!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!cell	Locus coeruleus
!perturbation	Braak stage 5
!disease	PD
!end_metadata
PDIA3	0.071279
NBPF14	0.069120
CHODL	-0.064750
AMICA1	0.061082
C15orf27	0.060558
RHOT2	0.055499
CAPS	0.055441
MET	-0.054887
GAL	-0.053802
SPAG8	0.052135
ABLIM1	0.051835
CYB561	-0.050608
FLJ30901	-0.049675
RALGDS	0.049660
FBRSL1	-0.049141
HIRA	0.049108
NAIP	0.048629
SPPL2B	-0.048404
LOC155060	0.048255
NFYB	0.048023
FAM181B	0.047904
KIAA1456	0.047718
PACSIN3	0.047082
SAT2	0.046444
ALK	-0.046333
LOC389831	0.046306
PAX6	0.045564
NUP50	0.045314
EIF3K	0.045273
IL21R	-0.045136
ZNF710	0.045037
NBPF1	0.044985
AFAP1L2	0.044527
MARVELD1	0.044526
GLIS1	0.044347
CHP2	-0.044119
ITPKA	0.044113
KIAA0485	0.043871
NEBL	0.043644
ST18	0.043507
PDCD10	0.042376
MAOA	-0.041846
RASSF8	0.041692
PPP1R17	0.041689
FOLR1	0.041494
C1orf194	0.041471
RNF19A	0.041438
ALDOA	-0.041408
P2RY14	0.041209
ABCA6	0.040979
DLK1	-0.040734
PCSK6	0.040632
PSORS1C2	-0.040519
ATP6V0E2	0.040495
RYBP	0.040419
HSD17B6	0.040090
OGFRL1	0.040085
LPPR1	0.039616
ADAMTS7	-0.039363
TRIM9	0.039301
ZBTB20	0.039184
MPDZ	0.039165
THEM5	-0.039128
GIMAP6	0.039012
DYNLRB2	0.038945
MDGA1	0.038912
GNG13	0.038788
CRYZ	0.038504
ODF3L2	-0.038092
MCL1	0.037975
HNRNPA2B1	0.037846
PVALB	0.037836
NCEH1	0.037756
TXNDC9	0.037719
RAB26	0.037603
LRRC23	0.037336
AMT	0.037325
SOX17	-0.037238
SOX2-OT	0.037010
PLEKHF2	0.037006
CIRBP	0.036990
SSTR2	-0.036842
HEPACAM	0.036762
SYT1	-0.036678
GPR153	-0.036579
FNDC3B	-0.036519
RNF146	0.036275
LIMA1	0.036120
NUMB	0.036077
SYNPO	-0.035996
PLXNB1	0.035796
CCNG2	0.035781
CTDSPL	0.035640
BHLHE23	-0.035560
FLII	0.035508
CA11	0.035347
MRPL11	0.035327
THEG	0.035312
TTC17	0.035188
HTR2A	-0.035096
ZNF492	0.035007
IRX3	-0.034872
TMEM120B	0.034856
HERC2P7	0.034784
ARPP21	0.034745
ZSCAN10	-0.034739
IGFBP5	0.034654
TMEM201	-0.034654
RUNDC1	0.034643
NNAT	0.034615
CCDC47	0.034353
HELZ2	-0.034167
IQCD	0.034166
OLIG2	0.034165
NEAT1	0.034130
FAM71F1	-0.034123
P4HA2	-0.034053
CAPN3	0.034044
HNRNPDL	0.033994
CT47A11	-0.033898
KMT2B	0.033847
SV2C	-0.033811
GJA1	0.033808
CPOX	0.033805
KCNJ16	0.033799
B4GALT2	0.033684
PLXNB2	0.033674
CCL2	-0.033615
ITPR1	0.033614
MTUS1	0.033588
PAN3	0.033434
TYMS	0.033376
RNASE1	0.033362
DOHH	0.033360
PGM5	0.033293
SEMA3B	0.033268
SRSF6	0.033194
SF3A2	-0.033102
AKIP1	0.033015
ABRACL	-0.032953
MAFG-AS1	-0.032793
NDFIP2	0.032720
ADD3	0.032640
KCNJ2	0.032580
PHPT1	0.032470
SPON2	0.032399
FOXC2	-0.032397
PARP4	0.032330
CFH	0.032311
RDX	0.032227
GPR124	0.032114
CD4	-0.032061
SLX1A	0.032015
C11orf39	0.031954
UST	0.031913
PCBP1-AS1	0.031857
CNTNAP1	0.031746
OCLN	0.031621
CHGB	-0.031621
CDC5L	0.031620
MOBP	0.031580
TRIM35	-0.031543
RND3	-0.031469
ELOVL1	0.031458
EWSR1	0.031396
CCDC78	0.031301
CSNK1E	0.031246
KIAA1755	0.031210
ZMAT4	-0.031172
UGT8	0.031136
SIN3B	-0.031121
EVI2A	0.031076
DNMT1	0.031050
SLC16A8	-0.031016
CCDC146	0.031008
CBLB	0.030961
MYO15B	0.030960
LMO1	0.030887
CHST13	-0.030807
DDIT4	0.030775
CSPG4	0.030743
KIAA1683	0.030660
CTNNA1	0.030641
LOC100507140	0.030603
CRIP1	0.030591
KLF9	0.030512
ADARB2	0.030493
LINC00667	0.030440
LCE1C	-0.030287
SOX8	-0.030203
NKD2	-0.030149
LPAR1	0.030089
TUBGCP6	0.030017
COLEC12	0.029996
CCDC144B	0.029981
ZNF280D	0.029972
ABCB1	0.029950
ZBTB48	0.029911
ELOVL7	0.029853
SDCCAG3	0.029852
PI16	0.029835
AHNAK2	-0.029806
CDR1	-0.029792
RGS4	-0.029776
CDH23	0.029775
TMTC1	-0.029718
FRZB	0.029639
ABLIM3	0.029638
SYN1	-0.029574
PLEKHB1	0.029561
PLEKHG5	0.029536
ATG4C	0.029529
C2orf68	0.029481
RGAG4	0.029481
ACTA2	0.029472
SSH3	0.029425
DCLK1	-0.029418
SLCO1A2	0.029289
ZFX	0.029158
GLDN	0.029149
GDNF	-0.029145
SCGB3A2	-0.029131
PPP1R11	-0.029121
NFIA	0.029117
SLC26A10	0.029035
COL8A2	0.029030
HMGN2	0.029029
TMEM246	-0.028965
C16orf93	-0.028914
BAX	0.028909
SBF2	0.028858
ARL8B	-0.028812
ITGA6	0.028766
BAZ2B	0.028762
PIP4K2A	0.028757
DLGAP3	-0.028737
HNRNPH1	0.028735
PBXIP1	0.028679
ARHGAP4	0.028648
PPM1B	0.028610
CYB5R3	-0.028507
TANGO2	0.028474
PEG3-AS1	-0.028441
TPD52L1	-0.028402
POLM	-0.028324
ARID3A	0.028298
ABCA2	0.028276
RBCK1	0.028275
CCND1	0.028271
STAG2	0.028234
TAZ	0.028232
MAN2A1	0.028178
CTNNB1	0.027963
ZNF767P	0.027961
FBXO10	-0.027848
LZTS1	-0.027795
GSR	-0.027761
PLAC4	0.027728
CXCL12	0.027587
HLA-DRB5	0.027577
DCBLD2	-0.027567
CLEC18B	0.027483
CCDC153	0.027460
FAM124A	-0.027441
HSPA2	0.027423
EVX1	-0.027375
SLC41A1	0.027335
ECHDC2	0.027301
CEP290	0.027285
TRIM2	0.027174
CLUH	0.027138
PLCH2	0.027103
DOCK9	0.027095
JADE1	0.027067
NEIL1	0.027066
FAM214A	0.027066
LRRC1	0.027043
ATXN1	0.027040
SF3B3	0.027034
PLEKHG3	0.027010
OIP5-AS1	0.027000
ZMYM6NB	0.026994
PILRA	0.026984
QKI	0.026958
LOC399491	0.026942
HP	0.026942
TMEM98	0.026907
EIF4H	0.026865
SNX10	-0.026792
INSIG1	-0.026766
TINCR	-0.026759
MICAL3	0.026750
PPAP2C	0.026747
MGC45922	-0.026733
NINJ2	0.026724
CCDC88B	0.026720
LYSMD1	0.026704
CASKIN2	0.026649
NIT2	-0.026626
HENMT1	-0.026565
PER1	0.026449
CDC42	-0.026434
CSNK1G2	-0.026413
TOB1	0.026363
PLEKHF1	0.026324
PLAT	0.026324
MOB4	0.026308
CLIC4	0.026305
CCNL2	0.026289
KCNJ10	0.026276
ULK3	0.026240
RFTN2	0.026237
UACA	0.026235
PDE8A	0.026182
DEK	0.026115
TMSB4X	-0.026112
GRASP	0.026103
TCF7L2	0.026075
LOC389199	-0.026037
DLAT	-0.025989
CRYBG3	0.025986
CA2	0.025894
SLC44A1	0.025882
SUGT1	-0.025834
PDLIM3	0.025825
C22orf15	0.025753
RSRP1	0.025734
RAVER1	-0.025733
SORCS3	-0.025691
GIPR	-0.025681
ITIH5	0.025675
FAM118B	0.025673
OSBPL11	0.025648
BST2	0.025632
ABCG1	0.025623
ANKRD13B	0.025606
SREBF1	0.025580
BBS5	0.025568
CADPS	-0.025539
CACNA2D2	0.025531
KAT2B	0.025522
CAMK2N2	-0.025495
MTSS1	0.025424
KLF15	0.025344
PPP2CB	0.025327
ZNF704	0.025324
SKIV2L2	0.025299
MIR22HG	-0.025270
SLC1A3	0.025268
TCF12	0.025263
C18orf54	0.025248
LOC286382	0.025167
LRRC45	0.025133
ARID4B	0.025083
LRCH1	0.025057
ZCCHC17	-0.025054
S1PR5	0.025053
C10orf10	-0.025030
MEGF11	0.024982
PIK3C2B	0.024939
PPFIBP2	0.024868
ANKRD65	0.024861
TTC31	0.024855
MYRF	0.024854
IFI27	-0.024815
MSI2	0.024810
KCNA4	-0.024692
ZSCAN25	0.024680
CYB5R1	-0.024672
TSTD1	-0.024669
NDUFAF2	-0.024653
CREB3L1	-0.024615
KCNQ1DN	0.024602
NTN4	0.024577
SSU72	-0.024503
KHNYN	0.024472
ZNF83	0.024468
STMN2	-0.024441
LDHA	-0.024380
QSOX2	0.024376
TMEM204	0.024360
MFI2-AS1	0.024286
ABAT	-0.024264
OLFM2	-0.024262
NSF	-0.024248
ITGB3BP	0.024245
CLK4	0.024243
CASP8AP2	0.024238
MED13L	0.024238
PCID2	0.024219
PCM1	0.024197
RRAGC	-0.024141
PAGR1	0.024138
THUMPD2	0.024127
PICALM	0.024117
SPOCK2	0.024102
DKK3	0.024089
BRICD5	0.024068
METTL7A	0.024056
RHBDD2	-0.024012
HPN	0.023961
MAVS	0.023958
LINC01420	-0.023955
SMC3	0.023930
OSBPL8	-0.023899
GANAB	0.023879
SPSB4	-0.023865
BPHL	-0.023837
HLA-DMB	0.023836
FAXDC2	0.023831
GPR156	-0.023777
BRD1	0.023776
LINC00839	-0.023731
SMAD7	0.023690
GRM3	0.023622
ZNF177	0.023571
CEP192	0.023548
RNF157-AS1	0.023528
LPL	0.023516
SBF1	0.023514
LSS	-0.023501
HN1	-0.023500
ACAT2	-0.023492
PDK4	0.023479
TMEM53	-0.023473
POU5F1	0.023453
EDN1	-0.023430
TELO2	0.023410
COL4A5	0.023377
PDGFC	0.023370
NCALD	-0.023302
FAM95B1	0.023296
ATP10A	0.023273
ZNF664	0.023236
RAI14	0.023195
VWCE	0.023189
LOC100506725	0.023189
GOLGA2P7	0.023166
PMP2	0.023156
PWWP2A	0.023141
RAB3IP	0.023139
ITM2B	0.023130
CYP4F30P	-0.023126
RASGRP3	0.023117
UNK	0.023113
LINC01278	-0.023100
HSP90AA1	-0.023084
PACS2	0.023081
GPR37	0.023064
CAD	0.023013
IQCK	0.022967
TMEM209	0.022962
TOP1	0.022948
NHSL1	0.022929
NES	0.022910
PIK3R1	0.022891
PSME4	-0.022880
STOM	0.022873
MAMLD1	-0.022871
KAT8	0.022860
RABL6	0.022835
RHO	-0.022792
TTC21A	0.022776
PFKFB3	0.022763
UTF1	-0.022754
CCL4	-0.022750
CALN1	0.022735
C1QTNF5	0.022694
SELENBP1	0.022691
UBA3	0.022681
FOLH1	0.022678
CXXC1	0.022677
FBXL2	-0.022653
DYNC1LI2	0.022637
APC2	-0.022597
PSEN1	0.022589
MUTYH	0.022580
MPP3	0.022575
ZFYVE28	0.022573
NKX1-2	-0.022557
MRAP2	-0.022531
EPHX3	-0.022522
MYO5A	-0.022497
TXNIP	0.022486
GOLGA2P10	0.022461
TNFSF10	0.022459
ZSWIM5	0.022441
PLTP	0.022382
TRPM3	0.022359
HLA-DOA	0.022354
RHBDL2	0.022332
OCRL	-0.022326
ATAD2B	0.022311
RGMB	-0.022301
KISS1R	-0.022297
SHROOM3	0.022268
CSE1L-AS1	-0.022259
MEGF9	0.022224
GSTM3	-0.022211
HIST1H2BE	0.022210