.022278
COQ2	0.022268
ZNHIT3	0.022267
ADRA2C	-0.022256
HDHD3	0.022253
CHAC2	0.022243
NNAT	-0.022221
ACTA1	0.022214
PDE1A	0.022201
SCN2B	0.022177
TRIT1	-0.022141
UBE2G1	0.022091
REEP6	0.022083
MSRA	0.022083
ARHGAP25	-0.021967
SULT2B1	0.021904
ACSF2	-0.021891
LRRC8B	0.021879
NTRK2	-0.021866
RBM15	0.021865
FAM58A	0.021807
HMOX1	0.021794
POLR2J	0.021766
PRPF6	-0.021752
NCL	-0.021746
BMPER	0.021712
CACNB3	-0.021704
MYH11	-0.021704
OTUD4	0.021676
RND1	0.021665
SFRP5	-0.021641
FOXS1	0.021625
IFNGR2	0.021610
STK32C	-0.021581
ETV5	-0.021522
DUSP15	0.021504
GLTSCR2	-0.021487
GAL3ST1	0.021349
FLNA	-0.021330
EYA2	-0.021294
TMEM47	0.021290
ECE2	-0.021220
PLEKHH3	0.021193
TNFRSF11B	0.021170
GEMIN8	0.021161
TCEANC2	0.021147
EXTL2	0.021120
CRYAB	0.021096
FDXR	0.021093
STK4	-0.021052
ABCC1	-0.021043
NECAB3	0.020992
R3HDM2	-0.020990
AGAP1	-0.020978
SHMT2	0.020952
PNMAL2	-0.020923
THRSP	0.020882
CDK5R1	0.020869
MFSD3	0.020839
AGAP2	-0.020796
IGFBP2	-0.020770
AIPL1	0.020757
AMIGO2	-0.020745
CMTM7	0.020735
GRM5	0.020732
IRS2	-0.020681
ARMCX4	0.020681
PTPRO	-0.020664
GJB1	0.020657
MPRIP	-0.020646
AEBP1	-0.020644
JAG1	0.020643
SCAND1	0.020608
N4BP1	-0.020608
SSSCA1	0.020607
LRFN5	0.020599
GLUD1	-0.020575
TPRN	0.020570
STX1B	-0.020560
BET1	0.020560
ZNF385A	-0.020558
RBM39	-0.020500
CTNND1	-0.020489
HHATL	0.020488
PLCG1	-0.020446
ASB6	0.020433
NR4A2	0.020409
RPL17	-0.020406
TRAM1L1	0.020400
NECAB1	0.020387
PREPL	0.020367
PRPH	-0.020340
LSM8	0.020338
BHLHE22	0.020321
RSU1	-0.020317
PDCD2L	0.020311
GEMIN4	0.020300
NFIL3	-0.020287
KIAA0430	-0.020235
ARL8B	0.020220
RBM11	0.020218
DGKI	-0.020203
PCSK1	0.020180
POC5	0.020177
TMEM65	0.020165
PRSS22	0.020154
PEF1	0.020139
HMBOX1	-0.020105
TDRD3	-0.020099
ADCY9	-0.020079
WDR6	-0.020074
FBXL15	0.020062
SHANK1	-0.020051
LANCL1	0.020045
TTLL1	-0.020038
CHSY3	0.020012
H2AFY	-0.020008
ZNF180	-0.019972
CSDC2	-0.019972
EIF2S3	0.019915
TM7SF2	0.019914
COG3	-0.019906
RUFY3	0.019896
CDC42EP5	0.019886
PPP2R3C	0.019884
LRRC41	0.019878
SLC9A5	-0.019862
IQUB	-0.019855
CELSR3	-0.019852
PFKL	-0.019815
TSSC1	0.019791
CCNL1	-0.019790
ETFA	-0.019786
LAMB2	-0.019783
TTC14	-0.019772
NUMA1	-0.019758
WDFY1	-0.019756
RBM22	0.019742
CHD3	-0.019735
WDR33	-0.019733
CTBS	0.019729
NLK	0.019711
TRAPPC2L	0.019708
HIST2H4A	-0.019704
ARHGAP5	-0.019700
BMP4	0.019698
MED30	0.019682
PARP8	0.019660
LMBR1	0.019627
RETSAT	0.019624
TSPYL4	-0.019620
RAB6A	0.019614
RB1	0.019598
YBX1	-0.019579
MACROD1	0.019565
HCFC2	0.019564
HNRNPL	-0.019556
MED11	0.019555
NPRL2	0.019554
CYB561	0.019547
METTL5	0.019541
ARHGAP15	0.019536
CCDC8	-0.019533
GSKIP	0.019528
ZNF189	-0.019516
RPL5	-0.019507
CHERP	-0.019487
NOA1	0.019452
DLGAP4	-0.019447
CCND1	-0.019436
NUTF2	0.019425
ZNRD1	0.019416
STARD3	0.019400
TAF11	0.019394
TBX18	-0.019340
PSRC1	0.019335
BMP3	0.019326
SLTM	-0.019314
SYT12	0.019283
KCNK4	0.019282
AKAP8	-0.019257
TAF1B	0.019241
PCSK2	0.019234
PKD1	-0.019230
EEF1E1	0.019217
KIAA1715	0.019200
PRLHR	-0.019186
OSTC	0.019180
BTG1	-0.019174
MIS18A	0.019165
PPP1R14A	0.019165
GRIN1	-0.019102
DENND4A	0.019082
ARPP19	0.019065
EPN1	-0.019057
APTX	0.019048
TMEM243	-0.019018
KCNIP4	0.018980
CERS2	0.018957
ST5	-0.018935
PPIL1	0.018924
CASKIN2	-0.018916
ZC3H18	-0.018901
ZHX3	-0.018897
CEBPZ	-0.018873
SLC9A6	0.018864
KCNJ10	0.018857
AGA	-0.018831
ARID4B	-0.018812
CD99L2	0.018806
BCAS1	-0.018798
ATP1A3	-0.018797
TNFRSF19	0.018787
ENTPD3	0.018783
TCF19	0.018783
ENPP1	0.018782
GRIK5	-0.018777
TUBB2B	-0.018767
PARM1	0.018750
GPR26	0.018726
BNIP2	-0.018725
MTMR11	-0.018724
ST6GALNAC2	-0.018721
FAM53A	0.018716
TCTEX1D2	0.018715
ZNF706	0.018696
ANKRD37	0.018680
NDUFA5	0.018647
REEP3	0.018636
GMDS	0.018632
CHURC1	0.018632
GSTO2	-0.018617
ECI2	-0.018602
ATL2	0.018600
CHST2	-0.018597
SCN3A	-0.018595
ALOX15	0.018584
DCX	-0.018579
GGNBP2	-0.018555
UBXN11	0.018545
SFXN5	-0.018524
BRE	0.018502
ADRM1	-0.018501
GNAO1	-0.018487
CRHBP	0.018478
PRSS23	-0.018466
RFX4	0.018453
WDTC1	-0.018449
SLC25A19	0.018439
STRN3	-0.018435
RABEPK	0.018428
RPL37	-0.018422
PKMYT1	0.018422
POLH	-0.018417
BCAT2	0.018409
GPR123	0.018401
GPR83	0.018395
PARG	-0.018392
LUC7L3	-0.018392
NUDT3	-0.018385
TRNT1	-0.018346
NPY1R	0.018341
SSRP1	-0.018333
RPL4	-0.018322
SPP1	-0.018322
PRR12	-0.018322
SLC4A4	-0.018289
TM9SF3	0.018275
GHDC	-0.018267
RAB4B	0.018259